CH2117: Environmental Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH2117
External Subject Code 101045
Number of Credits 10
Level L4
Language of Delivery English
Module Leader Dr Andrea Folli
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module provides you with insights into the chemistry of the natural environment and will enable you to learn the physical and chemical properties of planet Earth’s atmosphere, soils (lithosphere), and natural waters (hydrosphere). 

It is a fundamental component for understanding the causes of natural phenomena, including our weather, seasonal changes, and physical-chemical factors responsible for sustaining life on Earth.

You will also examine how the finely tuned natural chemistry and physics can be unbalanced by anthropogenic (from the Greek ànthrōpos, human + genesis, origin, i.e., human-made) activities, as we will devote particular attention to the causes and effects of the current Climate Emergency. 

These include emissions of greenhouse gases and global warming, sea levels rise, pollution, ozone depletion, and the latest research to combat these deleterious effects.

By exploring all these different aspects, you will witness how the basics of inorganic, organic, and physical chemistry that you have learned in other Year 1 courses come into play in the natural environment. 

The course will also equip you with skills that will facilitate your progression through Year 2 and above. 

On completion of the module a student should be able to

By the end of this module, you will be able to: 

  • Formulate a clear understanding of fundamental atmospheric chemistry, soil chemistry, and water/solution chemistry, including solvation, pH, and fundamental physical properties of water. 

  • Synthesise the basics of acid/base, radical, and redox chemical reactions, exercising critical judgement in evaluating sources of information. 

  • Reflect on the intricate workings of complex natural phenomena involving a delicate interplay between inorganic, organic, and physical chemistry. 

  • Reflect on anthropogenic (i.e., human-made) causes of the Climate Emergency and the UN’s Sustainable Development Goals. 

  • Compile an original piece of work in the form of a deck of PowerPoint slides, handouts, white board, models/props, or visualizer, to communicate complex ideas effectively, contributing to discussions, and deliver, accept, and act on constructive feedback. 

How the module will be delivered

 

The module will be delivered as a blend of face-to-face lectures and digital learning which will also be used to enhance the classroom learning experience, provide in-depth analysis of the Module Learning Outcomes (MLOs) and Programme Learning Outcomes (PLOs), provide support, and feedback, and deliver on the Graduate Attributes (GAs).

The module comprises 10 weeks of 2 1-hour lectures (i.e., 2 hours of face-to-face lecturing per week), three 2-hour workshops, and 1 online test. 

Skills that will be practised and developed

Whilst studying this Module, you will practise and develop the following skills. 

 

Academic skills: 

 

  • Describe the principles of atmospheric photo physics and photochemistry, including atmospheric radical chemistry. 

  • Describe the fundamentals of hydrogen bonding. 

  • Present elements of inorganic chemistry associated with ionic species in solution, including fundamentals of coordination and redox chemistry. 

  • Presents the main causes of air, soil and water pollution and propose remediation technologies. 

 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:  

 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Understand organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Graduate Attributes – Assessment:    

 

Coursework           100% 

 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities. 

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience. 

  • Listen to and take account of the views of others. 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate and present with impact. 

  • Deliver, accept and act on constructive feedback.  

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Understand organisations, their stakeholders and their impact on the community. 

  • Actively take responsibility for promoting human rights, celebrating diversity and widening inclusion 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Understanding organisations, their stakeholders and their impact on the economy 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture  

Goal 3. Ensure healthy lives and promote well-being for all at all ages 

Goal 6. Ensure availability and sustainable management of water and sanitation for all  

Goal 7. Ensure access to affordable, reliable, sustainable, and modern energy for all 

Goal 12. Ensure sustainable consumption and production patterns  

Goal 13. Take urgent action to combat climate change and its impacts  

Goal 14. Conserve and sustainably use the oceans, seas, and marine resources for sustainable development  

Goal 15. Protect, restore, and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss. 

 

 

How the module will be assessed

The module will be assessed via one summative assessment at the end of the course (see below). 

 

Group Presentation (100% of the final mark) 

The final assignment will assess your ability to discern spurious from correct information and test your data analysis skills and some of the fundamental Learning Outcomes for this module. These include stratification and physical-chemical properties of the atmosphere; solution chemistry, including quick and easy calculations of solution pH; and soil properties. Questions relate to atmosphere, hydrosphere, and chemistry of the soil.  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

The reassessment is in the same format as the original assessment, and it continues to meet the module level learning outcomes.

Summative assessment: The summative coursework will provide an opportunity to demonstrate knowledge and understanding of the syllabus content and to research and analyse information and to present these findings in written form.  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:   

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

Assessment Breakdown

Type % Title Duration(hrs)
Presentation 100 Group Presentation N/A

Syllabus content

A descriptive outline and summary of the topics that will be covered during the module are as follows.  

 

Atmospheric chemistry 

  • Structure and composition of the atmosphere. 

  • Photochemical processes; photochemistry of the stratosphere and the ozone layer. 

  • Chemistry and metereology of the Antarctic ozone hole. 

  • Chemistry and photochemistry of the troposphere and inorganic pollutants, including photochemical smog and acid rain. 

  • Contemporary issues associated with greenhouse gases and global warming, and latest research approaches to reduce emission and mitigate climate change. 

 

The lithosphere 

  • Structures of minerals, silicates, and aluminosilicates; weathering/erosion chemistry of rocks and minerals. 

  • Physical and chemical properties of soils; humic substances; cation exchange capacity; reactions with acids and bases. 

  • Salt-affected (salinated) soils; soil erosion and contamination; threats to healthy soils. 

  • Ethical and sustainability issues associated with healthy soil preservation and soil protection as forms to combat the Climate Emergency. 

 

Chemistry of sea water, fresh water, and properties of the hydrosphere 

  • Hypotheses on the origin of water on Earth; global water cycle and water distribution on the planet. 

  • Ethical considerations of natural water bodies conservation and protection of clean and drinkable water sources. 

  • Chemical composition of sea water; conservative and non-conservative properties; salinity. 

  • Physical properties of water and fundamentals of H bonding. 

  • Chemical properties of water; including solvation and coordination; pH and buffers; redox properties. 

  • Speciation of chemicals in water; pH and redox-dependent speciation and Pourbaix diagrams. 

  • Chemical pollution of natural waters; eutrophication; water purification and desalination of sea water. 

 

General across the course 

  • Key principles of communication for undertaking effective presentations. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience for progressing successfully to Year 2 and above. 

 

The above represent the mandatory content of the module and it is completely covered during the in-person lectures delivered by the module lecturers. In addition, we will provide you with the opportunity to choose areas and topics related to environmental chemistry, sustainability, pollution, to develop yourself and present during the group presentations. 


CH5101: Foundations of Physical Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5101
External Subject Code 101050
Number of Credits 20
Level L4
Language of Delivery English
Module Leader Dr Thomas Slater
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

The aim of this module is to present the essential physical background needed to explain key concepts in physical chemistry. This year 1 module provides a key foundation which will be key for the rest of the programme, in both core physical modules and in many optional modules, later in the degree 

The material in this module includes the essential mathematical treatments and machinery required to understand the key concepts in this field of chemistry. 

The module aims to provide you with an understanding of how properties and events at the atomic level lead to changes and processes at the macroscopic level. 

On completion of the module a student should be able to

By the end of this module, you will be able to... 

 

  • Explain the concepts of molecularity and order of a reaction, the effect of concentration and temperature on reactions, and relate these to reaction mechanisms and energy barriers. 

  • Explain the ways that electromagnetic radiation may interact with molecules to yield spectroscopic transitions, and the regions of the electromagnetic spectrum in which these may be observed. 

  • Explain the properties of gases based on ideal and non-ideal behaviour and the kinetic behaviour of constituent molecules. 

  • Demonstrate knowledge of fundamental concepts in chemical thermodynamics, including enthalpy, entropy, free energy and equilibrium constants and their inter-relations. 

  • Appreciate and explain the properties of ionic solutions in ideal and non-ideal cases, and those of electrochemical cells. 

  • Explain the interaction of X-rays with crystalline solids, interpret the resulting diffraction patterns, and describe the band structure of major classes of material.

How the module will be delivered

A blend of on-line learning activities with face-to-face small group learning support and feedback. 

40 x 1-hour lectures, 4 x 1-hour tutorials and 4 x 1-hour workshops. 

Lectures will deliver the core course content, addressing all learning outcomes.

Formative workshops and tutorials will selectively address learning outcomes, with emphasis on problem solving and forging links between topics. 

Skills that will be practised and developed

Intellectual skills: 

 

  • Ability to link formal theory with the observed behaviour of molecules, solids, and radiation. 

  

Chemistry-specific skills: 

 

  • Interpretation of experimental observations in terms of the molecular properties of the system; 

  • Use of measurements of quantities such as heat, composition, and pressure to determine thermodynamic parameters, and to construct simple phase diagrams; 

  • Use of integrated rate equations, initial rates, and half-lives to determine reaction order, activation energy and pre-exponential factor from experimental data; 

  • Interpretation of electronic, vibrational, and rotational spectra; 

  • Obtaining information on molecular properties such as bond length and bond strength from spectroscopic measurements; 

 

Employability skills: 

 

This module is delivered and aligns with the following University Graduate Attributes: 

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 

Graduate Attributes – Assessment: 

 

Coursework    20%  

 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgement in evaluating sources of information. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems 

 

Exam 80%  

 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgement in evaluating sources of information. 

 

 

Sustainable Development Goals:  

 

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

    

Goal 7. Ensure access to affordable, reliable, sustainable, and modern energy for all.

How the module will be assessed

Small-group tutorials will provide formative feedback, allowing you the chance to assess your competence. Formative workshops will be used to enhance this process. Coursework will provide 20% of the credit and will allow you the chance to assess their progress and calibrate your performance.  A final exam at the end provides the bulk (80%) of the summative assessment. 

  

Tutorials and formative workshops will train you in problem solving associated with the syllabus, and incorporate material being taught at the time. 

  

The coursework will address learning outcomes 1–3, with the end of module exam addressing all the learning outcomes. 

 

Both elements of summative assessment – the examination and the class test – consist of a variety of questions which test a candidate’s knowledge and understanding of concepts, and their ability to deploy those concepts on unseen problems. The portfolio of question parts is constructed so that some parts can be answered with a basic level of knowledge and understanding, and other parts support the demonstration of deeper understanding and capability. The overall balance of these aspects is designed such that candidates can demonstrate satisfaction of the learning outcomes at a basic level and receive the pass mark. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Coursework N/A
Exam - Spring Semester 80 Foundations of Physical Chemistry 2

Syllabus content

Spectroscopy: nature of light (wavelength, frequency, and wavenumber). Atomic spectroscopy: electronic spectrum of H atom. Molecular spectra: vibrational spectroscopy, harmonic oscillators and anharmonicity effects, classification of molecules in rotational spectra (symmetric tops, spherical tops, asymmetric tops), Raman effect. Electronic transitions: photo-electron spectroscopy, absorption spectroscopy, Beer-Lambert law. Electron paramagnetic and nuclear magnetic resonance spectroscopies.  

 

Chemical Kinetics: experimental aspects, rate of reactions, rate laws and rate constants, determining the rate law of a reaction, integrated rate laws, half-life of a reaction, method of initial rates, temperature dependence of reaction rates  

Properties of Gases: ideal gas, mixtures of ideal gases, real gases, equations of state, intermolecular forces, properties of gases at the molecular level, kinetic theory of gases, distribution of molecular speeds. 

 

Thermodynamics: open/closed/isolated systems; state functions; sample and molar quantities. Energy: internal energy, work, heat and the first law; heat capacity; enthalpy; standard states. Entropy: spontaneity, disorder and the second law; third law; variation of entropy with temperature; Gibbs free energy; chemical potential; equilibrium. Mixtures: variation of free energy, chemical potential, and equilibrium constants with composition. 

 

Electrochemistry: Gibbs free energy and electrical work for reversible cells; Gibbs-Helmholtz equation; solutions and solubility products; activity, ionic strength, Debye-Hückel limiting law; Redox potentials, electrochemical potentials, Nernst Equation. 

 

Solid state physical chemistry: X-ray diffraction, Bragg's Law, Miller indices and lattice planes, powder X-ray diffraction. 

 


CH5102: Foundations of Inorganic Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5102
External Subject Code 101043
Number of Credits 20
Level L4
Language of Delivery English
Module Leader Dr Jonathan Rourke
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module starts with a description of atomic structure from a quantum mechanical point of view and introduces electron energy levels (atomic orbitals) from that viewpoint. 

This leads to through to the background to the periodic table, its structure, and its use. Trends in elemental properties are reviewed. 

Simple models of bonding in small molecules are developed and then expanded to include metal complexes.

Crystal field theory is introduced, and the discussion broadened to include ligand field theory, leading to a basic understanding of the splitting of the energies of d-orbitals. 

The common crystal forms, including close packing descriptions of metallic and ionic solid-state structures are introduced.

Lattice energies of ionic solids and Born-Haber cycles, radius ratio rule, Madelung constants and the Kapustinskii equation are covered, as is the relationship between lattice enthalpy and solubility and stability of ionic solids.  

On completion of the module a student should be able to

  • Appreciate the nature of atomic structure, work out electronic configurations and understand the origins of trends within the periodic table.  

  • Derive MO diagrams for homonuclear diatomics (s- and p-block) and use them to predict basic properties.  

  • Be aware of and explain the fundamentals of ligand-metal interactions and hence the thermodynamic stability of complexes.  

  • Outline the use of crystal field theory.  

  • Visualise 3-dimensional aspects of shape and structure and establish the geometries of metals and ions in solids. 

  • Appreciate and identify the nature of lattice enthalpies, and the use of Born-Haber cycles in the calculation of lattice, solvation, and formation enthalpies. 

How the module will be delivered

40 x 1-hour lectures, 6 x 1-hour tutorials and 4 x 1-hour workshops.  

  

Lectures will deliver the core course content, addressing all learning outcomes. Face-to-face lectures will offer the opportunity to engage and interact with material as delivered. Lectures will combine core theory and worked examples relevant to the material delivered, allowing you to understand fully, the expectations for the module.  

 

Formative workshops and tutorials will selectively address learning outcomes, with an emphasis on problem solving and learning outcomes 2,4,6–8. They will provide you with an invaluable opportunity to discuss in detail the course content and fully understand any points that you may have been unsure of.  

Skills that will be practised and developed

Academic Skills: 

 

  • Apply theoretical frameworks to observed properties.  

  • Extrapolate from the fundamental principles and examples given in lectures to related but unseen examples.  

 

 Chemistry-Specific Skills: 

 

  • Construct MO diagrams for both simple diatomic molecules as well as metal complexes.  

  • Derive the properties of complexes and molecules from an understanding of electronic structure.  

  • Use simple models of atomic level packing to predict solid-state properties.  

 

Employability skills:     

   

This module is delivered and aligns with the following University Graduate Attributes: 

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

   

 

Graduate Attributes – Assessment:   

 

Coursework      20%  

 

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Exam      80%  

 

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 

Sustainable Development Goals:    

 

This module is delivered and aligns in working towards the following Sustainable Development Goals:  

 

Goal 6. Ensure availability and sustainable management of water and sanitation for all  

Goal 7. Ensure access to affordable, reliable, sustainable, and modern energy for all  

 

How the module will be assessed

Tutorials throughout the module (3 in each semester) will provide formative feedback, allowing you the chance to assess your competence. Formative workshops will be used to enhance this process.  

 

Coursework will provide 20% of the credit and allow you the chance to assess your progress and calibrate your performance. A final exam at the end of the module provides the bulk (80%) of the summative assessment.  

 

Tutorials and formative workshops will train you in problem solving associated with the syllabus, and incorporate material being taught at the time.  

 

The coursework will address learning outcomes 1-4, with the end of module exam addressing all the learning outcomes. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

  

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.  

  

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session.  

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Coursework N/A
Exam - Spring Semester 80 Foundations of Inorganic Chemistry 2

Syllabus content

All aspects are compulsory  

 

Atomic and molecular structure  

Electronic structure of the atom (qualitative treatment of wavefunctions, hydrogenic atomic orbitals, quantum numbers, many electron atoms, Aufbau principle, Hund’s rules, the Pauli principle, energies of orbitals in many-electron atoms – described in terms of effective nuclear charge, penetration and shielding).  

 

Chemical bonding: covalent vs. ionic vs. metallic bonding vs. H-bonding; Lewis structures, resonance, valence bond theory and its limitations.  Hypervalency.  

MO theory: bonding and antibonding orbitals, energy level diagrams of H2 and 1st row diatomics (homo- and heteronuclear). 

  

Introductory periodicity and main group chemistry  

 

The periodic table (link to atomic structure)  

 

Ionisation energy, electron affinity, electronegativity, atomic and ionic radii  

 

Periodic trends in chemical and physical properties of the elements  

 

Bond energies and non-metal chemistry  

 

Lewis acids and Lewis bases (link to coordination chemistry) 

  

Prediction of molecular structure by VSEPR  

 

Chemistry of the s-block elements (Groups 1 & 2): systematic survey; trends based on increasing size and mass; liquid ammonia, crowns and cryptands (link to coordination chemistry)  

 

Introduction to the transition elements and coordination chemistry  

 

Transition element chemistry  

 

Electronic configurations of neutral atoms; dn configurations of cations (and atoms in molecules)  

 

Variation of thermodynamically most stable oxidation state with conditions (cf. main group metals)  

 

Solution equilibria and electrode potentials; ΔG = −nFE; use of electrode potentials to estimate relative stability of oxidation states (Latimer diagrams), outcome of redox reactions; disproportionation  

 

Trends in oxidation state stability across the series and down the groups  

 

Redox equations  

 

Coordination chemistry  

 

The coordinate bond  

 

Nomenclature  

 

Coordination numbers and geometries; isomerism  

 

Classification of ligands: anionic, bidentate, chelates; s- and p-bonding  

 

Stability constants: chelate and macrocyclic effect; Irving-Williams series  

 

HSAB classification  

 

Crystal Field Theory  

 

Crystal field splitting for an octahedral complex, Δo the crystal field splitting parameter  

 

Crystal field splitting for a tetrahedral ML4 complex, Δt  

 

High/low-spin e-configurations, spin-only magnetic moment  

 

Spectroscopic consequences of d-orbital splitting: empirical treatment of factors affecting Δ; spectrochemical series  

 

Thermodynamic consequences of d-orbital splitting: contribution of crystal field stabilisation energy to lattice energy, hydration energy, stability constants, etc.  

 

Structural consequences of d-orbital splitting: ionic radii  

 

Ligand field theory, MO description of simple complexes, pi acceptor and donor ligands, trans influence, and effect  

 

Structure of Simple Solids  

 

Close packing descriptions of metallic and ionic solid-state structures.  

Radius ratio rule.  

 

The ionic model: lattice energies and the Born-Landé and Kapustinskii equations; use in calculations of other thermodynamic parameters, e.g. electron affinity; thermal stability of carbonates & nitrates  

The solubility of ionic salts and the hydration energies of ions  

 

Lattice energies and Born-Haber cycles  

 

Madelung energy and Kapustinskii equation  

 

Crystal Structure prediction based on electrostatic models  

 

Relationship between lattice energy and solubility  


CH5103: Foundations of Organic Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5103
External Subject Code 100422
Number of Credits 20
Level L4
Language of Delivery English
Module Leader Dr Mark Elliott
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module provides you with the foundation of knowledge required to be able to understand the chemical behaviour of organic molecules and their relevance to biological systems. 

It deals with the structure, shape, and reactivity of organic compounds towards different classes of reagent. 

General principles are used to identify systematic patterns of reactivity and the influence of structure on the properties of compounds.

On completion of the module a student should be able to

  • Demonstrate awareness of the methods and conventions used to describe the shapes and bonding in organic molecules. 2. 

  • Describe reaction mechanisms in terms of the overall change (substitution, elimination, addition), electron-availability and curly arrow convention. 

  • Describe the general characteristics and reactivity of a range of saturated and unsaturated organic compounds. 

  • Relate structure and stereochemistry to reactivity for a broad range of organic chemical reactions. 

  • Predict the outcome and mechanistic course of a reaction by analysis of substrate structure and reaction conditions. 

  • Plan the synthesis of simple structures based on the reactions covered in the syllabus content. 

How the module will be delivered

Face to face lectures, workshop sessions and tutorials will be used for learning support and feedback.

32 x 1 h lectures, 4 x 1-hour formative workshops, 4 x 1-hour formative tutorials.

Lectures will deliver the core course content, addressing all learning outcomes.

Formative workshops and tutorials will selectively address learning outcomes, with an emphasis on problem solving and learning outcomes 4–6.

Skills that will be practised and developed

 

Academic Skills: 

 

  • Extrapolate from the fundamental principles and examples given in lectures to related but unseen examples. 

 

Chemistry-Specific Skills: 

 

  • Understand and use the conventions for representation of molecular structures. 

 

  • Name structures, including the use of stereochemical descriptors. 

 

  • Apply the fundamentals of organic chemistry to a range of situations, including some extension to previously unseen cases. 

 

  • Draw mechanisms for organic reactions covered within the syllabus. 

 

  • Plan an organic synthesis, to choose appropriate strategies, reagents and reaction conditions for the chemistry covered at this level. 

 

  • Link theory and experimental practice in synthetic procedures. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:  

   

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

  

 

Graduate Attributes – Assessment:    

 

Coursework 20%  

 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

 

Exam 80%  

 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Actively reflect on own studies achievements and self-identity  

 

 

  

Sustainable Development Goals:     

 

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture  

Goal 3. Ensure healthy lives and promote well-being for all at all ages 

 

Goal 6. Ensure availability and sustainable management of water and sanitation for all 

Goal 12. Ensure sustainable consumption and production patterns  

Goal 15. Protect, restore, and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss.

How the module will be assessed

Tutorials throughout the module (2 in each semester) will provide formative feedback, allowing you the chance to assess your competence. Formative workshops will be used to enhance this process. Tutorials and formative workshops will train you in problem solving associated with the syllabus, and incorporate material being taught at the time. 

 

Coursework will provide 20% of the credit and will allow you the chance to assess your progress and calibrate your performance. A final exam at the end of the module provides the bulk (80%) of the summative assessment. The coursework will address learning outcomes 1-3, with the end of module exam addressing all the learning outcomes. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session. 

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Coursework N/A
Exam - Spring Semester 80 Foundations of Organic Chemistry 2

Syllabus content

Organic structure, bonding, and reactivity (Autumn semester): 

 

Fundamentals: Structural notations – different representations of organic molecules. Nomenclature of organic compounds. Functional groups, including Nature’s building blocks. Isomers. Electronegativity and bond polarisation. Double-bond equivalents. Bonding in organic compounds – bond lengths, angles, and strengths. Hybridization and molecular orbital theories of bonding. Oxidation levels in organic chemistry. 

 

Shape and Stereochemistry: Conformations of alkanes. Newman projections. Conformation of cyclohexanes, cyclopentanes, including some fused systems. Structure and isomerism of alkenes. Classification of isomers (constitutional, configurational, enantiomers, diastereoisomers). Cahn-Ingold-Prelog rules (R/S stereochemical descriptors). Stereochemical representations of organic compounds (flying wedge and Newman projections). Strategies for separation of enantiomers. 

 

Bonding and Reactive Intermediates: Conjugation and resonance. Delocalisation of π-electrons – resonance and representation of resonance. Definition of aromaticity. Molecular orbitals for ethene, butadiene. Hyperconjugation. Shape, structure, and stability of carbocations, carbanions and free radicals. Acids and Bases: pH, pKa (making connection with carbanions). 

 

NMR Spectroscopy: Introduction to chemical shift, integration and coupling patterns in the context of NMR spectroscopy. 

 

Describing Organic Reactions: Homolytic vs heterolytic bond breaking; bond dissociation energy; enthalpy and DH; entropy and DS; Gibbs free energy and DH; equilibria; thermodynamics vs kinetics; rate laws; activation energy (Ea), the Arrhenius equation; free energy diagrams; intermediates and transition states; the Hammond postulate; nucleophiles and electrophiles; use of curly arrow to represent electron movement; curly arrows for nucleophilic attack / substitution, loss of a leaving group / elimination, proton transfers and carbocation rearrangements. 

 

Substitution reactions: SN1 and SN2: rate laws; free energy diagrams; curly arrow pushing mechanism; molecular orbital analysis; intermediates and transition states; regioselectivity; stereoselectivity; factors that determine mechanism (substrate, nucleophile, solvent and leaving group). Synthetic analysis and strategy – how to predict which type of substitution mechanism will dominate under a given set of conditions. 

 

Elimination reactions: E1, E1cB and E2; rate laws; free energy diagrams; curly arrow pushing mechanisms; molecular orbital analysis; intermediates and transition states; regioselectivity; stereoselectivity; factors that 

 

determine mechanism (substrate, nucleophile, solvent and leaving group); Synthetic analysis and strategy – how to predict which type of elimination mechanism will dominate under a given set of conditions. 

 

Introduction to functional group chemistry (Spring semester): 

 

Alkene Chemistry 1: Addition of HX to alkenes. Bromination of alkenes, including stereochemical and regiochemical consequences. Simple hydration of alkenes. Examples including cyclohexenes. Epoxidation of alkenes. Consequences of conjugation, including UV-vis spectroscopy. 

 

Alkyne chemistry 1: Addition to alkynes – halogenation, reduction, simple hydration. Formation and reaction of acetylide anions. 

 

Aromatic Chemistry 1: Molecular orbitals of benzene. Electrophilic substitution (nitration, bromination, sulfonation, Friedel-Crafts), following from alkene addition, highlighting the mechanistic similarities. Regiochemical outcome of reactions, relating to the common theme of carbocation stability and resonance. 

 

Carbonyl chemistry 1: Types of carbonyl group, oxidation level and structure, bonding, and infrared spectroscopy. Oxidative synthesis of aldehydes, ketones, and carboxylic acids. Addition reactions to aldehydes and ketones, including Bürgi-Dunitz trajectory, molecular orbital analysis, and formation of stereocentres (racemates). Formation and addition of Grignard and organolithium reagents. Formation of acetals, ketals,imines,imines, and enamines. Hemi-acetals and relationship to sugars. Formation and hydrolysis of carboxylic esters and of amides. Enzymatic hydrolysis of esters and amides. Hydride reduction of aldehydes, ketones, esters, and amides. NADH as Nature’s hydride, highlighting aromaticity as driving force, and relevance to typical biological reaction conditions. The reduction of aldehydes and ketones to alkanes: Wolff-Kishner reaction. 

 

Carbonyl chemistry 2: Enols, enolates and pKa. Typical reactivity and molecular orbital analysis. Aldol and Claisen condensations. Redox disproportionation of non-enolizable aldehydes. 


CH5108: Introduction to University Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5108
External Subject Code 100417
Number of Credits 10
Level L4
Language of Delivery English
Module Leader Dr Jonathan Rourke
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This Module aims to excite and enthuse you in the field of Chemistry, while gently introducing you to university life. 

It will form the first two weeks of the first year and serves as aco transition from school style teaching and acts as a prelude to the more formal teaching that follows.  

This Module provides an introduction to some of the fundamental skills, learning resources and techniques students need for their future study. 

Laboratory work will be introduced, and safety aspects and skills will be developed. With a heavy emphasis on teamwork the Module will foster a sense of community and belonging, enhancing student engagement and commitment.  

On completion of the module a student should be able to

  • Understand the legal aspects of safety in the laboratory environment   

  • Make a basic safety assessment of laboratory work/ chemical hazards     

  • Present scientific data in an appropriate form, with uncertainties and errors recorded correctly   

  • Develop Maths skills: basic algebra; density/yields/moles/purity calcs; Sig figs, Units (micro, nano etc) and converting between   

  • Appreciate and demonstrate how to make accurate notes and to begin to think about structuring essays/reports and how to reference within the essay/report.  

  • Present information as part of a group to a large audience. 

How the module will be delivered

A blend of large group learning activities with face-to-face small group learning support and feedback.  

The module will be delivered through a combination of lectures, tutorials, practical lab sessions, group exercises, individual assignments, and whole class presentations.  

Skills that will be practised and developed

Intellectual Skills: 

  • Locate physical and on-line resources for study at Cardiff University.  

  • Navigate the Cardiff Campus and locate all key teaching and social spaces.   

  • Use Learning Central and SIMS to access key information.   

  • Use the library and online resources to access subject specific information  

  • Operate IR and UV/vis spectrometers and record simple spectra. 

  • Assemble and use laboratory glassware correctly 

 

 Chemistry-Specific Skills: 

  • Retrieve, record, and structure chemical information from different sources (lectures, on-line, library).   

  • Safely perform basic laboratory operations in chemistry.   

 

Employability skills:     

This module is delivered and aligns with the following University Graduate Attributes:     

   

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Understand organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

   

  

Graduate Attributes – Assessment:    

Class Test            33%

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate, and present with impact. 

  • Deliver, accept, and act on constructive feedback.  

  • Consider own personal and professional ethical, social, and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Understand organisations, their stakeholders, and their impact on the community. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Class Test            33% 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate, and present with impact. 

  • Deliver, accept, and act on constructive feedback.  

  • Consider own personal and professional ethical, social, and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Understand organisations, their stakeholders, and their impact on the community. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Report                 34%

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate, and present with impact. 

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted. 

  • Consider own personal and professional ethical, social, and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Actively reflect on own studies achievements and self-identity 

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 4. Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all 

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, and decent work for all 

Goal 13. Take urgent action to combat climate change and its impacts 

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development 

 

 

How the module will be assessed

Formative assessment for the module will be provided via recapping feedback sessions from the module leader and personal tutors.  Peer feedback discussions will enhance your self-awareness. 

Summative assessment will be provided through two multiple choice computer-based assessments (learning outcomes 1–2 and 4), a lab report (learning outcomes 3–5) and a final group presentation (learning outcome 6) covering all aspects of what you think you have learnt.   

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.  

Reassessment will be in form similar to the original assessment.  

Assessment Breakdown

Type % Title Duration(hrs)
Class Test 33 Safety in the University Laboratory N/A
Class Test 33 Algebra, numbers, errors and uncertainties N/A
Report 34 Laboratory report N/A

Syllabus content

Introduction to Cardiff   

Student support   

Students’ Union   

ITS   

Sports   

Halls   

Library   

Food/drink   

Careers service   

Societies (ChemSoc)   

 

Personal and professional development   

Journey through the degree. Differences BSc/MChem (mark requirements), Placements   

Personal tutor (who will explain Ex Circs)   

Communicating with staff and students (email too)   

Being part of an International Scientific Community (breadth of learning)   

  

Practical Chemistry   

Safety – PPE, correct clothing, COSHH   

Simple glassware assembly (reflux, distillation, filtration)   

Choosing glassware of appropriate scale.   

Weighing, measuring volumes (making up a standard solution)   

Critical reading of script (not blind following)   

Reproducibility of measurements (leading to errors)   

Run IR, UV/vis, spectra   

 

Maths   

Basic algebra   

Density/yields/moles/purity calculations.   Significant figures   

Units (micro, nano etc) and converting between 

   

Study Skills   

What a lab/lecture/tutorial/workshop is (and expectations of time commitment)   

notetaking/note making (and the difference between the two)   

lab notes and reports   

LC/Sims/Turnitin/submission of work   

Panopto   

Time management   

IT resources (Office, Chemdraw)   

Exams/past papers/adjustments   

Use of the Library to retrieve information (books only at this stage   

 

Assessment/Standards/Feedback   

Expectations of staff   

Module evaluation   

Staff/Student Panel   

 


CH5110: Year 1 Chemistry Foundation Practical

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5110
External Subject Code 100417
Number of Credits 30
Level L4
Language of Delivery English
Module Leader Dr Guto Rhys
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

Laboratory chemistry is central to a thorough appreciation for the subject as a whole. 

This module delivers practical and interpretation skills spanning the whole range of chemistry.

Experiments covering the areas of organic, biological, inorganic, physical, analytical chemistry and spectroscopy will be carried out. 

The experimental outputs (samples, datasets, spectra) will be interpreted and analysed. Experimental results will be linked with the appropriate theory and mechanism to deliver a coherent and holistic view of the subject.

Various pre-lab activities, including some teaching of spectroscopy and chromatography, will support the in-lab and related activities.

There will be an emphasis on safety and correct working practice. 

On completion of the module a student should be able to

  • Understand the function of, and safely use, a broad range of laboratory equipment and chemicals. 

  • Access and understand risk assessment documents, and handle chemicals and equipment following the safe handling instructions. 

  • Undertake a range of synthetic chemistry transformations and physical chemistry investigations that are directly relevant to the material covered in taught modules at this level. 

  • Recognise the fundamental link between experiment and theory in the development of chemistry. 

  • Interpret experimental data and hence determine the outcome of a particular experiment. 

  • Present the results of experimental work in a structured and rigorous manner, showing a clear appreciation of the context of the work. 

How the module will be delivered

Prior to each laboratory session, students will be required to engage with online resources to fully prepare them to undertake the practical work and to demonstrate an appreciation of safety.

Students will carry out a structured series of experiments, working closely with experienced demonstrators who will be responsible for the supervision and assessment/feedback on the experiment.

During each experiment, discussion and feedback will be provided so that students can develop and practice key skills relating to the understanding and interpretation of experimental data.

Content that is closely allied with experimental work, specifically spectroscopy and chromatography, will be delivered to further cement the link between experiment and theory. 

Skills that will be practised and developed

Academic Skills: 

 

  • You will learn how to assess the risks associated with the use of chemicals and laboratory apparatus. At this level, risk assessment documents will be prepared by academic staff and provided. 

  • Use a theoretical model of a physical system to interpret experimental data. 

 

Chemistry-Specific Skills: 

 

  • You will learn and practise basic techniques that are used across the breadth of the experimental chemistry curriculum. 

  • You will carry out experimental work in synthetic chemistry, preparing chemicals that are then purified using common procedures. 

  • You will assess the purity of compounds you have prepared using a range of analytical and spectroscopic methods. 

  • You will use various scientific instruments to measure and monitor chemical reactions and properties. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.   

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

  

Graduate Attributes – Assessment:    

  

Written Assessment                     40% 

 

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities. 

  • Deliver, accept, and act on constructive feedback.  

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Practical Skills Assessment         60% 

 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities. 

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience. 

  • Communicate complex ideas effectively to diverse audiences. 

  • Deliver, accept, and act on constructive feedback.  

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 6. Ensure availability and sustainable management of water and sanitation for all  

Goal 7. Ensure access to affordable, reliable, sustainable, and modern energy for all 

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

Goal 13. Take urgent action to combat climate change and its impacts  

Goal 14. Conserve and sustainably use the oceans, seas, and marine resources for sustainable development 

Goal 15. Protect, restore, and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss  

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development 

How the module will be assessed

Formative feedback will be delivered on all aspects during the laboratory sessions by academic supervisors and demonstrators. The overall quality of working and output will contribute to the ‘Lab Work’ component of assessment.

At two points in the module, students will submit a scientific report, as part of a portfolio of assessment, covering one synthetic chemistry and one instrumental chemistry experiment. Experiments will be written up in a style designed to develop professional standards of reporting. Each of these portfolios will be summatively assessed, with feedback on the first portfolio able to be used to improve the second portfolio.

Students are required to pass each individual component of this module. All assessments will contribute to the delivery of all learning outcomes. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided the student has sufficient credit in relation to the resit rule adopted by their programme. If the amount of credit gained by the student is less than permitted by the relevant resit rule, the student may be permitted to repeat study if they are within the threshold set for the Repeat rule adopted by your programme. The student will be notified of their eligibility to resit/repeat any modules after the Examining Board in the Summer period.

Students who do not pass the ‘Practical Work’ component of this module will be required to resit as an internal student during the next academic session.

Students who do not pass one or more of the ‘Portfolio’ components will be provided with a resit opportunity over the summer following the academic session. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Report 1000 Autumn Synthetic Report N/A
Report 1000 Autumn Intrumental Report N/A
Report 1000 Spring Synthetic Report N/A
Report 1000 Spring Instrumental Report N/A
Laboratory Work 375 Synthesis 1 N/A
Laboratory Work 375 Synthesis 2 N/A
Laboratory Work 375 Synthesis 3 N/A
Laboratory Work 375 Synthesis 4 N/A
Laboratory Work 375 Synthesis 5 N/A
Laboratory Work 375 Synthesis 6 N/A
Laboratory Work 375 Synthesis 7 N/A
Laboratory Work 375 Instrumental 1 N/A
Laboratory Work 375 Instrumental 2 N/A
Laboratory Work 375 Instrumental 3 N/A
Laboratory Work 375 Instrumental 4 N/A
Laboratory Work 375 Instrumental 5 N/A
Laboratory Work 375 Instrumental 6 N/A
Laboratory Work 375 Instrumental 7 N/A
Laboratory Work 375 Instrumental 8 N/A
Laboratory Work 375 Programming 1 N/A

Syllabus content

All aspects are mandatory.

Introductory skills covering techniques such as setting up glassware for experiments and associated procedures such as recrystallisation, distillation, accurate measurement of instrumental data.

Preparation, purification, and characterization of a range of organic and inorganic compounds (e.g. amides, esters, transition metal compounds, interhalogen compounds).

Interpretation of spectroscopic data (UV, IR, NMR) relating both to compounds prepared and to more general interpretation.

Acquisition of data, including choosing conditions and settings; collection and accurate recording of data. 

Understanding of the term's “accuracy” and “precision.”

Reporting of and dealing with errors in the analysis of data.

Using theoretical models of physical systems to interpret data.  


CH5116: Mathematical Methods for Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5116
External Subject Code 100403
Number of Credits 10
Level L4
Language of Delivery English
Module Leader Dr Colan Hughes
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

The aim of this module is to provide you with an understanding of the mathematical techniques underpinning the chemistry degree course. 

It will enable you to follow the application of these techniques within other modules and to use these techniques where required. 

On completion of the module a student should be able to

  • Use trigonometric, exponential and log functions, including algebraic manipulations and apply the sine and cosine rules. 

  • Differentiate and integrate common functions. 

  • Use vectors and matrices, including the use of matrices to transform vectors, and should understand the principles of eigenvectors and eigenvalues. 

  • Utilise the principle of complex numbers, should be able to perform algebra involving complex numbers, find complex roots to quadratic equations and use Argand diagrams. 

  • Apply the principles of probability, including the use of the binomial distribution. 

  • Use the statistical applications of the normal distribution, including the central limit theorem and confidence intervals. 

How the module will be delivered

10 × recorded 1-hour lectures with exercises, 10 × 1 hour in-person problem classes.  

Additional online exercises will be made available. 

Revision session before the exam. 

Skills that will be practised and developed

The use of programming as an aid to understanding and using mathematics will be demonstrated in some of the classes. 

 

This module will develop independent and critical thinking skills, allowing you to solve problems in any field you may enter after graduation. 

 

 Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:  

  

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Understand organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

   

Graduate Attributes – Assessment:    

 

Coursework              20% 

 

  • Deliver, accept, and act on constructive feedback.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Written Exam           80% 

 

  • Deliver, accept, and act on constructive feedback.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Resit Coursework       20% 

 

  • Deliver, accept, and act on constructive feedback.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Resit Exam              80%  

 

  • Deliver, accept, and act on constructive feedback.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  

Sustainable Development Goals:     

  

This module does not align with any of the Sustainable Development Goals, but its topics obviously underpins all efforts.  

How the module will be assessed

Formative feedback will be provided for all the problem classes, through both marking of the submitted work and addressing difficulties during the classes. Emphasis in the feedback will be placed on how the questions covered in the classes relate to the class test and exam. 

The module is assessed via coursework (20%) and a final exam (80%). 

The summative coursework will assess the learning outcomes from the first semester and will allow the students to assess their progress. The final exam will assess all the learning outcomes. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Coursework N/A
Exam - Spring Semester 80 Mathematical Methods for Chemistry 2

Syllabus content

Functions: Trigonometric, exponentials and logs. 

Calculus: Basic principles, differentiation and integration of functions, rules for differentiation, integration by parts and by substitution, partial differentiation. 

Coordinate systems: Two- and three-dimensional Cartesian, polar and spherical. 

Vectors and matrices: Lengths and angles, matrix transformation, eigenvectors, and eigenvalues. 

Complex numbers: Principle, algebra, solutions to quadratic equations, Argand diagrams. 

Probability: Expected values, the binomial distribution 


CH5130: Introduction to Drug Development

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5130
External Subject Code 100420
Number of Credits 10
Level L4
Language of Delivery English
Module Leader Dr Fabrizio Pertusati
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module gives an overview of the process of drug development from selection of therapeutic area through to use of a drug in patients. 

The different stages of the pharmaceutical pipeline will be explored, including the challenges faced at each one and strategies for overcoming these, with consideration given to scientific, technical, financial, and legal hurdles. 

You will become familiar with pharmaceutical industry terminology used to refer to different aspects of drug development, the diverse skills necessary to bring a product to market, and the employment opportunities available in the pharmaceutical industry.  

On completion of the module a student should be able to

  • Give examples of different types of therapeutic area and associated drugs.   

  • Describe the stages of development of a new drug.   

  • Outline the stakeholders in drug development and the interactions between them.   

  • Analyse and present the challenges that could be encountered during development of a drug and strategies that have been employed to overcome these. 

How the module will be delivered

The module will be delivered through 16 x 1-hour lectures and 2 x 2-hour formative workshops and one summative workshop. 

You will have the opportunity to research an aspect of drug development and careers in pharmaceuticals and to present your findings. 

The workshops will provide a forum for you to explore and discuss the opportunities and challenges in bringing a new drug to the clinic.   

Skills that will be practised and developed

 

Chemistry Specific Skills:  

 

  • Identify the areas of chemistry and other sciences that are applied throughout drug development.   

 

  • Identify job roles and career pathways for chemistry graduates within drug development.   

 

 

Academic Skills: 

 

  • Balancing multiple potentially conflicting requirements and views of different stakeholders in a drug development project.   

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:  

 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Understand organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Graduate Attributes – Assessment:    

 

Coursework           100% 

 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities. 

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience. 

  • Listen to and take account of the views of others. 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate and present with impact. 

  • Deliver, accept and act on constructive feedback.  

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Understand organisations, their stakeholders and their impact on the community. 

  • Actively take responsibility for promoting human rights, celebrating diversity and widening inclusion 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Understanding organisations, their stakeholders and their impact on the economy 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 3. Ensure healthy lives and promote well-being for all at all ages.

 

How the module will be assessed

Formative assessment: Workshops will provide the opportunity for formative feedback through presentation and discussions with staff and peers.   

 

Summative assessment: The summative coursework will provide an opportunity to demonstrate knowledge and understanding of the syllabus content and to research and analyse an aspect of drug development and to present these findings in written form.  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:   

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Coursework N/A

Syllabus content

Mandatory content   

 

  • Types of drug and therapeutic areas.   

  • History of drugs and drug development.   

  • Role of different stakeholders in pharmaceuticals – patients, healthcare providers, regulatory agencies, investors, insurance companies, companies (pharmaceutical, biotechnology, contract research, manufacturing, and services), academic researchers.   

  • The processes involved at key stages of drug discovery, and the associated terminology will be introduced (therapeutic area, drug targets, medicinal chemistry, QSAR, patenting, hits and leads, ADMET, formulation, manufacturing, ethics, clinical trials, regulatory approval).   

  • Interdisciplinarity of pharmaceutical research and the interplay between chemistry, biochemistry, physiology, and pharmacology.   

  • Career opportunities in pharmaceuticals – types of employers, job roles and skills required.   

 

Optional content   

 

  • You will have the opportunity to research a topic of your own choice in drug development.    


CH5150: Introduction to Green and Sustainable Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5150
External Subject Code 101045
Number of Credits 10
Level L4
Language of Delivery English
Module Leader Dr Sankar Meenakshisundaram
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module introduces the challenges associated with greenhouse gas emissions, air pollution, waste generation, plastic contamination, fossil-fuel based feedstock and sustainability. 

This module further introduces the difference between linear economy and circular economy and the necessity to transform from the current linear society to a circular society. 

After introducing the challenges, this module discusses the principles of green chemistry, metrics to assess the greenness of chemical and fuel production processes, life-cycle analysis, role of chemistry and catalysis in addressing the above-mentioned global grand challenges. 

Finally, you will be introduced to the current developments in the sustainable production of chemicals and fuels from renewable feedstock such as waste biomass and CO2. 

Emerging novel greener alternatives to conventional chemical synthesis methodologies will also be discussed.  

On completion of the module a student should be able to

  • Appreciate and explain the challenges such as climate change, environmental pollution, CO2 emission, waste generation.  

  • Identify specific challenges associated with using conventional fossil-fuel based feedstock for producing chemicals and energy.  

  • Define and calculate the key metrics such as E-factor and Atom Economy used in green chemistry and apply the metrics to identify sustainable synthetic routes.  

  • Appreciate the importance of catalytic processes compared to reactions using stoichiometric reagents and identify sustainable feedstocks and sustainable methods for the routes.   

  • Appreciate the difference between linear economy and circular economy.  

How the module will be delivered

The module content will be delivered via face-to-face activities including lectures, discussion, and workshops. 

Lecture materials will be recorded and provided to support your independent learning. 

The material will also be supported by formative self-assessment tests introduced at regular points in the delivery schedule. 

The module will consist of 24 hours lecture, workshop and worked examples. 

Another 3 hours of group presentation as a continuous assessment. 

The week-by-week delivery schedule and timing of summative and formative tasks will be described in the module map. 

Skills that will be practised and developed

Academic skills:  

 

  • You will develop skills to critically analyse examples from the scientific literature and encouraged to collaborate with your peers in analysing and reviewing case studies.  

 

  • The summative assessment (group assessment) will allow for collaborative working when researching and critically analysing literature data enabling discussion of ideas between peers. 

 

  •  These discussions will focus on the scientific reasoning required to develop a commercial process to produce chemicals and fuels.  

 

Chemistry-Specific Skills: 

 

  • You will have the opportunity to develop your independent critical analysis and problem-solving skills, dealing with data from a variety of methods to a rounded understanding of sustainable and renewable feedstock, quantification of waste, circular economy, and green energy.  

 

  • The module is centred in sustainable chemistry, and you will also acquire the vocabulary and analytical skills to exercise critical judgement regarding the contribution a particular catalytic process can make to improving the environment and reducing the impact of anthropogenic activity.  

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:  

 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Understand organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Graduate Attributes – Assessment:    

  

Coursework           100% 

 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities. 

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience. 

  • Listen to and take account of the views of others. 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate and present with impact. 

  • Deliver, accept and act on constructive feedback.  

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Understand organisations, their stakeholders and their impact on the community. 

  • Actively take responsibility for promoting human rights, celebrating diversity and widening inclusion 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Understanding organisations, their stakeholders and their impact on the economy 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture 

Goal 6. Ensure availability and sustainable management of water and sanitation for all  

Goal 7. Ensure access to affordable, reliable, sustainable, and modern energy for all  

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, and decent work for all  

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

Goal 11. Make cities and human settlements inclusive, safe, resilient, and sustainable  

Goal 12. Ensure sustainable consumption and production patterns  

Goal 13. Take urgent action to combat climate change and its impacts  

Goal 14. Conserve and sustainably use the oceans, seas, and marine resources for sustainable development  

Goal 15. Protect, restore, and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss.

How the module will be assessed

Summative assessment will consist of a group problem solving exercise, using the methods taught in this module, and a group presentation of the solution. The marking scheme will assess your understanding of the material in the literature sources and your ability to critically assess the way that a process conforms to the concepts of Green Chemistry.  

 

Marking criteria is provided as a separate document on the Learning Central. Feedback and marks on this presentation will be given immediately after the presentation session.  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the summer period.  

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session. 

Assessment Breakdown

Type % Title Duration(hrs)
Presentation 100 Group Presentation N/A

Syllabus content

Lectures  

Introduction to Green Chemistry and concepts of Sustainability. Source of environmental contamination including greenhouse gases and solid and liquid pollutants. Carbon capture and utilisation. 

Society’s demands on chemicals and energy. Current and alternative sources of energy. Energy storage, batteries, and hydrogen economy.  

Biomass and circular economy. Concept of zero waste.  

Introduction to life cycle analysis and sustainability. Measure of sustainability including the concepts on E-factor and atom economy.  

Introduction to homogeneous, heterogeneous, and enzymatic catalysis and how catalytic processes are environmentally benign compared to reactions involving stoichiometric reagents.  

 

Assignment  

 

In this, you will be given an opportunity to choose a real-world problem, relevant to green and sustainable future, analyse the problems and come with a possible solution for this problem. 

The solution will be presented to your peers along with the staff members. 

This gives you an opportunity in problem solving, teamwork and communication skills. 


CH5153: Cemeg Organig Sylfaenol

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5153
External Subject Code 100422
Number of Credits 20
Level L4
Language of Delivery Welsh
Module Leader Dr Heulyn Jones
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

Mae'r modiwl hwn yn rhoi'r sylfaen wybodaeth sydd ei hangen ar ddysgwyr i allu deall ymddygiad cemegol moleciwlau organig a'u perthnasedd i systemau biolegol. 

Mae'n delio ag adeiledd a siâp cyfansoddion organig, a’u hadweithedd â gwahanol ddosbarthiadau o adweithyddion. 

Defnyddir egwyddorion cyffredinol i nodi patrymau systematig mewn adweithedd a’r dylanwad y mae adeiledd cyfansoddion yn ei gael ar eu priodweddau. 

On completion of the module a student should be able to

  • Dangos ymwybyddiaeth o'r dulliau a'r confensiynau a ddefnyddir i ddisgrifio siapiau moleciwlau organig a'r bondiau ynddynt. 2. 

  • Disgrifio mecanweithiau adweithiau yn nhermau’r newid cyffredinol (amnewid, dileu, ychwanegu), argaeledd electronau a’r confensiwn saethau cyrliog. 

  • Disgrifio nodweddion cyffredinol ac adweithedd ystod o gyfansoddion organig dirlawn ac annirlawn. 

  • Cysylltu strwythur a stereocemeg ag adweithedd ar gyfer ystod eang o adweithiau cemegol organig. 

  • Rhagweld canlyniad a thrywydd mecanistig adwaith drwy ddadansoddi strwythur y swbstrad ac amodau’r adwaith. 

  • Cynllunio synthesis strwythurau syml ar sail yr adweithiau yr ymdrinnir â hwy yng nghynnwys y maes llafur. 

How the module will be delivered

Defnyddir darlithoedd wyneb yn wyneb, sesiynau gweithdy a thiwtorialau ar gyfer cymorth dysgu ac adborth. 

  

32 x darlith 1 awr, 4 x gweithdy ffurfiannol 1 awr, 4 x tiwtorial ffurfiannol 1 awr. 

Bydd darlithoedd yn cyflwyno cynnwys craidd y cwrs, gan ymdrin â'r holl ganlyniadau dysgu. 

  

Bydd gweithdai ffurfiannol a thiwtorialau yn ymdrin â deilliannau dysgu yn ddetholus, gyda phwyslais ar ddatrys problemau a deilliannau dysgu 4–6. 

Skills that will be practised and developed

Sgiliau Academaidd: 

 

  • Allosod o'r egwyddorion sylfaenol a'r enghreifftiau a roddir mewn darlithoedd i enghreifftiau cysylltiedig ond rhai nas gwelwyd o’r blaen. 

 

Sgiliau sy’n benodol i gemeg:  

 

  • Deall a defnyddio'r confensiynau ar gyfer cynrychioli adeileddau moleciwlaidd. 

 

  • Enwi adeileddau, gan gynnwys defnyddio disgrifyddion stereocemegol. 

 

  • Cymhwyso hanfodion cemeg organig i ystod o sefyllfaoedd, gan gynnwys eu hestyn rywfaint i achosion nas gwelwyd o'r blaen. 

 

  • Llunio diagramau o fecanweithiau ar gyfer adweithiau organig y mae’r maes llafur yn eu cwmpasu. 

 

  • Cynllunio synthesis organig, gan ddewis strategaethau, adweithyddion ac amodau adwaith priodol ar gyfer y gemeg sydd wedi’i chwmpasu ar y lefel hon. 

 

  • Cysylltu damcaniaethau ag ymarfer arbrofol mewn gweithdrefnau synthetig. 

 

Sgiliau cyflogadwyedd:    

  

Cyflwynir y modiwl hwn ac mae'n cyd-fynd â'r Rhinweddau Graddedigion Prifysgol canlynol:  

   

  • Cyfrannu at drafodaethau, negodi, a chyflwyno’n effeithiol.  

  • Ystyried eu cyfrifoldebau moesegol, cymdeithasol ac amgylcheddol personol a phroffesiynol.  

  • Dangos gonestrwydd, dibynadwyedd a gallu personol a phroffesiynol.  

  • Cofio am yr argyfwng hinsawdd a nodau datblygu cynaliadwy’r Cenhedloedd Unedig  

  • Nodi, diffinio a dadansoddi materion a syniadau cymhleth, gan arfer barn feirniadol wrth werthuso ffynonellau gwybodaeth.  

  • Arddangos chwilfrydedd deallusol a cheisio meithrin gwybodaeth a dealltwriaeth. 

  • Ymchwilio i broblemau a chynnig datrysiadau effeithiol, myfyrio a dysgu o lwyddiannau a methiannau.  

  • Creu syniadau gwreiddiol a chymhwyso ffyrdd creadigol, llawn dychymyg a dyfeisgar o feddwl wrth ymateb i anghenion a phroblemau a nodwyd.  

  • Mynd ati’n bwrpasol i fyfyrio ar eu hastudiaethau eu hun, eu cyflawniadau a’u hunaniaeth.  

  • Dangos gwydnwch, hyblygrwydd a chreadigrwydd i ddelio â heriau, a bod yn agored i newid.  

  • Adnabod a chyfleu eu sgiliau, eu gwybodaeth a’u dealltwriaeth eu hunain yn hyderus ac mewn amrywiaeth o gyd-destunau.  

  • Ystyried syniadau, cyfleoedd a thechnolegau newydd, gan adeiladu ar wybodaeth a phrofiad i wneud penderfyniadau gwybodus am eu dyfodol eu hunain. 

  

 

Rhinweddau Graddedigion – Asesiad:    

 

Gwaith cwrs 20%  

 

  • Ymchwilio i broblemau a chynnig datrysiadau effeithiol, myfyrio a dysgu o lwyddiannau a methiannau.  

  • Creu syniadau gwreiddiol a chymhwyso ffyrdd creadigol, llawn dychymyg a dyfeisgar o feddwl wrth ymateb i anghenion a phroblemau a nodwyd. 

 

Arholiad 80%  

 

  • Ymchwilio i broblemau a chynnig datrysiadau effeithiol, myfyrio a dysgu o lwyddiannau a methiannau.  

  • Creu syniadau gwreiddiol a chymhwyso ffyrdd creadigol, llawn dychymyg a dyfeisgar o feddwl wrth ymateb i anghenion a phroblemau a nodwyd. 

  • Mynd ati’n bwrpasol i fyfyrio ar eu hastudiaethau eu hun, eu cyflawniadau a’u hunaniaeth.  

 

 

  

Nodau Datblygu Cynaliadwy:     

 

Cyflwynir y modiwl hwn mewn modd sy'n cyd-fynd â gweithio tuag at y nodau datblygu cynaliadwy canlynol:   

 

Nod 2. Rhoi diwedd ar newyn, sicrhau diogelwch bwyd a gwell maeth, a hyrwyddo amaethyddiaeth gynaliadwy  

Nod 3. Sicrhau bywydau iach a hyrwyddo lles i bawb o bob oedran

Nod 6. Sicrhau argaeledd a rheolaeth gynaliadwy o ddŵr a glanweithdra i bawb 

Nod 12. Sicrhau patrymau defnydd a chynhyrchu cynaliadwy  

Nod 15. Amddiffyn, adfer a hyrwyddo defnydd cynaliadwy o ecosystemau daearol, rheoli coedwigoedd yn gynaliadwy, mynd i’r afael â diffeithdiro, ac atal a gwyrdroi diraddiad tir ac atal colli bioamrywiaeth 

 

How the module will be assessed

Bydd tiwtorialau a gynhelir drwy gydol y modiwl (dau ym mhob semester) yn darparu adborth ffurfiannol, gan roi cyfle i fyfyrwyr asesu eu cymhwysedd. Defnyddir gweithdai ffurfiannol i gyfoethogi’r broses hon. Bydd sesiynau tiwtorial a gweithdai ffurfiannol yn hyfforddi myfyrwyr i ddatrys problemau sy'n gysylltiedig â'r maes llafur, ac yn ymgorffori deunydd sy'n cael ei ddysgu ar y pryd. 

 

Bydd gwaith cwrs yn darparu 20% o'r credyd ac yn rhoi cyfle i fyfyrwyr asesu eu cynnydd a graddnodi eu perfformiad. Bydd arholiad terfynol ar ddiwedd y modiwl yn darparu'r rhan fwyaf (80%) o'r asesiad crynodol. Bydd y gwaith cwrs yn mynd i'r afael â deilliannau dysgu 1-3, gyda'r arholiad diwedd y modiwl yn mynd i'r afael â'r holl ddeilliannau dysgu. 

 

Y CYFLE AR GYFER AILASESIAD YN Y MODIWL HWN: 

 

Dim ond ar y ddealltwriaeth nad ydych wedi methu mwy o gredydau nag a nodir yn y rheol ailsefyll a fabwysiadwyd gan eich rhaglen y caniateir cyfleoedd ar gyfer ailasesiad. Os yw swm y credydau yr ydych wedi’u methu yn fwy na'r hyn a ganiateir gan y rheol ailsefyll berthnasol, mae’n bosibl y cewch ganiatâd i ail-wneud eich astudiaethau os ydych o fewn y trothwy a osodwyd ar gyfer y rheol Ail-wneud a fabwysiadwyd gan eich rhaglen. Byddwch yn cael gwybod a ydych yn gymwys i ailsefyll/ailwneud unrhyw fodiwlau ar ôl cyfarfod y Bwrdd Arholi yn ystod cyfnod yr haf. 

 

Cynhelir asesiadau pob modiwl sy’n cael ei ailsefyll yn y cyfnod Ailsefyll Arholiadau, sef cyn dechrau’r sesiwn academaidd ddilynol. 

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Cemeg organig sylfaenol - Gwaith Cwrs N/A
Exam - Spring Semester 80 Cemeg Organig Sylfaenol 2

Syllabus content

Adeiledd organig, bondio ac adweithedd (semester yr hydref): 

 

Hanfodion: Nodiannau strwythurol — cynrychioliadau gwahanol o foleciwlau organig. Dull enwi cyfansoddion organig. Grwpiau gweithredol, gan gynnwys blociau adeiladu’r byd natur. Isomerau. Electronegatifedd a pholareiddio bondiau. Cyflyrau cyfwerth â bond dwbl. Bondiau mewn cyfansoddion organig – hyd, onglau a chryfderau bondiau. Hybrideiddio a damcaniaethau orbitalau moleciwlaidd mewn perthynas â bondiau. Lefelau ocsidiad mewn cemeg organig. 

 

Siâp a stereocemeg: Cydffurfiadau alcanau. Cynrychioliadau Newman. Cydffurfiad cylchohecsanau a cylchopentanau, gan gynnwys nifer o systemau asiedig. Strwythur ac isomeredd alcenau. Dosbarthiad isomerau (adeileddol, ffurfweddiadol, enantiomerau, diastereoisomerau). Rheolau Cahn-Ingold-Prelog (disgrifyddion stereocemegol R/S). Cynrychioliadau stereocemegol o gyfansoddion organig (lletem hedfan a chynrychioliadau Newman). Strategaethau ar gyfer gwahanu enantiomerau. 

 

Bondiau a rhyngolynnau adweithiol: Cyfunedd a chyseiniant. Datleoliad electronau electronau-π – cyseiniant a chynrychioli cyseiniant. Diffinio aromatigedd. Orbitalau moleciwlaidd ar gyfer ethen a bwtadeuen. Gorgyfunedd. Siâp, adeiledd a sefydlogrwydd carbocatïonau, carbanionau a radicalau rhydd. Asidau a basau: pH, pKa (gwneud cysylltiad â charbanionau). 

 

Sbectrosgopeg NMR: Cyflwyniad i batrymau sifft cemegol, integreiddiad a chyplu yng nghyd-destun sbectrosgopeg NMR. 

 

Disgrifio Adweithiau Organig: Cymharu torri bondiau drwy fecanwaith homolytig a mecanwaith heterolytig; egni daduno bond; enthalpi a dH; entropi a dS; egni rhydd Gibbs a dH; ecwilibria; cymharu thermodynameg a chineteg; deddfau cyfradd; egni actifadu (Ea) a hafaliad Arrhenius; diagramau egni rhydd; rhyngolynnau a chyflyrau trosiannol; cynosodiad Hammond; niwcleoffilau ac electroffilau; defnyddio saethau cyrliog i gynrychioli symudiad electronau; saethau cyrliog ar gyfer ymosodiad / amnewidiad niwcleoffilig, colli grŵp ymadael / dileu, trosglwyddiadau protonau ac ad-drefniadau carbocatïonau. 

 

Adweithiau amnewid: SN1 ac SN2: deddfau cyfradd; diagramau egni rhydd; mecanwaith gwthio â saethau cyrliog; dadansoddiad o orbitalau moleciwlaidd; rhyngolynnau a chyflyrau trosiannol; regioddetholedd; stereoddetholedd; ffactorau sy'n pennu’r mecanwaith (swbstrad, niwcleoffil, hydoddydd a grŵp gadael). Dadansoddiad a strategaeth synthetig – sut i ragweld pa fath o fecanwaith amnewid fydd flaenaf o dan set benodol o amodau. 

 

Adweithiau dileu: E1, E1cB ac E2; deddfau cyfraddau; diagramau egni rhydd; mecanweithiau gwthio â saethau cyrliog; dadansoddiad o orbitalau moleciwlaidd; rhyngolynnau a chyflyrau trosiannol; regioddetholedd; stereoddetholedd; ffactorau sy'n 

 

pennu’r mecanwaith (swbstrad, niwcleoffil, hydoddydd a grŵp gadael). Dadansoddiad a strategaeth synthetig – sut i ragweld pa fath o fecanwaith dileu fydd flaenaf o dan set benodol o amodau. 

 

Cyflwyniad i gemeg grwpiau gweithredol (semester y gwanwyn) 

 

Cemeg alcenau 1: Ychwanegiadau HX at alcenau. Bromineiddio alcenau, gan gynnwys canlyniadau stereocemegol a regiocemegol. Dull syml o hydradu alcenau. Enghreifftiau’n cynnwys cylchohecsanau. Epocsideiddio alcenau. Canlyniadau cyfunedd, gan gynnwys sbectrosgopeg UV-gweladwy. 

 

Cemeg alcynau 1: Ychwanegiadau at alcynau – halogeniad, rhydwytho, hydradiad syml. Ffurfio anionau asetylid a’u hadweithiau. 

 

Cemeg Aromatig 1: Orbitalau moleciwlaidd bensen. Amnewid electroffilig (nitradu, bromineiddio, sylffonadu, Friedel-Crafts) o ganlyniad i ychwanegu alcen, gan bwysleisio’r tebygrwydd yn y mecanwaith. Canlyniadau regiocemegol adweithiau, sy'n ymwneud â’r thema gyffredin sefydlogrwydd a chyseiniant carbocationau. 

 

Cemeg carbonyl 1: Mathau o grwpiau carbonyl, lefel ocsidiad ac adeiledd, bondiau, a sbectrosgopeg is-goch. Synthesis ocsidiol aldehydau, cetonau ac asidau carbocsylig. Adweithiau ychwanegu at aldehydau a cetonau, gan gynnwys taflwybr Bürgi-Dunitz, dadansoddiad o orbitalau moleciwlaidd a ffurfio stereoganolion (racemadau). Ffurfio ac ychwanegu adweithyddion Grignard ac organolithiwm. Ffurfio asetalau, cetelau, iminau ac enaminau. Hemi-asetalau a’u perthynas â siwgrau. Ffurfio esterau carbocsylig ac amidau a’u hydrolysis. Hydrolysis ensymatig esterau ac amidau. Rhydwythiad hydrid aldehydau, cetonau, esterau ac amidau. NADH fel hydrid y byd natur, gan dynnu sylw at aromatigedd fel y prif rym ysgogi, a pherthnasedd i amodau adweithiau biolegol arferol. Rhydwytho aldehydau a cetonau i alcanau: adwaith Wolff-Kishner. 

 

Cemeg carbonyl 2: Enolau, enoladau a pKa. Adweithedd arferol a dadansoddiad o orbitalau moleciwlaidd. Adweithiau cyddwyso aldol a Claisen. Dadgyfraniad rhydocs o aldehydau nad ydynt yn enolisadwy. 


CH8117: Environmental Chemistry (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8117
External Subject Code 101045
Number of Credits 10
Level L4
Language of Delivery English
Module Leader Dr Andrea Folli
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module discusses the chemistry of the environment, including the atmosphere, hydrosphere and lithosphere. Particular attention is devoted to the causes and effects of pollution in the environment, such as smog, acid rain, global warming, ozone depletion, water pollution, and the methods used for pollution control.  Furthermore, the physical and chemical properties of water and soils are examined in detail, with particular emphasis on their environmental impact.

On completion of the module a student should be able to

describe the physical properties of the atmosphere and the differences in chemical composition of various layers;

describe the photochemistry of stratosphere;

describe ozone chemistry and the Chapman cycle;

discuss the of meteorology of the Antarctic ozone hole;

describe inorganic pollutants of the troposphere, with reference to climate change;

discuss case studies associated with photochemical smog and acid rain;

describe chemical emissions from volcanoes, and related sulfur chemistry;

describe the Miller-Urey experiment and discuss it in the context of volcanic emissions;

describe the global water cycle and the chemical composition of sea water;

discuss and compare conservative and non-conservative properties of sea water;

describe the interaction of the atmosphere with sea water and discuss its consequences;

describe the properties of the hydrosphere;

describe the properties of the lithosphere;

describe the physical properties of solis used for classification;

discuss how the chemical properties of soils can be influenced by atmospheric conditions;

explain the key chemical and physical threats to soil that have a negative environmental impact;

plan, conduct and report on an individual research assignment;

present a critical argument through a written piece of work;

plan and present a group presentation on a chosen environment-related subject.

How the module will be delivered

16 x 1h lectures, 5 x 2h workshops

Skills that will be practised and developed

Chemistry-specific skills

On completion of this module student will be able to:

  1. apply an understanding of radical chemistry to the photochemistry of atmosphere;
  2. apply an understanding of radical chemistry to elucidation of the anthropogenic pollution of the troposphere;
  3. apply of knowledge of solution chemistry to understanding the chemical composition and physical properties of sea and fresh water.

Transferable skills

This module will also:

  1. introduce and develop the use of web-based resources;
  2. develop skills in the critical analysis of data;
  3. develop essay-writing skills;
  4. develop experience of group work and presentational skills.

How the module will be assessed

The module is summatively assessed via in course assessments.

There is no examination for this module.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Environmental Chemistry (Study Abroad) N/A

Syllabus content

Atmospheric chemistry

Structure and composition of the atmosphere; photochemical processes; photochemistry of the stratosphere and the ozone layer; chemistry and metereology of the Antarctic ozone hole; chemistry and photochemistry of the troposphere and inorganic pollutants; photochemical smog; acid rain; global warming.

Chemistry of volcanoes

Volcanic emissions; sulfur chemistry; Miller-Urey experiment - the origins of life?

Chemistry of sea-water

Global water cycle; chemical composition of sea-water; conservative and non-conservative properties; salinity; interaction with atmosphere: gases in sea-water.

The hydrosphere

Physical and chemical properties of water; gases in water; redox properties; buffers, pH; effect of dissolved carbonate and carbon dioxide; pollution of natural waters; eutrophication; water purification.

The lithosphere

Structures of minerals; silicates and aluminosilicates; weathering/erosion chemistry of rocks and minerals; physical and chemical properties of soils; humic substances; cation exchange capacity; reactions with acids and bases; salt-affected (salinated) solis; soil erosion and contamination.


CH3299: Organic Chemistry for Visiting or Exchange Students

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH3299
External Subject Code 100422
Number of Credits 10
Level L5
Language of Delivery English
Module Leader Dr Yi-Lin Wu
Semester Spring Semester
Academic Year 2025/6

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Coursework N/A

CH5201: Further Physical Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5201
External Subject Code 101050
Number of Credits 20
Level L5
Language of Delivery English
Module Leader Professor David Willock
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module builds on the concepts introduced in CH5101, Foundations of Physical Chemistry. In Further Physical Chemistry you will meet new material in the topics of Symmetry and Group Theory, Quantum Mechanics, Spectroscopy, Thermodynamics, Soft matter, and Chemical Kinetics. 

 

Symmetry and Group Theory covers the ideas of symmetry elements and operations used to quantify molecular shape into point groups. You will learn how to use a basis to analyse molecular vibrational modes using character tables with examples showing how this helps understand the selection rules for IR and Raman spectra. This will allow you to use spectra to classify geometric isomers. 

 

Quantum Mechanics will discuss the quantum nature of electrons including wave-particle duality, postulates of QM, the uncertainty principle. After introduction of the Schrödinger equation model Hamiltonians examples will be used to show how boundary conditions lead to quantisation and energy levels. Extension to many electron atoms will consider electronic Coulombic and exchange interactions, spin-orbit coupling, the Russell-Saunders scheme, and term symbols. The topic will also introduce the Pauli principle and look at applications in atomic spectra. 

 

Spectroscopy is concerned with the interaction of electromagnetic radiation with matter. In this topic the focus will be on commonly used laboratory scale spectroscopy using microwave, infra-red and visible light. You will cover the origin of the spectroscopic effects including selection rules. 

 

In thermodynamics the relationships between equilibrium, free energy and chemical potential will be introduced. You will consider the importance of thermodynamic relations in the description of the thermodynamics of gases, liquids, solids, and interfaces. You will also discover the statistical basis of thermodynamics and work with model systems to understand how the collective behaviour of molecules results in the bulk properties of chemical systems. 

 

Soft matter includes an introduction to colloids, surfactants, micelles, microemulsions and particle suspensions. You will learn how to apply thermodynamic concepts to understand the interaction of surfactants with liquids and the phases that can be formed. 

 

Chemical kinetics will be concerned with rate equations for complex reactions, steady-state, and equilibrium approximations; enzyme kinetics; chain reactions. Polymerisation, photochemistry, and non-linear systems will also be discussed. The importance of surface kinetics in understanding adsorption and desorption from solid surfaces will also be covered and used to understand data from experimental temperature programmed desorption results in conjunction with X-ray photoelectron spectroscopy (XPS) characterisation. 

On completion of the module a student should be able to

  • Apply symmetry and group theory to solving problems relating to both bonding and spectroscopy 

  • Use the concepts of quantum mechanics to explain the role of quantisation in chemical and spectroscopic phenomena.  

  • Predict spectroscopic properties of atoms and molecules  

  • Develop the statistical basis of thermodynamics enabling the student to be familiar with key concepts of entropy, mixing in ideal mixtures of fluids and Boltzmann distribution/factors.    

  • Apply thermodynamic concepts to soft matter to explain how physical interactions lead to the stability, flocculation, or precipitation of colloidal particle dispersions.  

  • Use chemical kinetics to analyse data from reactions taking place at interfaces including adsorption, desorption, and reaction on surfaces.  

How the module will be delivered

The module content will be delivered via face-to-face activities supported by on-line video content showing further detail and examples of ideas introduced in lectures. The material will also be supported by formative self- assessment tests introduced at regular points in the delivery schedule. 

The module will consist of 43 x 1-hour lectures and 6 x 1-hour tutorials divided evenly between topics.

The tutorial format will be small group discussion.

In this dual semester module, three topics will be delivered in the first semester and three in the second with topics delivered sequentially. 

The week-by-week delivery schedule and timing of formative tasks will be described in the module map.  

Skills that will be practised and developed

Academic Skills:  

 

This module will enable you to:   

 

  • Appreciate the use of mathematical descriptions of simplified models to understand the behaviour of complex systems.  

  • Better understand the application of logical thinking to practical problems including mapping a problem onto abstract concepts.  

  • Gain insight into physical systems based on statistical analysis.  

 

 
Chemistry-Specific Skills:  

 

This module will develop your subject specific skills across important areas of Physical Chemistry. You will: 

  • Learn and apply the concepts of group theory to predict the vibrational spectroscopy from molecular structure.  

  • Describe theoretical treatment of wave properties of matter within the quantum mechanical approach.  

  • Appreciate how solutions of the Schrödinger equation are found for model systems and recognise the physical and chemical significance of these solutions.  

  • Explore the statistical basis of thermodynamics working with model systems to understand macroscopic phenomena.  

  • Apply prior learning of fundamental thermodynamics to simple colloidal systems.  

  • Show an ability to use rate equations to describe chemical reaction rates in solution and on surfaces.  

 

Employability skills:     

   

This module is delivered and aligns with the following University Graduate Attributes:     

   

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

  

   

Graduate Attributes – Assessment:     

   

Coursework                 20%  

 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

 

Exam                            80%  

 

  • Communicate complex ideas effectively to diverse audiences. 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

 

 

Sustainable Development Goals:      

   

This module is delivered and aligns in working towards the following Sustainable Development Goals:    

  

  • Goal 6. Ensure availability and sustainable management of water and sanitation for all 

  • Goal 7. Ensure access to affordable, reliable, sustainable and modern energy for all 

  • Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

How the module will be assessed

Formative assessments will include:  

Topic specific self-assessment exercises introduced alongside lecture material. Formative assessment will allow you to monitor your own understanding of the topics studied as they development. Solutions and feedback on the self-assessment exercises will be provided and reviewed during lectures so that you can self-mark your attempts.  

 

Full engagement with the self-assessment exercises will build confidence with the material delivered and prepare you for the summative assessment components of the module.  

 

Summative assessment will consist of Coursework, covering topics delivered in the Autumn semester and an end of year exam covering all module content.  

 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.  

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session. 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Coursework N/A
Exam - Spring Semester 80 Further Physical Chemistry 3

Syllabus content

 

The module is based around six key topics in Physical Chemistry which are used to develop your understanding of the use of important concepts to quantitatively analyse chemical data.  

 

  1. Symmetry will be introduced using a range of examples to illustrate the symmetry elements and operations used to classify molecules into point groups. The identification of equivalent operations will also be discussed to help understand the sets of unique operations defined for point groups. The idea of operations as matrices will then be used to introduce characters and character tables. Group theory ideas of reducible representations and the reduction formula follow with an emphasis on the analysis of molecular vibrations. This will lead to the mathematical basis of selection rules with applications in rotational, IR, and Raman spectroscopy.  

 

  1. Quantum Mechanics is concerned with the wave properties of matter: kinetic and potential energy, wave-particle duality, postulates of QM, Schrödinger equation, uncertainty principle. Applications of Schrödinger equation will emphasize the importance of boundary conditions and include particle in a box, barrier tunnelling, the harmonic oscillator. We will also consider orbital motion and angular momentum in the hydrogen atom, leading to hydrogen like orbitals. Extensions of basic theory will include many electron atoms (He), the Pauli principle and Hund’s rules, showing how this can be used to understand the structure of the periodic table. Electronic atomic spectra will be used to exemplify electronic wave functions, Coulombic interaction and term symbols, exchange and spin-orbit interactions, Russell-Saunders coupling and j-j coupling.  

 

  1. Spectroscopy will cover the concepts underlying a range of techniques. Microwave spectra probe molecular rotational motion and so requires understanding of the rotational energy levels of molecules in terms of their moments of inertia and angular momenta. The cases of diatomic molecules, rigid and non-rigid rotors will be introduced. For infra-red spectroscopy molecular normal modes of vibration are the important molecular property. The role of anharmonic motion on relative energy levels, and the resulting allowed transitions, including fundamental and overtone transitions, are introduced. The mixing of vibrations and rotations leads to vibration-rotation spectra with P, Q, R branches, of IR spectroscopy. Visible and UV spectra arise from electronic transitions requiring concepts such as the Born-Oppenheimer approximation, electronic states, Franck-Condon factors, dissociation energies, and the model of Birge-Sponer extrapolation. Electronic transitions to/from excited states are described through the Jablonski diagram with reference to energy transfer and the role of quenching in excited state lifetimes.  

 

  1. Thermodynamics will begin with a reprise of classical thermodynamics, including 1st and 2nd laws, Gibbs energy and equilibrium. Thermodynamics of mixing within and beyond the ideal model. The molecular basis of thermodynamics will then be discussed leading to the Boltzmann distribution. Examples such as simple estimates of equilibrium constants from the Boltzmann distribution will be used to illustrate its importance. This will then be extended to a statistical understanding of Internal energy and heat capacity at low and high temperatures. Dulong and Petit’s law. Heat capacities of gases. Gibbs free energy of formation, extensivity and partial molar quantities, solubility products. 

 

  1. Soft matter will cover an introduction to colloids, surfactants, micelles, microemulsions and particle suspensions. The use of thermodynamics to understand their properties will be illustrated through the effect of surfactants on surface tension; thermodynamic models of micellisation and critical micelle concentration. This will lead into the free energy change for micellisation; liquid/liquid and solid/liquid dispersions, free energy changes and qualitative understanding through molecular interaction energies and potential energy diagrams.  

 

  1. Kinetics will consider steady-state and equilibrium approximations; enzyme kinetics; chain reactions and polymerisation. The importance of surface kinetics in understanding adsorption and desorption from solid surfaces will also be covered and used to understand data from experimental temperature programmed desorption results in conjunction with X-ray photoelectron spectroscopy (XPS) characterisation. 


CH5202: Structure, bonding and reactivity in compounds of the p and d-block elements

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5202
External Subject Code 100417
Number of Credits 20
Level L5
Language of Delivery English
Module Leader Professor Ian Fallis
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module builds on the knowledge, understanding and skills acquired by successful completion of the Year 1 module CH5102, to explore further the chemistry of main group and transition elements. 

Trends in the behaviour of the p-block elements and their compounds are considered, with particular focus on the inert pair effect, the role of d-orbitals, p-bonding, and structure and bonding in main group and “electron-deficient’ compounds.  

The mechanisms of substitution and redox reactions of transition metal complexes are described. Trends in reactivity and magnetic properties are explained in terms of ligand field theory. 

You will develop a formal understanding of bonding in transition metal complexes, as a platform for identifying the spectroscopy and reactivity of such complexes. 

You will develop a systematic knowledge of organometallic chemistry, and thereby explore some of the conceptual links between organic and inorganic chemistry. 

On completion of the module a student should be able to

  • Rationalise trends in chemical properties within/across groups in terms of electronic and atomic properties and identify characteristic structural building blocks of extended structures 

  • Evaluate the roles of π-bonding, inert pair effect, and variations in overlap and bond strength in influencing properties and predict the structures and properties of yet unseen cluster molecules based on electron counting; 

  • Derive – in ligand field terms – orbital energy diagrams of tetrahedral and square planar complexes and use these to interpret both magnetic properties and their UV/vis absorption spectra 

  • Derive and interpret MO diagrams for octahedral complexes and related organometallics and u this as the for understanding the 18e rule  

  • Use an MO bonding description to describe the bonding of common ligands to transition metals. Appreciate synthetic methods to make simple complexes. 

  • Appreciate and predict basic reactivity of transition metal organometallic complexes, exemplified by ligand substitution, oxidative addition, reductive elimination, and migratory insertion reactions. 

 

How the module will be delivered

 

The module content will be delivered via face-to-face activities supported by on-line video content. Material will be supported by formative self-assessment tests at regular points in the delivery schedule, often linked to tutorial content. 

The module will consist of 40 x 1-hour lectures and 6 x 1-hour tutorials and 2 x1-hour tutorials divided appropriately between topics.

The tutorial format will be a small group discussion. 

The week-by-week delivery schedule and timing of formative tasks will be described in the module map. 

Skills that will be practised and developed

Intellectual Skills: 

This module will enable you to: 

  • Apply theoretical frameworks to observed properties 

 

  • Extrapolate from the fundamental principles and examples given in lectures to related but unseen examples 

Chemistry-Specific Skills: 

 

This module will develop your subject specific skills across important areas of Inorganic Chemistry. You will: 

  • Use MO diagrams, with electron counting protocols, to establish both p and d block metal complex structures and suggest likely reaction pathways 

 

  • Use spectroscopic data to elucidate or verify proposed structures 

 

  • Use the electronic structure of a complex to derive the magnetic and spectroscopic properties of metal complexes 

 

  • Use the concepts of sigma donation and pi back bonding to account for the stability of organometallic complexes, and to suggest patterns of reactivity 

 

  • Use quantum mechanical and group theory concepts to develop bonding theory 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

Coursework                    20%  

 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

 

Exam                            80%  

 

  • Communicate complex ideas effectively. 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 7. Ensure access to affordable, reliable, sustainable and modern energy for all 

Goal 8. Promote sustained, inclusive and sustainable economic growth, full and productive employment and decent work for all 

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

 

How the module will be assessed

 

Tutorials throughout the module (3 in each semester) will provide formative feedback, allowing you the chance to assess your competence. Formative workshops will be used to enhance this process. 

Coursework will provide 20% of the credit and allow you the chance to assess your progress and calibrate your performance. A final exam at the end of the module provides the bulk (80%) of the summative assessment. 

Tutorials and formative workshops will train you in problem solving associated with the syllabus, and incorporate material being taught at the time. 

Coursework will address learning outcomes 1–3, with the end of module exam addressing all the learning outcomes. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.  

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session. 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Coursework N/A
Exam - Spring Semester 80 Further Inorganic Chemistry 3

Syllabus content

Main group chemistry 

Ionic versus covalent bonding; role of d-orbitals; π-bonding; structure and bonding; aromaticity. 

Chemistry of the p-block elements (Groups 13-16): systematic survey; ionic vs. covalent; trends in reactivity and structure; borazine, phosphazene and SN rings; multiple bonding between heavier main group elements (disilenes, distannenes, etc) 

Electron-deficient compounds: diborane, Wade’s rules, carboranes, other main group clusters. 

Organometallic chemistry of main group elements (s- & p-block): synthesis, reactivity, structure, and bonding 

Coordination chemistry 

Mechanisms of reactions of metal complexes 

Trends in reaction rates as a function of periodicity. Electronic influences on rates. 

Fundamental mechanistic types – associative, dissociative, interchange. 

Determination of mechanisms, fundamental rate equation, thermodynamic parameters, dependence on pressure, stereochemical studies, labelling studies. 

Other mechanisms – Bailar twist, conjugate base mechanism. 

Ligand influences on reactivity of coordination complexes in aqueous solution: p-base/p-acid ligands. 

Reaction mechanisms in square planar complexes, dual pathway mechanism. 

Trans effect and trans influence. Werner’s studies on square planar complexes. 

Oxidation reduction reactions, inner sphere, and outer sphere mechanisms. 

Principle of microscopic reversibility. 

 

Transition metal spectroscopy 

Revision of term symbols; 

Electronic transitions and ligand field theory; spectrochemical series and ligand type; 

Spectra of Oh vs. Td; 

Jahn-Teller effects; 

Symmetry and Tanabe-Sagano diagrams; 

Orgel diagrams; 

Racah B/C parameters and ligand donor type; 

 

d-Block Organometallic Chemistry 

MO diags for octahedral complexes: sigma and pi bonding. Electron counting, co-ordination compounds vs organometallics. The 18-electron rule and exceptions to it, including 16 electron square planar complexes. 

Bonding of ligands to metal centres. 

Carbon monoxide: sigma donation, pi back bonding, effect on IR spectra 

Phosphines: bonding and steric effects 

Hydrides and dihydrogen: bonding, back bonding, and transformation to dihydride. Recognition that is oxidative addition. 

Organic molecules as ligands, exemplified through systems such as: h1 bonding with alkyls; h2 with alkenes; h3 with allyls; h4 with cyclobutadiene; h5 with cyclopentadienyl; h6 with benzene 

Carbenes: Fischer, Schrock and NHC. Other less common ligands 

Reactions of organometallics 

Ligand substitution exemplified by carbonyl replacement, the differences between 16e and 18e complexes (associative vs dissociative substitution). Masked dissociative pathways. 

Oxidative Addition and Reductive Elimination. 

1,1-Migratory insertion reactions, as exemplified by migration onto carbonyl ligands. 

1,2-Insertions and β-hydride elimination. 

 

Bonding (group theory) 

Quantum mechanics and group theory descriptions of orbitals, and their overlap, leading to the bonding in diatomic and polyatomic molecules; 

Molecular orbital and valence bond theories for small molecules and coordination complexes. 

 


CH5203: Further Organic and Biological Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5203
External Subject Code 100422
Number of Credits 20
Level L5
Language of Delivery English
Module Leader Dr Niklaas Buurma
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module builds on the concepts introduced in year 1 and provides a coherent mechanistic overview of key organic functional groups, including both their synthesis and reactivity. 

After an overview of advanced carbonyl group chemistry, the module delves into the synthesis and reactivity of aromatic, heteroaromatic and heterocyclic compounds––common chemical building blocks for materials with societal importance. 

The final section of the module introduces stereochemical control in organic synthesis, emphasising the significance and control of the three-dimensional arrangements of atoms in molecules. 

 

On completion of the module a student should be able to

  • Recognise and explain the general structure and reactivity of a range of saturated and unsaturated organic compounds, including alkenes, carbonyls, aromatic and heteroaromatic compounds. 

  • Apply the fundamental principles by which a reaction can be chemo-, regio- or stereo-selective, and the energetic basis for selectivity in a range of organic transformations. 

  • Predict and rationalise the outcome of organic reactions using the curly arrow convention for reaction mechanisms. 

  • Deduce the likely mechanisms of unknown but similar reactions using mechanistic reasoning based on known reaction pathways. 

  • Design the synthesis of a stereospecific or heterocyclic compound using material covered in year-1 organic chemistry and the syllabus contents of this module. 

How the module will be delivered

44 x 1-hours lectures + formative workshops, 4 x 1-h tutorials; divided evenly across two semesters. 

Content will be delivered primarily through lectures.

Lectures will be used to provide content related to all learning outcomes. These will be consolidated by tutorial work, which provides tailored feedback to students. 

Formative workshops and feedback will focus on problem-solving, weighted more towards learning outcomes 3–5. 

 

Skills that will be practised and developed

Academic Skills: 

 

  • The formative and summative assessments will refine your ability to communicate and explain complex concepts clearly and objectively, whether orally or in written form. 

 

Subject-specific skills: 

 

  • On completing the module, you will be able to apply logical thinking to the planning of organic synthesis. Specifically, you will be adept at selecting and identifying appropriate strategies, reactants, reagents, and reaction conditions based on the integrated principles learned in years 1 and 2. 

  • You will develop an enhanced appreciation for chemical and biological species as three-dimensional entities, gaining proficiency in recognising how their composition and 3D structure influence reactivity. 

  • In conjunction with the laboratory modules, you will connect theoretical concepts with practical chemistry

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:  

   

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and display an ability use information to a fashion that displays deep appreciation of the facts. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, application of knowledge confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

 Coursework          20% 

 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

 

 Exam                  80% 

 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture  

Goal 3. Ensure healthy lives and promote well-being for all at all ages

Goal 12. Ensure sustainable consumption and production patterns 

Goal 15. Protect, restore, and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss.

How the module will be assessed

Formative Assessment: The assessments provide timely opportunities for you to review and apply principles learned in this module to tackle problem-solving exercises. They take place in the form of in-class workshops and small-group tutorials; feedback will be provided either orally or in written form.  

 

Summative Assessment: Written examination will comprise problems based on the lecture materials that are expanded to include previously unseen molecules and reactions. These assessments let you show that you have mastered the intellectual and module-specific learning outcomes. The marking will be emphasised on the reasonable description of the reactivity of functional groups, the ability to deduce the outcome and mechanism of multi-step synthesis, and the stereochemical control based on the three-dimensional shape of molecules. The January test is an opportunity to receive feedback on your progress towards the learning outcomes. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

Opportunities for reassessment are permitted, provided you have not failed more credit than in the resit rule adopted by their programme. Students permitted by the Examining Board to be reassessed in this module during the same academic session will sit an examination during the Resit Examination Period (approximately in August) before the start of the following academic session. The format of the reassessment will be identical to the original one.  

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Coursework N/A
Exam - Spring Semester 80 Further Organic Chemistry 3

Syllabus content

Autumn Semester  

 

Carbonyl Chemistry 3: Further examples of enols and enolate chemistry: crossed aldol, Knoevenagel and related condensations. Mannich reaction. Dianion chemistry. Kinetic and thermodynamic enolates (as silyl enol ether formation). The Wittig reaction and its variants. Enolate-type chemistry of sulfoxides, sulfones and sulfoximines. Reductive amination reactions. 

 

Alkene Chemistry 2: Hydroboration and epoxidation of alkenes. Ozonolysis of alkenes. Dihydroxylation and oxidative cleavage of diols. 

 

Rearrangements: Carbocation rearrangements. The pinacol and semi-pinacol rearrangement. Migration to electron-deficient nitrogen and oxygen (Baeyer-Villiger, Beckmann, Curtius and related rearrangements – Hofmann, Lossen, Schmidt). 

 

Conjugation: Conjugate addition to alpha, beta-unsaturated carbonyl compounds. Organocuprates and malonate-type nucleophiles (including Robinson-type annulation reactions). Baylis-Hillman reaction.  

 

Aromatic Chemistry 2: Nucleophilic aromatic substitution (SNAr). Diazonium salts (Sandmeyer reactions). Formation and reactivity of benzyne.  

 

 

Spring Semester  

 

Aromatic Heterocycle Reactivity: Difference in basicity and reactivity of pyridine, pyrrole, indoles and imidazoles. Electrophilic substitution in heteroaromatic systems. Nucleophilic substitution of halogenated heteroaromatic systems. C-Metalated heterocycles. 

 

Aromatic Heterocyclic Synthesis: Retrosynthetic analysis and synthesis of aromatic heterocyclic systems – pyridine, pyrimidine, pyrrole, furan, oxazole, thiazole, imidazole, and some of their benzo-fused analogues, with explicit connections to carbonyl chemistry. Non-aromatic heterocycle synthesis using the en(oid) reagents and Diels-Alder strategy. 

 

Ring-forming Reactions: Conformational and orbital effects in ring-forming reactions. 

 

Criteria for stereoselectivity: Definition and types of stereoselectivity. Energy profiles for stereoselective reactions. 

 

Substrate-controlled stereoselective reactions: Reduction of cyclohexanones, epoxidation/cyclopropanation of cyclic allylic alcohols. Cram/Felkin-Anh model for stereoselective addition to carbonyls. Zimmerman-Traxler transition states for diastereoselective aldol reactions. 

 

Reactant- or catalyst-controlled stereoselective reactions: Asymmetric epoxidation, dihydroxylation, hydrogenation, and alkylation. 

 

 


CH5206: Communicating Chemistry: Key skills for chemists

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5206
External Subject Code 100417
Number of Credits 10
Level L5
Language of Delivery English
Module Leader Dr Angelo Amoroso
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module builds on the knowledge, understanding and skills acquired by successful completion of the Year 1 modules CH5108 and CH5110. 

You will have opportunities to enhance your employability, by increasing your expertise in a variety of areas, such as: data retrieval, analysis, and presentation; team working; information technology, and communication. 

The module addresses many of the skills described under the Cardiff Graduate Attributes. 

On completion of the module a student should be able to

  • Locate available sources for retrieval of scientific information and utilise a variety of methods for its extraction and presentation.  

  • Effectively communicate aspects of chemistry to both expert and non-expert audiences (for instance, in an employment interview or a scientific meeting). 

  • Present scientific information in a variety of formats to audiences with a range of scientific literacy. 

  • Collate, analyse, and present a summary of a research area in an essay at a level that would inform a knowledgeable chemist interested in the area. 

  • Work as part of a team to develop a presentation of a research topic. 

How the module will be delivered

11 x 2-hour and 1-hour lecture/workshops.  

These will be a mixture of lecture type presentations and workshop events. 

 

Skills that will be practised and developed

Chemistry-Specific Skills: 

 

  • Use generally applicable software to deliver presentation, create documents, analyse data, and manage literature. 

  • Use of chemistry specific drawing and visualisation software to present diagrammatic data. 

  • Use of chemistry specific databases to retrieve chemical information. 

  • Search electronic sources for technical information exercising critical judgement in evaluating sources of information. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Display a knowledge of organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Graduate Attributes – Assessment:    

  

Poster Presentation             20% 

 

  • Communicate complex ideas effectively to diverse audiences. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Oral Presentation                 30% 

 

  • Communicate complex ideas effectively to diverse audiences. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Actively reflect on own studies achievements and self-identity 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Written Assessment             50% 

 

  • Communicate complex ideas effectively to diverse audiences. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Actively reflect on own studies achievements and self-identity 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

  

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 4. Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all  

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, and decent work for all  

Goal 12. Ensure sustainable consumption and production patterns  

Goal 13. Take urgent action to combat climate change and its impacts

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development 

 

How the module will be assessed

The module is a summative assessment via three tasks: a group poster, a written presentation, and a non-technical oral presentation. All assessments will address all learning outcomes, though at different levels. 

The group work could potentially be moderated in line with personal portfolios of work prepared by each student. 

There will also be a series of tasks during the module which will be used to provide formative feedback. 

Any academic or competence standards which may limit the availability of adjustments or alternative assessments for disabled students should be clearly stated in line with guidance provided in the Reasonable Adjustment Policy and Procedure 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

Assessment Breakdown

Type % Title Duration(hrs)
Presentation 20 Group Poster Presentation N/A
Written Assessment 50 Written Assessment N/A
Presentation 30 Oral Presentation N/A

Syllabus content

  • Career reflection, management, and interview skills (to be taught with assistance from Careers Service). 

  • Database searching for chemistry resources on the internet e.g. Scopus, Web of Knowledge, Sci-finder. 

  • Use of a reference manager program: Correct referencing and acknowledgement; avoidance of plagiarism. 

  • Use of chemical drawing software. 

  • Scientific graphical software 

  • Using critical analysis to choose appropriate topics for presentations (visual, written, and oral). 

  • Translation of complex scientific information and communicating it effectively, taking into account the audience and context. 

  • Verbal and visual presentation skills, to be used in a group poster and a short talk. 

  • Written presentation skills, including the identification and communication of key messages. 

  • Business Model Canvas 


CH5207: Introduction to the chemistry of life

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5207
External Subject Code 100417
Number of Credits 10
Level L5
Language of Delivery English
Module Leader Dr Matthew Tredwell
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module introduces students to carbohydrates, amino acids, and proteins and their role in living organisms. 

An insight to these fundamental molecules of life and their roles will be discussed in the context of their physical properties, shape, and reactivity. 

This module builds on the general principles of organic chemistry that are used to identify patterns of reactivity and how this influences the roles of these molecules. 

On completion of the module a student should be able to

  • Draw the different representations of carbohydrates to identify stereochemical elements and predict reaction outcomes. 

  • Draw the structures of proteinogenic amino acids, di-, and polypeptides at varying pH. 

  • Explain the interactions between amino acids in relation to the different protein structure levels. 

  • Relate structure and reactivity of compounds to their role in the chemistry of life. 

  • Predict curly-arrow mechanisms for biological transformations by applying fundamental principles of organic chemistry. 

  • Solve equations relating to changes in Gibbs free energy  

How the module will be delivered

17 x 1-hour lectures will deliver the core course content, addressing all the learning outcomes.

2 x 1 hour formative workshops, 2 small group tutorials will enhance knowledge of key learning outcomes through problem solving. 

 

Skills that will be practised and developed

Academic skills: 

 

  • You will take part in tutorials during which discussions on the topics raised will enable you to demonstrate your intellectual curiosity and offer potential solutions, allowing you to develop your critical thinking and verbal communication skills. 

  • You will develop skills in critical judgment in evaluating electronic and printed resources around the module topic. 

 

Chemistry Specific Skills: 

 

  • You will develop the skills to rationalise the reaction mechanisms of the fundamental molecules of life using the curly arrow formalism of organic chemistry. 

  • You will be able to propose biochemically relevant reactivity of previously unseen molecules using the principles of organic chemistry. 

  • You will be able to predict when a cofactor will be required for a biochemical transformation. 

  • You will be trained to in using electronic resources relevant to field of organic chemistry. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

Workshop                   20% 

 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

 

Exam                          80% 

 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

 

Sustainable Development Goals:      

   

This module does not align with any of the Sustainable Development Goals, but its topics do underpin all. 

How the module will be assessed

Formative assessment: The first two workshops will be assessed formatively, and feedback provided either orally or in written form. This will give students an opportunity to consolidate the factual module content and to practice applying this to solving problems 

 

Summative assessment: An examination (80%) will assess the learning outcomes through solving of mechanistic and structural chemical problems and calculations. The relevance of these results should be used to explain biological processes and methods of chemical analysis. Information searching and retrieval skills in the context of the learning outcomes will be assessed through an online multichoice exercise (20%). 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session. 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Online Workshop/Test N/A
Exam - Spring Semester 80 Introduction to the chemistry of life exam 2

Syllabus content

Carbohydrates 

Structure of aldose and ketose sugars. Pyranose and furanose forms of sugars, alpha and beta anomers and the anomeric effect. Representation of carbohydrates as Fischer, Haworth, “zig-zag” and Mills projections. Structure of glycosides and their chemical and enzymatic hydrolysis, tests for reducing sugars. 

Structural and signalling roles played by carbohydrates in biology. 

 

Glycolysis 

Gibbs Free Energy changes and roles of ATP in driving biochemical reactions in context of glycolysis. Role of NAD+/NADH and other cofactors in redox reactions. Reactivity of thioesters and key reactions such as hydrolysis. 

Stages of glycolysis and the mechanisms of the key biological transformations. 

 

Citric Acid Cycle 

Synthesis of acetyl-CoA by the pyruvate dehydrogenase complex and the role of thiamine pyrophosphate (TPP). 

Intermediates in the citric acid cycle and the mechanisms of the chemical transformations. Outline of the electron-transport chain and ATP synthesis. 

 

Amino Acids 

Structure and stereochemistry of alpha amino acids and the side chains of the proteinogenic amino acids. 

Side chain functional groups, polarity, pKa and charge at pH 7. 

Ability of side chains to engage interactions (hydrogen bonding, hydrophobic interactions, ionic bonding). 

 

Proteins and Peptides 

Condensation of amino acids to dipeptides, polypeptides, and proteins, and (briefly) the biological significance of these molecules and polypeptide analysis. 

Role of thiamine pyrophosphate and pyridoxal phosphate (PLP) in amino acid biosynthesis.  

 

 

Reading and Resource List 

 

Lehninger Principles of Biochemistry, 8th edition, David L. Nelson and Michael M. Cox, W. H. Freeman, ISBN-13: 978-1-31-922800-2 

Organic Chemistry, 2nd Ed, J Clayden, N Greeves, S Warren, Oxford University Press, 2012. ISBN-13: 978-0199270293 

Biochemistry, 9th Edition, Jeremy M. Berg, John L. Tymoczko, Lubert Stryer, W. H. Freeman, ISBN-13: 978-1-31-911465-7  

The Organic Chemistry of Biological Pathways, 2nd Ed, J. E. McMurry, T. P. Begley, MacMillan, 2016. ISBN-13: 978-1-936221-56-1 

 

 


CH5208: Applications of Molecular Spectroscopy

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5208
External Subject Code 100417
Number of Credits 10
Level L5
Language of Delivery English
Module Leader Professor Simon Pope
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module develops the use, interpretation, analysis, and application of molecular spectroscopies. 

The application of these techniques to deduce the molecular structures of a wide variety of compounds will be described. 

Primary focus will be on the application of UV-visible absorption and nuclear magnetic resonance (NMR) spectroscopies, although the module will build on a knowledge of mass spectrometry and infrared spectroscopy. 

This module will also provide some of the theoretical framework which supports laboratory practicals and sub-topics in core organic, inorganic, and physical chemistry modules. 

On completion of the module a student should be able to

 

 

  • To describe the underlying physical principles behind modern spectroscopic techniques; 

  • To describe the qualitative and quantitative information provided by 1D and 2D NMR, and UV-vis spectroscopies; 

  • To discuss, analyse and interpret the appearance of UV-vis, 1D and 2D NMR spectra and relate to the relevant structures and physical properties of molecular species; 

  • To identify and perform problem solving strategies for the prediction of spectroscopic properties from given molecular structures;

How the module will be delivered

This module will be delivered in 22 x 1-hour lectures, supplemented by 8 x 1-hour workshops and 2 tutorials. 

Three staff will teach on the module which is split roughly into UV-vis spectroscopy (1/3) and NMR spectroscopy (2/3). 

Formative workshops are all in person and will provide problem solving experience on all aspects of the module and are regularly spaced across the module from the start. In most cases problems and exercises will be shared prior to the session. 

A summative workshop (take home exercise) will develop skills relating to the critical analysis of spectroscopic data to deduce a molecular structure of an unknown compound, and the prediction of spectral data from a given structure.  

Skills that will be practised and developed

Academic skills: 

 

  • Show an appreciation of what kind of information is provided by different spectroscopic techniques 

  • Interpret complex scientific information and relate to properties of different classes of molecules 

  • Develop diverse and effective problem-solving skills focussed upon processing multiple data sets 

 

Chemistry-Specific Skills: 

 

  • Apply concepts underpinning fundamental principles of UV-vis and NMR spectroscopies 

  • Be able to interpret IR, UV-vis, MS, and NMR data and relate to molecular structures 

  • Be able to predict sketch and accurately label 1H, 13C, 19F and 31P NMR spectra with relevant information on coupling and satellites 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Graduate Attributes – Assessment:    

  

 Written Assessment                20% 

 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 Exam                                       80% 

 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 6. Ensure availability and sustainable management of water and sanitation for all  

Goal 7. Ensure access to affordable, reliable, sustainable, and modern energy for all

How the module will be assessed

Summative assessments:  

 

Workshop (20%) is a take home exercise on unseen problems. Firstly, spectral data is given, and students must critically analyse to deduce the molecular structure of an unknown compound. Secondly, a structure of a compound is given, and you must sketch and label the predicted NMR spectrum of the compound.  

 

The summative workshop therefore assesses problem solving skills and application of knowledge. 

 

A written exam (2 hour, 80%) will test your ability to demonstrate your depth of knowledge and understanding of the syllabus content, and your ability to apply the techniques/concepts covered to unseen problems. 

 

Formative workshops (8 hours) and two formative tutorials (2 hours) will be distributed throughout the module to support your learning of key concepts, develop reflective problem-solving strategies, and encourage both independent and collaborative peer-to-peer learning. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session. 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Written Assignment N/A
Exam - Autumn Semester 80 Molecular Spectroscopy 2

Syllabus content

NMR Spectroscopy 

Revision of key concepts (coupling, resonant frequencies); 

1D NMR spectra, I = ½ (including 1H, 13C, 19F, 31P, 103Rh, 29Si); 

Decoupled spectra; 

DEPT; 

Satellites (i.e. non-100% abundant nuclei); 

Chemical vs magnetic inequivalence in inorganic and organic systems; 

Magnitude of coupling constants; 

Fluxionality (Berry mechanism, coalescence temperature); 

Prediction and analysis of NMR spectra for given molecular compounds; 

Coupling constants; 

The Karplus relationship; 

Second order coupling; 

The Nuclear Overhauser Effect; 

Exchange reactions and peak shape; 

Monitoring reactions; 

Applications of 2D NMR (COSY, HMQC/HSQC, NOESY/ROESY); 

Quadrupolar nuclei; 

   

UV-vis spectroscopy  

Selection rules and revision of Beer Lambert law; 

Spectrometer basics; sample types 

Modern commercial applications of UV-vis spectroscopy 

 

Appearance of bands; Franck-Condon; from potential diagrams to spectra (vibronic structure) 

Jablonski energy level diagrams 

Types of electronic transition: π-π*, n-π*, CT; MLCT, LMCT (d-d, f-f briefly) 

Relationship of electronic transitions to molecular structures of aromatic molecules; 

Influence of conjugation and substituents on absorption properties; 

Influence of pH on absorption properties; 

Comparison of charge transfer species in aromatic organics and metal complexes; 

Solvent dependence (positive and negative solvatochromism) of CT transitions; 

Charge transfer complexes in donor acceptor mixtures; 

 

 

Essential Reading and Resource List 

 

References to the primary literature will be given throughout and you will be expected to utilise WoK to access supporting information to the lecture notes. 

 

Background Reading and Resource List 

 

Atkins – Physical Chemistry 

Banwell – Fundamentals of Molecular Spectroscopy 

Brisdon – Inorganic Spectroscopic Methods (Oxford Primer) 

Hore – NMR (Oxford Primer) 

Iggo – NMR Spectroscopy in Inorganic Chemistry (Oxford Primer) 

Organic Structure Determination using 2D NMR Spectroscopy, A problem-based approach, Jeffrey Simpson 

 


CH5210: Further Chemistry Laboratories

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5210
External Subject Code 100417
Number of Credits 30
Level L5
Language of Delivery English
Module Leader Dr Thomas Slater
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

Laboratory chemistry is central to a thorough appreciation for the subject as a whole. This module delivers practical and interpretation skills spanning the whole range of chemistry. Experiments covering the areas of organic, biological, inorganic, physical, analytical chemistry and spectroscopy will be carried out. The experimental outputs (samples, datasets, spectra) will be interpreted and analysed. Experimental results will be linked with the appropriate theory and mechanism to deliver a coherent and holistic view of the subject. 

Various pre-lab activities, including some teaching of spectroscopy and chromatography, will support the in-lab and related activities. 

There will be an emphasis on safety and correct working practice. 

On completion of the module a student should be able to

Undertake a range of synthetic chemistry transformations and physical chemistry investigations using appropriate laboratory equipment in a safe manner. These experiments are typically more involved than those in CH5110. 

Understand the importance of an experiment in terms of the skills being developed, and to relate the experimental output to the underlying theory. 

Present and critically evaluate experimental data in a structured and rigorous manner. 

Identify deficiencies in experimental data, and propose new experiments that will address any such deficiencies. 

 

How the module will be delivered

Prior to each laboratory session, students will be required to engage with online resources to fully prepare them to undertake the practical work and to demonstrate an appreciation of safety. 

Students will carry out a structured series of experiments, working closely with experienced demonstrators who will be responsible for the supervision and assessment/feedback on the experiment. 

Following each experiment or group of experiments, discussion and feedback sessions will be held so that students can develop and practice key skills relating to the understanding and interpretation of experimental data. 

Content that is closely allied with experimental work, specifically spectroscopy and chromatography, will be delivered to further cement the link between experiment and theory. 

 

Skills that will be practised and developed

Intellectual Skills 

  • You will learn to select and apply techniques and experimental designs that are used across the breadth of chemistry. 

Chemistry-Specific Skills 

  • You will carry out experimental work in synthetic chemistry, preparing chemicals which are then purified using common procedures. 

  • You will assess the structure, purity and physico-chemical properties of compounds using a range of analytical and spectroscopic methods. 

Transferable Skills 

  • You will prepare rigorous reports that describe the conduct, findings and conclusions of experimental work. 

  • You will accurately record measurements and observations from experiments. 

  • You will use appropriate software (including specific chemical drawing and analysis software) to produce reports of a high standard. 

 

 

How the module will be assessed

 

Formative feedback will be delivered on all aspects during the laboratory sessions by academic supervisors and demonstrators. At the end of each experiment, experimental data and/or samples will be evaluated for summative assessment, with immediate feedback given. The overall quality of working and output will contribute to the ‘Lab Work’ component of assessment. 

Formative feedback will be delivered during a session after completion of each experiment by all groups. This will then feed into two submissions of data interpretation and analysis, one per semester. 

At two points in the module, you will submit an extended experimental write-up, as part of a portfolio of assessment, covering one synthetic chemistry and one instrumental chemistry experiment. Experiments will be written up in a style designed to develop professional standards of reporting. Each of these portfolios will be summatively assessed, with feedback on the first portfolio able to be used to improve the second portfolio. All learning outcomes will be covered, with a focus on learning outcome 2. 

Students are required to pass each individual component of this module. All assessments will contribute to the delivery of all learning outcomes. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

Students who do not pass the ‘Practical Work’ component of this module will be required to resit as an internal student during the next academic session. 

Students who do not pass one or more of the ‘Portfolio’ components will be provided with a resit opportunity over the summer following the academic session. 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

Type of assess     Contrib.  Title              Duration    Approx. date of Assess.   Qualifying Mark 

PSA                       50                  Lab Work                        Oct-May                              40 

CW                        50                  Lab Write Ups                 Nov-May                             40 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 120 Autumn Lab Reports N/A
Written Assessment 180 Spring Lab Reports N/A
Written Assessment 100 Autumn Quizzes N/A
Written Assessment 100 Spring Quizzes N/A
Practical Skills Assessment 33 Instrumental 1 N/A
Practical Skills Assessment 33 Instrumental 2 N/A
Practical Skills Assessment 33 Instrumental 3 N/A
Practical Skills Assessment 33 Instrumental 4 N/A
Practical Skills Assessment 33 Instrumental 5 N/A
Practical Skills Assessment 33 Instrumental 6 N/A
Practical Skills Assessment 33 Instrunmental 7 N/A
Practical Skills Assessment 33 Instrumental 8 N/A
Practical Skills Assessment 33 Synthetic 1 N/A
Practical Skills Assessment 33 Synthetic 2 N/A
Practical Skills Assessment 34 Synthetic 3 N/A
Practical Skills Assessment 34 Synthetic 4 N/A
Practical Skills Assessment 34 Synthetic 5 N/A
Practical Skills Assessment 34 Synthetic 6 N/A
Practical Skills Assessment 34 Synthetic 7 N/A

Syllabus content

All aspects are mandatory. 

Application of synthetic chemistry techniques to the preparation, purification and characterization of a range of organic and inorganic compounds (e.g., organometallic compounds, coordination compounds). 

Experimental determination of thermodynamic and kinetic parameters of reactions, colloidal and surface processes (spectrophotometric and potentiometric methods). Presentation of data and application of theory to determine parameters. 

Use of basic computational chemistry software for the exploration of chemical structure and reactivity. 

Application of spectroscopic data (UV, IR, NMR) for assigning structure and stereochemistry. 

 


CH5225: Communicating Chemistry: Key Skills for Medicinal Chemists

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5225
External Subject Code 100420
Number of Credits 10
Level L5
Language of Delivery English
Module Leader Dr Angelo Amoroso
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

In this module you will learn how to efficiently and effectively search for and retrieve information within the vast chemical literature.  

 

You will gain skills in presenting experimental procedures, chemical data, and concepts both in writing and orally to diverse audiences.  

 

You will gain experience with the digital tools that are available for communication through different media.  

 

You will have opportunities to enhance your employability, by developing your team working, proficiency in information technology and articulating your skills to potential employers. 

 

On completion of the module a student should be able to

  • Locate, retrieve, and evaluate chemical information from books, journals, and specialised databases.  

  • Articulate chemical concepts, information, and skills proficiency to both expert and non-expert audiences through oral presentation, writing and digital media.  

  • Work in a team to accomplish a presentation task on time. 

How the module will be delivered

11 x 1-hour lectures and workshops.  

 

These will be a mixture of lecture type presentations and workshop events.  

 

Additional online resources will also be provided. 

Skills that will be practised and developed

 

Intellectual skills: 

 

  • Ability to analyse a topic in order to prepare for an oral, written, or visual presentation  

  • Use of critical analysis to choose and present material of an appropriate level for a given audience.  

 

Chemistry-Specific Skills:  

 

  • Use of chemistry specific databases to retrieve chemical information  

  • Use of chemistry specific drawing and visualisation software to present diagrammatic data  

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:   

  

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Show an appreciation of organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Appreciate organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Graduate Attributes – Assessment:    

  

Poster Presentation                      20%  

 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate, and present with impact. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Oral Presentation                          30% 

 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate, and present with impact. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Written Assessment                      50% 

 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate, and present with impact. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 3. Ensure healthy lives and promote well-being for all at all ages  

Goal 4. Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all 

 

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, and decent work for all  

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development 

 

 

How the module will be assessed

 

The module is summatively assessed via three tasks, a group poster, a written literature review essay, and a non-technical oral presentation. The poster and talk will involve an element of peer assessment.   

  

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session. 

 

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 50 Literature Review Essay N/A
Presentation 30 Oral Presentation N/A
Presentation 20 Group Poster Presentation N/A

Syllabus content

Data-base searching e.g. Scopus, Web of Knowledge, Sci-finder.  

 

Use of a reference manager program.  

 

Use of chemical drawing software.  

 

Correct referencing and acknowledgement; avoidance of plagiarism.  

 

Using critical analysis to choose appropriate topics for presentations (visual, written, and oral).  

 

Translation of complex scientific information and communicating it effectively, taking into account the audience and context.  

 

Verbal and visual presentation skills, to be used in a group poster and a short talk.  

 

Written presentation skills, including the identification and communication of key messages.  

 

Evaluation of the effectiveness of the communication of science in different contexts (e.g. print, video media, posters).  

 

Career reflection, job application and interview skills (to be taught with assistance from Student Futures). 


CH5230: Practical Skills in Medicinal Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5230
External Subject Code 100420
Number of Credits 30
Level L5
Language of Delivery English
Module Leader Dr Fabrizio Pertusati
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module will give you an introduction into modern practical skills in medicinal chemistry. 

 

This will include hands-on training in often-used reactions and set-ups in the field as well as handling of biological macromolecules.  

 

In addition, you will have the chance to use of state-of–the-art equipment, such as flow reactors, an automatic chromatographic purification system and a scale-up reaction vessel.  

 

Medicinal chemistry concepts, such as 3-D shape complementarity, Structure Analysis Relationship (SAR) analysis and physicochemical properties will be interwoven into the module, using the appropriate software.  

 

You will use medicinal chemistry concepts to take responsibility of which compounds to synthesise next and how to save a chemical series by targeted chemical modification of the lead compound.  

 

You will be instructed in methods essential for data acquisition and reporting to professional standards. There will be the opportunity to critically evaluate published, peer reviewed research. 

 

On completion of the module a student should be able to

  • Safely carry out a range of reactions of organic and biological molecules using state-of-the-art laboratory equipment.  

  • Make independent decisions on which compounds should be made next and how on a typical medicinal chemistry project based on logical medicinal chemistry concepts.  

  • Present experimental procedures, data, and interpretations in a precise, concise, and professional manner.  

  • Critically evaluate and draw conclusions from scientific information from synthetic and biological experiments and published sources. 

How the module will be delivered

This module will be delivered through blended learning. Online resources will supplement hands-on learning in the teaching laboratory:  

 

  • Online laboratory manuals will allow you to plan experimental work beforehand in a safe and timely manner and also introduce key medicinal chemistry concepts (learning outcomes 1, 2)  

 

  • You will carry out eight synthetic experimental experiments, four biological experiments with an additional four computational experiments being delivered live online (learning outcomes 1 – 4)  

 

  • You will take part in a journal club where you will critique a publication in an oral presentation.

Skills that will be practised and developed

 

Chemistry Specific Skills: 

 

  • Carry out COSHH and risk assessments to ensure safe practice prior to experimental work.  

  • Performing scientific calculations critical for proper reagent preparation.  

  • Essential practical skills in synthetic chemistry and handling proteins and nucleic acids   

  • Identify and assess the purity of reaction products using modern analytical and spectroscopic methods  

  • Problem-solving to save a chemical series from a common fault by fine-tuning of a basic centre.  

  • Thinking in 3-D by learning how to draw, minimise the energy of and overlay molecules in silico   

  • Analyse and spot SAR trends with regards to activity and lipophilicity  

  • Using software packages in the field of medicinal chemistry and statistics  

  • Prepare concise and accurate scientific reports of experimental data and procedure  

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:   

  

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.   

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Graduate Attributes – Assessment:    

  

Presentation                                      20% 

 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Practical Skills Portfolio                     80% 

 

  •  Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 6. Ensure availability and sustainable management of water and sanitation for all

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development 

 

How the module will be assessed

There are 2 points of assessment in this module:  

Practical skills portfolio (80%)  

Students will compile a portfolio where they will be required to evidence the following aspects of practice: 

Consistent attendance and active engagement in practical sessions. 

Proficiency in safely performing standard techniques in synthesis and analysis. For some experiments this may include an assessment of the quality of physical samples according to appearance, 1H NMR spectroscopic and LC/MS analysis. 

Operating common equipment in the medicinal chemistry laboratory.   

Recording of experimental procedures and outcomes in a professional style that would enable reproduction of the experiment. 

Reporting of analytical data in the style of a chemistry journal. 

Interpretation of analytical data to deduce or confirm chemical structure. 

Use of software for statistical analysis and graphical presentation of numerical data. 

Use of software of calculation and visualisation of 3-D structure and molecular properties. 

Decision making and planning what compounds to make and how by applying medicinal and synthetic chemistry principles. 

Mechanistic interpretation of chemical reactions. 

Problem solving using a combination of medicinal chemistry concepts and appropriate software to overcome challenges in biological activity and synthesis.  

A reflective commentary describing skills development, signposting the evidence of the above skills and discussing what might have been done differently to improve experimental outcomes. 

Formative feedback on the portfolio will be provided at the end of autumn semester. 

Journal Club (20%) 

Students will be individually assessed in the form of a short presentation in a ‘Journal club’-style workshop. Each student will present a critical evaluation of a peer reviewed published paper. 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

An attendance register will be kept at laboratory sessions. Students who do not pass the ‘Practical Skills Portfolio” component of this module due to lack of attendance at laboratory sessions will be required to resit as an internal student during the next academic session. If students have attended laboratory sessions, students will be permitted to revise and resubmit their portfolio during the resit period. 

Since the journal club consists of a group discussion, the student will not be able to resit this assignment in its original form. Instead, in the summer, they will be asked to provide a written critique of an assigned journal article and then discuss it with the appropriate staff member. 

 

Assessment Breakdown

Type % Title Duration(hrs)
Report 10 Autumn Synthetic Lab Report N/A
Class Test 10 Autumn Computational Online Quiz N/A
Presentation 20 Journal Club N/A
Report 60 Spring Lab Report N/A

Syllabus content

Practical experience with laboratory equipment for synthetic organic chemistry and purification, including handling air-sensitive reagents.  

 

Synthetic and purification techniques will be illustrated using a variety of reactions that are commonly employed in medicinal chemistry which may include Pd-catalysed C-C coupling and organometallic reactions, SNAr reactions, amide couplings, heterocycle-forming condensation reactions, reductive aminations, late-stage fluorination and protecting group chemistry.  

 

Fundamental mechanistic principles of common synthetic reactions in medicinal chemistry and their place in synthetic strategy.  

 

Principles of operation of laboratory equipment for synthesis and testing of drugs candidates.  

 

Use of apparatus including flow reactors, an automatic chromatographic purification system and a scale-up reaction vessel.  

 

Practical skills in pipetting and buffer making.  

 

Polymerase Chain Reaction – theory and practice.  

 

Gel electrophoresis and blotting – practical technique and data interpretation.  

 

Use of computational chemistry software for prediction of molecular shape, physicochemical properties (in silico 3-D shape complementarity, calculation of pKa and lipophilicity) and analysis of structure-activity relationships.  

 

Use of software for statistical analysis, graphing, and data presentation.  

 

Literature search/critiquing and evaluating a scientific paper.  

 

Essay writing skills and referencing. 


CH5231: Physical Chemistry in Drug Design

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5231
External Subject Code 100420
Number of Credits 10
Level L5
Language of Delivery English
Module Leader Dr Fabrizio Pertusati
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module will set out the essential concepts of physical chemistry that underpin key aspects of medicinal chemistry. 

This will include descriptions of intermolecular forces and their modelling in computer software to describe the interactions between drugs and their targets as well as the properties and behaviour of drugs in relevant systems, such as the body and in formulation. 

On completion of the module a student should be able to

  • Discuss the origin and importance of intermolecular interactions, including hydrogen bonding, dispersion, electrostatics, and induction and how they influence the properties of drugs.  

  • Evaluate drug-protein interactions, protein-protein interactions, solubility, and other pharmaceutical parameters in terms of molecular interactions and thermodynamics.  

  • Apply kinetic descriptions to processes of pharmacological relevance such as enzyme kinetics and pharmacokinetics.  

  • Compare different approaches to modelling the intra- and intermolecular forces using molecular mechanics and assess which approach is most applicable to a challenge in medicinal chemistry.

How the module will be delivered

Content will largely be delivered through 22 x 1-hour lectures, addressing all learning outcomes. 

These will be supplemented by workshops and tutorials that will selectively address learning outcomes with an emphasis on problem solving and forging links between topics.

Skills that will be practised and developed

Chemistry-Specific Skills: 

 

  • Applying concepts from fundamental physical chemistry to understand the behaviour of drugs and their biomolecular targets.  

  • You will develop a detailed understanding of kinetics, thermodynamics, and intermolecular forces and how these are related to observed phenomena.  

  

Employability skills:     

   

This module is delivered and aligns with the following University Graduate Attributes:     

   

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

   

Graduate Attributes – Assessment:    

  

Online Quiz              20% 

 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Exam                        80% 

 

  • Deliver, accept, and act on constructive feedback.  

  • Consider own personal and professional ethical, social, and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

   

Sustainable Development Goals:      

   

This module is delivered and aligns in working towards the following Sustainable Development Goals:    

  

Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture 

Goal 3. Ensure healthy lives and promote well-being for all at all ages

Goal 6. Ensure availability and sustainable management of water and sanitation for all

Goal 15. Protect, restore, and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss 

 

 

How the module will be assessed

Formative assessment: Workshops and tutorials will be assessed formatively, and feedback provided either orally or in written form. This will prepare you to tackle problem-solving exercises in the examination.  

 

Summative assessment: A written exam (2 hours) will test your ability to demonstrate your knowledge and understanding of the syllabus content, and your ability to apply the techniques/concepts covered to unseen problems.  

 

An online quiz will allow you to demonstrate your ability to solve medicinal chemical problems.  

 

The online quiz will focus on your ability to use and interpret numerical data representing physical properties to predict pharmacological properties of drugs. Marks will reflect the extent to which you have met the module learning outcomes shown above.  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session. 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Summative Online quiz N/A
Exam - Autumn Semester 80 Physical Chemistry in Drug Design 2

Syllabus content

Intra- and intermolecular forces:   

 

dispersion forces, electrostatic interactions, hydrogen bonding, halogen bonding, & hydrophobic effect. 

Molecular interactions and pharmaceutical parameters as consequences of intra- and intermolecular forces. 

Aqueous solubility, lipophilicity, effects of protonation state and pKa, logP, c-logP, logD, PEGylation for increasing aqueous solubility, group additivity approaches to estimate pharmaceutical parameters; 

Hunter’s hydrogen-bonding model for molecular interactions; 

Small-molecule-protein interactions, protein-protein interactions 

Drugs and physiology, volume of distribution, cell membrane is an aqueous-lipophilic-aqueous type barrier, serum albumin as carrier protein;  

QSAR: Structure – function relationships; 

Drug administration routes; 

Molecular interactions in drug formulation; 

Modelling the intra- and intermolecular forces with molecular mechanics:  

Born-Oppenheimer, functional forms for bonded and non-bonded, parameters and specific forcefields for medicinal chemistry 

Applications of molecular mechanics: conformational searching, drug-receptor docking, introduction to molecular dynamics.  

 

Thermodynamics:   

 

Recap of concepts: enthalpy, entropy, free energy, equilibrium constants;  

Thermodynamics of protein structure and folding;  

Cold and hot denaturation; 

Thermodynamics of drug-receptor and protein-protein interaction;  

Techniques for determination of thermodynamics quantities.  

 

Kinetics:   

 

Recap of concepts: 0th, 1st, 2nd order reactions, Arrhenius model;  

Enzyme kinetics: Michaelis-Menten model, cooperativity, inhibition and activation, complex reactions;  

Pharmacokinetics: 

ADMET: adsorption, distribution, volume distribution, metabolism, excretion, toxicity, and bioavailability  

Overview of pathways of drug excretion and degradation (e.g. CYP450 degradation); 

Use of prodrugs to achieve desired properties; half-life of drug in body. 


CH5240: Enterprising Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5240
External Subject Code 100420
Number of Credits 10
Level L5
Language of Delivery English
Module Leader Dr Angelo Amoroso
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module will provide Chemistry students with the business skills necessary to turn opportunities that emerge from their chemistry knowledge into a successful enterprise.  

Working with experts from Cardiff Business School, module participants will explore different facets of business such as marketing, strategy, and operations management, to provide them with an organisational framework and the business knowhow needed to make their entrepreneurial aspirations a reality.  

Particular attention will be paid to the particular challenges of chemistry related enterprises such as how rigorous health and safety practices can underpin a successful approach to business.   

 

On completion of the module a student should be able to

  • Critically evaluate and analyse different business models, by identifying key business strategies and their effectiveness.  

  • Examine the interrelationship between, and impact of, key business principles such as marketing, operations management, (digital technologies) and financial awareness.  

  • Recognise and apply key components of a successful business plan through the design of an effective business plan.  

  • Effectively communicate, orally and in writing, key business principles and strategies to a diverse audience with varying stakeholder interests and needs.  

How the module will be delivered

This module will be shared via a series of short lectures and expert insights from successful entrepreneurs.  Case studies will be used to illustrate best practice examples from business and students – they will synthesise these cases in group activities. 

Some of the sessions will include guest speakers who run their own business.  Group discussions will follow guest speakers to ensure that key learning points are identified. 

The concept of the business plan will be introduced early in the programme and will be referred to at different points throughout the programme where relevant.  

Skills that will be practised and developed

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:  

 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Understand organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Graduate Attributes – Assessment:    

  

 Presentation                                 40% 

 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate, and present with impact. 

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted. 

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Understand organisations, their stakeholders, and their impact on the community. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

 Written Assessment                     60% 

 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate, and present with impact. 

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted. 

  • Consider own personal and professional ethical, social, and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Understand organisations, their stakeholders, and their impact on the community. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, and decent work for all  

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

Goal 12. Ensure sustainable consumption and production patterns  

Goal 13. Take urgent action to combat climate change and its impacts 

Goal 15. Protect, restore, and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss  

 

How the module will be assessed

Distinguish between successful and unsuccessful business practices  

Formative assessment through group work flip chart exercises   

Appreciate key principles of productive marketing practices  

Formative assessment through interpretation of case studies  

Discover the core tenets of successful business strategy  

Formative assessment via mentimeter  

Summarise important operations management principles  

Formative assessment of groups feeding back their summaries following operations management session  

 

Display an appreciation of basic finance knowledge required to create a business plan  

Summative assessment via business plan  

Evaluate the importance of considering incorporating digital within your approach to business  

Summative assessment via presentation and business plan  

Demonstrate their understanding of the important components of successful business through the completion of a comprehensive business plan – summative assessment via business plan  

Ability to communicate your business idea to a range of different stakeholders  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

Should you fail the module you will be able to submit a recorded version of your individual presentation. Should you fail the business plan element, following extra guidance from a module coordinator, you can make adjustments needed to your business plan and resubmit.   

Assessment Breakdown

Type % Title Duration(hrs)
Presentation 40 Communication of student's business idea and plan N/A
Written Assessment 60 Business Plan N/A

Syllabus content

The programme of activity has been designed to provide a comprehensive introduction into all of the necessary components of running your own business. Proposed topics include:  

 

1. Introduction, oversight, and assessment explanation    

 

Setting the scene – why having different routes for your career is advantageous, benefits of being a business owner and examples of successful chemist entrepreneurs  

 

2. Vision, Mission, and Brand  

 

This session will explore the importance of setting a vision for the business and being authentic to your mission and brand.  

 

3. Strategy and Innovation  

 

This session will share the important role that strategy plays in setting your direction and how it is essential to consider building innovation as a central spine to your strategic intent.  

 

4. Understanding Customers  

 

This session will discuss how you can better understand customers in order to refine your business offer and grow your market. It will discuss the difference between the voice of the customer and developing a customer mindset.  

 

5. Marketing  

 

This session builds on the theme of understanding customers and examines core principles of good marketing practice. Looking at examples of brilliant marketing, students will be encouraged to think about which marketing concepts and principles will help them in their business.  

 

6. Leadership   

 

Great leadership is the difference between mediocre businesses and fantastic ones. This session will explore key personality traits of successful leaders and will discuss concepts and techniques that can be deployed to engender great leadership.  

 

7. Teamworking  

 

This critical skill is an essential part of successful businesses, even those that just contain one employee. The need to work with, listen to and flex your approach in order to achieve a variety of different business outcomes is essential. This session will illustrate key team working principles and will encourage the students to explore them.  

 

8. Digitalisation  

 

21st Century businesses must consider technology and digitisation. This session will share examples of companies that successfully embrace digitalisation to commercial effect and will ask the students to consider how they can ensure technology is appropriately incorporated into their business  

 

9. Sustainability  

 

Another essential topic is to ensure that businesses appropriately consider environmental and social responsibility (ESR). This session will provide students with the latest thinking in this area and will help them to incorporate ESR within their business strategy and plan  

 

10. Financial Management  

 

This session will provide the fundamentals of business accounting needed to construct a viable business plan.  

 

11. Assessment session – presentation of business plan to the group  


CH5250: Macromolecules as Drug Targets

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5250
External Subject Code 100420
Number of Credits 10
Level L5
Language of Delivery English
Module Leader Dr Michaela Serpi
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module discusses the structure and chemistry of proteins, principles of protein function, receptors, enzymes, the structure and chemistry of DNA and RNA, transcription, and translation. 

Principles of enzyme catalysis and kinetics, and the effect of inhibitors will be discussed. 

Concepts for interference with biochemical pathways in medicinal chemistry will be presented throughout the module. 

The concepts of agonists and antagonists will be introduced, including models for describing these quantitatively. 

Specific examples of some of the main classes of drug targets and the mechanism of action of drugs that target them will be described. 

You will learn about the design concepts for drugs against the different classes of target.   

On completion of the module a student should be able to

 

  • Discuss the chemical, structural and functional properties of nucleic acids and proteins and how these can be exploited as drug targets.  

 

  • Quantitatively evaluate experimental data and relate this to the underlying biological processes.  

 

  • Design drugs through application of an understanding of biomacromolecule structure, function, and molecular interactions;   

 

  • Retrieve and communicate data, findings, and procedures from a variety of sources (literature, electronic databases, experiments). 

How the module will be delivered

Content will be delivered primarily using lectures (22 hours across two semesters, equating to approximately two lectures per week). 

In addition, lectures will include worked problems and informal ad hoc formative tests. This will address the learning outcomes related to knowledge and understanding. 

Workshops (2 x 1-hour formative) will be used to enhance and assess problem-solving skills. 

Coursework (summative) will involve searching, retrieval and critical analysis of data/information from the literature and/or databases. 

Tutorials (2 x 1-hour, formative) will allow provide opportunities students to students in meeting all learning outcomes. 

Skills that will be practised and developed

Chemistry-Specific Skills:  

 

  • Applying ideas from functional group chemistry and mechanistic organic chemistry to explain how the structure of proteins and nucleic acids permit them to perform their biological function.  

  • This will be demonstrated through the drawing of curly arrow pushing mechanisms.  

  • The principles of design of drugs that bind to these macromolecules through non-covalent and covalent interactions to modulate their biological function will be developed.  

  • In addition to this area of problem solving, you will also gain familiarity with interpreting and presenting data, such as enzyme kinetics, visualising biomolecular structures and retrieval of information from databases. 

 

Employability skills:     

 

This module is delivered and aligns with the following University Graduate Attributes:     

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

 Coursework 

 

  • Contribute to discussions, negotiate, and present with impact. 

  • Deliver, accept, and act on constructive feedback.  

  • Consider own personal and professional ethical, social, and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

 Exam 

 

  • Contribute to discussions, negotiate, and present with impact. 

  • Deliver, accept, and act on constructive feedback.  

  • Consider own personal and professional ethical, social, and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

 Resit Coursework 

 

  • Contribute to discussions, negotiate, and present with impact. 

  • Deliver, accept, and act on constructive feedback.  

  • Consider own personal and professional ethical, social, and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

 Resit Exam 

 

  • Contribute to discussions, negotiate, and present with impact. 

  • Deliver, accept, and act on constructive feedback.  

  • Consider own personal and professional ethical, social, and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture 

Goal 3. Ensure healthy lives and promote well-being for all at all ages 

Goal 12. Ensure sustainable consumption and production patterns  

How the module will be assessed

Formative assessment: The first two workshops will be assessed formatively, and feedback provided either orally or in written form. Oral feedback will be provided during the tutorial sessions. This will prepare you to tackle problem-solving exercises in the examination.  

 

Summative assessment: A written exam (2-hours) will test your ability to demonstrate your knowledge and understanding of proteins and nucleic acids as drug targets, the principles of how drugs interact with these, and an ability to process and interpret experimental data relating to drug-target interactions. The coursework will allow you to demonstrate your ability to use electronic and printed resources to locate relevant data/information, to critically review literature knowledge and report the findings/conclusions through an on-line exercise. Marks will reflect the extent to which you have met the module learning outcomes shown above.  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

 

Students who are permitted by the Examining Board to be reassessed in this module during the same academic session will sit an examination (2-hour) during the Resit Examination Period. Students who fail the coursework component will be reassessed through.  

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Online Coursework N/A
Exam - Spring Semester 80 Macromolecules as Drug Targets 2

Syllabus content

Structure, biophysical properties and chemistry of nucleotides (DNA and RNA).  

 

Transcription and translation; mRNA and tRNA synthesis.  

 

The genetic code and the molecular basis of ribosomal protein synthesis.  

 

Overview of nucleic acid technologies – sequencing, PCR, and protein expression.  

 

Nucleic acids as drug targets and pharmaceuticals.  

 

Overview of protein structure. Secondary, tertiary and quaternary structure.  

 

Principles of protein function.  

 

Introduction to enzyme catalysis. Mechanisms of enzyme inhibition. Michaelis-Menten kinetics in the absence and presence of inhibitors.  

 

Quantification of drug efficacy in terms of kinetic parameters, EC50 and IC50.  

 

Examples of enzyme catalysis of relevance as targets in medicinal chemistry – kinases, serine- and metallo-proteases, monooxygenases.  

 

Structure and function of ion channels, GPCRs and nuclear hormone receptors.  

 

Role of these proteins as drug targets with examples of drugs illustrating their mode of action and the drug design principles.  

 

Proteins as drugs – opportunities and challenges for drug development. 


CH5253: Cemeg Organig pellhach a Chemeg Biolegol

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5253
External Subject Code 100417
Number of Credits 20
Level L5
Language of Delivery Welsh
Module Leader Dr Heulyn Jones
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

Mae'r modiwl hwn yn adeiladu ar y cysyniadau a gyflwynwyd ym Mlwyddyn 1, ac yn rhoi trosolwg mecanistig cydlynol o grwpiau gweithredol organig allweddol, gan gynnwys eu synthesis a'u hadweithedd.  

 

Ar ôl trosolwg o gemeg grŵp carbonyl datblygedig, mae'r modiwl yn ymchwilio i synthesis ac adweithedd cyfansoddion aromatig, heteroaromatig a heterogylcol – blociau adeiladu cemegion cyffredin ar gyfer deunyddiau sydd â phwysigrwydd cymdeithasol.  

 

Mae rhan olaf y modiwl yn cyflwyno rheolaeth stereocemegol mewn synthesis organig, gan bwysleisio arwyddocâd a rheolaeth trefniadau tri dimensiwn atomau mewn moleciwlau. 

On completion of the module a student should be able to

  • Adnabod ac egluro adeiledd cyffredinol ac adweithedd amrywiaeth o gyfansoddion organig dirlawn ac annirlawn, gan gynnwys alcenau, carbonylau, a chyfansoddion aromatig a heteroaromatig. 

  • Cymhwyso’r egwyddorion sylfaenol sy’n pennu a all adwaith fod yn gemoddetholus, regioddetholus neu stereoddetholus, a'r sail egnïol ar gyfer detholedd mewn ystod o drawsnewidiadau organig. 

  • Rhagweld a rhesymoli canlyniad adweithiau organig gan ddefnyddio'r confensiwn saeth cyrliog ar gyfer mecanweithiau adwaith. 

  • Defnyddio dulliau rhesymu mecanistig sy’n seiliedig ar lwybrau adwaith hysbys i ddiddwytho mecanweithiau tebygol adweithiau sy’n anhysbys. 

  • Dylunio synthesis cyfansoddyn stereobenodol neu heterogylchol gan ddefnyddio deunydd a gwmpesir mewn cemeg organig Blwyddyn 1 a chynnwys maes llafur y modiwl hwn. 

How the module will be delivered

44 o ddarlithoedd awr o hyd a gweithdai ffurfiannol, pedwar tiwtorial awr o hyd; wedi'u rhannu'n gyfartal ar draws dau semester.  

 

Bydd cynnwys yn cael ei gyflwyno'n bennaf trwy ddarlithoedd. 

 

Defnyddir darlithoedd i ddarparu cynnwys sy'n gysylltiedig â'r holl ddeilliannau dysgu. Bydd y rhain yn cael eu cyfnerthu gan waith tiwtorial, sy'n darparu adborth wedi'i deilwra i fyfyrwyr.  

 

Bydd gweithdai ffurfiannol ac adborth yn canolbwyntio ar ddatrys problemau, wedi'u pwysoli'n fwy tuag at ddeilliannau dysgu 3–5. 

Skills that will be practised and developed

Sgiliau Academaidd: 

 

  • Bydd yr asesiadau ffurfiannol a chrynodol yn mireinio eich gallu i gyfathrebu ac egluro cysyniadau cymhleth yn glir ac yn wrthrychol, boed ar lafar neu ar ffurf ysgrifenedig. 

 

Sgiliau pwnc-benodol: 

 

  • Ar ôl cwblhau'r modiwl, byddwch yn gallu cymhwyso meddwl rhesymegol i gynllunio synthesis organig. Yn benodol, byddwch yn fedrus wrth ddewis a nodi strategaethau, adweithyddion, adweithredyddion ac amodau adwaith priodol yn seiliedig ar yr egwyddorion integredig a ddysgwyd ym mlynyddoedd 1 a 2. 

  • Byddwch yn datblygu gwell gwerthfawrogiad o rywogaethau cemegol a biolegol fel endidau tri dimensiwn, gan ennill hyfedredd wrth gydnabod sut mae eu cyfansoddiad a'u hadeiledd 3D yn dylanwadu ar adweithedd. 

  • Ar y cyd â'r modiwlau labordy, byddwch yn cysylltu cysyniadau damcaniaethol â chemeg ymarferol

 

Sgiliau cyflogadwyedd:    

  

Mae'r modiwl hwn yn cael ei gyflwyno ac yn cyd-fynd â’r Rhinweddau Graddedigion Prifysgol canlynol:  

   

  • Cyfrannu at drafodaethau, negodi, a chyflwyno’n effeithiol.  

  • Ystyried eu cyfrifoldebau moesegol, cymdeithasol ac amgylcheddol personol a phroffesiynol.  

  • Dangos gonestrwydd, dibynadwyedd a gallu personol a phroffesiynol.  

  • Cofio am yr argyfwng hinsawdd a nodau datblygu cynaliadwy’r Cenhedloedd Unedig  

  • Nodi, diffinio a dadansoddi materion a syniadau cymhleth, gan arfer barn feirniadol wrth werthuso ffynonellau gwybodaeth.  

  • Dangos chwilfrydedd deallusol ac arddangos y gallu i ddefnyddio gwybodaeth mewn modd sy'n dangos gwerthfawrogiad dwfn o'r ffeithiau. 

  • Ymchwilio i broblemau a chynnig datrysiadau effeithiol, myfyrio a dysgu o lwyddiannau a methiannau.  

  • Creu syniadau gwreiddiol a chymhwyso ffyrdd creadigol, llawn dychymyg a dyfeisgar o feddwl wrth ymateb i anghenion a phroblemau a nodwyd.  

  • Mynd ati’n bwrpasol i fyfyrio ar eu hastudiaethau eu hun, eu cyflawniadau a’u hunaniaeth  

  • Dangos gwydnwch, hyblygrwydd a chreadigrwydd i ddelio â heriau, a bod yn agored i newid.  

  • Adnabod a mynegi eu sgiliau eu hunain, a chymhwyso gwybodaeth yn hyderus ac mewn amrywiaeth o gyd-destunau.  

  • Ystyried syniadau, cyfleoedd a thechnolegau newydd, gan adeiladu ar wybodaeth a phrofiad i wneud penderfyniadau gwybodus am eu dyfodol eu hunain. 

 

  

Rhinweddau Graddedigion – Asesiad:    

  

 Gwaith cwrs          20% 

 

  • Nodi, diffinio a dadansoddi materion a syniadau cymhleth, gan arfer barn feirniadol wrth werthuso ffynonellau gwybodaeth. 

  • Arddangos chwilfrydedd deallusol a cheisio meithrin gwybodaeth a dealltwriaeth. 

  • Creu syniadau gwreiddiol a chymhwyso ffyrdd creadigol, llawn dychymyg a dyfeisgar o feddwl wrth ymateb i anghenion a phroblemau a nodwyd. 

 

 Arholiad                  80% 

 

  • Nodi, diffinio a dadansoddi materion a syniadau cymhleth, gan arfer barn feirniadol wrth werthuso ffynonellau gwybodaeth. 

  • Arddangos chwilfrydedd deallusol a cheisio meithrin gwybodaeth a dealltwriaeth. 

  • Creu syniadau gwreiddiol a chymhwyso ffyrdd creadigol, llawn dychymyg a dyfeisgar o feddwl wrth ymateb i anghenion a phroblemau a nodwyd. 

 

  

Nodau Datblygu Cynaliadwy:     

  

Cyflwynir y modiwl hwn mewn modd sy'n cyd-fynd â gweithio tuag at y nodau datblygu cynaliadwy canlynol:   

 

Nod 2. Rhoi terfyn ar newyn, sicrhau diogelwch bwyd a gwell maeth, a hyrwyddo amaethyddiaeth gynaliadwy  

Nod 3. Sicrhau bywydau iach a hyrwyddo lles i bawb o bob oedran

Nod 12. Sicrhau defnydd a phatrymau cynhyrchu cynaliadwy 

Nod 15. Amddiffyn, adfer a hyrwyddo defnydd cynaliadwy o ecosystemau daearol, rheoli coedwigoedd yn gynaliadwy, mynd i’r afael â diffeithdiro, ac atal a gwyrdroi diraddiad tir ac atal colli bioamrywiaeth  

 

How the module will be assessed

Asesu Ffurfiannol: Mae'r asesiadau'n darparu cyfleoedd amserol i fyfyrwyr adolygu a chymhwyso egwyddorion a ddysgwyd yn y modiwl hwn i fynd i'r afael ag ymarferion datrys problemau. Maent yn cael eu cynnal ar ffurf gweithdai yn y dosbarth a thiwtorialau grŵp bach; bydd adborth yn cael ei ddarparu naill ai ar lafar neu yn ysgrifenedig.  

 

Asesiad Crynodol: Bydd archwiliadau ysgrifenedig yn cynnwys problemau yn seiliedig ar ddeunyddiau'r darlithoedd sy'n cael eu hehangu i gynnwys moleciwlau ac adweithiau nas gwelwyd o'r blaen. Mae'r asesiadau hyn yn caniatáu i fyfyrwyr ddangos eu bod wedi meistroli'r deilliannau dysgu deallusol a modiwl benodol. Pwysleisir y marcio ar y disgrifiad rhesymol o adweithedd grwpiau swyddogaethol, y gallu i ddiddwytho canlyniad a mecanwaith synthesis aml-gam, a'r rheolaeth stereocemegol yn seiliedig ar siâp tri dimensiwn moleciwlau. Mae prawf mis Ionawr yn gyfle i dderbyn adborth ar gynnydd myfyrwyr tuag at y deilliannau dysgu. 

 

Y CYFLE AR GYFER AILASESIAD YN Y MODIWL HWN: 

Caniateir cyfleoedd i ailasesu, ar yr amod nad yw myfyrwyr wedi methu mwy o gredyd nag yn y rheol ailsefyll a fabwysiadwyd gan eu rhaglen. Bydd myfyrwyr a ganiateir gan y Bwrdd Arholi i gael eu hailasesu yn y modiwl hwn yn ystod yr un sesiwn academaidd yn sefyll arholiad yn ystod y Cyfnod Arholiadau Ailsefyll (tua mis Awst) cyn dechrau'r sesiwn academaidd ganlynol. Bydd fformat yr ailasesiad yn union yr un fath â'r un gwreiddiol.  

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Gwaith cwrs N/A
Exam - Spring Semester 80 Cemeg organig pellhach 3

Syllabus content

Semester yr Hydref  

 

Cemeg carbonyl 3: Enghreifftiau pellach o enolau a chemeg enoladau: cyddwysiadau aldol croes a Knoevenagel a chyddwysiadau cysylltiedig. Adwaith Mannich. Cemeg Deuanionau. Enoladau cinetig a thermodynamig (gan ffurfio silyl enol ether). Yr adwaith Wittig a'i amrywiadau. Cemeg sylffocsidau, sylffonau a sylffocsiminau o fath enolad. Adweithiau amineiddio rhydwythol. 

 

Cemeg alcenau 2: Hydroboradu ac epocsidio alcenau. Osonolysis alcenau. Deuhydrocsyladu deuolau ac ymraniad ocsidiol deuolau. 

 

Ad-drefniadau: Ad-drefniad carbocadu. Yr ad-drefniad pinacol a'r ad-drefniad lled-binacol. Mudiad i nitrogen ac ocsigen electron-ddiffygiol (ad-drefniadau Baeyer-Villiger, Beckmann, Curtius ac ad-drefniadau cysylltiedig – Hofmann, Lossen, Schmidt). 

 

Cyfunedd: Ychwanegiad cyfunedd at cyfansoddion carbonyl alpha, beta-annirlawn. Organocwpradau a niwcleoffilau o fath malonad (gan gynnwys adweithiau modrwyweddu o fath Robinson). Adwaith Baylis-Hillman.  

 

Cemeg aromatig 2: Amnewid aromatig niwcleoffilig (SNAr). Halwynau deuasoniwm (adweithiau Sandmeyer). Ffurfiad bensyn a’i adweithedd.  

 

 

Semester y Gwanwyn  

 

Adweithedd cyfansoddion heterogylchol aromatig: Gwahaniaeth ym masigedd ac adweithedd pyridin, pyrrol, indolau ac imidasolau. Amnewid electroffilig mewn systemau heteroaromatig. Amnewidiad niwcleoffilig mewn systemau heteroaromatig halogenedig. Heterogylchoedd metaleiddio C. 

 

Synthesis heterogylchol aromatig: Dadansoddiad a synthesis retrosynthetig o systemau heterogylchol aromatig – pyridin, pyrimidin, pyrol, ffwran, ocsasol, thiasol, imidasol, a rhai o'u analogau asio benso, gyda chysylltiadau penodol â chemeg carbonylau. Synthesis heterogylchol di-aromatig gan ddefnyddio'r adweithredyddion en(oid) a strategaeth Diels-Alder. 

 

Adweithiau ffurfio cylch: Effeithiau cydffurfiol ac orbitol mewn adweithiau ffurfio cylch. 

 

Meini prawf ar gyfer stereoddetholusrwydd: Diffiniad a mathau o stereoddetholusrwydd. Proffiliau egni ar gyfer adweithiau stereoddetholus. 

 

Adweithiau stereoddetholus a reolir gan swbstrad: Rhydwythiad cylchohecsanonau, epocsideiddio/cylchopropaneiddio alcoholau alylig cylchol. Model Cram/Felkin-Anh ar gyfer ychwanegiadau stereoddetholus at garbonylau. Cyflyrau trosiannol Zimmerman-Traxler ar gyfer adweithiau aldol diastereoddetholus. 

 

Adweithiau stereoddetholusrwydd a reolir gan adweithydd neu gatalydd: Epocsideiddiad, dihydrocsyleiddiad, hydrogeniad ac alcyleiddiad anghymesur. 


CH5257: Cyflwyniad i Gemeg Bywyd

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5257
External Subject Code 100417
Number of Credits 10
Level L5
Language of Delivery English
Module Leader Dr Matthew Tredwell
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

Mae'r modiwl hwn yn cyflwyno myfyrwyr i garbohydradau, asidau amino a phroteinau a'u rôl mewn organebau byw. 

Bydd cipolwg ar y moleciwlau sylfaenol hyn o fywyd a'u rolau yn cael ei drafod yng nghyd-destun eu priodweddau ffisegol, eu siâp, a'u hadweithedd. 

Mae'r modiwl hwn yn adeiladu ar egwyddorion cyffredinol cemeg organig a ddefnyddir i nodi patrymau adweithedd a sut mae hyn yn dylanwadu ar rolau'r moleciwlau hyn. 

On completion of the module a student should be able to

 

  • Lluniadu’r gwahanol gynrychioliadau o garbohydradau i nodi elfennau stereocemegol a rhagweld canlyniadau adwaith. 

  • Lluniadu adeileddau asidau amino proteinogenig, di-, a polypeptidau ar werthoedd pH amrywiol. 

  • Esbonio'r rhyngweithio rhwng asidau amino mewn perthynas â'r gwahanol lefelau adeileddau protein. 

  • Cysylltu adeiledd ac adweithedd cyfansoddion â’u rôl mewn cemeg bywyd. 

  • Rhagfynegi mecanweithiau saeth cyrliog ar gyfer trawsnewidiadau biolegol trwy gymhwyso egwyddorion sylfaenol cemeg organig. 

  • Datrys hafaliadau sy'n ymwneud â newidiadau mewn egni rhydd Gibbs. 

  • Defnyddio adnoddau electronig fel ChemDraw a chronfeydd data i gynhyrchu dynodwyr amgen ar gyfer moleciwlau bywyd.  

How the module will be delivered

Bydd 17 o ddarlithoedd 1 awr yn cyflwyno cynnwys craidd y cwrs, gan fynd i'r afael â'r holl ddeilliannau dysgu.

Bydd dau weithdy ffurfiannol awr o hyd a dau diwtorial grŵp bach yn gwella gwybodaeth am ddeilliannau dysgu allweddol trwy ddatrys problemau. 

Skills that will be practised and developed

Sgiliau academaidd: 

 

  • Byddwch yn cymryd rhan mewn tiwtorialau lle bydd trafodaethau ar y pynciau a godir yn eich galluogi i ddangos eich chwilfrydedd deallusol a chynnig atebion posibl, gan eich galluogi i ddatblygu eich sgiliau meddwl beirniadol a chyfathrebu llafar. 

  • Byddwch yn datblygu sgiliau mewn barn feirniadol wrth werthuso adnoddau electronig ac argraffedig o amgylch pwnc y modiwl. 

 

Sgiliau sy’n benodol i gemeg:  

 

  • Byddwch yn datblygu'r sgiliau i resymoli mecanweithiau adwaith moleciwlau sylfaenol bywyd gan ddefnyddio ffurfiolaeth saeth cyrliog cemeg organig. 

  • Byddwch yn gallu cynnig adweithedd biocemegol perthnasol o foleciwlau nas gwelwyd o'r blaen gan ddefnyddio egwyddorion cemeg organig. 

  • Byddwch yn gallu rhagweld pryd y bydd angen cydffactor ar gyfer trawsnewid biocemegol. 

  • Byddwch yn cael eich hyfforddi i ddefnyddio adnoddau electronig sy'n berthnasol i faes cemeg organig. 

 

Sgiliau cyflogadwyedd:    

  

Mae'r modiwl hwn yn cael ei gyflwyno mewn modd sy’n cyd-fynd â’r Rhinweddau Graddedigion Prifysgol canlynol:    

 

  • Cyfrannu at drafodaethau, negodi, a chyflwyno’n effeithiol.  

  • Ystyried eu cyfrifoldebau moesegol, cymdeithasol ac amgylcheddol personol a phroffesiynol.  

  • Dangos gonestrwydd, dibynadwyedd a gallu personol a phroffesiynol.  

  • Cofio am yr argyfwng hinsawdd a nodau datblygu cynaliadwy’r Cenhedloedd Unedig  

  • Nodi, diffinio a dadansoddi materion a syniadau cymhleth, gan arfer barn feirniadol wrth werthuso ffynonellau gwybodaeth.  

  • Arddangos chwilfrydedd deallusol a cheisio meithrin gwybodaeth a dealltwriaeth. 

  • Ymchwilio i broblemau a chynnig datrysiadau effeithiol, myfyrio a dysgu o lwyddiannau a methiannau.  

  • Creu syniadau gwreiddiol a chymhwyso ffyrdd creadigol, llawn dychymyg a dyfeisgar o feddwl wrth ymateb i anghenion a phroblemau a nodwyd.  

  • Mynd ati’n bwrpasol i fyfyrio ar eu hastudiaethau eu hun, eu cyflawniadau a’u hunaniaeth  

  • Dangos gwydnwch, hyblygrwydd a chreadigrwydd i ddelio â heriau, a bod yn agored i newid.  

  • Adnabod a chyfleu eu sgiliau, eu gwybodaeth a’u dealltwriaeth eu hunain yn hyderus ac mewn amrywiaeth o gyd-destunau.  

  • Ystyried syniadau, cyfleoedd a thechnolegau newydd, gan adeiladu ar wybodaeth a phrofiad i wneud penderfyniadau gwybodus am eu dyfodol eu hunain. 

 

  

Rhinweddau Graddedigion – Asesiad:    

  

Gweithdy                   20% 

 

  • Nodi, diffinio a dadansoddi materion a syniadau cymhleth, gan arfer barn feirniadol wrth werthuso ffynonellau gwybodaeth. 

 

Arholiad                          80% 

 

  • Nodi, diffinio a dadansoddi materion a syniadau cymhleth, gan arfer barn feirniadol wrth werthuso ffynonellau gwybodaeth. 

 

Nodau Datblygu Cynaliadwy:      

   

Nid yw'r modiwl hwn yn cyd-fynd ag unrhyw un o'r nodau datblygu cynaliadwy, ond mae ei bynciau yn sail i bob un. 

How the module will be assessed

Asesiad ffurfiannol: Bydd y ddau weithdy cyntaf yn cael eu hasesu'n ffurfiannol, a chaiff adborth ei ddarparu naill ai ar lafar neu'n ysgrifenedig. Bydd hyn yn rhoi cyfle i fyfyrwyr atgyfnerthu cynnwys ffeithiol y modiwl ac ymarfer ei gymhwyso wrth ddatrys problemau. 

 

Asesiad crynodol: Bydd arholiad (80%) yn asesu'r deilliannau dysgu trwy ddatrys problemau a chyfrifiadau cemegol mecanyddol ac adeileddol. Dylid defnyddio perthnasedd y canlyniadau hyn i esbonio prosesau biolegol a dulliau dadansoddi cemegol. Bydd sgiliau chwilio ac adalw gwybodaeth yng nghyd-destun y deilliannau dysgu yn cael eu hasesu drwy ymarfer gweithdy (20%). 

 

Y CYFLE AR GYFER AILASESIAD YN Y MODIWL HWN: 

 

Cynhelir asesiadau pob modiwl sy’n cael ei ailsefyll yn y cyfnod Ailsefyll Arholiadau, sef cyn dechrau’r sesiwn academaidd ddilynol. 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Gweithdy crynodol N/A
Exam - Spring Semester 80 Cyflwyniad i Gemeg Bywyd 2

Syllabus content

Carbohydradau 

Strwythur siwgrau aldos a cetos. Mae pyranos a ffwranos yn ffurfio siwgrau, anomerau alffa a beta, a'r effaith anomerig. Cynrychiolaeth o garbohydradau fel amcanestyniadau Fischer, Haworth, "igam ogam" a Mills. Adeiledd glycosidau a'u hydrolysis cemegol ac ensymatig, profion ar gyfer rhydwytho siwgrau. 

Rolau adeileddol a signalu a chwaraeir gan garbohydradau mewn bioleg. 

 

Glycolysis 

Newidiadau egni rhydd Gibbs a rolau ATP wrth lywio adweithiau biocemegol yng nghyd-destun glycolysis. Rôl NAD+/NADH a cydffactorau eraill mewn adweithiau rhydocs. Adweithedd thioesterau ac adweithiau allweddol fel hydrolysis. 

Camau glycolysis a mecanweithiau'r trawsnewidiadau biolegol allweddol. 

 

Cylch Asid Citrig 

Synthesis asetyl CoA (cydensym A) gan y cymhlygyn pyrwfad dadhydrogenas a rôl thiamin pyroffosffad. 

Rhyngolynnau yn y cylch asid citrig a mecanweithiau'r trawsnewidiadau cemegol. Amlinelliad o'r gadwyn cludo electronau a synthesis ATP. 

 

Asidau Amino 

Strwythur a stereocemeg asidau amino alffa a ochr-gadwynau’r asidau amino proteinogenig. 

Grwpiau gweithredol ochr-gadwynau, polaredd, pKa a gwefr ar pH 7. 

Gallu ochr-gadwynau i ymgymryd â rhyngweithiadau (bondio hydrogen, rhyngweithiadau hydroffobig, bondio ïonig). 

 

Proteinau a Pheptidau 

Cyddwyso asidau amino i ddipeptidau, polypeptidau a phroteinau, ac (yn fyr) arwyddocâd biolegol y moleciwlau hyn a dadansoddi polypeptidau. 

Rôl thiamin pyroffosffad a ffosffad pyridocsal (PLP) ym miosynthesis asidau amino.  

 

 

Rhestr Darllen ac Adnoddau 

 

Lehninger Principles of Biochemistry, 8fed argraffiad, David L. Nelson a Michael M. Cox, W. H. Freeman, ISBN-13: 978-1-31-922800-2 

Organic Chemistry, 2il argraffiad, J Clayden, N Greeves, S Warren, Gwasg Prifysgol Rhydychen, 2012. ISBN-13: 978-0199270293 

Biochemistry, 9fed argraffiad, Jeremy M. Berg, John L. Tymoczko, Lubert Stryer, W. H. Freeman ISBN-13: 978-1-31-911465-7  

The Organic Chemistry of Biological Pathways, 2il argraffiad, J. E. McMurry, T. P. Begley, MacMillan, 2016. ISBN-13: 978-1-936221-56-1 

 


CH9995: Year of Study Abroad

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH9995
External Subject Code 100417
Number of Credits 120
Level L5
Language of Delivery English
Module Leader Dr Jonathan Bartley
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

 

The Year Abroad allows you to deepen and broaden your understanding of your degree subject by undertaking a research placement in a different country, approaching your research and understanding of the topic through other cultural and intellectual lenses.    

  

A year abroad may not only benefit and enrich your studies, but it also offers a significant personal and professional development opportunity: you will experience living in a different country and studying in a different culture, which may grow your confidence and independence, and many employers look for graduates with the wider experiences and intercultural sensitivity that a placement year abroad can provide. 

 

In addition to continuing to be a Cardiff University student, you will also be a member of your study abroad partner organisation. You will have access to the study abroad partners organisation’s support resources with all the benefits of working in a different country, approaching your studies through other cultural and intellectual lenses. 

 

Remember:  

While you are undertaking your Year of Study Abroad, you need to make sure you have completed the following: 

 

  • Enrolment at Cardiff: Confirmation of enrolment for your Cardiff University programme should be no later than 14 days after the start of study in any academic year in line with the requirements of Student Study and Engagement Regulations

  • Enrolment at the study abroad partner should be no later than four weeks after the commencement of your Year of Study Abroad.  

  • Communication with your school.  Keep in touch!  If you have any correspondence from your school, or requests to get in touch with them, it is really important you engage. After three unsuccessful requests from your school, the Overseas Placement Co-Ordinator or Head of School may start the Student Non-Engagement Procedure. 

 

On completion of the module a student should be able to

  • Gain a broader knowledge of your subject discipline(s) by acquiring an understanding of how the academic study of your subject(s) is organised and practiced at an institution outside the UK 

  • Demonstrate the ability to adapt to the academic practices of your subject specialism(s) in an institution outside the UK 

  • Carry out independent study and further develop self-study techniques.   

  • Gain personal skills that will enhance your employability.  

How the module will be delivered

 

You will undertake a research placement in a partner institution. Your placement will primarily consist of project work. You will work with a supervisor appointed by the partner organisation who will direct your project work.  

Skills that will be practised and developed

 

  • Independence, as you move to and take responsibility for your learning in a new cultural environment.   

  • Academic skills in applying new ways of thinking to your academic studies.   

  • Time management as you manage your own study programme.   

  • Self-reflexivity as you reflect on the benefits of studying abroad on your personal, intellectual, and professional development.   

  • Enhanced interpersonal skills as you adapt to a different social and/or cultural contexts, often where English is not the first language.   

  • Resilience in adapting to life and study in a new cultural environment   

 

Employability skills:     

This module is delivered and aligns with the following University Graduate Attributes:   

 

  1. Contribute positively and effectively when working in a team, having an impact from the outset. 

  1. Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities. 

  1. Be respectful of the roles of others and acknowledge the limits of their own skills/experience. 

  1. Listen to and take account of the views of others. 

  1. Communicate complex ideas effectively to diverse audiences. 

  1. Contribute to discussions, negotiate and present with impact. 

  1. Deliver, accept and act on constructive feedback.  

  1. Consider own personal and professional ethical, social and environmental responsibilities. 

  1. Demonstrate personal and professional integrity, reliability and competence. 

  1. Understand organisations, their stakeholders and their impact on the community. 

  1. Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  1. Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  1. Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  1. Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  1. Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  1. Understanding organisations, their stakeholders and their impact on the economy 

  1. Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  1. Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  1. Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future. 

 

Sustainable Development Goals:       

    

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

  • Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture  

  • Goal 3. Ensure healthy lives and promote well-being for all at all ages 

  • Goal 5. Achieve gender equality and empower all women and girls 

  • Goal 6. Ensure availability and sustainable management of water and sanitation for all 

  • Goal 12. Ensure sustainable consumption and production patterns 

 

How the module will be assessed

The opportunity for reassessment in this module: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.  

  

All resit assessments will be held in the first available Examination period after the Examining Board.  

  

Students who are permitted by the Examining Board to be reassessed in this module, will need to resubmit each failed component of the module (report, video presentation and/or placement review) during the next available Examination Period. 

Assessment Breakdown

Type % Title Duration(hrs)
Report 50 Report N/A
Presentation 20 Video Presentation N/A
Written Assessment 30 Placement Review N/A

CH9996: Industrial Training for Medicinal Chemists

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH9996
External Subject Code 100417
Number of Credits 120
Level L5
Language of Delivery English
Module Leader Dr Sankar Meenakshisundaram
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

BSc Medicinal Chemistry students on placement in industry are enrolled on this module during their year out. The Industrial Training for Medicinal Chemists module offers an opportunity for students to immerse themselves in the professional world, spending a year working within the pharmaceutical or wider chemical industries. This hands-on experience allows students to apply their academic knowledge in real-world settings, engaging in roles such as research and development, quality control, quality assurance, and analytical chemistry. Throughout the placement, students will develop their ability to contribute effectively within teams, build professional skills and work on real-world problems. This enhances employability by providing genuine work experience that boosts CVs to help stand out in the competitive graduate jobs market. 

 

On completion of the module a student should be able to

• Describe and present the objectives, methods and outcomes of an industrial placement in oral and written form.  

• Retrieve and communicate data, findings and procedures from a variety of sources.  

• Analyse a topic to give a discussion and critical assessment of the significant issues.  

• Devise and execute a complex plan of work towards a goal.  

• Analyse and interpret findings and use these to predict behaviour with which to inform future work.  

• Adapt to professional working practices in an industrial setting.  

• Contribute positively and effectively when working in a team. 

How the module will be delivered

Students take this module whilst undertaking a placement in industry, of minimum 9 month duration.  It consists primarily of work supervised by the placement provider. The work is described in a Written report, Video presentation and Placement review.  

 

Skills that will be practised and developed

ntellectual skills 

• Identify, define and analyse complex issues and ideas, exercising critical judgement in evaluating sources of information  

• Analysis of an advanced topic, discussion and critical assessment of the significant issues;  

• Planning, and executing a complex activity;  

 

Chemistry-specific skills 

• Searching and selecting from the literature, discussing it critically in the context of the work undertaken;  

• Conducting extended work at a chemical sciences-using placement provider;  

• Recording of all working notes in an appropriate manner with reference to risk and hazard information where applicable;  

 

Transferable skills 

• Communicate complex ideas effectively to diverse audiences;   

• Organisation and presentation of oral and written reports;  

• Adapt to working in an unfamiliar culture;  

• Learn from others in a work-based environment  

 

 

 

Employability skills:     

This module is delivered and aligns with the following University Graduate Attributes:   

 

  1. Contribute positively and effectively when working in a team, having an impact from the outset. 

  1. Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities. 

  1. Be respectful of the roles of others and acknowledge the limits of their own skills/experience. 

  1. Listen to and take account of the views of others. 

  1. Communicate complex ideas effectively to diverse audiences. 

  1. Contribute to discussions, negotiate and present with impact. 

  1. Deliver, accept and act on constructive feedback.  

  1. Demonstrate personal and professional integrity, reliability and competence. 

  1. Understand organisations, their stakeholders and their impact on the community. 

  1. Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  1. Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  1. Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  1. Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  1. Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  1. Understanding organisations, their stakeholders and their impact on the economy 

  1. Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  1. Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  1. Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future. 

 

 

Sustainable Development Goals:       

    

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

  • Goal 3. Ensure healthy lives and promote well-being for all at all ages 

  • Goal 8. Promote sustained, inclusive and sustainable economic growth, full and productive employment and decent work for all 

 

How the module will be assessed

The module will be assessed via coursework including a written report, a video presentation, and an essay reviewing the placement.  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the first available Examination period after the Examining Board. 

 

Students who are permitted by the Examining Board to be reassessed in this module, will need to resubmit each failed component of the module (report, video presentation and/or placement review) during the next available Examination Period.  

Assessment Breakdown

Type % Title Duration(hrs)
Presentation 20 Video Presentation N/A
Written Assessment 30 Placement Review N/A
Report 50 Written Report N/A

Syllabus content

The placement experience will be undertaken in the industrial host approved by the placement scheme coordinator. This will be carried out on a time scale appropriate for the particular placement, but is expected to take about 1200 hours of student time, including all literature work, project work, preparation of presentation and written report. 

 

The placement must provide opportunities for independent thought and project work although it is recognised that the nature of the host’s work may require students to undertake directed work related to the host’s business. 

 

The main report will be supplemented by a short placement review, describing the particular environment of the placement - aspects of cultural differences in the host institution, skills development during the placement and business aspects of the company.  

 

Regular contact will be maintained throughout, primarily through the personal tutor, with involvement by the placement coordinator as necessary.   


CH9998: Placement Year Abroad

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH9998
External Subject Code 100417
Number of Credits 120
Level L5
Language of Delivery English
Module Leader Dr Jonathan Bartley
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

BSc students on placement overseas are enrolled on this module.  

 

It consists of a substantial project on a chemical sciences topic conducted at an overseas placement provider.  

 

You will submit a written report and video that discusses your placement experience.  

 

These will be supplemented by a placement review which provides a reflective account of skills development over the course of the placement.  

 

Satisfactory performance is required for the award of the degree, and the mark awarded contributes 10% to the overall degree classification. 

 

On completion of the module a student should be able to

  • Describe and present the objectives, methods, and outcomes of a project in oral and written form. 

  • Retrieve and communicate data, findings, and procedures from a variety of sources. 

  • Analyse a topic to give a discussion and critical assessment of the significant issues. 

  • Devise and execute a complex plan of work towards a goal. 

  • Adapt to professional working practices in an industrial or overseas setting. 

  • Contribute positively and effectively when working in a team. 

How the module will be delivered

Students undertake a placement in a partner institution overseas, of 9 - 12 months duration.  

 

It consists primarily of project work supervised by a staff member at the placement provider.  

 

The project results are presented in a written report, Video presentation and Placement review. 

Skills that will be practised and developed

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Graduate Attributes – Assessment:    

  

 Coursework - Report                  

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 Coursework – Video Presentation 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 Coursework – Placement Review     50% 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

Goal 4. Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, and decent work for all

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

 

 

How the module will be assessed

The module will be assessed via coursework including a written report of the project, a video presentation in which you discuss the background to your project, your own role and findings, and an essay reviewing the placement. The placement review is a reflective commentary that should demonstrate skills development and an appreciation of the culture and working practices at the overseas placement provider and how these differ from the UK. 

 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the first available Examination period after the Examining Board. 

 

Students who are permitted by the Examining Board to be reassessed in this module, will need to resubmit each failed component of the module (report, video presentation and/or placement review) during the next available Examination Period. 

Assessment Breakdown

Type % Title Duration(hrs)
Presentation 20 Video presentation N/A
Report 50 Placement Year Abroad- Written Report N/A
Report 30 Placement Year Abroad- Placement Review N/A

Syllabus content

The placement experience will be undertaken in the academic host approved by the placement scheme coordinator.  

 

The main feature will be a substantial project on a chemical sciences topic determined by the host.  

 

This will be carried out on a time scale appropriate for the particular placement but is expected to take about 1200 hours of your time, including all literature work, project work, preparation of presentation and written report.  

 

The main report will be supplemented by a short placement review, describing the particular environment of the placement - aspects of cultural differences in the host institution and skills development during the placement. 

 

Regular contact will be maintained throughout, primarily through the personal tutor, with involvement by the placement coordinator, as necessary. 


CH9999: Industrial Training

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH9999
External Subject Code 100417
Number of Credits 120
Level L5
Language of Delivery English
Module Leader Dr Sankar Meenakshisundaram
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

BSc Chemistry students on placement in industry are enrolled on this module during their year out. The Industrial Training module offers an opportunity for students to immerse themselves in the professional world, spending a year working in industry. This hands-on experience allows students to apply their academic knowledge in real-world industrial settings, engaging in a wide range of roles such as research and development, quality management, analysis, communications, finance or IT. Throughout the placement, students will develop their ability to contribute effectively within teams, build professional skills and work on real-world problems. This enhances employability by providing genuine work experience that boosts CVs to help stand out in the competitive graduate jobs market. 

 

Satisfactory performance is required for the award of the degree, and the mark awarded contributes 10% to the overall degree classification.  

On completion of the module a student should be able to

 

  • Describe and present the objectives, methods, and outcomes of a project in oral and written form.  

  • Retrieve and communicate data, findings, and procedures from a variety of sources.  

  • Analyse a topic to give a discussion and critical assessment of the significant issues.  

  • Devise and execute a complex plan of work towards a goal.  

  • Adapt to professional working practices in an industrial or overseas setting.  

  • Contribute positively and effectively when working in a team. 

How the module will be delivered

 

Students take this module whilst undertaking a placement industry, of minimum 9-month duration.   

 

It consists primarily of project work supervised by the placement provider.  

 

The project results are presented in a written report, Video presentation and Placement review.  

 

Skills that will be practised and developed

Intellectual skills: 

 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgement in evaluating sources of information  

  • Analysis of an advanced topic, discussion, and critical assessment of the significant issues;  

  • Planning, and executing a complex activity;  

 

Chemistry-Specific Skills:  

 

  • Searching and selecting from the literature, discussing it critically in the context of the project undertaken;  

  • Conducting an extended project at a chemical sciences-using placement provider;  

  • Recording of all working notes in an appropriate manner with reference to risk and hazard information where applicable;  

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

Graduate Attributes – Assessment:    

  

 Coursework – Video Presentation 

  • Communicate complex ideas effectively to diverse audiences.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

 

 Coursework – Placement Review 

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

 

 Coursework – Report 

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact. 

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion 

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

Goal 4. Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all 

Goal 6. Ensure availability and sustainable management of water and sanitation for all 

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, and decent work for all  

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

 

How the module will be assessed

The module will be assessed via coursework including a written report, a video presentation of the project, and an essay reviewing the placement.  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.  

 

All resit assessments will be held in the first available Examination period after the Examining Board.  

 

Students who are permitted by the Examining Board to be reassessed in this module, will need to resubmit each failed component of the module (report, video presentation and/or placement review) during the next available Examination Period.  

Assessment Breakdown

Type % Title Duration(hrs)
Report 50 Written Report N/A
Presentation 20 Video Presentation N/A
Report 30 Placement Review N/A

Syllabus content

The placement experience will be undertaken in the industrial host approved by the placement scheme coordinator.  

 

The main feature will be a substantial project on a chemical sciences topic determined by the host.  

 

This will be carried out on a time scale appropriate for the placement but is expected to take about 1200 hours of your time, including all literature work, project work, preparation of presentation and written report.  

 

For the placements, it is expected that all of the nominal 1200 hours will be spent on the project at the host, but it is recognised that the nature of the host’s work may require this to be modified and directed work related to the host’s business may take up some of the time, though a substantial independent and original project must be included.  

 

The main report will be supplemented by a short placement review, describing the environment of the placement - aspects of cultural differences in the host institution, skills development during the placement and business aspects of the company.  

 

Regular contact will be maintained throughout, primarily through the personal tutor, with involvement by the placement coordinator, as necessary. 


CH2301: Training in Research Methods

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH2301
External Subject Code 100417
Number of Credits 20
Level L6
Language of Delivery English
Module Leader Dr Jonathan Bartley
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This is a module of practical work, designed to familiarise learners with advanced research techniques used for experiments of a synthetic and/or instrumental nature, and with professional applications of information technology. 

 

The module will also include exercises designed to develop critical analysis, problem-solving, oral, and written communication, and to enhance your employability. 

On completion of the module a student should be able to

  • Use equipment appropriate to the experiments in a safe and correct way; 

  • Obtain and act upon safety and hazard information for chemicals and chemical procedures; 

  • Recognise the relationship between spectroscopic properties (NMR, IR, UV/vis and XPS) and molecular structure and symmetry; 

  • Critically assess the experimental results in relation to the chemical principle behind each experiment; 

  • Write a concise report on all results obtained; 

  • Critically review primary literature chemistry articles.  

How the module will be delivered

Approximatively 60 hours (20 x 3 hours) laboratory classes, plus approximatively 6 hours of seminars / workshops. 

 

You will undertake several tasks in synthetic, instrumental and computer laboratory. For each one, performance in the laboratory and understanding of underlying concepts will be tested by one or more written report, submission of samples and spectra, or online tests.  

Skills that will be practised and developed

Intellectual skills: 

 

  • You will be able to draw conclusions about reaction mechanisms by combining experimental and spectroscopic data, developing analytical and critical thinking skills 

  • You will be developing the ability to relate the experimental data to the underlying theory enhancing your critical thinking skills  

  • You will analyse problems and identify the critical decisions needed in designing approaches to solutions, developing problem solving skills 

 

Chemistry-specific skills: 

 

You will develop skills in: 

 

  • Preparing, isolating, and purifying organic and inorganic compounds using standard procedures; 

  • Manipulating air-sensitive compounds under an inert atmosphere; 

  • Preparing and isolating aqueous coordination compounds; 

  • Obtaining and interpreting IR and UV/vis spectra of organic and transition-metal compounds; 

  • Interpreting IR and NMR spectra of organic compounds and hence critically assess the outcome of a reaction; 

  • Determining kinetic of reaction and reaction mechanism by interpreting experimental data;  

  • Using experimental data to calculate an unknown value; 

  • Assessing the risks associated with the use of chemicals and apparatus for themselves, the others, and the environment, which will help developing awareness of health and safety along with ethical, social, and environmental responsibilities; 

  • Recording experimental data in an organised manner and presenting a written report and oral discussion clearly and concisely, developing the ability to effectively communicate results; 

  • Determining the most appropriate format for presentation of experimental data acquiring impactful presentation skills; 

  • Showing scientific judgement and ability to select appropriate experiments to tackle a problem developing problem solving, analytical and independent critical thinking skills. 

  • Reviewing primary literature chemistry articles, developing the ability to exercise critical judgement in evaluating literature sources 

 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:  

   

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.   

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Graduate Attributes – Assessment:    

  

Written Assessment                10% 

 

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback. 

  • Consider own personal and professional ethical, social, and environmental responsibilities. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

Practical Assessment              90% 

 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Listen to and take account of the views of others. 

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback. 

  • Consider own personal and professional ethical, social, and environmental responsibilities. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path. 

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development 

How the module will be assessed

Formative assessment: an online test, consisting of numerical and multiple-choice answers, will be assessed formatively and will help you to ensure that you are performing and interpreting calculations correctly for the applications of information technology part of the module. 

Summative assessment: The learning outcomes will be assessed continuously on the basis of written reports, samples of compounds prepared, spectroscopic and analytical data, performance in the laboratory. Consistent attendance of practical sessions is essential.  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.  

 

Practical work cannot be repeated after the scheduled time for the module is over. Reassessment involves completing the written assessments based on the student’s own data.  

 

Students who need to repeat or do the laboratory work will be required to resit as an internal student in the next academic session.  

Assessment Breakdown

Type % Title Duration(hrs)
Practical Skills Assessment 10 Key Skills N/A
Report 25 Inorganic Report N/A
Report 25 Organic Report N/A
Report 25 Physical Report N/A
Written Assessment 15 Molecular Modelling N/A

Syllabus content

Synthetic chemistry will include the preparation of a range of compounds on small and medium scale. Reactions will involve organic, organometallic and coordination compounds, manipulation of air-sensitive compounds, and characterisation and analysis using NMR, IR, UV, and other techniques as appropriate. 

 

Physical chemistry will involve accurate measurement of physical properties and recording, interpreting, and using experimental data to calculate an unknown value.  

 

Application of information technology in chemistry – application of theoretical methods and calculations to probe molecular structure, bonding, and reactivity.  

 

Key Skills - critical analysis of the primary chemical literature 


CH2306: Application of Research Methods

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH2306
External Subject Code 100417
Number of Credits 20
Level L6
Language of Delivery English
Module Leader PROFESSOR Philip Davies
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module of practical work develops and applies principles and techniques learnt in CH2301.  

 

New experimental techniques appropriate to synthetic and instrumental projects will be explored and the relationship between theory and experiment will be illustrated in a number of practically based problem-solving exercises.  

 

As part of the general skills theme this module also involves a group project in which you will work in teams to address aspects of a particular chemical problem.  

 

The teams write technical reports on their work and present the data to the whole class in a group discussion.  

 

Finally, you will write an individual paper in the RSC Chemical Communications format presenting the findings from the class experiment.  

 

The skills learned in this module are linked to several of the Cardiff Graduate attributes, including being Collaborative, Effective Communicators and Independent and Critical Thinkers  

On completion of the module a student should be able to

  • Use equipment appropriate to the experiments in a safe and correct way; 

  • Obtain and act upon safety and hazard information for chemicals. 

  • Suggest an appropriate experimental strategy to investigate a problem 

  • Work with a team to create a group report and presentation 

  • Write a scientific paper based on a number of different data sets.  

 

How the module will be delivered

This practical module consists of short mini-research tasks covering the areas of both synthetic and instrumental chemistry.  

In the synthetic laboratory, you will typically undertake five or six practical tasks and for each one, submit a literature survey and a report on your own experimental results.  

 

For the instrumental section, you will work in small teams to investigate a specific problem set for the class, using cutting edge equipment based in research laboratories. Each team reports their findings to the class in the form of a report and presentation. You will then, individually, write up the class findings as a scientific paper.  

 

Skills that will be practised and developed

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.   

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

Graduate Attributes – Assessment:    

Practical Assessment                       100% 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate, and present with impact. 

  • Deliver, accept, and act on constructive feedback.  

  • Consider own personal and professional ethical, social, and environmental responsibilities. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture 

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, and decent work for all  

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

Goal 12. Ensure sustainable consumption and production patterns  

Goal 13. Take urgent action to combat climate change and its impacts 

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development 

How the module will be assessed

This module will be assessed continuously on the basis of written reports, samples of compounds prepared, spectroscopic and analytical data, and performance in the laboratory.  

 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

Practical work cannot be repeated after the scheduled time for the module is over. Reassessment for the module will therefore involve completing the written assessments based, either on the student’s own data or on data supplied for the experiments. 

Assessment Breakdown

Type % Title Duration(hrs)
Report 33 Inorganic Report N/A
Report 33 Organic Report N/A
Report 34 Physical Report N/A

Syllabus content

This practical module introduces some new skills in synthetic chemistry and requires you to plan and execute the synthesis of target materials.  

 

The physical chemistry section of the module is a class project, which involves applying knowledge from previous modules to interpret data from a number of advanced spectroscopic and microscopic methods and working as a team to develop a model to account for the experimental data.

 


CH2325: Project

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH2325
External Subject Code 100417
Number of Credits 20
Level L6
Language of Delivery English
Module Leader Dr Athanasia Dervisi
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module consists of a supervised research project for visiting students. This may be in any area of practical or theoretical chemistry. Visiting students need to have secured a supervisor before enrolment in the module. The project is completed by a written report. 

On completion of the module a student should be able to

• Describe and present the objectives, methods and outcomes of a project. 

• Retrieve and communicate data, findings and procedures from a variety of sources. 

• Analyse a topic to give a discussion and critical assessment of the significant issues. 

• Devise and execute a complex plan of work towards a goal. 

• Analyse and interpret findings and use these to predict behaviour with which to inform future work. 

• Contribute positively and effectively when working in a team. 

How the module will be delivered

Visiting students take this module whilst undertaking a placement in Cardiff University.  It consists primarily of project work supervised by the placement supervisor.  The results are presented in a written report. 

Skills that will be practised and developed

Intellectual skills 

  1. Identify, define and analyse complex issues and ideas, exercising critical judgement in evaluating sources of information

  2. Analysis of an advanced topic, discussion and critical assessment of the significant issues; 

  3. planning, and executing a complex activity; 

Chemistry-specific skills 

  1. searching and selecting from the literature, discussing it critically in the context of the project undertaken;

  2. recording of all working notes in an appropriate manner with reference to risk and hazard information where applicable; 

Transferable skills 

  1. Communicate complex ideas effectively to diverse audiences;  

  2. Organisation and presentation of oral and written reports; 

  3. Adapt to working in an unfamiliar culture; 

  4. Learn from others in a research-based environment 

 

How the module will be assessed

The module will be assessed via coursework including a written report. 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

All resit assessments will be held in the first available Examination period after the Examining Board. 

Reassessment will consist of a further attempt at report, depending on those parts that contributed to failure on original submission. It will not normally be possible to extend or repeat experimental work as part of reassessment. 

Assessment Breakdown

Type % Title Duration(hrs)
Project 100 Report N/A

Syllabus content

This module consists of a supervised research project for visiting students. This may be in any area of practical or theoretical chemistry. Students prepare a written report based on their results. This is marked by the project supervisor.   


CH2325: Project

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH2325
External Subject Code 100417
Number of Credits 20
Level L6
Language of Delivery English
Module Leader Dr Athanasia Dervisi
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module consists of a supervised research project for visiting students. This may be in any area of practical or theoretical chemistry. Visiting students need to have secured a supervisor before enrolment in the module. The project is completed by a written report. 

On completion of the module a student should be able to

• Describe and present the objectives, methods and outcomes of a project. 

• Retrieve and communicate data, findings and procedures from a variety of sources. 

• Analyse a topic to give a discussion and critical assessment of the significant issues. 

• Devise and execute a complex plan of work towards a goal. 

• Analyse and interpret findings and use these to predict behaviour with which to inform future work. 

• Contribute positively and effectively when working in a team. 

How the module will be delivered

Visiting students take this module whilst undertaking a placement in Cardiff University.  It consists primarily of project work supervised by the placement supervisor.  The results are presented in a written report. 

Skills that will be practised and developed

Intellectual skills 

  1. Identify, define and analyse complex issues and ideas, exercising critical judgement in evaluating sources of information

  2. Analysis of an advanced topic, discussion and critical assessment of the significant issues; 

  3. planning, and executing a complex activity; 

Chemistry-specific skills 

  1. searching and selecting from the literature, discussing it critically in the context of the project undertaken;

  2. recording of all working notes in an appropriate manner with reference to risk and hazard information where applicable; 

Transferable skills 

  1. Communicate complex ideas effectively to diverse audiences;  

  2. Organisation and presentation of oral and written reports; 

  3. Adapt to working in an unfamiliar culture; 

  4. Learn from others in a research-based environment 

 

How the module will be assessed

The module will be assessed via coursework including a written report. 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

All resit assessments will be held in the first available Examination period after the Examining Board. 

Reassessment will consist of a further attempt at report, depending on those parts that contributed to failure on original submission. It will not normally be possible to extend or repeat experimental work as part of reassessment. 

Assessment Breakdown

Type % Title Duration(hrs)
Project 100 Report N/A

Syllabus content

This module consists of a supervised research project for visiting students. This may be in any area of practical or theoretical chemistry. Students prepare a written report based on their results. This is marked by the project supervisor.   


CH3307: Advanced Spectroscopy and Diffraction

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH3307
External Subject Code 100417
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Professor Kenneth Harris
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

The module explains how detailed information about structure, stereochemistry, and the behaviour of chemical species in solution and in the solid state can be obtained by using luminescence spectroscopy, electron paramagnetic resonance (EPR) spectroscopy, and diffraction techniques (specifically X-ray diffraction, neutron diffraction and electron diffraction, as well as electron microscopy). 

On completion of the module a student should be able to

Luminescence Spectroscopy  

 

  • Describe the fundamental principles of photoluminescence spectroscopy and the different types of electronically excited states associated with organic molecules and inorganic d- and f-block coordination complexes.       

  • Sketch Jablonski energy level diagrams for different classes of compound and apply knowledge of photoexcited state molecules to various applications.   

 

EPR Spectroscopy 

   

  • Sketch energy level diagrams for electron-nuclear spin systems and predict the appearance of EPR spectra of organic radicals, including the multiplicity of resonance lines.   

  • Extract spin Hamiltonian values from experimental spectra and correlate with chemical structure.   

 

Diffraction Techniques  

   

  • Explain the scope and limitations of X-ray diffraction, neutron diffraction, electron diffraction and electron microscopy techniques in the study of structural properties of solids.   

  • Formulate the optimum experimental strategy for exploring specific aspects of solid-state structure.  

 

How the module will be delivered

21 Lectures, with seven lectures allocated to each of the three components of the module (Luminescence Spectroscopy, EPR Spectroscopy and Diffraction Techniques). Each lecture is held “in person” in a lecture theatre. The duration of each lecture is 50 minutes. Each lecture is recorded, with the recording made available to students on Learning Central on the same day as the lecture.   

 

Three Formative Workshops, with one formative workshop allocated to each of the three components of the module (Luminescence Spectroscopy, EPR Spectroscopy and Diffraction Techniques). The duration of each formative workshop is 50 minutes. Each formative workshop is held as a whole-class activity in a lecture theatre. Each formative workshop is recorded, with the recording made available to students on Learning Central on the same day as the workshop.   

Skills that will be practised and developed

Academic skills:  

 

  • You will develop the necessary skills to identify the appropriate experimental methods (or combination of experimental methods) to use in answering specific problems in chemistry, within the context of the range of experimental techniques covered in the lecture course.  

 

  • As an example, some of the typical problems posed in formative and summative workshops will rely on utilizing knowledge of the scope and limitations of the different experimental techniques covered in the lecture course in order to decide the most appropriate experimental strategy for establishing a specific type of information about a molecule, a radical or a solid material.  

 

  • These skills will contribute to your development of independent and critical thinking skills.  

 

 

Chemistry-Specific Skills:  

 

  • Interpretation and analysis of photophysical spectra and/or data, and correlation with molecular structure.   

 

  • Interpretation of EPR spectra for paramagnetic species in solution.   

 

  • Analysis of experimental data and correlation with chemical structure.   

 

  • Formulating optimum experimental strategies (involving the use of one or more of the X-ray diffraction, neutron diffraction, electron diffraction and electron microscopy techniques) for exploring specific aspects of solid-state structure.   

 

  • Ability to select appropriate techniques for determination of structure in solution or in the solid state for a range of chemical situations, and to assess the advantages/disadvantages of each technique for tackling specific structural problems.   

 

Employability skills:     

   

This module is delivered and aligns with the following University Graduate Attributes:     

   

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

   

Graduate Attributes – Assessment:    

  

Assessed Workshop 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Exam 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

Goal 3. Ensure healthy lives and promote well-being for all at all ages

Goal 7. Ensure access to affordable, reliable, sustainable, and modern energy for all

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

How the module will be assessed

Written Examination   

 

There is one written examination representing 80% of the total module mark.   

 

Format of Assessment: You will attend an “in-person” written examination held in an examination hall at a scheduled date/time within the Spring Examination Period. The exam paper contains four questions, and you are required to answer three questions. Each of the four questions comprises two half-questions from different components of the module.   

 

Duration of Assessment: The time allowed for you to complete the written examination is 2 hours.   

 

Assessment Criteria: The maximum number of marks allocated to each question is indicated on the exam paper. You will be given a mark between zero and the maximum mark depending on the quality of your written answer.   

 

Pass Mark: The written examination contributes 80% of the total module mark. The pass mark for the module is based on the total mark awarded for the module (i.e., the combined mark of the written examination and the assessed workshop) and is 40%.   

 

Assessed (Summative) Workshop   

 

There is one assessed (summative) workshop representing 20% of the total module mark.   

 

Format of Assessment: You are required to tackle a problem sheet containing an equal weighting of questions from each of the three components of the module, and to submit your written answers against a specified deadline. You are typically given 7 weeks between the release of the problem sheet and the deadline for submission of your written answers. The submission deadline is typically 3 weeks after the completion of all lectures and formative workshops associated with the module.   

 

Assessment Criteria: The maximum number of marks allocated to each question is indicated on the problem sheet. You will be given a mark between zero and the maximum mark depending on the quality of your written answer.   

 

Pass Mark: The assessed workshop contributes 20% of the total module mark. The pass mark for the module is based on the total mark awarded for the module (i.e., the combined mark of the written examination and the assessed workshop) and is 40%.   

 

Resit Examination   

 

For students who fail the overall module based on the total mark awarded for the module (i.e., the combined mark of the written examination and the assessed workshop), a resit examination is available. The format of the resit examination is the same as the written examination described above, except that the resit examination is held at a scheduled date/time within the Resit Examination Period.  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.  

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session. 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Assessed Workshop N/A
Exam - Spring Semester 80 Advanced Spectroscopy and Diffraction 2

Syllabus content

Luminescence Spectroscopy   

Fundamentals, Jablonski diagrams. Instrumentation and data acquisition. Stokes’ shift, quantum yield, lifetimes. Fluorescence versus phosphorescence. Radiative and non-radiative decay and contributions. Energy gap law. Types of organic chromophores, effects of structure on emission. Luminescent transition metal coordination complexes. Luminescent trivalent lanthanide complexes.   

 

EPR Spectroscopy   

Basic principles of Electron Paramagnetic Resonance (EPR). Origin and significance of the electron Zeeman and nuclear Zeeman effects. Derivation of simple spin Hamiltonian for system containing spin-active nuclei. Applications of EPR to characterize paramagnetic systems. Analysis and interpretation of EPR spectra of organic radicals and main group radicals, including determination of spin Hamiltonian parameters [g and A (hyperfine) values].   

 

Diffraction Techniques   

Fundamentals: Properties of X-rays. Properties of electron beams. Properties of neutron beams. Production of X-rays (conventional sources and synchrotron radiation). Fundamentals of diffraction by crystalline solids.   

 

Applications, Scope, and Limitations of Techniques: X-Ray diffraction (XRD): applications of X-ray diffraction, single crystal versus powder X-ray diffraction, advantages of using synchrotron radiation, limitations of X-ray diffraction. Neutron diffraction (ND): applications of neutron diffraction, neutron diffraction versus X-ray diffraction. Electron diffraction and electron microscopy: electron diffraction (ED), transmission electron microscopy (TEM), scanning electron microscopy (SEM), low energy electron diffraction (LEED).   


CH3308: Bioinorganic Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH3308
External Subject Code 101043
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Professor Ian Fallis
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

Many key processes in biology are enabled by metal ions such as calcium, iron, copper, and zinc. In this module the biological functions of a wide range of elements are examined with a particular focus upon the functions of metal ions and their catalytic roles in biology.  

 

The module will correlate the fundamental coordination chemistry of metal ions to the wide range of redox, Lewis acidic and structural roles they play in biological structures. The roles of metal ions in selected important drugs will also be explored.  

 

On completion of the module a student should be able to

  • Describe the range of functions of metal ions in biological systems.  

  • Classify metalloenzymes by reaction type and illustrate with relevant examples.  

  • Classify the types of metalloproteins and co-factors that incorporate transition metal and main group ions.  

  • Understand from an evolutionary perspective the need for transition metal ions in biological systems.  

  • Explain the mechanisms of metalloenzyme promoted chemical transformations.  

  • Identify and illustrate the mode of action of metal containing drugs.  

How the module will be delivered

A blend of on-line learning activities with face-to-face small group learning support and feedback. 

Content will be delivered primarily using lectures (22 hour across one semester, equating to two lectures per week). In addition, lectures will include worked problems and informal ad hoc formative tests. 

This will address the learning outcomes, while examples presented will show you how you may also demonstrate your achievement. 

Workshops (3 x 1 hour, one formative, two summative) will be used to enhance and assess the basic knowledge from the lecture material. 

Tutorials (2 x 1 hour, formative) will allow tutors to monitor and guide your progress in meeting all learning outcomes. 

Skills that will be practised and developed

Chemistry-Specific Skills: 

 

  • Classification of complex bioinorganic systems.  

  • Analysis and understanding of the mechanisms in bioinorganic chemical systems;  

  • Correlation of fundamental chemical properties of the elements with their roles in biological systems.  

 

Employability skills: 

 

This module is delivered and aligns with the following University Graduate Attributes: 

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 

Graduate Attributes – Assessment:    

  

 Written Assessment 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgement in evaluating sources of information.  

  • Actively reflect on own studies, achievements, and self-identity  

 

 Exam 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgement in evaluating sources of information.  

  • Actively reflect on own studies, achievements, and self-identity  

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 3. Ensure healthy lives and promote well-being for all at all ages  

Goal 15. Protect, restore, and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss

How the module will be assessed

Formative and Summative Assessment: The three workshops take the form of multiple-choice tests to be taken in the class. Two will be assessed summatively, and feedback provided during the workshop. Tutorials will be used as reading periods to allow you to absorb course material and raise questions.  

Summative assessment: A written exam (2 h) will test your ability to demonstrate your knowledge and understanding of the syllabus content, and their ability to apply the techniques/concepts covered to unseen problems. The coursework will allow you to demonstrate ability to use electronic and printed resources to locate and understand relevant information. Marks will reflect the extent you have met the module learning outcomes shown above.  

  

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.  

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session.  

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Workshops N/A
Exam - Spring Semester 80 Bioinorganic Chemistry 2

Syllabus content

The placement experience will be undertaken in the industrial or university host approved by the placement scheme coordinator.  

 

The main feature will be a substantial project on a chemical sciences topic determined by the host. This will be carried out on a time scale appropriate for the particular placement but is expected to take about 800 hours of your time, including all literature work, project work, preparation of presentation and written report.  

 

For academic placements, it is expected that all of the nominal 800 hours will be spent on the project at the host.  

 

For the industrial placements, the aim is for a similar arrangement, but it is recognised that the nature of the host’s work may require this to be modified and directed work related to the host’s business may take up some of the time, though a substantial independent and original project must be included.  

 

The main report will be supplemented by a short placement review, describing the particular environment of the placement - aspects of cultural differences in teaching and learning methods in host university, skills development during the placement, business aspects of the company for industrial placements.  

 

Regular contact will be maintained throughout, primarily through the personal tutor, with involvement by the placement coordinator, as necessary.  


CH3310: Heterogeneous Catalysis

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH3310
External Subject Code 100417
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Professor Stuart Taylor
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module will provide insight into the importance of heterogeneous catalysis in the modern world, and it will allow you to learn how it is applied for societal benefit.  

 

It will demonstrate the diverse applications of heterogeneous catalysis and its importance to both the modern chemical industry and protecting the environment.  

 

It will outline the essential fundamental concepts and methodologies available for studying these processes, as well as showing you molecular level mechanisms and principals involved in catalysis.   

 

 Processes covered include oxidation reactions, car exhaust treatment, reducing NOx emissions from stationary sources, and acid-catalysed reactions.  

 

The importance of heterogeneous catalysts and their applications in environmental applications and sustainability will be outlined and addressed.  

 

For particular applications, examples of several types of catalysts, including supported metals, metal oxides, and zeolites, will all be presented and discussed.   

 

We will cover key details and catalyst characteristics, as well as the typical attributes and preparation of a heterogeneous catalyst.  

 

We will assess a catalyst's performance, provide quantitative descriptors, and discuss catalyst deactivation processes.   

 

We will examine heterogeneous catalyst mechanisms and contrast the various models.  

 

The Langmuir-Hinshelwood, Eley-Rideal, and Mars van Krevelen mechanisms will be addressed, and experimental methods used to identify mechanism will be covered.   

 

We will approach the specifics of how heterogeneous catalysts are utilised in various reactor types, covering both laboratory and industrial scales.  

 

The various physical forms of the catalysts will also be taken into account in the context of various reactors and performance optimization.  

On completion of the module a student should be able to

On successful completion of the module, you should be able to:  

 

  • Describe the fundamental principles and mechanisms of heterogeneous catalysts and outline how they are applied to a range of reactions used in modern industrial processes, new sustainable processes, and environmental protection.   

 

  • Evaluate experimental data from performance of heterogeneous catalysts and relate this to key catalyst characteristics to establish an understanding between structure, composition, and chemistry.   

 

  • Propose mechanisms for heterogeneously catalysed transformations covering a wide range of chemistry and recommend appropriate experimental methodology to establish the mechanism.   

 

  • Apply concepts of heterogeneous catalysis to propose catalysts and key functionality that are required to catalyse a specific reaction, which may be related to presented examples or an unseen transformation.   

 

  • Examine critically a catalytic process that is currently operated at scale, based on analysis of information from the literature prioritise the key findings to summarise factors that make the process successful.  

How the module will be delivered

 

You will receive course content delivered primarily using face to face lectures.  

 

The course consists of 22 lectures across the Spring semester, with approximately 2 lectures each week.   

 

Lectures may include some worked problems and informal formative questions to support principles introduced.  

 

These will help you to address the learning outcomes and provide opportunities to apply knowledge and develop understanding.    

 

The lecture schedule will follow the module map published prior to the start of the module. Lectures will be recorded and will be available following the live sessions.  

 

A combination of lecture slides and additional supporting notes will be available for you prior to the face-to-face lectures.    

 

Lecture material will be supported by three workshops. Two workshops will be formative and will take the form of face-to-face sessions, and these will focus on supporting problem solving based on material from lectures.  

 

A single summative workshop will focus on research into a self-selected industrial catalytic process, and you will attempt this over a timescale of several weeks using independent study.  

 

You will be required to submit a one-page critical narrative summary for assessment.  

 

Skills that will be practised and developed

Skills developed through formal module learning outcomes and summative assessment are:  

 

Academic skills: 

 

  • The module develops a number of your transferable skills, such as problem solving, numeracy, information searching and critical analysis of information, all of which are important for enhancing employability.   

 

  •  Through the summative assessment exercise, you will be able to demonstrate ability to research a new area of catalysis to you, and critically assess and prioritise information so it can be communicated precisely and effectively.  

 

  • The formative assessments will allow for collaborative working when discussing concepts and their application to problem solving.  

 

Chemistry-Specific Skills:  

 

  • You will develop chemistry specific skills, some aspects will focus on applying ideas introduced in earlier modules, these will include kinetics, thermodynamics, solid state chemistry and surface chemistry, along with some new ones.  

 

  • You will apply these fundamental concepts to understand heterogeneous catalysts and how they operate. Application of these fundamental principles will reinforce your skills in application to critical problem solving and understanding.  

 

  • Developing these skills in the principles of heterogeneous catalysis will allow you to start to select appropriate catalysts for specific target reactions and appreciate how catalysts could be applied to solve pressing issues around sustainability, reaching net zero carbon targets and tackling environmental challenges.   

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:   

  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Graduate Attributes – Assessment:    

  

 Written Report 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Deliver, accept, and act on constructive feedback.  

  • Consider own personal and professional ethical, social, and environmental responsibilities. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 Exam 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Deliver, accept, and act on constructive feedback.  

  • Consider own personal and professional ethical, social, and environmental responsibilities. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 6. Ensure availability and sustainable management of water and sanitation for all  

Goal 7. Ensure access to affordable, reliable, sustainable, and modern energy for all 

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

Goal 15. Protect, restore, and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss 

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development 

How the module will be assessed

Summative assessment will take the form of a written examination and a workshop piece of coursework.   

 

A two-hour closed book written exam will test your ability to demonstrate knowledge and understanding of the syllabus content, and your ability to apply the techniques and concepts covered to problems solving that are related to familiar and unseen examples.    

 

The summative workshop coursework will consist of 1 workshop. This will allow you to demonstrate your ability to use widely available scientific resources to locate relevant information and to critically review literature knowledge through the preparation of a short-written report. Marks will reflect the extent to which you have met the module learning outcomes, and you will be provided with detailed marking criteria. You will receive feedback on your work well before the written exam.   

 

Your learning will also be supported by two formative workshops, and feedback provided either orally or in written form after the face-to-face session. There will be a focus on supporting problem solving based on applying knowledge and understanding of heterogeneous catalysis.   

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:   

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.   

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session.   

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Written Assignment N/A
Exam - Spring Semester 80 Heterogeneous Catalysis 2

Syllabus content

The module will begin by covering the basic fundamental aspects and applications of heterogeneous catalysis, including the effects of catalysts on reaction rates and product distribution, requirements for practical catalysts, and the design of catalysts with attention to active phases, supports and promoters.   

Approaches to catalyst preparation will be covered, and several techniques used to characterise heterogeneous catalysts will be introduced. These will include temperature-programmed methods to monitor adsorption, oxidation, reduction, and desorption processes. Surface area and porosimetry by nitrogen physisorption and active metal surface area determination by chemisorption. The application of transmission and scanning electron microscopy to understand the structure of catalysts at the microscopic scale will be included.   

 

Principles and application of heterogeneous catalysts will be augmented by many examples. These will include catalysts for (i) water gas shift; (ii) refining processes; (iii) production and use of syngas, and catalytic routes to ammonia and methanol; (iv) atmospheric pollution control, with particular reference to the 3-way vehicle exhaust catalyst and selective catalytic reduction for stationary NOx emission control.   

 

The types of reactors used to apply heterogeneous catalysts will be introduced and the important features will be discussed. Two classes will be covered, (i) gas/solid reactors, and (ii) gas/liquid/solid reactors, the physical forms of the catalysts employed in the different reactors will be explained. The role of the catalytic reactor in an overall chemical process will be presented.   

 

Quantitative aspects of catalyst performance will be explained, covering gas hourly space velocity, conversion, product selectivity, rates of reaction and some kinetic parameters.   

 

Some examples of different catalysts will be covered by in-depth case studies for environmental protection applications. These will be the three-way catalytic converter for control of petrol vehicle emissions and controlling NOX emissions from stationary sources. Other different types of heterogeneous catalysts, like those that are applied to biorenewable and sustainable processes, will also be presented.  

 

Examples are zeolites, supported metals and metal oxides, these examples will present a number of different catalytic mechanisms, and will include Langmuir-Hinshelwood, Eley-Rideal and Mars-van Krevelen types, experimental methodologies to distinguish between these mechanisms will be investigated.  

 

The relationships between experimental catalyst activity data and catalyst structure will be discussed in the context of catalyst mechanism.   

 

Mechanisms of catalyst deactivation will be explored and illustrated with various examples.   

 

Essential Reading and Resource List: 

 

  • M. Bowker, The Basis and Applications of Heterogeneous Catalysis, Oxford Chemistry Primers, 1998, ISBN 0198559585   

  • Background Reading and Resource List    

  • J. M. Thomas, W. J. Thomas, Principles and Practice of Heterogeneous Catalysis, ISBN: 978-3-527-29239-4  


CH3315: Structure and Mechanism in Organic Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH3315
External Subject Code 100422
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Dr Niklaas Buurma
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module outlines: 

 

  • The techniques and approaches of physical organic chemistry that are be used to study mechanisms of organic, bioorganic, and catalytic reactions. 

  • MO theory as applied to the analysis of organic reactions, including in pericyclic reactions. 

On completion of the module a student should be able to

 

  • Propose a reasonable and falsifiable reaction mechanism for a reaction based on interpretation of physical and/or structural data. 

  • Propose experiments and predict outcomes of experiments designed to falsify proposed reaction mechanisms. 

  • Critically evaluate publications reporting studies of reaction mechanisms and orally report on the findings. 

  • Predict or rationalise the outcome of pericyclic processes, including periselectivity, regioselectivity and stereoselectivity based on analysis of molecular orbital interactions. 

How the module will be delivered

The module is taught using a combination of online recordings, interactive workshop-style lectures, a workshop, and a presentation session as detailed in the weekly module map.  

 

The online recordings present the required theory and students are required to watch the recordings before the corresponding interactive workshop-style lectures.  

 

The interactive lectures then apply the theory as presented in the recordings to exam-style problem-solving exercises.  

 

The workshop is used to explain what is required from the coursework and to allow students to form groups for their presentations.  

 

During the presentation session, students will deliver their summative assessed group presentation. 

     

Skills that will be practised and developed

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Graduate Attributes – Assessment:    

 

Group Presentation  

  • Contribute positively and effectively when working in a team, having an impact from the outset  

  • Communicate complex ideas effectively to diverse audiences  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgement in evaluating sources of information  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding  

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems  

 

Exam 

  • Communicate complex ideas effectively to diverse audiences  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgement in evaluating sources of information  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding  

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems 

  

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture 

Goal 12. Ensure sustainable consumption and production patterns  

How the module will be assessed

The module will be assessed through a group presentation and an exam. 

 

The summative assessed group presentation assesses your ability to critically evaluate publications reporting studies of reaction mechanisms and orally report on the findings, to work as a group to develop a presentation and to deliver an oral presentation on a mechanistic study. The marking criteria are the group’s ability in linking data to mechanism (a clear demonstration of how mechanism is supported by results from experiments is expected), in critical analysis (comments on quality of data and suggestions for future work are expected) and in quality of presentation (quality of slides, sequence of material & structure of presentation, coherence of presentation are assessed). The group is awarded a group mark from which individual marks are decided through peer marking, so that the average of the individual marks corresponds to the group mark.  

 

The exam assesses your ability to propose a reasonable and falsifiable reaction mechanism for a reaction based on interpretation of physical and/or structural data; propose experiments and predict outcomes of experiments designed to falsify proposed reaction mechanisms; predict or rationalise the outcome of pericyclic processes, including periselectivity, regioselectivity and stereoselectivity based on analysis of molecular orbital interactions. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

A resit exam and a resit presentation will be offered if required. The resit presentation is an individual presentation instead of a group presentation.  

Assessment Breakdown

Type % Title Duration(hrs)
Presentation 20 Group Presentation N/A
Exam - Spring Semester 80 Structure and Mechanism in Organic Chemistry 2

Syllabus content

 

Kinetics techniques in mechanistic studies: experimental methods for the acquisition of kinetic data; data analysis, curve fitting, statistics, and error analysis; simple rate laws; analysis of kinetic data in terms of reaction mechanisms; complex rate laws; numerical integration techniques 

            

Determination and interpretation of activation parameters in mechanistic studies: Gibbs energies and standard states; Δ‡Hø, Δ‡Sø and Δ‡V and their interpretation 

  

General & specific acid and base catalysis in mechanistic studies: pH rate profiles; equations and data analysis; mechanisms leading to general/specific acid/base catalysis 

  

Linear free energy relationships in mechanistic studies: Brønsted plots; Hammett plots 

 

Use of isotopes in mechanistic studies: isotopic labelling; cross-over experiments; primary kinetic isotope effects; solvent isotope effects 

 

Proposing reasonable reaction mechanisms: application of the techniques above to proposing reasonable reaction mechanisms 

 

MO theory as applied to non-pericyclic organic reactions: The application of MO theory to various organic reactions; stereoelectronic effects. 

  

MO theory as applied to pericyclic reactions: cycloadditions (including Diels-Alder and dipolar cycloadditions); symmetry-allowed and symmetry-forbidden reactions, regioselectivity, stereoselectivity; sigmatropic rearrangements; 1,n hydride shifts, Cope and Claisen rearrangements; electrocyclic reactions; photochemical processes; synthetic strategies involving pericyclic processes 

 


CH3316: Homogeneous Catalysis

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH3316
External Subject Code 100417
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Dr Paul Newman
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module will focus on aspects of homogeneous catalysis to include the derivation of catalytic cycles, identification of key reactions steps and highlight reactions of industrial relevance. Through carefully selected examples, you are able to appreciate the key concepts in catalytic cycles and how ligand design can play an important role in the development of new catalysts. 

 

Modern approaches to a more sustainable future are embedded in the module. 

On completion of the module a student should be able to

 

  • Construct catalytic cycles using fundamental organometallic reaction steps. 

  • Demonstrate how empirical data can be used to construct a catalytic cycle or identify key steps in the cycle. 

  • Explain chemo- regio- and stereo-selectivity and apply to catalytic mechanism. 

  • Demonstrate how knowledge of mechanism can lead to process optimisation. 

  • Explain the importance of the support ligand(s) and how they can be designed for function. 

  • Adapt/translate the knowledge gained to unseen catalytic processes. 

How the module will be delivered

 

The course consists of 22 x 1-hour face-to-face lectures during the Spring semester, with approximately 3 lectures a week for 7-8 weeks.  

 

Lectures may include some worked problems and informal formative questions to support principles introduced.  

 

These will help you to address the learning outcomes and provide opportunities to apply knowledge and develop understanding.  

 

The lecture schedule will follow the module map published prior to the start of the module. Lectures will be recorded and will be available following the live sessions.  

 

A combination of lecture slides and additional supporting notes will be available for you prior to the face-to-face lectures.  

 

Lecture material will be supported by two workshops. These are formative and will take the form of in person sessions focussing on supporting problem solving based on material from lectures.  

 

These formative workshops will provide you with guidance and support for the assessed coursework and examination A single summative coursework assessment will be released after the final lecture. 

Skills that will be practised and developed

Chemistry-Specific Skills: 

 

  • Interpretation of kinetic data to support catalytic mechanism.  

  • Appreciation of the importance of the support ligand(s) and their design. 

  • Designing experiments to prove/disprove turnover limiting steps. 

  • Use of spectroscopic data to support catalytic mechanism. 

  • Designing ligands for improved or novel catalytic performance. 

  • Problem solving. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

 Coursework 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

 

 Exam 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

Goal 6. Ensure availability and sustainable management of water and sanitation for all  

Goal 7. Ensure access to affordable, reliable, sustainable, and modern energy for all 

Goal 12. Ensure sustainable consumption and production patterns  

Goal 13. Take urgent action to combat climate change and its impacts  

Goal 14. Conserve and sustainably use the oceans, seas, and marine resources for sustainable development 

How the module will be assessed

Summative assessment will take the form of a two-hour written examination and a piece of coursework. 

 

The exam will require a demonstration of key concepts developed during the course especially the ability to apply techniques and concepts to unseen problems related to the material covered.  

 

The summative coursework will allow you to demonstrate your ability to demonstrate an understanding of key concepts and apply them to unseen or partially seen material. This will be a mixture of multiple choice and open questions. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  

 

You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Coursework N/A
Exam - Spring Semester 80 Homogeneous Catalysis 2

Syllabus content

Reactions of metal-alkene, metal-CO, and metal-alkyl complexes relevant to homogeneous catalysis and a discussion of mechanisms (hydrogenation, transfer hydrogenation, hydrogen-borrowing, Wilkinson’s substrate scope, Crabtree’s catalyst), carbonylation (hydroformylation, Monsanto, Eastman), metathesis, asymmetric catalysis). Use of kinetic and/or spectroscopic data for the deduction of catalytic cycles and/or key catalytic steps.  

 

Sustainability and catalyst design. Hard and soft Lewis acid catalysis. Co-operative catalysis. Hydroamination.  


CH3317: Engineering Biosynthesis

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH3317
External Subject Code 100948
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Dr James Redman
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module concerns the engineering of biosynthetic pathways for synthesis of organic chemicals for use as pharmaceuticals, agrochemicals, flavours/fragrances, and fuels.  

 

Biosynthesis enables sustainable manufacture of complex molecules in multistep routes using fermentation from renewable feedstocks under benign conditions.  

 

The combination of synthetic chemistry with biosynthesis provides an efficient avenue to novel compounds for screening as drugs.  

 

The strategies and challenges for production of organic chemicals through biosynthetic pathways will be described and illustrated with examples drawn from the biosynthesis of different classes of secondary metabolite. 

On completion of the module a student should be able to

  • Propose intermediates and reaction pathways for the biosynthesis of a given metabolite.  

  • Choose strategies to engineer enzymes and metabolic pathways to produce a compound of a given structure. 

  • Retrieve, interpret and communicate data, findings and procedures relating to biosynthesis from journals and databases. 

How the module will be delivered

The module will be delivered primarily using lectures (22 hours across one semester) where the principles of biosynthesis of different classes of secondary metabolite will be introduced including case studies of engineering from the literature.  

 

In addition, lectures will include worked problems and informal ad hoc formative activities.  

 

Workshops (two formative, one summative) will be used to enhance and assess problem-solving and literature searching skills. 

Skills that will be practised and developed

You will practice applying the concepts of synthetic organic chemistry to enzyme catalysed biosynthetic pathways. You will develop skills in proposing appropriate starting materials and enzymes to synthesise a given target structure. 

  

Chemistry specific skills: 

 

  • Assignment of metabolites to a particular pathway, and proposal of biosynthetic intermediates and transformations;   

  • Apply strategies for modifying a biosynthetic pathway to increase yields or produce novel products;  

  • Predicting the outcome of biosynthetic processing of an unnatural substrate;   

  • Choosing appropriate synthetic substrates for biosynthetic pathways to generate novel compounds.  

  

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:  

   

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

 Coursework 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate, and present with impact. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

 

 Exam 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate, and present with impact. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 3. Ensure healthy lives and promote well-being for all at all ages

Goal 12. Ensure sustainable consumption and production patterns

Goal 13. Take urgent action to combat climate change and its impacts

Goal 15. Protect, restore, and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss 

 

How the module will be assessed

Formative assessment: The first two workshops will be assessed formatively, and feedback provided either orally or in written form. This will give you an opportunity to revise the factual module content and to practice applying it to deduce and propose biosynthetic pathways. 

 

Summative assessment: An examination will test knowledge of biosynthetic pathways, metabolic engineering strategies and their application to previously unseen molecules. A summatively assessed workshop in the form of a written report will allow you to demonstrate your ability to use electronic resources to locate relevant information in the literature to provide the context for a proposal for production of a novel molecule using an engineered biosynthetic pathway. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Written Assignment N/A
Exam - Spring Semester 80 Engineering Biosynthesis 2

Syllabus content

Rationale for engineering pathways in primary and secondary metabolism for sustainable production of complex organic chemicals. 

 

Biosynthetic pathways for common classes of secondary metabolite, with examples drawn from polyketides, terpenoids, alkaloids and non-ribosomal peptides. 

 

Strategies for modifying enzyme selectivity and activity – rational design, screening, directed evolution approaches.  

 

Case studies of engineering metabolite biosynthesis. 

 

Reconstituting metabolic pathways in new hosts (choice of host - considerations such as precursor availability, toxicity of intermediates, compartmentalisation, PTMs of pathway enzymes, accessory proteins).  

 

Efficiently creating molecular diversity by combining synthetic chemistry, biosynthesis and high throughput techniques. 

 


CH3325: Project

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH3325
External Subject Code 100417
Number of Credits 30
Level L6
Language of Delivery English
Module Leader Dr Athanasia Dervisi
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module consists of a supervised research project. This may be in any area of practical or theoretical chemistry, including educational and literature review projects. 

Supervisors are allocated following student preference as far as possible. 

Students prepare a written report and video presentation based on their results. These are marked by two examiners.  

On completion of the module a student should be able to

Describe and present the objectives, methods, and outcomes of a project in oral and written form.  

• Retrieve and communicate data, findings, and procedures from a variety of sources.  

• Analyse a topic to give a discussion and critical assessment of the significant issues.  

• Devise and execute a complex plan of work towards a goal.  

• Analyse and interpret findings and use these to predict behaviour with which to inform future work.  

How the module will be delivered

Independent research investigation, supervised by a member of academic staff or their nominee from research group. 

132 (44 × 3 hour) timetabled hours of supervised or independent investigation. 

 

Skills that will be practised and developed

Intellectual skills: 

 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgement in evaluating sources of information  

  • Analysis of an advanced topic, discussion, and critical assessment of the significant issues;  

 

Chemistry-Specific Skills: 

 

  • Searching and selecting from the literature, discussing it critically in the context of the project undertaken;  

  • Independently conducting an extended investigation based on a chemistry topic;   

  • Recording of all working notes in an appropriate manner with reference to risk and hazard information where applicable;  

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes: 

 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Graduate Attributes – Assessment:    

  

Practical Assessment          20% 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Presentation                        30%  

  • Communicate complex ideas effectively to diverse audiences.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Dissertation                         50%  

  • Communicate complex ideas effectively to diverse audiences.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

Goal 4. Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, decent work for all

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation

Goal 12. Ensure sustainable consumption and production patterns 

Goal 13. Take urgent action to combat climate change and its impacts

Goal 14. Conserve and sustainably use the oceans, seas, and marine resources for sustainable development 

Goal 15. Protect, restore, and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development 

How the module will be assessed

The module will be assessed and on the basis of engagement/performance during the project and via coursework, including a written report and a video presentation of the project. 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  

You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.  

 

All resit assessments will be held in the first available Examination period after the Examining Board.  

 

Reassessment will consist of a further attempt at report and/or oral presentation, depending on those parts that contributed to failure on original submission.

It will not normally be possible to extend or repeat experimental work as part of reassessment.  

Assessment Breakdown

Type % Title Duration(hrs)
Dissertation 50 Written Report N/A
Presentation 30 Video Presentation N/A
Practical-Based Assessment 20 Intellectual and/or Practical Contribution N/A

Syllabus content

This module consists of a supervised research project. 

This may be in any area of practical or theoretical chemistry, including educational and literature review projects. 

Supervisors are allocated following student preference as far as possible. 

Students prepare a written report and video presentation based on their results. These are marked by two examiners.    


CH3375: Prosiect

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH3375
External Subject Code 100417
Number of Credits 30
Level L6
Language of Delivery Welsh
Module Leader Dr Heulyn Jones
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

Mae’r modiwl hon yn cynnwys prosiect ymchwil wedi’i oruchwylio. Gall hyn fod mewn unryw faes o gemeg, ac mae’n cynnwys prosiectau addysgiadol a phrosiectau am adolygiadau pwnc. Bydd goruchwylwyr yn cael eu dyrannu yn ôl dewisiadau’r myfyrwyr lle’n bosib. Bydd myfyrwyr yn paratoi adroddiad ysgrifennedig a chyflwyniad fideo wedi’i selio ar eu canlyniadau. Bydd rhain yn cael eu marcio gan ddau arholwr. Bydd y goruchwylio, adroddiadau a’r arholi yn cael eu gwneud yn y Gymraeg.

On completion of the module a student should be able to

  1. Cynllunio a chwblhau ymchwiliad nofel mewn pwnc o unryw ran o gemeg ymarferol neu ddamcaniaethol; 
  2. Dewis ffynhonnell o’r llenyddiaeth gwyddonol a’i roi mewn cyd-destun y prosiect, gan gynnwys asesiad critigol o’r gwaith blaenorol; 
  3. Nodi’r canlyniadau mewn modd addas, gan gyfeirio tugat at risg a pherygl lle’n briodol; 
  4. Cyflwyno’r canlyniadau yn ysgrifenedig ac ar lafar; 
  5. Cynllunio a chreu adroddiad manwl mewn ffurf addas ar bob agwedd o’r prosiect. 

How the module will be delivered

132 (44 × 3 awr) o oriau wedi’u hamserlenni i ymchwiliad annibynnol dan oruchwyliad. 

Skills that will be practised and developed

Sgiliau deallusol

  • Dadansoddi pwnc dwys, trafod ac asesu’r rhwysterau pwysig; 
  • Cynllunio a chwblhau gweithgaredd cymhleth; 

Sgiliau cemegol  

  • Chwilio a dewis o’r llenyddiaeth gwyddonol, ei drafod yn gritigol yng nghyswllt y prosiect; 
  • Cwblhau ymchwiliad estynedig ar y pwnc cemegol; 
  • Nodi’r canlyniadau mewn modd addas, gan gyfeirio tugat at risg a pherygl lle’n briodol; 

Sgiliau trosglwyddadwy  

  • Dadansoddi corff sylweddol o wybodaeth;  
  • Trefnu a pharatoi adroddiadau; 
  • Cyflwyno adroddiad ysgrifenedig ac ar lafar. 

How the module will be assessed

Bydd y modiwl yn gael ei asesu ar sail cyflwyniad fideo, adroddiad ysgrifenedig a pherfformiad/ymgysylltiad drwy gydol y prosiect. 

 

Cyfleoedd ar gyfer ail-asesiad: 

Bydd myfyrwyr sydd â chaniatâd gan y Bwrdd Arholi ar gyfer ail-asesiad yn y modiwl yn cael eu gofyn i gyflwyno adroddiad ysgrifenedig a chyflwyniad ar lafar wedi’u addasu yn ystod yr un flwyddyn academaidd. Bydd hwn ond yn digwydd mewn achosion lle mae asesiad gan y goruchwylydd yn dderbyniol, ond lle mae amgylchiadau esugusodol wedi effeithio ar pharatoad yr adroddiad gwreiddiol. 

Assessment Breakdown

Type % Title Duration(hrs)
Dissertation 50 Adroddiad ysgrifenedig N/A
Presentation 30 Cyflwyniad Fideo N/A
Practical-Based Assessment 20 Cyfraniad deallusol ac ymarferol N/A

Syllabus content

Mae’r modiwl yma’n cynnwys prosiect ymchwil wedi’i oruchwylio. Gall hwn fod mewn unryw faes o gemeg, boed yn ymarferol, ddamcaniaethol, yn cynnwys prosiectau yn ymwneud â addysg a phrosiectau sy’n adolygu’r llenyddiaeth. Bydd goruchwylwyr yn cael eu penodi ar sail dewis y myfyriwr, lle’n bosib. Bydd myfyrwyr yn paratoi adroddiad ysgrifenedig a chyflwyniad fideo ar ganlyiadau’r prosiect. Bydd rhain yn cael eu mario gan ddau arholwr.   


CH4302: Advanced Organometallic and Coordination Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH4302
External Subject Code 101389
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Dr Angelo Amoroso
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module will build upon concepts introduced at level 5 and develop them to address more advanced bonding schemes for metal-ligand and metal-metal interactions. 

Furthermore, qualitative, and quantitative spectroscopic and magnetic properties of octahedral, tetrahedral, and lower symmetry co-ordination complexes will be discussed, thus allowing a detailed analysis of the electronic state of the metal centre. 

The final part of the module deals specifically with organotransition metal chemistry, covering structure and bonding, reaction mechanisms, and catalysis.  

On completion of the module a student should be able to

 

  • Describe the nature of orbital interactions in metal-ligand and metal-metal examples  

  • Apply spectroscopic and magnetic methods to probe the nature and properties of metal containing complexes.  

  • Demonstrate an awareness of the potential applications of metal complexes.  

  • Interpret physical data and justify observations by predicting structure and/or by using models of orbital overlap  

  • Recognise bonding/structure relationships in transition metal-mediated reactions.   

  • Be aware of the underlying physical processes affecting spectroscopic observations.   

How the module will be delivered

A blend of face-to-face lecture material delivery with on-line learning activities, learning support and feedback.

Content will be delivered primarily using lectures (22-hours) across one semester, equating to two lectures per week). In addition, lectures will include worked problems and informal ad hoc formative tests. 

This will address the learning outcomes under the ‘Knowing’ heading, while examples presented will show students how they may also demonstrate their achievement of the ‘Acting’ learning outcomes. 

Workshops (2 x 2-hour, one formative, one summative) will be used to enhance and assess problem-solving skills related to the retrieval and analysis of data. 

Tutorials (2 x 1 hour, formative) will allow tutors to monitor and guide the progress of students in meeting all learning outcomes.  

Skills that will be practised and developed

 

Chemistry-specific skills: 

 

  • Developing your abilities to analyse the nature of the bonding with a transition metal complex.  

  • By assigning oxidation state and metal centre geometry, an appropriate MO diagram may be produced. 

  • You will develop an understanding of ligand nature and their interaction with the metal centre. Effects on the reactivity of the complex (redox or chemical bond formation) will be discussed.  

  • Metal-metal orbital interactions may be discussed, allowing the further development of the students understanding of multiple bonding.   

  • You will develop the necessary skills to identify the appropriate physical techniques to analyse and assess the bonding (and magnetic) interactions in transition metal complexes.  

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

Written Assessment 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Actively reflect on own studies achievements and self-identity 

 

Exam 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Actively reflect on own studies achievements and self-identity 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 6. Ensure availability and sustainable management of water and sanitation for all 

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, and decent work for all  

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

Goal 15. Protect, restore, and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss 

How the module will be assessed

Formative assessment: The first workshop will be assessed formatively, and feedback provided either orally or in written form. This will prepare you in tackling problem-solving exercises in the examination.  

 

Summative assessment: The second workshop will be assessed summatively, and feedback provided either orally or in written form. 

A written exam (2 h) will test your ability to demonstrate your knowledge and understanding of the syllabus content, and your ability to apply the techniques/concepts covered to unseen problems. 

 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  

 

You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Written Assignment N/A
Exam - Autumn Semester 80 Advanced Organometallic and Coordination Chemistry 2

Syllabus content

 

The syllabus will draw from a range of topics, chosen to exemplify orbital interactions and resulting physical and chemical properties. These topics will allow the development of the your ability to utilise spectroscopic methods to investigate the nature of the materials. These topics may include:  

 

Structure and bonding in organometallic chemistry: 

 

Description of bonding models for π-acceptor and π-donor ligands, including CO, alkenes (Dewar Chatt Duncanson model), NO+, RO- and NR2-, Physical evidence and consequences of bonding, applications of infrared spectroscopy.  

Other σ-bonding ligands, e.g. H-, and alkyl ligands.  

Metal carbonyl complexes, preparation, properties, and structure.  

Bonding and structure in metal alkene complexes including conjugated anionic and polyalkene ligands and influences upon reactivity.  

Metal carbon multiply bonded systems, carbene (Fischer type) and alkylidene/alkylidyne (Schrock type) compounds. Examination of bonding models for these systems and relationships with experimentally observed reactivity.  

Transition metal hydrides and dihydrogen complexes.  

Spectroscopic techniques of study of organometallic compounds (e.g. NMR etc.).  

Mechanistic organometallic chemistry  

Classic reaction pathways of organometallic compounds, introduction to catalytic cycles  

Oxidative additions, reductive eliminations, migratory insertions, hydrogen migrations.  

Reactions of metal-alkene, metal-CO, and metal-alkyl complexes relevant to homogeneous catalysis and a discussion of mechanisms (e.g. polymerisation, metathesis, cross-coupling, asymmetric catalysis).  

 

UV-vis Spectroscopy  

Assigning transitions and calculating Δ and Racah B for d1-d9 HS and d6 LS.  

Line width and signal intensity in d-d transition. 

 

Magnetochemistry  

Orbital contributions:  

Nature of A and E term complexes and TIP;  

Nature of T terms: Kotani plots and their derivation.  

Magnetic properties of lower symmetry complexes:TBP, trigonal and trigonal prismatic.  

Organometallic examples.  

Elucidation of geometry utilising magnetic data.  

Effect of paramagnetism on NMR; contact shift; shift reagents; Evans’ method.  

Non-dilute systems.  

Multimetallic systems.  

Exchange mechanisms: for design or for rationalising systems.  

Exchange integral: measuring for d9 systems.  

Complexes with co-ordinated radicals:  

Innocent and non-innocent ligands.  

Examples considering magnetic, electrochemical and EPR properties.  


CH4303: Advanced Synthetic Strategies

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH4303
External Subject Code 100422
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Dr Mark Elliott
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module builds on previous organic chemistry modules (CH5103, CH5203) to show how the reactions covered can be applied to the synthesis of complex synthetic targets. 

A number of modern synthetic transformations are introduced at this level. 

The concept of retrosynthetic analysis is formally introduced, to show how the synthesis of a target molecule can be rationally designed. 

In order to accomplish this, a selection of previously covered reactions will be presented again with a focus on their strategic application. 

On completion of the module a student should be able to

  • Have a broad understanding of synthetic chemistry transformations, as evidenced by an ability to identify nucleophilic and electrophilic sites and to recognise plausible bond-forming steps. 

  • Identify sensible approaches to target molecules of significance and moderate complexity. 

  • Appreciate the relevance of modern synthetic approaches (including transition metal catalysis, stereoselectivity, protecting groups) to complex target synthesis.  

  • Perform a retrosynthetic analysis and forward synthesis for a given target molecule, and to describe the approach using appropriate terminology. 

How the module will be delivered

Learning activities will be a blend of traditional lectures (22 hours) containing problem-solving formative components. Answers to given problems will be covered during lectures and/or provided videos/supplementary resources.

Three workshops will be delivered, with a focus on developing problem-solving skills. The first two of these will be formative, with feedback provided. The final one will be summatively assessed.

Tutorials (2 x 1 hour) will also be delivered to allow further opportunities for informal student feedback to be provided. 

Skills that will be practised and developed

Intellectual Skills: 

 

  • Solve problems within the context of synthetic chemistry to provide solutions that meet set criteria. 

 

Chemistry-Specific Skills: 

 

  • Students will have the opportunity to practice the retrosynthetic analysis of synthetic targets of biological/medicinal importance. This will include an increased appreciation for the stereochemical outcome of organic transformations. 

  • Devise the most applicable strategy for the preparation of complex targets, and to identify approaches that will not be effective. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

 Coursework               20% 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity 

 

 Exam                         80% 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity 

 

 Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture 

Goal 3. Ensure healthy lives and promote well-being for all at all ages  

Goal 12. Ensure sustainable consumption and production patterns

How the module will be assessed

Formative assessment will take place throughout the lecture sessions, with staff facilitating peer discussion. In this way, students will be able to monitor their own progress. Formative workshops will build on this, with feedback given to prepare students for summative assessment. 

A summative workshop will assess the student’s understanding of fundamental chemical reactivity as applied to relevant synthetic targets.

A written exam (2 hour) will test the student’s knowledge and understanding as elaborated under the learning outcomes.  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Workshop N/A
Exam - Autumn Semester 80 Advanced Synthetic Strategies 2

Syllabus content

Consolidation of Previous Material 

Critical review of previously covered material, with a focus on synthetic applicability. 

 

Retrosynthetic analysis 

Introduction to disconnections and the logic of synthesis  

C-X disconnections – alcohols, halides, ethers, sulfides and amines and 1,2- & 1,3-difunctionalised compounds 

C-C disconnections and synthesis using carbonyl group, including alkene synthesis, enolate alkylation selectivity 

Synthesis of 1,3-, 1,4- and 1,5-dicarbonyl compounds 

Use of protecting groups when chemoselectivity issues arise 

Manipulation of double bonds, ring opening, ring expansion and ring formation techniques 

 

Pericyclic reactions 

Electrocyclic reactions, Cycloadditions, Sigmatropic rearrangements (Diels-Alder reaction, 1,3-dipolar cycloaddition, Claisen rearrangement etc.) 

 

Palladium-catalysed coupling methods 

Disconnection for the synthesis of polyunsaturated systems  

Selected applications in synthesis, with emphasis on the retrosynthetic features and stereoselective synthesis 

Precursor synthesis where appropriate 

 

Metathesis 

Definition of the various types of ring closuring (ene-ene, ene-yne and yne-yne) and cross metathesis; identifying applications in total synthesis 

 


CH4304: Quantum and Statistical Mechanics of Molecules and Solids

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH4304
External Subject Code 101050
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Professor James Platts
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

The module describes fundamental concepts in quantum and statistical mechanical description of molecules and solids.  

 

Starting from solution of the Schrödinger equation for model systems, quantum mechanical methods for approximate description of molecular electronic structure, and their applications, will be discussed.  

 

Statistical mechanics will be based around the definition of partition functions and will employ such definitions in discussion of thermodynamics and kinetics.  

 

Extension of quantum mechanics to the solid state will lay the basis for band theory description of the electronic structure of metals, semi-conductors, and insulators. 

On completion of the module a student should be able to

 

  • Demonstrate awareness of methods for description of electronic structure of molecules and solids. 

  • Describe means to relate molecular to macroscopic properties using the techniques of statistical mechanics. 

  • Evaluate results of electronic structure calculations, critically assess their performance and extract chemically relevant properties. 

  • Calculate thermodynamic and kinetic properties of molecular systems from knowledge of molecular properties. 

  • Identify and predict key properties of materials based on a band structure description of their electronic structure. 

  • Retrieve and communicate data, findings, and procedures from a variety of sources (literature, electronic databases, experiments/calculations). 

 

How the module will be delivered

Content will be delivered primarily using lectures (22 hours across one semester, equating to approximately two lectures per week).  

 

In addition, lectures will include worked problems and informal ad hoc formative tests.  

  

Workshops will be used to enhance and assess problem-solving skills related to the retrieval and analysis of data. 

 

Tutorials will allow tutors to monitor and guide your progress in meeting all learning outcomes. 

 

 

Skills that will be practised and developed

Chemistry-specific skills: 

  

  • Applying ideas from fundamental physical chemistry to understand how modern descriptions of the electronic structure of molecules and solids are constructed and applied to reach a unified picture of molecular properties.  

  • You will develop a detailed understanding of how properties of molecules and materials are related to their electronic structure, and how these properties are related to observed macroscopic behaviour. 

  • The module will also involve a large element of problem solving using both numerical and algebraic techniques, based around real examples of theoretical methods. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:  

   

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

 Written Assessment 

  • Communicate complex ideas effectively to diverse audiences. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

 

 Exam 

  • Communicate complex ideas effectively to diverse audiences. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

 

   

Sustainable Development Goals:      

   

This module does not align with any of the Sustainable Development Goals, but its topics do underpin all. 

How the module will be assessed

A written exam (2 hours) will test your ability to demonstrate your knowledge and understanding of the syllabus content, and your ability to apply the techniques/concepts covered to unseen problems.  

 

A single piece of coursework will allow you to demonstrate knowledge of key concepts and apply that knowledge to chemical problems.  

 

Marks will reflect the extent to which you have met the module learning outcomes shown above. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  

 

You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Coursework N/A
Exam - Autumn Semester 80 Quantum and Statistical Mechanics of Molecules and Solids 2

Syllabus content

Quantum mechanics: Schrödinger equation, Born-Oppenheimer approximation; Exact solutions for model problems; electron spin and the Pauli principle; Coulomb and exchange energies; Variation theorem, approximate wavefunctions and energies; LCAO approximation, Slater determinants and basis sets; Hartree-Fock and self-consistent field approach; Electron correlation: Post-HF and density functional theory methods; potential energy surfaces and chemical properties. 

  

Statistical mechanics: Review of basic concepts, probability, kinetic theory of gases, microstates, Boltzmann distribution; Definition of partition functions for translational, rotational, and vibrational degrees of freedom Thermodynamics from partition functions: internal energy, entropy, and heat capacity; role of partition functions in rate constants derived from transition state theory. 

  

Band theory: Band structure and its relationship to the electronic structure of solids; Band structure at interfaces; Periodic quantum chemistry approach for theoretical analysis of solid-state structure; Bloch functions for wavefunctions for periodic systems; Reciprocal space and use of sampling to determine approximate band structures. 


CH4305: Macromolecules of Life

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH4305
External Subject Code 100948
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Dr James Redman
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module concerns the structure, chemistry and analysis of proteins and nucleic acids. 

The module illustrates how fundamentals of chemical structure and reaction mechanisms can be applied to the physical and functional properties of proteins and nucleic acids. 

Real-life applications in medicine and industry will be outlined. Students will learn about the range of analytical and structure determination techniques that can be applied to biological macromolecules. 

The principles of modern methods for DNA synthesis, amplification and sequencing will be elucidated. Principles of enzyme catalysis and kinetics will be discussed, together with an overview of the roles played by cofactors. 

The processes of transcription and translation will be described with an overview of how molecular biology enables production of new proteins.  

 

On completion of the module a student should be able to

  • Explain the roles of macromolecules in the chemistry of life. 

  • Predict and explain the function and reactivity of biological macromolecules in terms of chemical structure and reaction mechanism. 

  • Select experimental strategies to synthesise and analyse biological macromolecules. 

How the module will be delivered

Content will be delivered primarily using lectures (22 hours across one semester, equating to two lectures per week). Lectures will include worked problems representative of exam questions.

Tutorials (2 x 1 hour, formative) will give the opportunity to practice solving problems and interpretating experimental observations. 

Skills that will be practised and developed

Chemistry-Specific Skills: 

 

  • Applying ideas from functional group chemistry and mechanistic organic chemistry to understand how the structure of proteins and nucleic acids permit them to perform their biological function.  

  • Student will learn how to select appropriate techniques for synthesis and analysis of biological macromolecules. 

  • Students will also gain familiarity with computer-based methods for searching, retrieving, and visualising protein and nucleic acid sequences and structures from on-line databases. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:  

   

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

 Coursework                 20% 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

 

 Exam                           80% 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:  

 

Goal 3. Ensure healthy lives and promote well-being for all at all ages

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation

Goal 12. Ensure sustainable consumption and production patterns 

How the module will be assessed

Formative assessment: Lectures will include the opportunity to attempt problems based on exam questions with immediate feedback provided in oral form. Students will be provided with problems to attempt in advance of the tutorials. Feedback will be provided orally during the tutorial. This will prepare students to tackle problem-solving exercises in the examination and professional practice.

Summative assessment: A written exam (2-hours) will test students’ ability to demonstrate their knowledge of the syllabus content, and their ability to apply the concepts covered to unseen problems. The coursework (on-line workshop) will allow students to demonstrate the ability to use electronic resources to locate and visualise relevant information in biological chemistry. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Workshop N/A
Exam - Autumn Semester 80 Macromolecules of Life 2

Syllabus content

Overview of protein structure; Ramachandran plots and secondary structure; Tertiary and quaternary structure; Protein structure prediction; Introductory NMR and mass spectrometric characterization of proteins.

Principles of protein function; Binding and catalysis. Myoglobin and hemoglobin; Physical basis of enzyme catalysis including the role of cofactors, Michaelis-Menten kinetics; Mechanisms of enzyme inhibition; Simple examples of enzyme-catalysed transformations.

Structure, biophysical properties and chemistry of nucleotides (DNA and RNA); DNA synthesis, amplification, and sequencing; DNA-based technologies and their applications.

Transcription and translation; mRNA and tRNA synthesis; The genetic code and the molecular basis of ribosomal protein synthesis. 


CH4309: Placement Experience

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH4309
External Subject Code 100417
Number of Credits 80
Level L6
Language of Delivery English
Module Leader Dr Athanasia Dervisi
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module is taken by MChem students on placement abroad or in industry. The main feature will be a substantial project on a topic determined by the placement provider. Placements will be approved by the School placement coordinator. This will be carried out on a timescale appropriate for the particular placement, with duration no less than 9 months and up to 12 months. The main report will be supplemented by a short placement review, describing the particular environment of the placement. 

On completion of the module a student should be able to

• Describe and present the objectives, methods and outcomes of a project in oral and written form. 

• Retrieve and communicate data, findings and procedures from a variety of sources. 

• Analyse a topic to give a discussion and critical assessment of the significant issues. 

• Devise and execute a complex plan of work towards a goal. 

• Analyse and interpret findings and use these to predict behaviour with which to inform future work. 

• Adapt to professional working practices in an industrial or overseas setting. 

• Contribute positively and effectively when working in a team. 

How the module will be delivered

Students take this module whilst undertaking a placement abroad or in industry.  It consists primarily of project work supervised by the placement provider.  The results are presented in a written report, and also in a seminar at Cardiff University.

Skills that will be practised and developed

Intellectual skills 

  1. Identify, define and analyse complex issues and ideas, exercising critical judgement in evaluating sources of information 

  2. Analysis of an advanced topic, discussion and critical assessment of the significant issues; 

  3. Planning, and executing a complex activity; 

Chemistry-specific skills 

  1. Searching and selecting from the literature, discussing it critically in the context of the project undertaken; 

  2. Conducting an extended project at a chemical sciences-using placement provider; 

  3. Recording of all working notes in an appropriate manner with reference to risk and hazard information where applicable; 

Transferable skills 

  1. Communicate complex ideas effectively to diverse audiences;  

  2. Organisation and presentation of oral and written reports; 

  3. Adapt to working in an unfamiliar culture; 

  4. Learn from others in a work-based environment 

 

How the module will be assessed

The module will be assessed via coursework including a written report, a video presentation of the project, and an essay reviewing the placement. 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

All resit assessments will be held in the first available Examination period after the Examining Board. 

Students who are permitted by the Examining Board to be reassessed in this module, will need to resubmit each failed component of the module (report, video presentation and/or placement review) during the next available Examination Period. 

Assessment Breakdown

Type % Title Duration(hrs)
Report 65 Placement Experience Report N/A
Presentation 25 Placement Experience Video Presentation N/A
Written Assessment 10 Placement Experience Placement Review N/A

Syllabus content

The placement experience will be undertaken in the industrial or university host approved by the placement scheme coordinator. The main feature will be a substantial project on a chemical sciences topic determined by the host. This will be carried out on a time scale appropriate for the particular placement, but is expected to take about 800 hours of student time, including all literature work, project work, preparation of presentation and written report. For academic placements, it is expected that all of the nominal 800 hours will be spent on the project at the host. For the industrial placements, the aim is for a similar arrangement, but it is recognised that the nature of the host’s work may require this to be modified and directed work related to the host’s business may take up some of the time, though a substantial independent and original project must be included. 

The main report will be supplemented by a short placement review, describing the particular environment of the placement - aspects of cultural differences in teaching and learning methods in host university, skills development during the placement, business aspects of the company for industrial placements. 

Regular contact will be maintained throughout, primarily through the personal tutor, with involvement by the placement coordinator as necessary. 


CH4311: Advanced Organometallic and Coordination Chemistry for Distance Learners

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH4311
External Subject Code 101389
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Dr Angelo Amoroso
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

 

This module will build upon concepts introduced at level 5 and develop them to address more advanced bonding schemes for metal-ligand and metal-metal interactions.  

 

Furthermore, qualitative, and quantitative spectroscopic and magnetic properties of octahedral, tetrahedral, and lower symmetry co-ordination complexes will be discussed, thus allowing a detailed analysis of the electronic state of the metal centre.  

 

The final part of the module deals specifically with organotransition metal chemistry, covering structure and bonding, reaction mechanisms, and catalysis.  

 

 

On completion of the module a student should be able to

  • Describe the nature of orbital interactions in metal-ligand and metal-metal examples  

  • Apply spectroscopic and magnetic methods to probe the nature and properties of metal containing complexes.  

  • Demonstrate an awareness of the potential applications of metal complexes.   

  • Predict the physical properties resultant from the orbital overlap in varying complexes   

  • Interpret physical data and justify observations by predicting structure and/or by using models of orbital overlap  

  • Recognise bonding/structure relationships in transition metal-mediated reactions.  

   

  

How the module will be delivered

You will study this module remotely, whilst undertaking a placement abroad or in industry. You will be provided with learning resources, including electronic versions of lectures delivered in Cardiff, and required to complete regular assignments. 

 

Content will be delivered using recorded lectures (22 hours across one semester, equating to two lectures per week). In addition, recorded lectures will include worked problems and informal ad hoc formative tests.  

 

This will address the learning outcomes under the ‘Knowing’ heading, while examples presented will show you how you may also demonstrate your achievement of the ‘Acting’ learning outcomes. 

  

Workshops (formative and summative) will be used to enhance and assess problem-solving skills related to proposed mechanisms, data retrieval and analysis. Submission of workshops and return of marks and feedback will be performed on-line. 

 

Skills that will be practised and developed

Chemistry-Specific Skills:  

 

  • Developing your abilities to analyse the nature of the bonding with a transition metal complex.  

  • By assigning oxidation state and metal centre geometry, an appropriate MO diagram may be produced. 

  • You will develop an understanding of ligand nature and their interaction with the metal centre. Effects on the reactivity of the complex (redox or chemical bond formation) will be discussed.  

  • Metal-metal orbital interactions may be discussed, allowing the further development of the students understanding of multiple bonding.   

  • You will develop the necessary skills to identify the appropriate physical techniques to analyse and assess the bonding (and magnetic) interactions in transition metal complexes.  

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

Coursework 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Class test 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Reassessment:             

 

Coursework              40% 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Class test                60% 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 6. Ensure availability and sustainable management of water and sanitation for all  

How the module will be assessed

You will undertake a series of online assignments throughout the year, which will allow you to demonstrate your ability to judge and critically review relevant information. 

 

Formative assessment: an online workshop will be made available and assessed formatively, during the beginning of the module. Online feedback will be provided after the workshop’s submission deadline. This will prepare the student in tackling problem-solving exercises.  

Summative assessment: There are three online workshops that will be assessed summatively, and online feedback will be provided after each workshop’s submission deadline. 

The workshops will test the student’s ability to demonstrate their knowledge and understanding of the syllabus content, and their ability to apply the techniques/concepts covered to unseen problems. 

 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

Students who are permitted by the Examining Board to be reassessed in this module during the same academic session will sit an examination (2h) during the Resit Examination Period.  

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 40 Workshop N/A
Class Test 60 Open-book Class Test N/A

Syllabus content

The syllabus will draw from a range of topics, chosen to exemplify orbital interactions and resulting physical and chemical properties. These topics will allow the development of the student’s ability to utilise spectroscopic methods to investigate the nature of the materials. These topics may include:  

 

Structure and bonding in organometallic chemistry  

Description of bonding models for π-acceptor and π-donor ligands, including CO, alkenes (Dewar Chatt Duncanson model), NO+, RO-and NR2-; Physical evidence and consequences of bonding, applications of infrared spectroscopy.  

Other σ-bonding ligands, e.g. H-, and alkyl ligands.  

Metal carbonyl complexes, preparation, properties, and structure.  

Bonding and structure in metal alkene complexes including conjugated anionic and polyalkene ligands and influences upon reactivity.  

Metal carbon multiply bonded systems, carbene (Fischer type) and alkylidene/alkylidyne (Schrock type) compounds. Examination of bonding models for these systems and relationships with experimentally observed reactivity.  

Transition metal hydrides and dihydrogen complexes.  

Spectroscopic techniques of study of organometallic compounds (e.g. NMR etc.).  

Mechanistic organometallic chemistry  

Classic reaction pathways of organometallic compounds, introduction to catalytic cycles  

Oxidative additions, reductive eliminations, migratory insertions, hydrogen migrations.  

Reactions of metal-alkene, metal-CO, and metal-alkyl complexes relevant to homogeneous catalysis and a discussion of mechanisms (e.g. polymerisation, metathesis, cross-coupling, asymmetric catalysis).  

 

UV-vis Spectroscopy  

Assigning transitions and calculating Δ and Racah B for d1-d9 HS and d6 LS.  

Line width and signal intensity in d-d transition. 

 

Magnetochemistry  

Orbital contributions:  

Nature of A and E term complexes and TIP;  

Nature of T terms: Kotani plots and their derivation.  

Magnetic properties of lower symmetry complexes:TBP, trigonal and trigonal prismatic.  

Organometallic examples.  

Elucidation of geometry utilising magnetic data.  

Effect of paramagnetism on NMR; contact shift; shift reagents; Evans’ method.  

Non-dilute systems.  

Multimetallic systems.  

Exchange mechanisms: for design or for rationalising systems.  

Exchange integral: measuring for d9 systems.  

Complexes with co-ordinated radicals:  

Innocent and non-innocent ligands.  

Examples considering magnetic, electrochemical and EPR properties.  

 


CH4313: Quantum and Statistical Mechanics of Molecules and Solids for Distance Learners

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH4313
External Subject Code 101050
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Professor James Platts
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

The module describes fundamental concepts in quantum and statistical mechanical description of molecules and solids.  

 

Starting from solution of the Schrödinger equation for model systems, quantum mechanical methods for approximate description of molecular electronic structure, and their applications, will be discussed. 

 

Statistical mechanics will be based around the definition of partition functions and will employ such definitions in discussion of thermodynamics and kinetics.  

 

Extension of quantum mechanics to the solid state will lay the basis for band theory description of the electronic structure of metals, semi-conductors, and insulators. 

On completion of the module a student should be able to

 

  • Demonstrate awareness of methods for description of electronic structure of molecules and solids. 

  • Describe means to relate molecular to macroscopic properties using the techniques of statistical mechanics. 

  • Evaluate results of electronic structure calculations, critically assess their performance and extract chemically relevant properties. 

  • Calculate thermodynamic and kinetic properties of molecular systems from knowledge of molecular properties. 

  • Identify and predict key properties of materials based on a band structure description of their electronic structure. 

  • Retrieve and communicate data, findings, and procedures from a variety of sources (literature, electronic databases, experiments/calculations). 

 

 

How the module will be delivered

Content will be delivered primarily using lectures (22 hours across one semester, equating to approximately two lectures per week).  

 

In addition, lectures will include worked problems and informal ad hoc formative tests.  

  

Workshops will be used to enhance and assess problem-solving skills related to the retrieval and analysis of data. 

Skills that will be practised and developed

Chemistry-specific skills: 

  

  • These will be focused on applying ideas from fundamental physical chemistry to understand how modern descriptions of the electronic structure of molecules and solids are constructed and applied to reach a unified picture of molecular properties.  

  • You will develop a detailed understanding of how properties of molecules and materials are related to their electronic structure, and how these properties are related to observed macroscopic behaviour.  

  • The module will also involve a large element of problem solving using both numerical and algebraic techniques, based around real examples of theoretical methods. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

 Written Assessment  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

Class test 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  

Sustainable Development Goals:      

   

This module does not align with any of the Sustainable Development Goals, but its topics do underpin all. 

   

How the module will be assessed

 

Assessment of this module is solely through coursework, allowing you to demonstrate knowledge of key concepts and apply knowledge to chemical problems. Marks will reflect the extent to which you have met the module learning outcomes shown above. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 40 Workshop N/A
Written Assessment 60 Open-book Class Test N/A

Syllabus content

Quantum mechanics: Schrödinger equation, Born-Oppenheimer approximation; Exact solutions for model problems; electron spin and the Pauli principle; Coulomb and exchange energies; Variation theorem, approximate wavefunctions and energies; LCAO approximation, Slater determinants and basis sets; Hartree-Fock and self-consistent field approach; Electron correlation: Post-HF and density functional theory methods; potential energy surfaces and chemical properties. 

  

Statistical mechanics: Review of basic concepts, probability, kinetic theory of gases, microstates, Boltzmann distribution; Definition of partition functions for translational, rotational, and vibrational degrees of freedom Thermodynamics from partition functions: internal energy, entropy, and heat capacity; role of partition functions in rate constants derived from transition state theory. 

  

Band theory: Band structure and its relationship to the electronic structure of solids; Band structure at interfaces; Periodic quantum chemistry approach for theoretical analysis of solid-state structure; Bloch functions for wavefunctions for periodic systems; Reciprocal space and use of sampling to determine approximate band structures. 


CH4314: Macromolecules of Life for Distance Learners

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH4314
External Subject Code 100948
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Dr James Redman
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module concerns the structure, chemistry and analysis of proteins and nucleic acids. The module illustrates how fundamentals of chemical structure and reaction mechanisms can be applied to the physical and functional properties of proteins and nucleic acids. Real-life applications in medicine and industry will be outlined. Students will learn about the range of analytical and structure determination techniques that can be applied to biological macromolecules. The principles of modern methods for DNA synthesis, amplification and sequencing will be elucidated. Principles of enzyme catalysis and kinetics will be discussed, together with an overview of the roles played by cofactors. The processes of transcription and translation will be described with an overview of how molecular biology enables production of new proteins. 

On completion of the module a student should be able to

• Explain the roles of macromolecules in the chemistry of life. 

• Predict and explain the function and reactivity of biological macromolecules in terms of chemical structure and reaction mechanism. 

• Select experimental strategies to synthesise and analyse biological macromolecules. 

 

How the module will be delivered

Content will be delivered using recorded lectures (22 h across two semesters, equating to approximately one lecture per week). Lectures will include worked problems representative of exam questions. 

 

Skills that will be practised and developed

Chemistry-specific skills will be focused on applying ideas from functional group chemistry and mechanistic organic chemistry to understand how the structure of proteins and nucleic acids permit them to perform their biological function. Students will learn how to select appropriate techniques for synthesis and analysis of biological macromolecules. Students will also gain familiarity with computer-based methods for searching, retrieving and visualising protein and nucleic acid sequences and structures from on-line databases. 

How the module will be assessed

Formative assessment: Example problems based on examination questions will be covered during lectures. Students will have access to tutorial problems and an answer guide with which to check their solutions. Students may attempt an on-line workshop as a formative exercise and will receive feedback.

Summative assessment: There will be a summative workshop in autumn semester that will cover topics from the first half of the lectures, and a spring semester workshop covering topics from the second half. These will be open-book non-timed exercises and will require students to search for data on-line, visualise it and solve problems. 

  A timed (2 h) open-book exercise at the end of spring semester will test students’ ability to apply the knowledge and concepts from the syllabus to unseen problems. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

Students who are permitted by the Examining Board to be reassessed in this module during the same academic session will complete an additional piece of coursework during the Resit Examination Period. 

 

 

 

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 40 Coursework N/A
Written Assessment 60 Coursework N/A

Syllabus content

Overview of protein structure; Ramachandran plots and secondary structure; Tertiary and quaternary structure; Protein structure prediction; Introductory NMR and mass spectrometric characterization of proteins. 

Principles of protein function; Binding and catalysis. Myoglobin and hemoglobin; Physical basis of enzyme catalysis including the role of cofactors, Michaelis-Menten kinetics; Mechanisms of enzyme inhibition; Simple examples of enzyme-catalyzed transformations. 

Structure, biophysical properties and chemistry of nucleotides (DNA and RNA); DNA synthesis, amplification and sequencing; DNA-based technologies and their applications. 

Transcription and translation; mRNA and tRNA synthesis; The genetic code and the molecular basis of ribosomal protein synthesis. 


CH5301: Advanced Practical Training for Medicinal Chemists

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5301
External Subject Code 100420
Number of Credits 20
Level L6
Language of Delivery English
Module Leader Dr Michaela Serpi
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

 

This module will expand upon the practical skills in medicinal chemistry introduced in the second year. Key C-C and C-X bond forming reactions (for example Wittig, SNAr, generation and reaction of organolithium compounds, trifluoromethylation) will be introduced along with further Pd-catalysed couplings that are essential in medicinal chemistry. Key skills to safely and reliably handle air sensitive reagents and reactions will be developed, alongside a deeper understanding of the kinetic and thermodynamic control of reaction products. Additional seminars will cover relevant topics, such as good manufacturing practice and medical imaging. Exposure to liquid chromatography, automated purification systems and computational chemistry software will prepare the participants for their future careers in the field.   

On completion of the module a student should be able to

 

  • Safely and effectively synthesise compounds using air and moisture sensitive reagents and catalysts.  

 

  • Predict and explain reaction outcomes with reference to reaction mechanism, kinetic and thermodynamic factors.  

 

  • Present experimental work in a concise and consistent manner and critically assess both synthetic and biological results. 

 

How the module will be delivered

 

This module will be delivered through blended learning. Online resources will supplement hands-on learning in the teaching laboratory:  

 

  • Online laboratory manuals will allow participants to plan experimental work beforehand in a safe and timely manner and also introduce key medicinal chemistry concepts   

 

  • Participants will carry out ten synthetic  experiments with an additional two computational experiments being delivered live online   

 

  • The write-ups for the experimental work will be split into four reports. Prior to each submission, a 1 h session will be held to clearly explain the expectations for the reports 

Skills that will be practised and developed

  • Carrying out COSHH assessments to ensure safe practice prior to experimental work  

 

  • Essential practical synthetic chemistry skills   

 

  • Safely manipulating air sensitive reagents and reactions  

 

  • Operating automated purification and liquid chromatography systems   

 

  • Identifying and assessing the purity of reaction products using modern analytical and spectroscopic methods  

 

  • Preparing concise and accurate scientific reports of experimental data  

 

  • Calculating the lipophilicity and pKa values of molecules in-silico  

 

  • Predicting reaction outcomes from mechanism and pathways  

 

  • The use of several software packages used in the field of medicinal chemistry  

 

  • Time management.  

 

Employability skills:     

This module is delivered and aligns with the following University Graduate Attributes:   

 

  1. Contribute positively and effectively when working in a team, having an impact from the outset. 

  1. Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities. 

  1. Be respectful of the roles of others and acknowledge the limits of their own skills/experience. 

  1. Listen to and take account of the views of others. 

  1. Communicate complex ideas effectively to diverse audiences. 

  1. Contribute to discussions, negotiate and present with impact. 

  1. Deliver, accept and act on constructive feedback.  

  1. Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  1. Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  1. Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  1. Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  1. Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  1. Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future. 

 

Sustainable Development Goals:       

    

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

  • Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture  

  • Goal 3. Ensure healthy lives and promote well-being for all at all ages 

How the module will be assessed

 

There are 2 points of assessment in this module:   

 

Practical skills (60%)   

 

Feedback on practical work and COSH assessments will be delivered by experienced laboratory demonstrators. Quality of each participant’s reaction product samples will be assessed by appearance, 1H NMR spectroscopic and LC/MS analysis. Consistent attendance of practical sessions is essential.    

 

  Experimental write-up (40%)   

 

The remaining assessment will compromise of four experimental write-ups, which will include additional questions to broaden understanding of related area. The write-ups will be assessed with regards to: concise scientific writing style, analysis of spectroscopic and LC-MS data, ability to problem solve using a combination of medicinal chemistry concepts and appropriate software.   

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

 

If you do not pass the ‘Practical Work’ component of this module, you will be required to resit as an internal student during the next academic session. 

 

 

Assessment Breakdown

Type % Title Duration(hrs)
Practical Skills Assessment 60 Experimental Work (14 experiments) N/A
Written Assessment 40 Coursework - Experimental write-up (4 reports) N/A

Syllabus content

Principles and operation of state-of-the-art laboratory equipment for reactions and purification.  

 

Experimental techniques for safely carrying out a range of reactions involving air and moisture sensitive reagents and/or catalysts. Typical reactions could include Wittig, SNAr, generation and reaction of organolithium compounds, trifluoromethylation, Pd catalysed couplings.  

 

Applications of all the aforementioned reactions in drug discovery and development.  

 

Classes of Pd cross-coupling reactions and their application in synthesis.  

 

Optimising reactions through investigation and consequent understanding of mechanism, kinetics and thermodynamics.  

 

Presentation of experimental work in a concise and consistent manner.  

 

Critical assessment of data and conclusions from synthetic and biological experiments.  

 

Computational determination of the lipophilicity and ionisation state of molecules. 

 


CH5306: New Modalities in Drug Discovery

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5306
External Subject Code 100420
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Dr James Redman
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module will explore trends and developments in drug discovery that are attempting to move beyond rule-of-five small molecule drugs that target protein binding pockets. The limitations of traditional small molecule approaches to drugs and their targets will be described, and the rationale for pursuing novel structural classes, modes of action and previously undruggable targets will be discussed with reference to recent examples. Opportunities for efficient strategies for design and screening of compounds will be explored, and the challenges associated with pharmacokinetics, formulation and manufacture highlighted.   

On completion of the module a student should be able to

  • Exemplify current research towards drugs that do not conform to the typical structures and modes of action of action of small molecules and biologics.  

  • Relate the structures of new modality drugs to their molecular mechanism of action.  

  • Compare the synthesis, screening, formulation and manufacture of new modality drugs to conventional small molecules and biologics.  

How the module will be delivered

A blend of lectures with face-to-face small group learning support and feedback. 

The module is delivered as 18 one-hour lectures in combination with four one-hour workshops. 

Skills that will be practised and developed

Subject-specific skills:  

Identifying molecular characteristics of potential drug targets that make development of conventional small molecule drugs challenging.  

Recognising and proposing molecular interactions that can be employed to direct drugs against challenging targets.  

Identifying the structures of the main classes of non-small molecule drug currently under development and predicting how these engage with their target to generate a biological response.  

Proposing synthesis and screening strategies for compounds with new modalities, predicting where challenges might arise with pharmacokinetics, formulation and manufacturing and propose solutions to these problems.  

Transferable skills:  

Searching, retrieving, synthesising, and evaluating the literature.  

Presenting information in writing.  

 

Employability skills:     

This module is delivered and aligns with the following University Graduate Attributes:   

 

  1. Contribute positively and effectively when working in a team, having an impact from the outset. 

  1. Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities. 

  1. Be respectful of the roles of others and acknowledge the limits of their own skills/experience. 

  1. Listen to and take account of the views of others. 

  1. Communicate complex ideas effectively to diverse audiences. 

  1. Contribute to discussions, negotiate and present with impact. 

  1. Deliver, accept and act on constructive feedback.  

  1. Understand organisations, their stakeholders and their impact on the community. 

  1. Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  1. Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  1. Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  1. Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  1. Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  1. Understanding organisations, their stakeholders and their impact on the economy 

  1. Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Sustainable Development Goals:       

    

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

  • Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture  

  • Goal 3. Ensure healthy lives and promote well-being for all at all ages 

How the module will be assessed

Formative assessment: Problem solving exercises will be conducted in small groups. This will prepare you to tackle problem-solving exercises in the examination.  

Summative assessment: The coursework will allow you to demonstrate your ability to identify, interpret and propose research through the preparation of a written account. A written exam (2 h) will test your ability to demonstrate your knowledge and understanding of the syllabus content, and your ability to apply the techniques/concepts covered to unseen problems.  

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Written Coursework N/A
Exam - Autumn Semester 80 New Modalities in Drug Discovery 2

Syllabus content

Molecular characteristics of conventional small molecule and biological drugs and their targets. Limitations of small molecules and biologicals. Drugability of targets.  

 

Peptides and peptidomimetics, for example cyclic peptides, stabilised hairpins, helices and foldamers.  

 

Targeting proteins for degradation – PROTACs  

 

Oligonucleotides and their analogues. Chemical structures, target and modes of action (antisense, siRNA, gene editing). Delivery challenges. 

 

Conjugates – oligonucleotide/peptide/carbohydrate/small molecule conjugates.  

 

Illustrations will be selected from drugs that have recently been approved or are under development, and emerging concepts under research in academic and industrial laboratories. 


CH5312: Advanced Synthetic Strategies for Distance Learners

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5312
External Subject Code 100417
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Professor Thomas Wirth
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module builds on previous organic chemistry modules (CH5103, CH5203) to show how the reactions covered can be applied to the synthesis of complex synthetic targets. 

A number of modern synthetic transformations are introduced at this level. 

The concept of retrosynthetic analysis is formally introduced, to show how the synthesis of a target molecule can be rationally designed. In order to accomplish this, a selection of previously-covered reactions will be presented again with a focus on their strategic application. 

 

On completion of the module a student should be able to

Have a broad understanding of synthetic chemistry transformations, as evidenced by an ability to identify nucleophilic and electrophilic sites and to recognise plausible bond-forming steps. 

Identify sensible approaches to target molecules of significance and moderate complexity. 

Appreciate the relevance of modern synthetic approaches (including transition metal catalysis, stereoselectivity, protecting groups) to complex target synthesis. 

Perform a retrosynthetic analysis and forward synthesis for a given target molecule, and to describe the approach using appropriate terminology. 

 

How the module will be delivered

Recorded lectures (22 h) will be delivered to students via Panopto. These will contain problem-solving formative components which students will be able to access. Answers to given problems will be provided in lecture recordings and/or provided videos/supplementary resources. 

Three workshops will be delivered, with a focus on developing problem-solving skills. The first of these will be formative, with feedback provided. The final two will be summatively assessed. 

Skills that will be practised and developed

Students will have the opportunity to practice the retrosynthetic analysis of synthetic targets of biological/medicinal importance. This will include an increased appreciation for the stereochemical outcome of organic transformations. 

 

How the module will be assessed

Formative assessment will take place by provision of suitable problems during lecture videos, and provision of answers/associated discussion in the same/subsequent lecture videos. In this way, students will be able to monitor their own progress. A formative workshop will build on this, with feedback given to prepare students for summative assessment. 

Two summative workshops will assess the student’s understanding of fundamental chemical reactivity as applied to relevant synthetic targets. 

An online assessment (2 h) will test the student’s ability to demonstrate their knowledge and understanding of the syllabus content, and their ability to apply the techniques/concepts covered to unseen problems. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

Students who are permitted by the Examining Board to be reassessed in this module during the same academic session will sit a synoptic online assessment (2h) during the Resit Examination Period. 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 40 Coursework N/A
Written Assessment 60 Coursework N/A

Syllabus content

Retrosynthetic analysis 

Introduction to disconnections and the logic of synthesis 

C-X disconnections – alcohols, halides, ethers, sulfides and amines and 1,2- & 1,3-difunctionalised compounds 

C-C disconnections and synthesis using carbonyl group, including alkene synthesis, enolate alkylation selectivity 

Synthesis of 1,3-, 1,4- and 1,5-dicarbonyl compounds 

Use of protecting groups when chemoselectivity issues arise 

Manipulation of double bonds, ring opening, ring expansion and ring formation techniques 

Pericyclic reactions 

Electrocyclic reactions, Cycloadditions, Sigmatropic rearrangements (Diels-Alder reaction, 1,3-dipolar cycloaddition, Claisen rearrangement etc.) 

Palladium-catalysed coupling methods 

Disconnection for the synthesis of polyunsaturated systems 

Selected applications in synthesis, with emphasis on the retrosynthetic features and stereoselective synthesis 

Precursor synthesis where appropriate 

Metathesis 

Definition and emphasis on catalyst types for both ring closure (ene-ene, ene-yne and yne-yne) and cross metathesis; experimental methods; brief mention of utility in polymer synthesis and total synthesis 

 

 


CH5325: Project

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5325
External Subject Code 100420
Number of Credits 40
Level L6
Language of Delivery English
Module Leader Dr Louis Luk
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module consists of a supervised project in an area of medicinal chemistry. This may be practical chemistry, computational chemistry, a literature review, or combination of these. Supervisors are allocated following student preference as far as possible. Training will be provided in any specialised techniques that are required during the project. You will prepare a written report and video presentation. 

 

On completion of the module a student should be able to

 

  • Plan and safely carry out an original project in an area of medicinal chemistry; 

  • Create and manage records of methods, observations and data; 

  • Source and critically analyse literature to place the project in the context of preceding work; 

  • Present the project context, methods and outcomes in oral and written form according to professional standards. 

How the module will be delivered

 

According to the needs of individual projects, hands-on training will be provided in any essential laboratory or computational techniques. You will receive training in documenting and reporting their project work. The project will consist of 132 (44 × 3 hours) timetabled hours of supervised independent investigation. 

 

Skills that will be practised and developed

Intellectual skills:  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgement in evaluating sources of information   

  • Analysis of an advanced topic, discussion, and critical assessment of the significant issues;   

Chemistry-Specific Skills:  

  • Searching and selecting from the literature, discussing it critically in the context of the project undertaken;   

  • Independently conducting an extended investigation based on a chemistry topic;    

  • Recording of all working notes in an appropriate manner with reference to risk and hazard information where applicable;   

Employability skills:     

   

  • This module is delivered and aligns with the following University Graduate Attributes:  

  • Contribute positively and effectively when working in a team, having an impact from the outset.   

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.   

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.   

  • Listen to and take account of the views of others.   

  • Communicate complex ideas effectively to diverse audiences.   

  • Contribute to discussions, negotiate, and present with impact.   

  • Consider own personal and professional ethical, social, and environmental responsibilities.   

  • Demonstrate personal and professional integrity, reliability, and competence.   

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals   

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.   

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding.  

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.   

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.   

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.   

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.   

  • Understanding organisations, their stakeholders, and their impact on the economy   

  • Actively reflect on own studies achievements and self-identity   

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.   

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.   

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.   

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning.  

   

Graduate Attributes – Assessment:     

   

Practical Assessment  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.   

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

Presentation   

  • Communicate complex ideas effectively to diverse audiences.   

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.   

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

Dissertation 

  • Communicate complex ideas effectively to diverse audiences.   

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.   

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

 

Sustainable Development Goals:      

   

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

  

Goal 4. Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all 

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, decent work for all 

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

Goal 12. Ensure sustainable consumption and production patterns  

Goal 13. Take urgent action to combat climate change and its impacts 

Goal 14. Conserve and sustainably use the oceans, seas, and marine resources for sustainable development   

Goal 15. Protect, restore, and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss  

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development 

How the module will be assessed

 

The module will be assessed on the basis of a video presentation, a written report, and engagement/performance during the project. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Students who are permitted by the Examining Board to be reassessed in this module during the same academic session will be asked to submit a revised written report and video presentation prior to the start of the next session if the assessment by the supervisor is satisfactory. If the assessment by the supervisor is unsatisfactory, students will be required to repeat the module during the next academic session. 

Assessment Breakdown

Type % Title Duration(hrs)
Dissertation 50 Written Report N/A
Presentation 30 Video Presentation N/A
Practical-Based Assessment 20 Intellectual and/or practical contribution N/A

Syllabus content

This module consists of an original supervised project in an area of medicinal chemistry. The supervisor will be allocated according to student preferences where possible. The project may involve amongst other things, synthetic chemistry, biological testing, computational modelling, data processing, literature review and analysis or a combination of these areas. Hands-on training will be provided in specialised laboratory, computational or data analysis techniques according to the requirements of individual projects. 

 

 


CH5330: Foundations of Statistics and Data Science

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5330
External Subject Code 100406
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Dr Andrea Folli
Semester Autumn Semester
Academic Year 2025/6

Assessment Breakdown

Type % Title Duration(hrs)
Class Test 15 Probability and Distributions N/A
Class Test 15 Regression, Variance and Correlation N/A
Class Test 15 Decision Theory and Categorical Analysis N/A
Written Assessment 55 Group Project N/A

CH5350: Advanced Chemistry Practical

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5350
External Subject Code 100417
Number of Credits 30
Level L6
Language of Delivery English
Module Leader Professor Kenneth Harris
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This is a module of practical work, designed to familiarise learners with advanced research techniques used for experiments of a synthetic and/or instrumental nature, and with professional applications of information technology. 

 

The module will also include exercises designed to develop critical analysis, problem-solving, oral, and written communication, and to enhance your employability. 

On completion of the module a student should be able to

  • Obtain and act upon safety and hazard information for chemicals, apparatus and procedures; 

  • Use appropriate equipment and information technology in an effective way; 

  • Critically assess experimental and computational results in relation to chemical principles, relating data to molecular structure and properties; 

  • Write a concise report on all results obtained; 

  • Critically review primary literature chemistry articles.  

How the module will be delivered

Approximatively 60 hours (20 x 3 hours) laboratory classes, plus approximatively 6 hours of seminars / workshops. 

 

You will undertake several tasks in the synthetic, instrumental and computer laboratory. For each one, performance in the laboratory and understanding of underlying concepts will be tested by one or more written reports, submission of samples/data/code, or online tests.  

Skills that will be practised and developed

Intellectual skills: 

 

  • You will be able to draw conclusions about reaction mechanisms by combining experimental and spectroscopic data, developing analytical and critical thinking skills 

  • You will be developing the ability to relate the experimental data to the underlying theory enhancing your critical thinking skills  

  • You will analyse problems and identify the critical decisions needed in designing approaches to solutions, developing problem solving skills 

  • You will develop skills in applying computers for processing data, simulation and automating tasks. 

 

Chemistry-specific skills: 

 

You will develop skills in: 

 

  • Preparing, isolating, and purifying organic and inorganic compounds using standard procedures; 

  • Manipulating air-sensitive compounds under an inert atmosphere; 

  • Preparing and isolating aqueous coordination compounds; 

  • Obtaining and interpreting IR and UV/vis spectra of organic and transition-metal compounds; 

  • Interpreting IR and NMR spectra of organic compounds and hence critically assess the outcome of a reaction; 

  • Investigating kinetics and reaction mechanism by interpreting experimental data and computational tools;  

  • Using experimental data to calculate an unknown value; 

  • Assessing the risks associated with the use of chemicals and apparatus for themselves, the others, and the environment, which will help developing awareness of health and safety along with ethical, social, and environmental responsibilities; 

  • Recording methods and data in an organised manner and presenting a written report and oral discussion clearly and concisely, developing the ability to effectively communicate results; 

  • Determining the most appropriate format for presentation of experimental data acquiring impactful presentation skills; 

  • Showing scientific judgement and ability to select appropriate experimental or computational methods to tackle a problem developing problem solving, analytical and independent critical thinking skills; 

  • Reviewing primary literature chemistry articles, developing the ability to exercise critical judgement in evaluating literature sources 

 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:  

   

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.   

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Graduate Attributes – Assessment:    

  

Written Assessment                10% 

 

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback. 

  • Consider own personal and professional ethical, social, and environmental responsibilities. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

Practical Assessment              90% 

 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Listen to and take account of the views of others. 

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback. 

  • Consider own personal and professional ethical, social, and environmental responsibilities. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path. 

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development 

How the module will be assessed

 

Formative assessment: an online test, consisting of numerical and multiple-choice answers, will be assessed formatively and will help you to ensure that you are performing and interpreting calculations correctly for the applications of information technology part of the module. 

Summative assessment: The learning outcomes will be assessed continuously on the basis of written reports, samples of compounds prepared, code, spectroscopic and analytical data, performance in the laboratory. Consistent attendance of practical sessions is essential.  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.  

 

Practical work cannot be repeated after the scheduled time for the module is over. Reassessment involves completing the written assessments based on the student’s own data.  

 

Students who need to repeat or do the laboratory work will be required to resit as an internal student in the next academic session.  

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 10 Key Skills Exercise N/A
Practical-Based Assessment 90 Lab work and Reports N/A

Syllabus content

Synthetic chemistry will include the preparation of a range of compounds on small and medium scale. Reactions will involve organic, organometallic and coordination compounds, manipulation of air-sensitive compounds, and characterisation and analysis using NMR, IR, UV, and other techniques as appropriate. 

 

Physical chemistry will involve accurate measurement of physical properties and recording, interpreting, and using experimental data to calculate an unknown value.  

 

Application of information technology in chemistry – application of theoretical methods and calculations to probe molecular structure, bonding, and reactivity. Use of information technology, including coding, for calculations and automation. 

 

Key Skills - critical analysis of the primary chemical literature 


CH6303: Strategies in Organic and Biological Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH6303
External Subject Code 100422
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Dr Mark Elliott
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module integrates advanced concepts from organic chemistry and biological chemistry, building on previous modules to explore the synthesis of complex organic molecules and the chemistry of biological macromolecules. 

 

The module focuses on modern synthetic transformations and retrosynthetic analysis, alongside the synthesis and analysis of nucleic acids and peptides. 

 

Students will gain an understanding of how organic chemistry principles apply to biological systems, with real-life applications in medicine and industry. 

On completion of the module a student should be able to

  • Demonstrate a comprehensive understanding of synthetic chemistry transformations, identifying nucleophilic and electrophilic sites, and recognising plausible bond-forming steps. 

  • Perform retrosynthetic analysis and plan a forward synthesis for target molecules of moderate complexity, describing the approach with correct terminology 

  • Explain the synthesis and analysis of nucleic acids and peptides, applying organic chemistry principles to biological macromolecules. 

How the module will be delivered

Learning activities will be a blend of lectures (22 hours) containing problem-solving formative components. Answers to given problems will be covered during lectures and/or provided videos/supplementary resources. 

Three workshops will be delivered, with a focus on developing problem-solving skills. The first two of these will be formative, with feedback provided. The final one will be summatively assessed. 

Tutorials (2 x 1 hour) will also be delivered to allow further opportunities for informal student feedback to be provided. 

Skills that will be practised and developed

 

Intellectual Skills: 

 

  • Solve problems within the context of synthetic chemistry to provide solutions that meet set criteria. 

 

Chemistry-Specific Skills: 

  • Practice retrosynthetic analysis of synthetic targets, including those of biological and medicinal importance. 

  • Devise strategies for the preparation of complex organic and biological targets, identifying effective and ineffective approaches. 

  • Apply organic chemistry principles to the synthesis and analysis of nucleic acids and peptides. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

 Coursework 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity 

 

 Exam 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity 

 

 Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture 

Goal 3. Ensure healthy lives and promote well-being for all at all ages  

Goal 12. Ensure sustainable consumption and production patterns  

How the module will be assessed

Formative assessment will take place throughout the lecture sessions, with staff facilitating peer discussion. In this way, you will be able to monitor your own progress. Formative workshops will build on this, with feedback given to prepare you for summative assessment.  

A summative workshop will assess your understanding of fundamental chemical reactivity as applied to relevant synthetic targets. 

A written exam (2 hour) will test your knowledge and understanding as elaborated under the learning outcomes.  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Workshop N/A
Exam - Autumn Semester 80 Strategies in Organic and Biological Chemistry 2

Syllabus content

Application of organic reactions: Construction of complex molecules using multi-step synthetic pathways. 

 

Retrosynthetic Analysis: Introduction to disconnections and the logic of synthesis, including C-X and C-C disconnections. 

 

Synthesis of Dicarbonyl Compounds: Techniques for synthesising 1,3-, 1,4-, and 1,5-dicarbonyl compounds. 

 

Use of Protecting Groups: Strategies for addressing chemoselectivity issues. 

 

Pericyclic Reactions: Exploration of electrocyclic reactions, cycloadditions, and sigmatropic rearrangements. 

 

Metathesis: Definition and application of ring-closing and cross metathesis in total synthesis. 

 

Protein and nucleic acid chemistry: Principles of nucleic acid and peptide synthesis, separation and analysis. Use of mass spectrometry and HPLC for the characterisation of peptides. 

 


CH6313: Strategies in Organic and Biological Chemistry for Distance Learners

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH6313
External Subject Code 100417
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Dr Mark Elliott
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module integrates advanced concepts from organic chemistry and biological chemistry, building on previous modules to explore the synthesis of complex organic molecules and the chemistry of biological macromolecules. 

 

The module focuses on modern synthetic transformations and retrosynthetic analysis, alongside the synthesis and analysis of nucleic acids and peptides. 

 

Students will gain an understanding of how organic chemistry principles apply to biological systems, with real-life applications in medicine and industry. 

On completion of the module a student should be able to

 

  • Demonstrate a comprehensive understanding of synthetic chemistry transformations, identifying nucleophilic and electrophilic sites, and recognising plausible bond-forming steps. 

  • Perform retrosynthetic analysis and plan a forward synthesis for target molecules of moderate complexity, describing the approach with correct terminology 

  • Explain the synthesis and analysis of nucleic acids and peptides, applying organic chemistry principles to biological macromolecules. 

 

How the module will be delivered

 

Recorded lectures (22 hours) will be delivered to students on-line.  

These will contain problem-solving formative components which students will be able to access. 

Answers to given problems will be provided in lecture recordings and/or provided videos/supplementary resources.  

Three workshops will be delivered, with a focus on developing problem-solving skills. The first of these will be formative, with feedback provided.  

The final two will be summatively assessed.  

Skills that will be practised and developed

 

Intellectual Skills: 

 

  • Solve problems within the context of synthetic chemistry to provide solutions that meet set criteria. 

 

Chemistry-Specific Skills: 

  • Practice retrosynthetic analysis of synthetic targets, including those of biological and medicinal importance. 

  • Devise strategies for the preparation of complex organic and biological targets, identifying effective and ineffective approaches. 

  • Apply organic chemistry principles to the synthesis and analysis of nucleic acids and peptides. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

 Coursework 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity 

 

 Exam 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity 

 

 Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture 

Goal 3. Ensure healthy lives and promote well-being for all at all ages  

Goal 12. Ensure sustainable consumption and production patterns  

 

How the module will be assessed

 

Formative assessment will take place by provision of suitable problems during lecture videos, and provision of answers/associated discussion in the same/subsequent lecture videos. In this way, you will be able to monitor your own progress. A formative workshop will build on this, with feedback given to prepare you for summative assessment.  

Two summative workshops will assess your understanding of fundamental chemical reactivity as applied to relevant synthetic targets.  

An online assessment (2 hour) will test your ability to demonstrate your knowledge and understanding of the syllabus content, and your ability to apply the techniques/concepts covered to unseen problems.  

  

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.  

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 40 Workshop N/A
Written Assessment 60 Open-book Class Test N/A

Syllabus content

Application of organic reactions: Construction of complex molecules using multi-step synthetic pathways. 

 

Retrosynthetic Analysis: Introduction to disconnections and the logic of synthesis, including C-X and C-C disconnections. 

 

Synthesis of Dicarbonyl Compounds: Techniques for synthesising 1,3-, 1,4-, and 1,5-dicarbonyl compounds. 

 

Use of Protecting Groups: Strategies for addressing chemoselectivity issues. 

 

Pericyclic Reactions: Exploration of electrocyclic reactions, cycloadditions, and sigmatropic rearrangements. 

 

Metathesis: Definition and application of ring-closing and cross metathesis in total synthesis. 

 

Protein and nucleic acid chemistry: Principles of nucleic acid and peptide synthesis, separation and analysis. Use of mass spectrometry and HPLC for the characterisation of peptides. 


CH6325: Project

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH6325
External Subject Code 100417
Number of Credits 40
Level L6
Language of Delivery English
Module Leader Professor Damien Murphy
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

Outline Description of Module 

 

This module consists of a supervised research project spread over two semesters. This may be in any area of practical or theoretical chemistry, including educational and literature review projects.  

 

Supervisors are allocated following student preference as far as possible.  

 

Students prepare a synopsis of the research area they are working, and a written report and video presentation based on their results.  

On completion of the module a student should be able to

 

Describe and present the objectives, methods, and outcomes of a project in oral and written form.  

Retrieve and communicate data, findings, and procedures from a variety of sources.  

Analyse a topic to give a discussion and critical assessment of the significant issues.  

Devise and execute a complex plan of work towards a goal.  

Research the literature to further research aims and design experimental protocols. 

Analyse and interpret findings and use these to predict behaviour with which to inform future work. 

 

How the module will be delivered

 

Independent research investigation, supervised by a member of academic staff or their nominee from a research group. 

Skills that will be practised and developed

Intellectual skills: 

 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgement in evaluating sources of information  

  • Analysis of an advanced topic, discussion, and critical assessment of the significant issues;  

 

Chemistry-Specific Skills: 

 

  • Plan and carry out an original investigation in a chemistry topic; 

  • Searching and selecting from the literature, discussing it critically in the context of the project undertaken;  

  • Independently conducting an extended investigation based on a chemistry topic;   

  • Recording of all working notes in an appropriate manner with reference to risk and hazard information where applicable; 

  • Plan and compose a detailed report in standard format on all aspects of the project.  

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes: 

 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Graduate Attributes – Assessment:    

  

Project Synopsis 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Practical Assessment 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Presentation  

  • Communicate complex ideas effectively to diverse audiences.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Dissertation  

  • Communicate complex ideas effectively to diverse audiences.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:  

 

Goal 4. Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all 

 

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, decent work for all 

 

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

 

Goal 12. Ensure sustainable consumption and production patterns  

 

Goal 13. Take urgent action to combat climate change and its impacts 

 

Goal 14. Conserve and sustainably use the oceans, seas, and marine resources for sustainable development  

 

Goal 15. Protect, restore, and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss 

 

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development 

How the module will be assessed

 

The module will be assessed and on the basis of engagement/performance during the project and via coursework, including a written report and a video presentation of the project.  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.   

 

You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.  

 

All resit assessments will be held in the first available Examination period after the Examining Board.  

 

Reassessment will consist of a further attempt at report and/or oral presentation, depending on those parts that contributed to failure on original submission. 

 

It will not normally be possible to extend or repeat experimental work as part of reassessment.  

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Project Synopsis N/A
Practical Skills Assessment 20 Intellectual and/or Practical Contribution N/A
Presentation 20 Video Presentation N/A
Dissertation 40 Written Report N/A

Syllabus content

 

This module consists of a supervised research project.  

 

This may be in any area of practical or theoretical chemistry, including educational and literature review projects.  

 

Supervisors are allocated following student preference as far as possible.  

 

You will prepare a project synopsis, written report and video presentation based on your results. These are marked by two examiners.     


CH6355: Prosiect

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH6355
External Subject Code 100417
Number of Credits 40
Level L6
Language of Delivery Welsh
Module Leader Professor Damien Murphy
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

Mae'r modiwl hwn yn cynnwys prosiect ymchwil dan oruchwyliaeth dros ddau semester. Gall hyn fod mewn unrhyw faes o gemeg ymarferol neu ddamcaniaethol, gan gynnwys prosiectau addysgiadol ac adolygu llenyddiaeth.  

Neilltuir goruchwylwyr yn unol â dewisiadau’r myfyriwr cyn belled ag y bo modd.  

Mae myfyrwyr yn paratoi crynodeb ym maes eu hymchwil, ac adroddiad ysgrifenedig a chyflwyniad fideo yn seiliedig ar eu canlyniadau.  

On completion of the module a student should be able to

Disgrifio a chyflwyno amcanion, dulliau, a chanlyniadau prosiect ar lafar ac yn ysgrifenedig.  

• Adalw a chyfathrebu data, canfyddiadau, a gweithdrefnau o amrywiaeth o ffynonellau.  

• Dadansoddi pwnc i roi trafodaeth ac asesiad beirniadol o'r materion arwyddocaol.  

• Creu a gweithredu cynllun gwaith cymhleth tuag at nod. 

• Ymchwilio i'r llenyddiaeth i hyrwyddo nodau ymchwil a dylunio protocolau arbrofol. 

• Dadansoddi a dehongli canfyddiadau a defnyddio'r rhain i ragfynegi ymddygiad i lywio gwaith yn y dyfodol.  

How the module will be delivered

Ymchwiliad ymchwil annibynnol, a oruchwylir gan aelod o staff academaidd neu ei enwebai o grŵp ymchwil.  

Skills that will be practised and developed

Sgiliau deallusol: 

 

  • Adnabod, diffinio a dadansoddi materion a syniadau cymhleth, gan arfer barn feirniadol wrth werthuso ffynonellau gwybodaeth  

  • Dadansoddi pwnc ar lefel uwch, a thrafod ac asesu’n feirniadol y materion arwyddocaol;  

 

Sgiliau sy’n benodol i gemeg: 

 

  • Cynllunio a chynnal ymchwiliad gwreiddiol ar bwnc cemeg; 

  • Chwilio am wybodaeth yn y llenyddiaeth, a’i dethol, gan drafod y llenyddiaeth yn feirniadol yng nghyd-destun y prosiect a gyflawnir;  

  • Cynnal ymchwiliad estynedig yn annibynnol ar bwnc cemeg;   

  • Cofnodi'r holl nodiadau gwaith mewn modd priodol, gan gynnwys cyfeiriadau at wybodaeth am risgiau a pheryglon, lle bo hynny'n berthnasol; 

  • Cynllunio a llunio adroddiad manwl mewn fformat safonol ar bob agwedd o'r prosiect;  

 

Sgiliau cyflogadwyedd:    

  

Cyflwynir y modiwl hwn ac mae'n cyd-fynd â'r Rhinweddau Graddedigion Prifysgol canlynol: 

 

  • Cyfrannu’n gadarnhaol ac yn effeithiol wrth weithio mewn tîm, ac yn gwneud gwahaniaeth o’r dechrau  

  • Arddangos brwdfrydedd, a’r gallu i ysgogi eu hunain a dylanwadu’n gadarnhaol ar eraill trwy gyfrifoldebau a gytunwyd arnynt mewn cyfarfod.  

  • Dangos parch at swyddogaethau pobl eraill a chydnabod cyfyngiadau eu sgiliau/profiad eu hunain.  

  • Gwrando ar eraill ac ystyried eu safbwyntiau.  

  • Cyfathrebu syniadau cymhleth yn effeithiol i gynulleidfaoedd amrywiol.  

  • Cyfrannu at drafodaethau, trafod a chyflwyno’n effeithiol  

  • Ystyried eu cyfrifoldebau moesegol, cymdeithasol ac amgylcheddol personol a phroffesiynol  

  • Arddangos gonestrwydd, dibynadwyedd a gallu personol a phroffesiynol  

  • Cofio am Argyfwng yr Hinsawdd a Nodau Cynaliadwy’r Cenhedloedd Unedig  

  • Nodi, diffinio a dadansoddi materion a syniadau cymhleth, gan arfer barn feirniadol wrth werthuso ffynonellau gwybodaeth.  

  • Arddangos chwilfrydedd deallusol a cheisio meithrin gwybodaeth a dealltwriaeth. 

  • Ymchwilio i broblemau a chynnig datrysiadau effeithiol, myfyrio a dysgu o lwyddiannau a methiannau.  

  • Creu syniadau gwreiddiol a chymhwyso ffordd greadigol, llawn dychymyg a dyfeisgar o feddwl wrth ymateb i anghenion a phroblemau a nodwyd.  

  • Cymryd yr awenau wrth weithredu ar eu syniadau eu hunain a syniadau eraill, cydbwyso’r risgiau a’r canlyniadau posib a gwneud i bethau ddigwydd.  

  • Bod yn hyderus wrth ddilyn llwybr gyrfa hyfyw a gwobrwyol mewn entrepreneuriaeth.  

  • Deall sefydliadau, eu rhanddeiliaid, a'u heffaith ar yr economi  

  • Mynd ati’n bwrpasol i fyfyrio ar eich astudiaethau eich hun, eich cyflawniadau a’ch hunaniaeth.  

  • Arddangos gwydnwch, hyblygrwydd a chreadigrwydd i ddelio â heriau, a bod yn agored i newid  

  • Nodi a chyfleu eu sgiliau, eu gwybodaeth a’u dealltwriaeth eu hunain yn hyderus ac mewn amrywiaeth o gyd-destunau.  

  • Ystyried technolegau, cyfleoedd a syniadau newydd, gan ddatblygu gwybodaeth a phrofiad i wneud penderfyniadau gwybodus am eu dyfodol eu hunain  

  • Gosod nodau uchelgeisiol ar gyfer datblygiad personol a phroffesiynol parhaus, cynllunio’n effeithiol ac ymroi i ddysgu gydol oes. 

 

  

Nodweddion Graddedig - Asesiad:    

  

Crynodeb o’r prosiect 

  • Nodi, diffinio a dadansoddi materion a syniadau cymhleth, gan arfer barn feirniadol wrth werthuso ffynonellau gwybodaeth. 

  • Nodi a chyfleu eu sgiliau, eu gwybodaeth a’u dealltwriaeth eu hunain yn hyderus ac mewn amrywiaeth o gyd-destunau. 

 

Asesiad ymarferol 

  • Nodi, diffinio a dadansoddi materion a syniadau cymhleth, gan arfer barn feirniadol wrth werthuso ffynonellau gwybodaeth.  

  • Nodi a chyfleu eu sgiliau, eu gwybodaeth a’u dealltwriaeth eu hunain yn hyderus ac mewn amrywiaeth o gyd-destunau. 

 

Cyflwyniad 

  • Cyfathrebu syniadau cymhleth yn effeithiol i gynulleidfaoedd amrywiol.  

  • Nodi, diffinio a dadansoddi materion a syniadau cymhleth, gan arfer barn feirniadol wrth werthuso ffynonellau gwybodaeth.  

  • Nodi a chyfleu eu sgiliau, eu gwybodaeth a’u dealltwriaeth eu hunain yn hyderus ac mewn amrywiaeth o gyd-destunau. 

 

Traethawd estynedig 

  • Cyfathrebu syniadau cymhleth yn effeithiol i gynulleidfaoedd amrywiol.  

  • Nodi, diffinio a dadansoddi materion a syniadau cymhleth, gan arfer barn feirniadol wrth werthuso ffynonellau gwybodaeth.  

  • Nodi a chyfleu eu sgiliau, eu gwybodaeth a’u dealltwriaeth eu hunain yn hyderus ac mewn amrywiaeth o gyd-destunau. 

Nodau Datblygu Cynaliadwy:     

  

Cyflwynir y modiwl hwn ac mae'n cyd-fynd â gweithio tuag at y Nodau Datblygu Cynaliadwy canlynol:  

 

Nod 4: Sicrhau addysg gynhwysol a theg o safon a hyrwyddo cyfleoedd dysgu gydol oes i bawb 

 

Nod 8: Hyrwyddo twf economaidd cynaliadwy, cynhwysol a chynaliadwy, cyflogaeth lawn a chynhyrchiol, gwaith gweddus i bawb 

 

Nod 9: Adeiladu seilwaith gwydn, hyrwyddo diwydiannu cynhwysol a chynaliadwy a meithrin arloesedd 

 

Nod 12 . Sicrhau patrymau defnydd a chynhyrchu cynaliadwy  

 

Nod 13: Cymryd camau gweithredu brys er mwyn mynd i’r afael â newidiadau yn yr hinsawdd ac effeithiau’r rhain. 

 

Nod 14: Cadw a defnyddio'r cefnforoedd, y moroedd ac adnoddau morol ar gyfer datblygu cynaliadwy  

 

Nod 15: Amddiffyn, adfer a hyrwyddo defnydd cynaliadwy o ecosystemau daearol, rheoli coedwigoedd yn gynaliadwy, mynd i’r afael â diffeithdiro, atal a gwyrdroi diraddiad tir ac atal colli bioamrywiaeth. 

 

Nod 17 . Cryfhau'r dulliau o weithredu ac adfywio'r Bartneriaeth Fyd-eang ar gyfer Datblygu Cynaliadwy

How the module will be assessed

Bydd y modiwl yn cael ei asesu ar sail ymgysylltu/perfformiad yn ystod y prosiect a thrwy waith cwrs, gan gynnwys adroddiad ysgrifenedig a chyflwyniad fideo o'r prosiect.  

 

Y CYFLE AR GYFER AILASESIAD YN Y MODIWL HWN:  

 

Dim ond ar y ddealltwriaeth nad ydych wedi methu mwy o gredydau nag a nodir yn y rheol ailsefyll a fabwysiadwyd gan eich rhaglen y caniateir cyfleoedd ar gyfer ailasesiad.  Os yw swm y credydau yr ydych wedi’u methu yn fwy na'r hyn a ganiateir gan y rheol ailsefyll berthnasol, mae’n bosibl y cewch ganiatâd i ail-wneud eich astudiaethau os ydych o fewn y trothwy a osodwyd ar gyfer y rheol Ail-wneud a fabwysiadwyd gan eich rhaglen.   

 

Byddwch yn cael gwybod a ydych yn gymwys i ailsefyll/ail-wneud unrhyw fodiwlau ar ôl cyfarfod y Bwrdd Arholi yn ystod cyfnod yr haf.  

 

Cynhelir pob asesiad ailsefyll yn ystod y cyfnod Arholi cyntaf sydd ar gael ar ôl y Bwrdd Arholi.  

 

Bydd ailasesiad yn cynnwys ymgais bellach i gyflwyno adroddiad a/neu gyflwyniad llafar, yn dibynnu ar y rhannau hynny a gyfrannodd at fethiant ar y cyflwyniad gwreiddiol. 

 

Fel arfer ni fydd yn bosibl ymestyn neu ailadrodd gwaith arbrofol fel rhan o ailasesu.  

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Crynodeb N/A
Practical Skills Assessment 20 Cyfraniad deallusol a / neu ymarferol N/A
Presentation 20 Cyflwyniad Fideo N/A
Dissertation 40 Adroddiad Ysgrifenedig N/A

Syllabus content

 

Mae'r modiwl hwn yn cynnwys prosiect ymchwil dan oruchwyliaeth.  

 

Gall hyn fod mewn unrhyw faes o gemeg ymarferol neu ddamcaniaethol, gan gynnwys prosiectau addysgiadol ac adolygu llenyddiaeth.  

 

Neilltuir goruchwylwyr yn unol â dewisiadau’r myfyriwr cyn belled ag y bo modd.  

 

Mae myfyrwyr yn paratoi crynodeb o’r prosiect, adroddiad ysgrifenedig a chyflwyniad fideo yn seiliedig ar eu canlyniadau. Caiff y rhain eu marcio gan ddau arholwr.     


CH8302: Advanced Organometallic and Coordination chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8302
External Subject Code 101389
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Dr Angelo Amoroso
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module will build upon concepts introduced at level 5 and develop them to address more advanced bonding schemes for metal-ligand and metal-metal interactions. Furthermore, qualitative and quantitative spectroscopic and magnetic properties of octahedral, tetrahedral and lower symmetry co-ordination complexes will be discussed, thus allowing a detailed analysis of the electronic state of the metal centre. 

The final part of the module deals specifically with organotransition metal chemistry, covering structure and bonding, reaction mechanisms, and catalysis. 

On completion of the module a student should be able to

Knowing

  • Describe the nature of orbital interactions in metal-ligand and metal-metal examples 
  • Be aware of spectroscopic and magnetic methods available to probe the nature and properties of metal containing complexes. 
  • Demonstrate an awareness of the potential applications of metal complexes. 
  • and predict properties resultant from the orbital overlap. 

Acting

  • Predict the physical properties resultant from the orbital overlap in varying complexes  
  • Interpret physical data and justify observations by predicting structure and/or by using models of orbital overlap 
  • Recognise bonding/structure relationships in transition metal mediated reactions. 

Being

  • Apply knowledge to unseen ligand types and predict behaviour. 
  • Be aware of the underlying physical processes affecting spectroscopic observations.  
  • Relate measured quantities to structure for unseen molecules. Explain observed trends and predict behaviour.  

How the module will be delivered

Content will be delivered primarily using lectures (22 h across one semester, equating to two lectures per week). In addition, lectures will include worked problems and informal ad hocformative tests. This will address the learning outcomes under the ‘Knowing’ heading, while examples presented will show students how they may also demonstrate their achievement of the ‘Acting’ learning outcomes. 

Workshops (2 x 1 h, two formative, one summative) will be used to enhance and assess problem-solving skills related to the retrieval and analysis of data. 

Tutorials (2 x 1 h, formative) will allow tutors to monitor and guide the progress of students in meeting all learning outcomes. 

Skills that will be practised and developed

Chemistry-specific skills will be focused on developing student’s abilities to analyse the nature of the bonding with a transition metal complex. By assigning oxidation state and metal centre geometry, an appropriate MO diagrams may be produced. Students will develop an understanding of ligand nature and their interaction with the metal centre. Affects on reactivity of the complex (redox or chemical bond formation) will be discussed. 

Metal-metal orbital interactions may  be discussed, allowing the further development of the students understanding of multiple bonding.  

Students will develop the necessary skills to identify the appropriate physical techniques to analyse and assess the bonding (and magnetic) interactions in transition metal complexes. 

Specifically, the student will have the required skills to be able to: 

  1. Analyse the structure of unseen organometallic complexes and predict their potential behavior with respect to redox reactions or the activation of small organic molecules. 
  2. Use crystal field theory and other symmetry derived arguments to derive MO diagrams for low symmetry complexes and M-M bonding. 
  3. Investigate and assign the geometry of novel co-ordination complexes; To quantify the ligand field splitting and racah B and so determine the nature of new ligands.  
  4. Investigate and assign the nature of magnetic interactions in magnetically non-dilute materials; To know how to measure J, understand its meaning and be able to rationalize the results. 

How the module will be assessed

The module is summatively assessed via in course assessments.

There is no examination for this module.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Advanced Organometallic and Coordination chemistry N/A

Syllabus content

The syllabus will draw from a range of topics, chosen to exemplify orbital interactions and resulting physical and chemical properties. These topics will allow the development of the student’s ability to utilise spectroscopic methods to investigate the nature of the materials. These topics may include: 

Structure and bonding in organometallic chemistry 

Description of bonding models for π-acceptor and π-donor ligands, including CO, alkenes (Dewar Chatt Duncanson model), NO+, RO-and NR2-; Physical evidence and consequences of bonding, applications of infrared spectroscopy. 

Other σ-bonding ligands, e.g. H-, and alkyl ligands. 

Metal carbonyl complexes, preparation, properties and structure. 

Bonding and structure in metal alkene complexes including conjugated anionic and polyalkene ligands and influences upon reactivity. 

Metal carbon multiply bonded systems, carbene (Fischer type) and alkylidene/alkylidyne (Schrock type) compounds. Examination of bonding models for these systems and relationships with experimentally observed reactivity. 

Transition metal hydrides and dihydrogen complexes. 

Spectroscopic techniques of study of organometallic compounds (e.g. NMR etc.). 

Mechanistic organometallic chemistry 

Classic reaction pathways of organometallic compounds, introduction to catalytic cycles 

Oxidative additions, reductive eliminations, migratory insertions, hydrogen migrations. 

Reactions of metal-alkene, metal-CO and metal-alkyl complexes relevant to homogeneous catalysis and a discussion of mechanisms (e.g. polymerisation, metathesis, cross-coupling, asymmetric catalysis). 

Metal-metal bonding 

Syntheses, structures and metal-metal bonding in transition metal dimers, trimers and larger clusters. 

Describe interactions in multiple metal-metal bonds. 

Electronic properties of stacked platinum complexes (e.g. Magnus’s salt) and anisotropic conduction. 

Mixed-valence species 

Robin-Day classification 

Study of redox processes by cyclic voltammetry; IVCT and π- π*, evaluating electronic coupling. 

UV-vis Spectroscopy 

Assigning transitions and calculating Δ and racah B for d1-d9 HS and d6 LS. 

Line width and signal intensity in d-d transition. 

Magnetochemistry 

Orbital contributions: 

Nature of A and E term complexes and TIP; 

Nature of T terms: Kotani plots and their derivation. 

Magnetic properties of lower symmetry complexes:TBP, trigonal and trigonal prismatic. 

Organometallic examples. 

Elucidation of geometry utilising magnetic data. 

Effect of paramagnetism on NMR; contact shift; shift reagents; Evans’ method. 

Non-dilute systems. 

Multimetallic systems. 

Exchange mechanisms: for design or for rationalising systems. 

Exchange integral: measuring for d9 systems. 

Complexes with co-ordinated radicals: 

Innocent and non-innocent ligands. 

Examples considering magnetic, electrochemical and EPR properties. 


CH8303: Advanced Synthetic Strategies (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8303
External Subject Code 101389
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Professor Thomas Wirth
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module shows: 1) how a target synthesis may be designed using retrosynthetic analysis; and 2) how modern reactions can be applied to the synthesis of target organic molecules.

On completion of the module a student should be able to

  • understand the use of transition metal catalysts in organic synthesis with emphasis on stereoselective transformations;
  • perform a retrosynthetic analysis and propose a forward synthesis for any given target molecule;
  • design synthetic routes for target molecules based on an understanding of chemical reactivity and knowledge of organic reactions as taught in modules CH4103 and CH4203;
  • design syntheses of target organic molecules, including the use of protective groups as required for compatibility of reactivity.

How the module will be delivered

22 x 1 h Lectures, 3 x 1 h Workshops, 2 x 1 h Tutorials

Skills that will be practised and developed

Advanced organic synthesis methods: The student will practice retrosynthetic analyses in a complex setting.

Development of the skill to include advances oxidation strategies (Epoxidations, dihydroxylations) in total syntheses and retrosyntheses.

Development of stereochemical thinking by practicing asymmetric oxidations.

How the module will be assessed

The module is summatively assessed via in course assessments.

There is no examination for this module.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Advanced Synthetic Strategies (Study Abroad) N/A

Syllabus content

Retrosynthetic analysis

Introduction to disconnections and the logic of synthesis

C-X disconnections – halides, ethers, sulphides and amines and 1,2- & 1,3-difunctionalised compounds

C-C disconnections and synthesis using carbonyl group, including alkene synthesis, enolate alkylation selectivity

Synthesis of 1,3-, 1,4- and 1,5-dicarbonyl compounds

Use of protecting groups when chemoselectivity issues arise

Manipulation of double bonds, ring opening, ring expansion and ring formation techniques

 

Pericyclic reactions

Electrocyclic reactions, Cycloadditions, Sigmatropic rearrangements (Diels-Alder reaction, 1,3-dipolar cycloaddition, Claisen rearrangement etc.)

 

Palladium-catalysed coupling methods

Disconnection for the synthesis of polyunsaturated systems

Definitions of Heck, Suzuki-Miyaura, Kumada, Negishi and Sonogashira methods

Catalytic cycle summary and key differences within these

Perspective on utility, practicalities etc.

Selected applications in synthesis, with emphasis on the retrosynthetic features and stereoselective synthesis

Precursor synthesis where appropriate

 

Metathesis

Definition and emphasis on catalyst types for both ring closure (ene-ene, ene-yne and yne-yne) and cross metathesis; experimental methods; brief mention of utility in polymer synthesis and total synthesis

 

Modern oxidative transformations

Epoxidations (Sharpless Asymmetric Epoxidation, Jacobsen Epoxidation)

Dihydroxylation; AD-mix; related osmylation methods; synthetic utility (examples).


CH8304: Quantum and Statistical Mechanics of Molecules and Solids (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8304
External Subject Code 101050
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Professor James Platts
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

The module describes the fundamental concepts in quantum and statistical mechanical description of molecules and solids. Starting from solution of the Schrödinger equation for model systems, quantum mechanical methods for approximate description of molecular electronic structure, and their applications, will be discussed. Statistical mechanics will be based around the definition of partition functions, and will employ such definitions in discussion of thermodynamics and kinetics. Extension of quantum mechanics to the solid state will lay the basis for of band theory description of the electronic structure of metals, semi-conductors and insulators.

On completion of the module a student should be able to

Knowing(these are things that all students will need to be able to do to pass the module):

 

  • Demonstrate awareness of methods for description of electronic structure of molecules and solids.
  • Describe means to relate molecular to macroscopic properties using the techniques of statistical mechanics.

 

Acting(Performance in this area will enable students to achieve more than a basic pass):

 

  • Evaluate results of electronic structure calculations, critically assess their performance and extract chemically relevant properties.
  • Calculate thermodynamic and kinetic properties of molecular systems from knowledge of molecular properties.
  • Understand and predict key properties of materials based on a band structure description of their electronic structure.

 

Being(Performance in this area will enable students to achieve more than a basic pass):

 

Retrieve and communicate data, findings and procedures from a variety of sources (literature, electronic databases, experiments/calculations).

How the module will be delivered

Content will be delivered primarily using lectures (22 h across one semester, equating to two lectures per week). In addition, lectures will include worked problems and informal ad hocformative tests. This will address the learning outcomes under the ‘Knowing’ heading, while examples presented will show students how they may also demonstrate their achievement of the ‘Acting’ learning outcomes.

 

Workshops (3 x 1 h, two formative, one summative) will be used to enhance and assess problem-solving skills related to the retrieval and analysis of data.

 

Tutorials (2 x 1 h, formative) will allow tutors to monitor and guide the progress of students in meeting all learning outcomes.

Skills that will be practised and developed

Chemistry-specific skills will be focused on applying ideas from fundamental physical chemistry to understand how modern descriptions of the electronic structure of molecules and solids are constructed and applied to reach a unified picture of molecular properties. Students will develop a detailed understanding of how properties of molecules and materials are related to their electronic structure, and how these properties are related to observed macroscopic behaviour. The module will also involve a large element of problem solving using both numerical and algebraic techniques, based around real examples of theoretical methods.

How the module will be assessed

The module is summatively assessed via in course assessments.

There is no examination for this module.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Quantum and Statistical Mechanics of Molecules and Solids (Study Abroad) N/A

Syllabus content

Quantum mechanics: Schrödinger equation, Born-Oppenheimer approximation; Exact solutions for model problems; electron spin and the Pauli principle; Coulomb and exchange energies; Variation theorem, approximate wavefunctions and energies; LCAO approximation, Slater determinants and basis sets; Hartree-Fock and self-consistent field approach; Electron correlation: Post-HF and density functional theory methods; potential energy surfaces and chemical properties.

 

Statistical mechanics: Review of basic concepts, probability, kinetic theory of gases, microstates, Boltzmann distribution; Definition of partition functions for translational, rotational and vibrational degrees of freedom Thermodynamics from partition functions: internal energy, entropy and heat capacity; role of partition functions in rate constants derived from transition state theory.

 

Band theory: Band structure and its relationship to the electronic structure of solids; Band structure at interfaces; Periodic quantum chemistry approach for theoretical analysis of solid state structure; Bloch functions for wavefunctions for periodic systems; Reciprocal space and use of sampling to determine approximate band structures.


CH8305: Macromolecules of Life (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8305
External Subject Code 100948
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Dr James Redman
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module concerns the structure, chemistry and analysis of proteins and nucleic acids. The module illustrates how fundamentals of chemical structure and reaction mechanisms can be applied to the physical and functional properties of proteins and nucleic acids. Real-life applications in medicine and industry will be outlined. Students will learn about the range of analytical and structure determination techniques that can be applied to biological macromolecules. The principles of modern methods for DNA synthesis, amplification and sequencing will be elucidated. Principles of enzyme catalysis and kinetics will be discussed, together with an overview of the roles played by cofactors. The processes of transcription and translation will be described with an overview of how molecular biology enables production of new proteins.  

On completion of the module a student should be able to

• Explain the roles of macromolecules in the chemistry of life. 

• Predict and explain the function and reactivity of biological macromolecules in terms of chemical structure and reaction mechanism. 

• Select experimental strategies to synthesise and analyse biological macromolecules. 

 

How the module will be delivered

Content will be delivered primarily using lectures (22 h across one semester, equating to two lectures per week). Lectures will include worked problems representative of exam questions.

Tutorials (2 x 1 h, formative) will give the opportunity to practice solving problems and interpretating experimental observations. 

Skills that will be practised and developed

Chemistry-specific skills will be focused on applying ideas from functional group chemistry and mechanistic organic chemistry to understand how the structure of proteins and nucleic acids permit them to perform their biological function. Student will learn how to select appropriate techniques for synthesis and analysis of biological macromolecules. Students will also gain familiarity with computer-based methods for searching, retrieving and visualising protein and nucleic acid sequences and structures from on-line databases. 

How the module will be assessed

Formative assessment: Lectures will include the opportunity to attempt problems based on exam questions with immediate feedback provided in oral form. Students will be provided with problems to attempt in advance of the tutorials. Feedback will be provided orally during the tutorial. This will prepare students to tackle problem-solving exercises in the examination and professional practice.

Summative assessment: An open book exercise will test students’ ability to demonstrate their knowledge of the syllabus content, retrieve electronic resources and their ability to apply the concepts covered to unseen problems. 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

Students who are permitted by the Examining Board to be reassessed in this module during the same academic session will undertake resit coursework during the Resit Examination Period. 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Macromolecules of Life (Study Abroad) N/A

Syllabus content

Overview of protein structure; Ramachandran plots and secondary structure; Tertiary and quaternary structure; Protein structure prediction; Introductory NMR and mass spectrometric characterization of proteins. 

Principles of protein function; Binding and catalysis. Myoglobin and hemoglobin; Physical basis of enzyme catalysis including the role of cofactors, Michaelis-Menten kinetics; Mechanisms of enzyme inhibition; Simple examples of enzyme-catalyzed transformations. 

Structure, biophysical properties and chemistry of nucleotides (DNA and RNA); DNA synthesis, amplification and sequencing; DNA-based technologies and their applications. 

Transcription and translation; mRNA and tRNA synthesis; The genetic code and the molecular basis of ribosomal protein synthesis. 


CH8307: Advanced Spectroscopy and Diffraction (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8307
External Subject Code 100417
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Professor Kenneth Harris
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

 

The module explains how detailed information about structure, stereochemistry, and the behaviour of chemical species in solution and in the solid state can be obtained by using luminescence spectroscopy, electron paramagnetic resonance (EPR) spectroscopy, and diffraction techniques (specifically X-ray diffraction, neutron diffraction and electron diffraction, as well as electron microscopy). 

On completion of the module a student should be able to

 

Luminescence Spectroscopy  

 

  • Describe the fundamental principles of photoluminescence spectroscopy and the different types of electronically excited states associated with organic molecules and inorganic d- and f-block coordination complexes.       

  • Sketch Jablonski energy level diagrams for different classes of compound and apply knowledge of photoexcited state molecules to various applications.   

 

EPR Spectroscopy 

   

  • Sketch energy level diagrams for electron-nuclear spin systems and predict the appearance of EPR spectra of organic radicals, including the multiplicity of resonance lines.   

  • Extract spin Hamiltonian values from experimental spectra and correlate with chemical structure.   

 

Diffraction Techniques  

   

  • Explain the scope and limitations of X-ray diffraction, neutron diffraction, electron diffraction and electron microscopy techniques in the study of structural properties of solids.   

  • Formulate the optimum experimental strategy for exploring specific aspects of solid-state structure.  

 

How the module will be delivered

 

21 Lectures, with seven lectures allocated to each of the three components of the module (Luminescence Spectroscopy, EPR Spectroscopy and Diffraction Techniques). Each lecture is held “in person” in a lecture theatre. The duration of each lecture is 50 minutes. Each lecture is recorded, with the recording made available to students on Learning Central on the same day as the lecture.   

 

Three Formative Workshops, with one formative workshop allocated to each of the three components of the module (Luminescence Spectroscopy, EPR Spectroscopy and Diffraction Techniques). The duration of each formative workshop is 50 minutes. Each formative workshop is held as a whole-class activity in a lecture theatre. Each formative workshop is recorded, with the recording made available to students on Learning Central on the same day as the workshop.   

 

Skills that will be practised and developed

Interpretation of EPR spectra for paramagnetic species in solution and in the solid state.

Formulating optimum experimental strategies (involving the use of one or more of the X-ray diffraction, neutron diffraction, electron diffraction or electron microscopy techniques) for exploring specific aspects of solid-state structure.

Ability to select appropriate techniques for determination of structure in solution or in the solid state for a range of chemical situations, and to assess the advantages/disadvantages for each particular purpose.

How the module will be assessed

The module is summatively assessed via in course assessments.

There is no examination for this module.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Advanced Spectroscopy and Diffraction (Study Abroad) N/A

Syllabus content

The module is sub-divided into the following three components, which have essentially equal weight:

 

Luminescence Spectroscopy

Selection rules; quantized description; Jablonski diagrams.

Stokes shift; quantum yield; lifetimes.

Fluorescence; phosphorescence.

Types of chromophores; effect of structure on emission; donor-acceptor.

Energy transfer: Dexter versusFörster.

Quenching pathways: O2; photoinduced electron transfer.

Applications to coordination complexes: TM; lanthanides.

Chemosensors; imaging; LEDs; PDT.

Chemoluminescence; bioluminescence; electroluminescence.

 

EPR Spectroscopy

Basic principles of Electron Paramagnetic Resonance (EPR).

Origin and significance of the electron Zeeman and nuclear Zeeman effects.

Derivation of simple spin Hamiltonian for a two spin system (S= ½, I= ½).

Interaction of the electron with its environment – anisotropy and symmetry effects in EPR spectra.

Applications of EPR to characterize paramagnetic systems.

Analysis and interpretation of EPR spectra of organic radicals in solution, as well as main group radicals and transition metal ions in frozen solution.

Interpretation of spin Hamiltonian parameters gand A(hyperfine) values.

 

Diffraction Techniques

 

Fundamentals:

Properties of X-rays.

Properties of electron beams.

Properties of neutron beams.

Production of X-rays and other radiation (conventional sources and synchrotron radiation).

Fundamentals of diffraction by crystalline solids.

 

Applications, Scope and Limitations of Techniques:

X-Ray diffraction (XRD): applications of X-ray diffraction, single-crystal versuspowder X-ray diffraction, advantages of using synchrotron radiation, limitations of X-ray diffraction.

Neutron diffraction (ND): applications of neutron diffraction, neutron diffraction versusX-ray diffraction.

Electron diffraction and electron microscopy: electron diffraction (ED), transmission electron microscopy (TEM), scanning electron microscopy (SEM), low energy electron diffraction (LEED).


CH8308: Bioinorganic Chemistry (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8308
External Subject Code 101043
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Professor Ian Fallis
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

Many key processes in biology are enabled by metal ions such as calcium, iron, copper and zinc. In this module the biological functions of a wide range of elements are examined with a particular focus upon the functions of metal ions and their catalytic roles in biology. The module will correlate the fundamental coordination chemistry of metal ions to the wide range of redox, Lewis acidic and structural roles they play in biological structures. The roles of metal ions in selected important drugs will also be explored.

On completion of the module a student should be able to

Knowing (these are things that all students will need to be able to do to pass the module):

  • Describe the range of functions of metal ions in biological systems.
  • Classify metalloenzymes by reaction type and illustrate with relevant examples.
  • Explain types and classes of metal ligand interactions in metalloenzymes.

Acting (Performance in this area will enable students to achieve more than a basic pass):

  • Classify the types of metalloproteins and co-factors that incorporate transition metal and main group ions.
  • Understand from an evolutionary perspective the need for transition metal ions in biological systems.

Being (Performance in this area will enable students to achieve more than a basic pass):

 

  • Retrieve and communicate data, findings and procedures from a variety of sources (literature, electronic databases).
  • Understand the mechanisms of metalloenzyme promoted chemical transformations.
  • Understand and illustrate the mode of action of metal containing drugs.

How the module will be delivered

Content will be delivered primarily using lectures (22 h across one semester, equating to two lectures per week). In addition, lectures will include worked problems and informal ad hoc formative tests. This will address the learning outcomes under the ‘Knowing’ heading, while examples presented will show students how they may also demonstrate their achievement of the ‘Acting’ learning outcomes.

 

Workshops (3 x 1 h, one formative, two summative) will be used to enhance and assess the basic knowledge from the lecture material.

 

Tutorials (2 x 1 h, formative) will allow tutors to monitor and guide the progress of students in meeting all learning outcomes.

Skills that will be practised and developed

  • Classification of complex bioinorganic systems;
  • Analysis and understanding of the mechanisms in bioinorganic chemical systems;
  • Correlation of fundamental chemical properties of the elements with their roles in biological systems.

How the module will be assessed

The module is summatively assessed via in course assessments.

There is no examination for this module.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Bioinorganic Chemistry (Study Abroad) N/A

Syllabus content

All elements are mandatory

 

•           Inorganic’ Elements in biology, summary and overview

•           Amino acids, peptides and nucleic acids as ligands

•           Coordination chemistry of biological molecules

•           Roles, choice, transport, and storage of metal ions

•           Metalloenzymes - classification

•           Entatic State Hypothesis

•           Synthetic Analogue Approach

•           Catalytic antibodies - ferrochelatase

•           Non-redox enzymes (hydrolases, phosphatases)

•           Dioxygen – generation, uptake transport and storage, Fe and Cu; heme catalysts

•           Electron transport

•           Fe/S & non-heme Fe and redox

•           Photosynthesis - Ca/Mn, Mg – light harvesting and water splitting, Plastocyanins, Azurins

•           Protective enzymes – SODs, catalase, peroxidase

•           Bioorganometallic Chemistry-B12, CO

•           Hydrolases, hydrogenases, nitrogenases, reductases

•           Structural roles of metals in biology

•           Biomineralisation


CH8310: Heterogeneous Catalysis (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8310
External Subject Code 100417
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Professor Stuart Taylor
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module illustrates the wide range of heterogeneous catalysis and its relevance to industry and environmental matters, describes the mechanisms involved in catalysis at the molecular level, and illustrates the techniques available for the study of these processes.

The role of heterogeneous catalysts and their uses in environmental and chemical manufacturing applications will be described and discussed, processes will include oxidation reactions, car exhaust treatment and acid catalysed reactions. Examples of different types of catalysts, such as supported metals, metal oxides and zeolites, will all be introduced for specific applications.

The typical properties and preparation of a heterogeneous catalyst will be presented, along with important features and catalyst characteristics. Performance of a catalyst will be evaluated and quantitative descriptors introduced, as will catalyst deactivation.

Mechanisms of heterogeneous catalysts will be considered, and the different models advanced to account for heterogeneously catalysed reactions will be introduced. These include Langmuir-Hinshelwood, Eley-Rideal and Mars van Krevelen models.

Details of how catalysts are used in different reactors will be presented, and the importance of these will be discussed. The different physical forms of the catalysts will also be considered in the context of different reactors.

On completion of the module a student should be able to

Knowing (these are things that all students will need to be able to do to pass the module):

  • Demonstrate awareness of the application of heterogeneous catalysts for a range of modern processes and reactions.
  • Demonstrate understanding of structure, function and activity of heterogeneous catalysts.
  • Describe the fundamental principles and mechanisms of heterogeneous catalysts.

Acting (Performance in this area will enable students to achieve more than a basic pass):

  • Evaluate experimental data from performance of heterogeneous catalysts and relate this to catalyst characteristics.
  • Propose mechanisms for heterogeneously catalysed transformations covering a wide range of chemistry.
  • Propose key catalyst characteristics to effectively catalyse a wide range of reactions.

Being (Performance in this area will enable students to achieve more than a basic pass):

  • Critically assess data relating to catalyst performance, communicating key concepts and characteristics, and suggest potential catalysts for unseen reactions.

How the module will be delivered

Content will be delivered primarily using lectures (22 h across one semester, equating to two lectures per week). In addition, lectures may  include some worked problems and informal ad hoc formative tests. This will address the learning outcomes under the ‘Knowing’ heading, while examples presented will show students how they may also demonstrate their achievement of the ‘Acting’ learning outcomes.

 Workshops (3 x 1 h, two formative, one summative) will be used to enhance and assess problem-solving skills related to the retrieval and analysis of information and data.

Skills that will be practised and developed

Chemistry-specific skills will be focused on applying ideas introduced in earlier modules, these will include kinetics, thermodynamics, solid state chemistry and surface chemistry. These fundamental concepts will be applied to understand heterogeneous catalysts and how they operate. Application of these fundamental principles will reinforce student’s skills in their application and understanding. Understanding the basic principles of heterogeneous catalysis will allow the student to start to select appropriate catalysts for specific target reactions, and appreciate how catalysts could be applied for vital industrial and environmental reactions.

An appreciation of the wide applications of catalysts on a global scale will be gained, and this is an important insight into the modern chemical and processing industries, providing students with a competitive advantage when interacting with industry.

The module develops a number of transferable skills, such as problem solving, numeracy, retrieval and analysis of information, all of which are important for enhancing employability.

How the module will be assessed

The module is summatively assessed via in course assessments.

There is no examination for this module.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Heterogeneous Catalysis (Study Abroad) N/A

Syllabus content

The module will begin by covering the basics and applications of catalysis, effects of catalysts on reaction rates and product distribution, requirements for practical catalysts, and the design of catalysts with attention to active phases, supports and promoters.

Examples include catalysts for (i) oxidation, including catalytic combustion; (ii) water gas shift; (iii) refining processes; (iv) removal of sulfur from fuels; (v) production and use of syngas, and catalytic routes to ammonia and methanol; (vi) pollution control with particular reference to car exhaust catalysts.

The types of reactors used to apply heterogeneous catalysts will be introduced and the important features will be discussed.

A number of examples of different catalysts will be covered in case studies for a wide range of applications. An example will be the three-way catalytic converter for control of vehicle emissions Different types of heterogeneous catalysts, like zeolites, supported metals and metal oxides will be covered. These examples will present a number of different catalytic mechanisms and will include the types Langmuir-Hinshelwood, Eley-Rideal and Mars-van Krevelen.

A number of techniques used to characterise heterogeneous catalysts will be introduced.


CH8315: Structure and Mechanism in Organic Chemistry (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8315
External Subject Code 100422
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Dr Niklaas Buurma
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module outlines 1) MO theory as applied to the analysis of organic reactions, including in pericyclic reactions, 2) the techniques and approaches of physical organic chemistry that are be used to determine mechanisms of organic, bioorganic and catalytic reactions as well as the properties of reaction intermediates, even when they may not be directly observable.

On completion of the module a student should be able to

Knowing (these are things that all students will need to be able to do to pass the module):

 

  • classify pericyclic processes
  • apply molecular orbital theory in the analysis of organic reactivity
  • describe the underlying physical basis for, and applications of, physical organic chemistry
  • apply retrosynthetic analysis to problems featuring pericyclic processes.
  • propose reaction intermediate(s) and products for pericyclic reactions;

 

Acting (Performance in this area will enable students to achieve more than a basic pass):

  • determine the outcome of pericyclic processes, including periselectivity, regioselectivity and stereoselectivity
  • propose a reasonable and falsifiable reaction mechanism for a reaction based on physical data and/or MO analysis.
  • evaluate whether a reaction mechanism is reasonable or not through an analysis in terms of frontier molecular orbital theory and through interpretation of kinetic and mechanistic data;

 

Being (Performance in this area will enable students to achieve more than a basic pass):

  • critically discuss techniques for acquiring kinetic data
  • retrieve and communicate data, findings and procedures from the literature
  • integrate previously acquired knowledge of reactivity patterns in organic chemistry with experimental and computational data to solve problems of organic reaction mechanisms
  • propose experiments and predict outcomes of experiments designed to falsify proposed reaction mechanisms

How the module will be delivered

The module is delivered as 22 one-hour lectures in combination with three one-hour workshops. During the workshops, groups of students will prepare a presentation on a research paper reporting kinetic and/or mechanistic studies. The workshop mark will be for the presentation.

Skills that will be practised and developed

On completion of the module the student will be able to 1) discuss how reaction mechanisms become accepted theory through the continuous evaluation of kinetic and mechanistic data and how such mechanisms are falsifiable theories; 2) decide which experimental techniques are most appropriate for solving problems in organic reaction mechanisms; 3) understand how the techniques of physical organic chemistry can find application in solving problems in neighbouring disciplines, such as biological chemistry and catalysis; 4) statistically analyse numerical data; 5) defend a scientific proposal using data. 6) Deliver an oral presentation on a mechanistic study.

How the module will be assessed

The module is summatively assessed via in course assessments.

There is no examination for this module.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Structure and Mechanism in Organic Chemistry (Study Abroad) N/A

Syllabus content

MO theory as applied to Non-Pericyclic Organic Reactions: The application of MO theory to various organic reactions; stereoelectronic effects.

 

MO theory as applied to Pericyclic Reactions: Cycloadditions (including Diels-Alder and dipolar cycloadditions); symmetry-allowed and symmetry-forbidden reactions, regioselectivity, stereoselectivity; sigmatropic rearrangements; 1,n hydride shifts, Cope and Claisen rearrangements; Electrocyclic reactions; Photochemical processes; Synthetic strategies involving pericyclic processes

 

Kinetics techniques in mechanistic studies: Experimental methods for the acquisition of kinetic data; Data analysis, curve fitting, statistics and error analysis; Simple rate laws; Analysis of kinetic data in terms of reaction mechanisms; Complex rate laws; Numerical integration techniques

           

Determination and Interpretation of Activation Parameters in mechanistic studies: Gibbs energies and standard states; ΔHø‡, ΔSø and ΔVø‡ and their interpretation

 

General & Specific Acid and Base Catalysis in mechanistic studies: pH rate profiles; Equations and data analysis; Mechanisms leading to general/specific acid/base catalysis

 

Linear Free Energy Relationships in mechanistic studies: Brønsted plots; Hammett plots

Use of isotopes in mechanistic studies: Isotopic Labelling; Cross-over Experiments; Primary kinetic isotope effects; Solvent isotope effects

Proposing reasonable reaction mechanisms: Application of the techniques above to proposing reasonable reaction mechanisms

From mechanism to engineering and back: Reaction scale up using kinetic and thermodynamic data; use of modern technology for kinetic, mechanistic and reaction optimisation studies; flow chemistry in kinetic studies; pH stat; feedback loops; automated reaction optimisation; AI in reaction optimisation.


CH8316: Homogeneous Catalysis (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8316
External Subject Code 100417
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Dr Paul Newman
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module will give an overview of homogeneous catalysis, and will contain material from organometallic chemistry (catalytic cycles of selected key catalytic reactions, relating the catalytic mechanisms to fundamental organometallic concepts), including industrially-relevant reactions. An overview of reaction kinetics, with a specific focus on how they can be applied to catalytic reactions, will be provided, along with material relating to chemo- and stereoselectivity.

On completion of the module a student should be able to

  • Construct catalytic cycles using fundamental organometallic reaction steps. 
  • Understand how p-block metals can be used to effect catalytic transformations. 
  • Understand how to measure and analyse kinetic data that relate to catalytic reactions. 
  • Relate kinetic data to the underlying catalytic mechanism. 
  • Propose mechanistic details by interpreting experimental data. 
  • Explain chemical- and regio-selectivity in terms of a catalytic mechanism. 

How the module will be delivered

22 x 1 h Lectures, 3 x 1 h Workshops (2 formative, 1 summative) 

Skills that will be practised and developed

Analysis of experimental data to obtain an understanding of chemical reactions. 

Interpretation of experimental data. 

Derivation of kinetic equations based upon catalytic cycles. 

Construction of catalytic cycles. 

How the module will be assessed

The module is summatively assessed via in course assessments.

There is no examination for this module.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Homogeneous Catalysis (Study Abroad) N/A

Syllabus content

Mechanistic organometallic chemistry 

Reactions of metal-alkene, metal-CO and metal-alkyl complexes relevant to homogeneous catalysis and a discussion of mechanisms (hydrogenation (transfer hydrogenation, H borrowing, Wilkinson’s substrate scope, Crabtree’s catalyst), carbonylation (hydroformylation, Monsanto, Eastman), metathesis, asymmetric catalysis). Kinetics of catalysis applied to the above-mentioned catalytic cycles.


CH8317: Engineering Biosynthesis (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8317
External Subject Code 100417
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Dr James Redman
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module concerns the engineering of biosynthetic pathways for synthesis of organic chemicals for use as pharmaceuticals, agrochemicals, flavours/fragrances and fuels. Biosynthesis enables sustainable manufacture of complex molecules in multistep routes using fermentation from renewable feedstocks under benign conditions. The combination of synthetic chemistry with biosynthesis provides an efficient avenue to novel compounds for screening as drugs. The strategies and challenges for production of organic chemicals through biosynthetic pathways will be described and illustrated with examples drawn from the biosynthesis of different classes of secondary metabolite.

On completion of the module a student should be able to

  • Propose intermediates and reaction pathways for the biosynthesis of a given metabolite.  

  • Choose strategies to engineer enzymes and metabolic pathways to produce a compound of a given structure. 

  • Retrieve, interpret and communicate data, findings and procedures relating to biosynthesis from journals and databases. 

How the module will be delivered

The module will be delivered primarily using lectures (22 h across one semester) where the principles of biosynthesis of different classes of secondary metabolite will be introduced including case studies of engineering from the literature. In addition, lectures will include worked problems and informal ad hoc formative activities.  

Workshops (two formative, one summative) will be used to enhance and assess problem-solving and literature searching skills. 

Skills that will be practised and developed

Students will practice applying the concepts of synthetic organic chemistry to enzyme catalysed biosynthetic pathways. Students will develop skills in proposing appropriate starting materials and enzymes to synthesise a given target structure. 

  Chemistry specific skills will include: 

  • Assignment of metabolites to a particular pathway, and proposal of biosynthetic intermediates and transformations;   

  • Apply strategies for modifying a biosynthetic pathway to increase yields or produce novel products;  

  • Predicting the outcome of biosynthetic processing of an unnatural substrate;   

  • Choosing appropriate synthetic substrates for biosynthetic pathways to generate novel compounds.   

  Transferable skills:  

  • Searching databases to find relevant chemical literature; 

  • Synthesising and summarising information from multiple sources; 

  • Proposing solutions to problems based on incomplete information;  

  • Presenting chemical arguments in written form. 

How the module will be assessed

Formative assessment: The first two workshops will be assessed formatively, and feedback provided either orally or in written form. This will give students an opportunity to revise the factual module content and to practice applying it to deduce and propose biosynthetic pathways. 

Summative assessment: A summatively assessed workshop in the form of an open-book exercise will test the ability to explain biosynthetic pathways, find information, propose pathways for production of previously unseen compounds, propose and interpret experiments in biosynthesis. 

  THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

The reassessment will take place during resit examination period. The reassessment will take the same form as the original assessment. 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Engineering Biosynthesis (Study Abroad) N/A

Syllabus content

Rationale for engineering pathways in primary and secondary metabolism for sustainable production of complex organic chemicals. 

Biosynthetic pathways for common classes of secondary metabolite, with examples drawn from polyketides, terpenoids, alkaloids and non-ribosomal peptides. 

Strategies for modifying enzyme selectivity and activity – rational design, screening, directed evolution approaches.  

Case studies of engineering metabolite biosynthesis. 

Reconstituting metabolic pathways in new hosts (choice of host - considerations such as precursor availability, toxicity of intermediates, compartmentalisation, PTMs of pathway enzymes, accessory proteins).  

Efficiently creating molecular diversity by combining synthetic chemistry with biosynthesis (mutasynthesis) and combinatorial biosynthesis.


CH8383: Strategies in Organic and Biological Chemistry (Exchange)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8383
External Subject Code 100422
Number of Credits 10
Level L6
Language of Delivery English
Module Leader Dr Mark Elliott
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module integrates advanced concepts from organic chemistry and biological chemistry, building on previous modules to explore the synthesis of complex organic molecules and the chemistry of biological macromolecules. 

 

The module focuses on modern synthetic transformations and retrosynthetic analysis, alongside the synthesis and analysis of nucleic acids and peptides. 

 

Students will gain an understanding of how organic chemistry principles apply to biological systems, with real-life applications in medicine and industry. 

On completion of the module a student should be able to

  • Demonstrate a comprehensive understanding of synthetic chemistry transformations, identifying nucleophilic and electrophilic sites, and recognising plausible bond-forming steps. 

  • Perform retrosynthetic analysis and plan a forward synthesis for target molecules of moderate complexity, describing the approach with correct terminology 

  • Explain the synthesis and analysis of nucleic acids and peptides, applying organic chemistry principles to biological macromolecules. 

How the module will be delivered

 

Learning activities will be a blend of lectures (22 hours) containing problem-solving formative components. Answers to given problems will be covered during lectures and/or provided videos/supplementary resources. 

Three workshops will be delivered, with a focus on developing problem-solving skills. The first two of these will be formative, with feedback provided. The final one will be summatively assessed. 

Tutorials (2 x 1 hour) will also be delivered to allow further opportunities for informal student feedback to be provided. 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Written Assignment N/A

Syllabus content

Application of organic reactions: Construction of complex molecules using multi-step synthetic pathways. 

 

Retrosynthetic Analysis: Introduction to disconnections and the logic of synthesis, including C-X and C-C disconnections. 

 

Synthesis of Dicarbonyl Compounds: Techniques for synthesising 1,3-, 1,4-, and 1,5-dicarbonyl compounds. 

 

Use of Protecting Groups: Strategies for addressing chemoselectivity issues. 

 

Pericyclic Reactions: Exploration of electrocyclic reactions, cycloadditions, and sigmatropic rearrangements. 

 

Metathesis: Definition and application of ring-closing and cross metathesis in total synthesis. 

 

Protein and nucleic acid chemistry: Principles of nucleic acid and peptide synthesis, separation and analysis. Use of mass spectrometry and HPLC for the characterisation of peptides. 

 


CH9350: Placement Experience Abroad (MChem)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH9350
External Subject Code 101043
Number of Credits 90
Level L6
Language of Delivery English
Module Leader Dr Jonathan Bartley
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module is taken by MChem students on placement abroad.  

 

The main feature will be a substantial project on a topic determined by the placement provider. Placements will be approved by the School placement coordinator.  

 

This will be carried out on a timescale appropriate for the particular placement, with duration no less than 9 months and up to 12 months.  

 

The main report will be supplemented by a short placement review, describing the particular environment of the placement. 

On completion of the module a student should be able to

 

• Describe and present the objectives, methods and outcomes of a project in oral and written form. 

• Retrieve and communicate data, findings, and procedures from a variety of sources. 

• Analyse a topic to give a discussion and critical assessment of the significant issues. 

• Devise and execute a complex plan of work towards a goal. 

• Adapt to professional working practices in an overseas setting. 

• Contribute positively and effectively when working in a team. 

How the module will be delivered

Students take this module whilst undertaking a placement abroad. It consists primarily of project work supervised by the placement provider.   

The project activities undertaken during the placements are presented in a written report, and also a video presentation. 

Skills that will be practised and developed

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Graduate Attributes – Assessment:    

  

Coursework – Placement review 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Coursework – Video Presentation 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Coursework – Report 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

Goal 4. Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all 

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, and decent work for all  

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

How the module will be assessed

The module will be assessed via coursework including a written report, a video presentation of the project, and an essay reviewing the placement. 

 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  

 

You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the first available Examination period after the Examining Board. 

 

Students who are permitted by the Examining Board to be reassessed in this module, will need to resubmit each failed component of the module (report, video presentation and/or placement review) during the next available Examination Period. 

Assessment Breakdown

Type % Title Duration(hrs)
Report 65 Report N/A
Presentation 25 Video Presentation N/A
Written Assessment 10 Placement Review N/A

Syllabus content

The placement experience will be undertaken in the university host approved by the placement scheme coordinator.  

The main feature will be a substantial project on a chemical sciences topic determined by the host.  

This will be carried out on a time scale appropriate for the particular placement but is expected to take about 900 hours of your time, including all literature work, project work, preparation of presentation and written report.  

It is expected that all of the nominal 900 hours will be spent on the project at the host.  

The main report will be supplemented by a short reflective placement review, describing the particular environment of the placement - aspects of cultural differences between the host university and the UK, skills development during the placement and adapting to working overseas. 

Regular contact will be maintained throughout, primarily through the personal tutor, with involvement by the placement coordinator, as necessary. 


CH9351: Placement Experience in Industry (MChem)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH9351
External Subject Code 101043
Number of Credits 90
Level L6
Language of Delivery English
Module Leader Dr Sankar Meenakshisundaram
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module is taken by MChem students on placement in industry.  

 

The main feature will be a substantial project on a topic determined by the placement provider. Placements will be approved by the School placement coordinator.  

 

This will be carried out on a timescale appropriate for the particular placement, with duration no less than 9 months and up to 12 months.  

 

The main report will be supplemented by a short placement review, describing the particular environment of the placement and a reflective commentary on skills development. 

On completion of the module a student should be able to

Describe and present the objectives, methods and outcomes of a project in oral and written form. 

• Retrieve and communicate data, findings, and procedures from a variety of sources. 

• Analyse a topic to give a discussion and critical assessment of the significant issues. 

• Devise and execute a complex plan of work towards a goal. 

• Adapt to professional working practices in an industrial setting. 

• Contribute positively and effectively when working in a team. 

How the module will be delivered

 

Students take this module whilst undertaking a placement in industry. It consists primarily of project work supervised by the placement provider and other tasks aligned to the business of the placement provider.   

The project activities undertaken on placement are presented in a written report, and also a video presentation. 

Skills that will be practised and developed

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Graduate Attributes – Assessment:    

  

Coursework – Placement review 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Coursework – Video Presentation  

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Coursework – Report 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

Goal 4. Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all 

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, and decent work for all  

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

How the module will be assessed

 

The module will be assessed via coursework including a written report, a video presentation of the project, and an essay reviewing the placement. 

 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  

 

You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the first available Examination period after the Examining Board. 

 

Students who are permitted by the Examining Board to be reassessed in this module, will need to resubmit each failed component of the module (report, video presentation and/or placement review) during the next available Examination Period. 

 

 

Assessment Breakdown

Type % Title Duration(hrs)
Report 65 Report N/A
Presentation 25 Video Presentation N/A
Written Assessment 10 Placement Review N/A

Syllabus content

The placement experience will be undertaken in an industrial host approved by the placement scheme coordinator.  

The main feature will be a substantial original project on a chemical sciences topic determined by the host. Project work may consist of several smaller work packages, but it is expected that these will provide scope for independent thought and decision making. 

This will be carried out on a time scale appropriate for the particular placement but is expected to take about 900 hours of your time, including all literature work, project work, preparation of presentation and written report. It is recognised that the nature of the host’s business may require you to spend time on routine activities relating to the business but outside the scope of the project, but these activities should not form the bulk of your duties. 

The main report will be supplemented by a short reflective placement review, describing the particular environment of the placement, the business aspects of the placement host, and how your skills have been applied and developed during the placement. 

Regular contact will be maintained throughout, primarily through the personal tutor, with involvement by the placement coordinator, as necessary. 


CH2401: Project

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH2401
External Subject Code 100417
Number of Credits 40
Level L7
Language of Delivery English
Module Leader Dr Athanasia Dervisi
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module is only available to exchange students.  A student taking this module will gain experience of original research, and have the opportunity to put into safe practice the previous training in techniques and methods of chemistry, and to produce a dissertation to a professional standard including review of appropriate literature.

On completion of the module a student should be able to

  1. describe in detail the chemistry of the chosen topic, including background information from the literature and new results;
  2. explain the chemistry underlying the chosen project.

How the module will be delivered

The student will undertake a project in a research laboratory under the supervision of a member of academic staff.  The results will be presented in a written report.

Skills that will be practised and developed

Intellectual skills

On completion of the module the student will be able to show a detailed and advanced mastery of a specific topic at the research frontier level.

Chemistry –specific skills

On completion of the module the student will be able to:

  1. plan and carry out an original investigation in a topic from any part of practical or theoretical chemistry;
  2. select source literature and place it within the context of the project, with critical assessment of preceding work;
  3. record all working notes in an appropriate manner, with reference to risk and hazard where applicable;
  4. plan and compose a detailed report in standard format on all aspects of the project;

 

Transferable skills

On completion of the module the student will be able to present and defend a case following detailed study.

How the module will be assessed

The module will be assessed on the basis of performance in the laboratory, a written report.

Assessment Breakdown

Type % Title Duration(hrs)
Project 100 Report N/A

Syllabus content

This module consists of one supervised research project spread over a single semester, in any suitable area of chemistry. The work will include new studies, a literature survey, and preparation of a project report.

Topics will normally involve practical laboratory work, but projects with a large theoretical component are also possible, in appropriate areas.


CH2401: Project

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH2401
External Subject Code 100417
Number of Credits 40
Level L7
Language of Delivery English
Module Leader Dr Athanasia Dervisi
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module is only available to exchange students.  A student taking this module will gain experience of original research, and have the opportunity to put into safe practice the previous training in techniques and methods of chemistry, and to produce a dissertation to a professional standard including review of appropriate literature.

On completion of the module a student should be able to

  1. describe in detail the chemistry of the chosen topic, including background information from the literature and new results;
  2. explain the chemistry underlying the chosen project.

How the module will be delivered

The student will undertake a project in a research laboratory under the supervision of a member of academic staff.  The results will be presented in a written report.

Skills that will be practised and developed

Intellectual skills

On completion of the module the student will be able to show a detailed and advanced mastery of a specific topic at the research frontier level.

Chemistry –specific skills

On completion of the module the student will be able to:

  1. plan and carry out an original investigation in a topic from any part of practical or theoretical chemistry;
  2. select source literature and place it within the context of the project, with critical assessment of preceding work;
  3. record all working notes in an appropriate manner, with reference to risk and hazard where applicable;
  4. plan and compose a detailed report in standard format on all aspects of the project;

 

Transferable skills

On completion of the module the student will be able to present and defend a case following detailed study.

How the module will be assessed

The module will be assessed on the basis of performance in the laboratory, a written report.

Assessment Breakdown

Type % Title Duration(hrs)
Project 100 Report N/A

Syllabus content

This module consists of one supervised research project spread over a single semester, in any suitable area of chemistry. The work will include new studies, a literature survey, and preparation of a project report.

Topics will normally involve practical laboratory work, but projects with a large theoretical component are also possible, in appropriate areas.


CH3401: Project

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH3401
External Subject Code 100417
Number of Credits 60
Level L7
Language of Delivery English
Module Leader Professor James Platts
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module consists of a supervised research project spread over two semesters, selected from a portfolio prepared by members of staff from their own research interests. The work will include new studies, a literature survey, and preparation of a project report which will be examined orally. 

On completion of the module a student should be able to

Explain the chemistry underlying the chosen project to a specialist or lay audience. 

Carry out experiments and/or simulations as directed by an academic supervisor. 

Devise experiments and/or simulations, carry them out and analyse their outcome either in-lab or in-silico. 

Work safely and efficiently on research level tasks. 

Disseminate results in both report and oral format.  

Research the literature to further research aims and design experimental protocols. 

Describe in detail the chemistry of the chosen topic, including background information from the literature and new results. 

Work with independence whenever possible.  

How the module will be delivered

Independent investigation, both in research laboratories and library, supervised by a member of academic staff or their nominee from research group.  

Skills that will be practised and developed

Chemistry-specific skills 

On completion of the module the student will be able to: 

1. Plan and carry out an original investigation in a topic from any part of practical or theoretical chemistry; 

2. Select source literature and place it within the context of the project, with critical assessment of preceding work; 

3. Record working notes in an appropriate manner, with reference to risk and hazard where applicable; 

4. Plan and compose a detailed report in standard format on all aspects of the project; 

5. Present a lecture about the work and answer questions; 

6. Defend the report in oral examination. 

Transferable skills 

On completion of the module the student will be able to present and defend a case following detailed study. 

How the module will be assessed

The module will be assessed on the basis of performance in the laboratory, a written report, an oral presentation and an oral (viva voce) examination.

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

Reassessment will consist of a further attempt at report, oral presentation and/or oral examination, depending on those parts that contributed to failure on original submission. It will not normally be possible to extend or repeat experimental/theoretical work as part of reassessment. 

Assessment Breakdown

Type % Title Duration(hrs)
Dissertation 40 Written Report N/A
Practical-Based Assessment 20 Intellectual and/or Practical Contribution N/A
Presentation 20 Oral Presentation N/A
Oral/Aural Assessment 20 Oral Examination N/A

Syllabus content

This module consists of one supervised research project spread over two semesters, in any suitable area of chemistry. The work will include new studies, a literature survey, and preparation of a project report which will be examined orally. Topics will normally involve practical laboratory work, but projects with a large theoretical component are also possible, in appropriate areas. 


CH3402: Frontiers in Ligand Design and Coordination Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH3402
External Subject Code 101043
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Benjamin Ward
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module will focus on the structure, influence, and design of ligands in the development of functional metal complexes and main-group compounds.  

Three areas will be covered, representing a cross section of pertinent problems in this area, these will be:

a) the chemistry and catalytic applications of d0 metal complexes;  

b) the study of N-heterocyclic carbene complexes and their catalytic chemistry;  

c) the stoichiometric and catalytic reactions of frustrated Lewis pairs.  

The module will cover the synthesis of ligand precursors, coordination chemistry, including in cases where there is no electronic preference to coordination geometry, and homogeneous catalysis.  

Attention will be given to the analysis of structure-activity relationships and the interpretation of catalytic data in terms of reaction mechanisms.

On completion of the module a student should be able to

  • Formulate a catalytic reaction mechanism within unfamiliar operating parameters (e.g. catalyst and/or substrate structure). 

  • Critically evaluate catalytic reaction data in terms of the likely reaction mechanism, substrate structure, and catalyst design; assess structure-reactivity effects of ligands and formulate reactivity patterns. 

  • Design an appropriate synthetic strategy for ligands and complexes within provided constraints. 

  • Choose appropriate analytical techniques to characterise chemical species and assess analytical data in terms of chemical structure. 

How the module will be delivered

The module will be delivered in 10 2-hour lectures and three 1-hour tutorials.

The module consists of three distinct blocks, each covering a different aspect of advanced ligand design and coordination chemistry. 

The three blocks will mirror the three sections described above: 

(a) catalysts based on d0 metal complexes;  

(b) N-heterocyclic carbene complexes in catalysis; 

(c) the catalytic chemistry of frustrated Lewis pairs. 

Each block will be followed by a tutorial in which problem-solving and analytical skills are practised. 

Skills that will be practised and developed

Chemistry-Specific Skills: 

Students will already know how to construct a catalytic mechanism for simple catalysts and substrates (level 6); in this module students will learn how to analyse complex datasets and to formulate an explanation for trends and observations of chemical reactivity patterns, thereby developing a level of understanding closer to situations expected in graduate-level employment.  

Students will refine their problem-solving skills in situations that require them to synthesise a coherent argument or explanation using knowledge/data from a number of different sources.

Employability skills:     

This module is delivered and aligns with the following University Graduate Attributes: 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

Graduate Attributes – Assessment:   

 Coursework                        20% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 Exam                                  80% 

  •  Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.   

Sustainable Development Goals:    

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

Goal 6. Ensure availability and sustainable management of water and sanitation for all.

Goal 12. Ensure sustainable consumption and production patterns. 

Goal 13. Take urgent action to combat climate change and its impacts.  

How the module will be assessed

Formative assessment will be provided in the three tutorial sessions following each of the three theory blocks. These tutorials will be interactive and will develop the problem-solving skills required to apply the core lecture material to unfamiliar situations.

Summative assessment will take the form of coursework (30%) and written examination (70%). Coursework will consist of a single piece of work of three 10-mark questions; each question will be problem-based and will require students to apply concepts of ligand design to synthesise catalytic mechanisms within unfamiliar operating parameters. This will allow students to meet learning objectives 1 and 2.

The examination will consist of four 20-mark questions; students must answer any three. Questions will probe students’ ability to interpret data and to construct mechanistic arguments based on provided data, thus allowing students to meet learning objectives 3-4.

Marking criteria 

50-60 Satisfactory appreciation of the key concepts of catalyst design and their structural influence on catalytic reactions. Work in this category will demonstrate the ability to design catalytic cycles to an unfamiliar substrate and/or catalyst that are similar (but not identical) to those given in lecture material. There will also be a demonstrable ability to construct a ligand and/or catalyst synthesis from the molecular types illustrated in the lecture material.

60-70 Good grasp of most concepts relating to catalyst performance in relation to catalyst and substrate structure. Will demonstrate the ability to relate material from across all areas of the course to synthesise a rational explanation for catalyst performance and chemical reactivity. Will be able to propose a more advanced chemical synthesis pathway and an appreciation for how analytical techniques can aid the understanding of catalyst performance.

70-100 Excellent demonstration of catalyst design and structural influence on catalytic reactions. An outstanding ability to make connections between different areas of knowledge to aid a thorough interpretation of unfamiliar data, providing a rigorous spectroscopic/mechanistic/structural analysis. The ability to demonstrate appropriate weighting in different parameters that can affect chemical reactivity as applied to an unfamiliar situation.

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session.

The resit examination will adopt the same format as the main examination but will contain questions that allow students to demonstrate learning objectives 1-4. 

 

 

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Written Assignments N/A
Exam - Autumn Semester 80 Frontiers in Ligand Design and Coordination Chemistry 2

Syllabus content

The applications of ligand design and coordination chemistry to a range of areas, including catalysis and p-block chemistry, with an emphasis on the ability of controlling the properties and reactivity of metal complexes by ligand design.

The properties of d0metals in polymerisation catalysis 

A detailed mechanistic understanding of the properties and reactivity of d0 metal alkyl and alkyl cations will be discussed.  These complexes have most widely studied in the context of alkene polymerisation, and this type of reactivity will be used to exemplify the reactivity of d0 complexes.  The level of detail moves on from that covered in level 6, encompassing the catalyst structures required for the production of stereospecific polymers and the influence of agostic interactions to facilitate migratory insertion reactions.  This theme will be expanded to introduce the polymerisation of cyclic esters, commonly used as biodegradable polymers.

Heterofunctionalisation catalysis 

The role of d0metal complexes as catalysts for a range of organic transformations will be discussed, with particular focus on hydroamination, hydrogenation, hydrosilylation, and hydrophosphination.  A particular focus will be given to looking at the mechanisms of these reactions, for which there are less reaction steps possible (e.g. oxidative addition is precluded). This theme will be expanded to cover alkaline earth metals in catalysis, including their environmental benefits, their scope, and their limitations.

N-heterocyclic carbenes 

Introduction to N-Heterocyclic Carbenes (NHC) as ligands and their complexes with transition metals, providing knowledge of the routes to their synthesis as well as on their structure, reactivity, and electronic/steric properties. The scope and advantages of metal NHC compounds and their application in catalysis.

p-Block organometallics 

Introduction to p-block organometallics, including structure and reactivity trends will be provided. This will lead to a detailed discussion of frustrated Lewis pairs (FLPs), and their role in catalysis. 


CH3403: Bio-imaging Applications of Coordination Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH3403
External Subject Code 100948
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Professor Simon Pope
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

The module consists of three main topics associated with the application of inorganic coordination compounds to biological and biomedical imaging: luminescence, magnetic resonance and radio imaging will be covered. 

The module will provide a technical background to each of the imaging modalities and then focus upon the use and application of metal coordination compounds in each discipline, including modern commercial/clinical settings. 

Aspects of synthesis and molecular design will be described, and the ability to rationalise the relationship between complex structure and function (including the biological context) will be a fundamental focus. 

On completion of the module a student should be able to

  • Describe the fundamental concepts and principles that underpin fluorescence imaging, magnetic resonance imaging and radio imaging techniques. 

  • Discuss the physical concepts that drive the ligand design and choice of metal ion for a given imaging application 

  • Understand the synthetic chemistry pathways to selected ligands and complexes 

  • Demonstrate a critical awareness of the strategies for metal complex biocompatibility and stability in vitro and in vivo 

How the module will be delivered

This module will be delivered in ten two-hour lectures, supplemented by three 1-hour class tutorials. Three staff will teach, each delivering the three subtopics.  

A summative workshop (30%) will require a detailed critical analysis of a literature work based on a particular class of imaging agent. 

Skills that will be practised and developed

Academic Skills:

  • Understanding what kind of information is provided by different imaging techniques 

  • Interpret complex scientific information and relate to properties of different classes of imaging agent 

  • Develop effective skills focussed upon reviewing primary literature and extracting relevant information 

Chemistry-Specific Skills:

  • Understand the underpinning fundamental principles of optical, MRI and radio imaging 

  • Be able to interpret relate to molecular design of imaging agents to target applications 

  • Be able to analyse physical data and apply in problem solving  

Employability Skills:

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

Graduate Attributes – Assessment:     

 Written Assessment                      20% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 Exam                                             80% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.

Sustainable Development Goals:     

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

Goal 3. Ensure healthy lives and promote well-being for all at all ages         

How the module will be assessed

Summative assessment: workshop is a take-home assessment that requires engagement and analysis of the primary literature on a responsive bimodal imaging agent – it is a word count limited written report. This will assess a student’s ability to use electronic data bases and locate relevant information and critically review the primary literature. This will assess a student’s knowledge of molecular design and a deep understanding of the physical parameters that describe physical properties and dictate the biological application.  

A written exam (2 hour, 70%) will test the student’s ability to demonstrate their deep knowledge and understanding of the syllabus content, and their ability to apply the techniques/concepts covered to unseen problems.  

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session. 

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Written Assignments N/A
Exam - Autumn Semester 80 Bio-imaging Applications of Coordination Chemistry 2

Syllabus content

Optical imaging using Luminescence 

Background on confocal fluorescence microscopy for cellular imaging 

Background on photo physics – Stokes shift, Jablonski diagrams, time resolved vs steady state measurements, quenching pathways, types of emission, tuning emission through ligand design.

Types of TM-based luminophore including descriptions of ligand design, synthesis, photo physics and applications to imaging and biocompatibility

                  - d6 Ru(II), Re(I), Ir(III) complexes

Discussion of variants for organelle targeting and structure/function relationships.

Types of lanthanide(III)-based luminophore including descriptions of ligand design, synthesis, photo physics and applications to imaging and biocompatibility

                  - visible emission using Eu(III) and Tb(III) 

                  - near-IR emission using Nd(III) and Yb(III)

Magnetic Resonance Imaging and Contrast Agents

Background on magnetic resonance imaging. The history and the basic principles of the experiment. 

Background on the fundamental properties and design of T1 and T2 contrast agents. 

Types of complexes used for T1 contrast- lanthanide, transition metal and organic molecules. 

Types of complexes used for T2 contrast- lanthanides and transition metal clusters. 

Using CEST and PARACEST for imaging. 

Assessing new contrast agents –solubility, stability and the NMRD. 

Dual mode imaging and the theranostic approach.

Gamma Radio-Imaging via SPECT and PET 

Background to gamma imaging – physical basis of the techniques, data capture and imaging 
Single Photon Emission Tomography (SPECT) 
Positron Emission Tomography (PET) - 
general properties of PET/SPECT isotopes, half-lives, imaging resolution, biological matching 

Background to functional imaging vs. structural imaging – 
organ perfusion imaging, inflammation imaging, bone imaging (SPECT) 
biologically active PET probes (FDG, F-DOPA, etc.) 

Ligand design for SPECT and PET isotopes and metal complexes – 
Tc complexes for SPECT 
Ga, Cu, Zr, Y complexes in PET 

 

Essentail Reading and Resource List:

References to the primary literature will be given throughout and students will be expected to utilise WoK to access supporting information to the lecture notes. 

Background reading and Resource List:

Principles of Fluorescence Microscopy, J.R. Lakowicz 

Handbook of Radiopharmaceuticals, Eds Welch, Redvanly (Wiley) 

References to the primary literature will be given throughout and students will be expected to utilise WoK to access supporting information to the lecture notes


CH3404: Asymmetric Synthesis of Pharmaceuticals and Natural Products

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH3404
External Subject Code 100422
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Professor Thomas Wirth
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module consists of a range of examples exposing the students to sophisticated methods in stereoselective synthesis. 

Building on required previous modules such as CH4303, advanced methods for stereo control in total synthesis, preparation of enantiomerically pure drug molecules, development of stereoselective reactions as well as the introduction of various enabling technologies will be the main focus of this module. 

Throughout, the ability to extract stereo chemically relevant information from complex syntheses will be a major focus. 

On completion of the module a student should be able to

  • Appreciate the range of synthetic methods available to prepare enantiomerically pure molecules.   

  • Know the strategies and reagents required to generate and implement new stereochemical elements within target-oriented syntheses.   

  • Identify key problems in both small-scale academic synthesis and large-scale industrial synthesis of stereo chemically pure compounds.   

  • Identify different reaction technology equipment and summarise the key criteria to consider before using it.   

  • Understand the principles and strategies of stereoselective alkene functionalization.   

  • Understand main principles in the use of enabling technologies and related industrial issues together with application to target molecules.   

  • Recognize where organocatalysis can be applied in synthesis and which strategies in this area are available.   

  • Explain when alternative tools and techniques may offer significant benefit to a desired reaction outcome.  

How the module will be delivered

10 two-hour lectures, supplemented by 2 1-hour class tutorials.

Skills that will be practised and developed

Chemistry-Specific Skills:

  • Ability to analyse stereochemical problems and provide synthetic meaningful solutions.   

  • Assess and solve problems in asymmetric synthesis together with their theoretical background and any strengths or weaknesses associated with them.   

  • Identification of chemical problems which can be solved by involving enabling technologies.  

Employability skills:       

This module is delivered and aligns with the following University Graduate Attributes:    

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

Graduate Attributes – Assessment:     

Workshop                        20% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

Exam                               80% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Sustainable Development Goals:        

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture

Goal 3. Ensure healthy lives and promote well-being for all at all ages

Goal 12. Ensure sustainable consumption and production patterns

 

How the module will be assessed

Written exam and Workshop.  

The workshop and the written exam will focus on different topics due to the timing of these events. They will enable the students to demonstrate that they have achieved the learning outcomes.   

Marking criteria will involve the validity of the provided answers and the ability of the student to handle unknown material.   

Further details (dates) are found in the assessment map.   

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:   

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session.  

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Written Workshop N/A
Exam - Autumn Semester 80 Asymmetric Synthesis of Pharmaceuticals and Natural Products 2

Syllabus content

Alkene Functionalisations   

Introduction to advanced asymmetric synthesis. Stereoselective functionalisations of double bonds: Briefly revising Sharpless AE and ADH, Jacobsen (year 3), then introduction of other electrophilic reagents including selenium- and iodine-based compounds.  Applications in total synthesis and the synthesis of bioactive compounds will be discussed.  

Enabling Tools for Organic Synthesis   

As synthesis moves into the modern era so too does the way in which chemists can conduct chemistry. This part of the course introduces the technical considerations needed for using existing and futuristic synthesis tools such as microwave reactors, photochemical reactors, electrochemistry, and continuous flow chemistry. Important factors are being considered when conducting reactions using these methods, there will also be a strong focus on the types of synthetic chemistry suited to these modes.  

Organocatalysis   

Organocatalysis is defined as the use of a sub-stoichiometric amount of an organic molecule to accelerate the rate of a chemical reaction. This part will serve as an introduction to the diverse and exciting field of organocatalysis and will specifically cover: a historical perspective; benefits and limitations; catalyst synthesis; covalent and non-covalent organocatalytic activation modes; selectivity (regio-, diastereo- and enantiocontrol); applications within industry; applications towards the synthesis of biologically active compounds.  


CH3406: Molecular Modelling

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH3406
External Subject Code 101050
Number of Credits 10
Level L7
Language of Delivery English
Module Leader DR Alberto Roldan Martinez
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module exposes students to the range of computational methods that can be applied to diverse chemical problems, from the structure and property of molecules to chemical thermodynamics, kinetics, and reactivity.  

Methods for describing molecules, ranging from quantum chemical and molecular orbital methods for relatively small molecules to atomistic simulation of larger, more complex systems will be discussed. 

Throughout, the ability to extract chemically relevant properties from molecular modelling experiments will be a major focus.  

On completion of the module a student should be able to

  • Explain the fundamentals of theories underpinning the range of modelling methods available to tackle chemical problems.    

  • Design appropriate feasible methodology for the modelling of a given chemical problem, drawing on knowledge of particular methods, errors, and computational costs.   

  • Identify the key results obtained from calculations and interpret these with regard to the physics/chemistry of the problem.    

  • Critically evaluate computation schemes presented in primary chemical literature.   

  • Analyse and evaluate the errors in modelling schemes.   

How the module will be delivered

A blend of on-line learning activities with face-to-face learning support and feedback.  

20 x 1 h lectures, 4 x 1-hour tutorials. Lectures will deliver the core course content, addressing all learning outcomes. 

Formative tutorials will selectively address learning outcomes, with emphasis on problem solving and forging links between topics.  

The module does not contain a practical component, or instruction in the use of particular software elements, but instead develops understanding of the underlying theoretical concepts through discussion of examples of application to chemical problems. 

Skills that will be practised and developed

Academic Skills:

  • You will analyse a published research paper, extracting the key scientific outcomes, research rationale, and techniques, helping you develop both critical thinking and written communication skills.  

Chemistry-Specific Skills 

  • You will develop the necessary skills to identify the appropriate theoretical and computational methods to predict and interpret the properties of molecules, liquids, and surface processes, developing independent and critical thinking skills.    

Employability skills:     

This module is delivered and aligns with the following University Graduate Attributes:   

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future 

Graduate Attributes – Assessment:   

In-Course Assignment             20% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future 

 

Exam                                         80% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future 

  

Sustainable Development Goals:      

This module does not align with any of the Sustainable Development Goals, but its topics do underpin all.  

How the module will be assessed

The module is assessed through two components: a 2-hour exam in the January exam period (80%), and a take-home assignment during the teaching period (30%).   

The take-home assignment gives opportunity for students to demonstrate understanding of concepts and methods presented, and their ability to analyse the rationale and outcomes of a piece of primary literature. Feedback is provided.   

The examination consists of a variety of questions which test a candidate’s knowledge and understanding of concepts, and their ability to deploy those concepts on unseen problems.  The portfolio of question parts is constructed so that some parts can be answered with a basic level of knowledge and understanding, and other parts support the demonstration of deeper understanding and capability.  The overall balance of these aspects is designed such that candidates can demonstrate satisfaction of the learning outcomes at a basic level and receive the pass mark.   

A number of elements of formative course work are provided in addition, in order to give the opportunity to deepen understanding through application, with feedback through a combination of interactive tutorials and written comments.   

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:   

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.   

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session. 

 

 

 

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 In-course Assessment N/A
Exam - Autumn Semester 80 Molecular Modelling 2

Syllabus content

Schrödinger equation, Born-Oppenheimer approximation, potential energy surface. Topography of potential energy surfaces. Parameterised forms for bonded interactions and non-bonded interactions. Application to varied chemical systems.  

Correlated wavefunction and density-functional methods; electromagnetic properties; excited states; intermolecular interactions.   

Fundamentals of Molecular Dynamics; time propagation algorithms; periodic boundary conditions; radial distribution functions; thermodynamics of ensembles; examples of applications.  

Hartree-Fock and Density-Functional theories for periodic solids; molecular and dissociative adsorption; reactivity and principles of microkinetic modelling. 


CH3407: Advanced Materials

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH3407
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Jonathan Bartley
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

The module aims to develop an understanding of the synthesis, characterization, simulation, and applications of specific advanced materials in the modern chemical environment.  

The course will cover semiconductor materials; material surfaces and nanoparticles; colloidal systems in industry and healthcare; heterogeneous catalysis with nanoparticles and bulk catalysts; and the modelling, synthesis, and characterisation of these advanced materials.

On completion of the module a student should be able to

  • Systematically understand how different methods for synthesising and formulating advanced materials can impact on their performance in different applications.   

  • Evaluate and predict key properties of materials based on modelling and characterisation data.  

  • Analyse experimental/characterisation/modelling data for different advanced materials to probe the material properties and establish an understanding between structure, composition, and chemistry.  

  • Critically assess literature relating to advanced materials properties and applications.  

  • Relate computational and experimental information on catalytic systems to understand the relationship between structure and performance.  

How the module will be delivered

You will receive course content delivered primarily using face to face lectures. 

The course consists of 10 x 2-hour lectures during the Spring semester, with approximately 3 lectures a week for 3-4 weeks. 

Lectures may include some worked problems and informal formative questions to support principles introduced. These will help you to address the learning outcomes and provide opportunities to apply knowledge and develop understanding.  

 

The lecture schedule will follow the module map published prior to the start of the module. Lectures will be recorded and will be available following the live sessions. 

A combination of lecture slides and additional supporting notes will be available for you prior to the face-to-face lectures. 

Lecture material will be supported by four formative workshops that will focus on problem solving based on material from lectures and discussions around the course content. 

These formative workshops will provide you with guidance and support for the assessed coursework and examination.  

Skills that will be practised and developed

Skills developed through formal module learning outcomes and summative assessment include: 

Academic Skills:

  • Assessments require independent critical thinking to analyse problems and the ability to communicate complex information. 

  • In the summative workshop exercise you will analyse a research article, drawing out the key information and exercise critical judgement in evaluating sources of information. 

 

Chemistry-Specific Skills

  • You will develop chemistry specific skills, focussed on applying ideas from fundamental physical and inorganic chemistry and apply innovative thinking to understand how these can be applied to the use of advanced materials for different applications.  

  • You will develop intellectual curiosity and develop new understanding of how properties of materials can be controlled by tuning the synthesis procedure and how advanced characterisation methods can be used to help derive structure activity relationships.  

 

Employability skills:   

This module is delivered and aligns with the following University Graduate Attributes:  

  •  Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future 

 

 

Graduate Attributes – Assessment:    

  

 Coursework                      20% 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Listen to and take account of the views of others. 

  • Consider own personal and professional ethical, social, and environmental responsibilities. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 Exam                                80% 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Listen to and take account of the views of others. 

  • Consider own personal and professional ethical, social, and environmental responsibilities. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

  

Sustainable Development Goals:      

This module is delivered and aligns in working towards the following Sustainable Development Goals:  

Goal 6. Ensure availability and sustainable management of water and sanitation for all

Goal 7. Ensure access to affordable, reliable, sustainable, and modern energy for all

Goal 12. Ensure sustainable consumption and production patterns  

Goal 13. Take urgent action to combat climate change and its impacts        

Goal 14. Conserve and sustainably use the oceans, seas, and marine resources for sustainable development 

How the module will be assessed

Summative assessment will take the form of a written examination and a written piece of coursework.  

A two-hour closed book written exam will test your ability to demonstrate knowledge and understanding of the syllabus content, and your ability to apply the techniques and concepts covered to problems solving that are related to familiar and unseen examples.   

The summative coursework will allow you to demonstrate your ability to review and evaluate research from the literature through the preparation of a short-written report (2 pages). You will be able to choose between papers relating to colloids, nanoparticles and catalysis for the coursework and will need to identify how different characterization techniques can be used to gain understanding of materials. You will receive feedback on your work before the written exam.  

Your learning will also be supported by the formative workshops, and feedback provided either orally or in writing during and after the sessions. There will be a focus on supporting problem solving based on applying knowledge and understanding of materials properties for different applications.  

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Reassessment will follow the same format as the original component of the assessment. 

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Coursework Assignments N/A
Exam - Autumn Semester 80 Advanced Materials 2

Syllabus content

Colloidal systems: This part of the module will focus on structure-activity relationships in colloidal systems relevant to important applications in industry and healthcare, plus advanced methods used for their characterisation. Topics will include advanced characterisation techniques, structure activity relationships in surfactants, polymer solutions, polymer particle interactions, polymer surfactant interactions and supporting case studies. 

Synthesis of heterogeneous catalysts: This part of the module will focus on the synthesis of catalysts and supports. It will include case studies of different catalyst systems. Different synthesis methods will be introduced such as sol-gel, hard and soft templating, antisolvent precipitation to prepare bulk catalysts and supports. Methods of preparing supported catalysts will also be covered including impregnation, deposition-precipitation, and the use of pre-formed sols. 

Design advanced materials: This part of the module will focus on the fundamental properties of advanced materials. It will include review of the properties of semiconductors, and the impact of defects on applications, including light-emitting diodes, transistors, and ionic transport; the properties of extended surfaces on geometric, energetic and electronic properties; the properties of mono- and bimetallic nanoparticles; and explaining nanoparticle-support interactions and how these, as well as environment, can modify the structural and electronic properties and change the functionality of an advanced material.


CH3410: Advanced Magnetic Resonance Spectroscopy: Principles and Applications

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH3410
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Professor Damien Murphy
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

Magnetic resonance techniques, including NMR and EPR, are extremely powerful tools for investigating the structure and dynamics of molecules. 

This module offers the student the opportunity to study the underlying physical principles of NMR and EPR, primarily in the solid state, and the surrounding magnetic interactions that determine the appearance of the experimental spectra. 

Coverage of conventional principles in magnetic resonance, showing how the resonance frequency of a nucleus (or electron) is affected not only by the applied field but also by the electronic environment and surrounding nuclei, will be presented to the students.

A more advanced EPR technique, called ENDOR, where EPR and NMR transitions are simultaneously pumped and then monitored, will also be introduced in both liquid phase and solid phase conditions. 

Particular emphasis will be devoted to the analysis of NMR and EPR spectra in the solid state. 

The anisotropic interactions responsible for the broad and more complex spectral line shapes experienced in the solid state (compared to the isotropic profiles experienced in the liquid state) will be treated using a series of examples. 

The advanced methodology of angular selective ENDOR, used to analyse and extract structural information for paramagnetic species in frozen solution, will also be covered. 

On completion of the module a student should be able to

  • Understand the origin of the Zeeman interaction; 

  • Understand the importance of spin angular momentum and the spin magnetic moment in magnetic resonance spectroscopy; 

  • Describe the behaviour of nuclear and electron spins in an applied magnetic field; 

  • Understand the role of spin angular momentum as the foundation in NMR and EPR; 

  • Describe the importance of various magnetic interactions, such as spin-spin coupling, as a vital source of information;  

  • Understand the nature of anisotropic interactions in the solid state, and how they dictate the shape of the spectra; 

  • Understand how various magnetic interactions including electron Zeeman interactions, zero field splitting, hyperfine interactions, nuclear Zeeman interactions, and quadrupole interactions, can be extracted from the EPR spectrum; 

  • Know how dynamic, as well as structural information can be accessed in the solid state, and understand the importance of the timeframe of the NMR techniques in dynamic studies; 

  • Discuss the approaches taken to record NMR spectra in solid state; 

  • Describe how the ENDOR technique is performed and the role of saturation and relaxation phenomena in acquiring ENDOR signals with optimal amplitudes; 

  • Describe how the angular selective ENDOR methodology is applied to study paramagnetic systems in the solid state.

How the module will be delivered

A blend of on-line learning activities with face-to-face small group learning support and feedback.

The module will be delivered in 10 two-hour lectures, supplemented by 4 one-hour class tutorials. 

Skills that will be practised and developed

Chemistry-Specific Skills:

  • Link formal equations to observed NMR/EPR spectra; 

  • Interpret experimental observations in terms of the molecular and structural properties of the system; 

  • Select appropriate techniques for determination of structure in solution or solid state for a range of chemical situations; 

  • Assess the advantages/disadvantages of the different techniques for each particular purpose and chemical problem; 

  • Appreciate the steps involved in the analysis of modern magnetic resonance experiments; 

  • Understand how NMR/EPR may be used to study problems of general chemical interest; 

  • Use qualitative arguments to develop a theoretical description of magnetic resonance phenomena; 

  • Use quantitative measurements to verify or disprove theoretical models. 

Employability skills:      

This module is delivered and aligns with the following University Graduate Attributes: 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

Graduate Attributes – Assessment:    

 Written Assessment                 20% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 Exam                                        80% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

Sustainable Development Goals:    

This module does not align with any of the Sustainable Development Goals, but its applications will contribute towards all in part.

How the module will be assessed

The module will be assessed by a combination of coursework (20%) and written examination (80%). 

The single assessed piece of open-book coursework, containing questions based on both the NMR and EPR components of the module, will be delivered during the course.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Written Assignments N/A
Exam - Spring Semester 80 Advanced Magnetic Resonance Spectroscopy: Principles and Applications 2

Syllabus content

Foundations in Solid State NMR: This part of the course will provide an introduction to solid-state NMR spectroscopy, focusing initially on relevant theoretical background and experimental techniques. 

The discussion of background theory will highlight the significant differences between solid-state NMR and liquid-state NMR, focusing on the main anisotropic NMR interactions that are important in the solid state. 

The discussion of experimental strategies will then focus on the techniques for recording:  

a) broad-line solid-state NMR spectra (in which the anisotropic NMR interactions are studied), 

b) high-resolution solid-state NMR spectra (in which the aim is to record narrow-line spectra that resemble those recorded in liquid-state NMR). 

The course will then build upon these foundations by discussing the applications of solid-state NMR to investigate structural and dynamic properties of solids, highlighting the scope and limitations of different types of solid-state NMR technique. 

Several recent examples of the application of solid-state NMR to solve problems in solid-state and materials chemistry will be presented. 

Students attending the course will emerge with an appreciation of the types of problem that can be tackled successfully by solid-state NMR, and the particular NMR technique (or combination of techniques) is most suitable for investigating each type of problem.

Foundations of liquid and solid state EPR & ENDOR: The basic principles underlying the EPR technique will be covered, including coverage of the form of the spin Hamiltonian for systems in the solid state. This will initially be treated for the liquid phase, before considering the more complex case of the solid-state Anisotropy

Anisotropy of the g and A hyperfine tensors, and the role of symmetry as manifested in the g/A frame will then be presented to the students. 

The theory and applications of angular selective ENDOR, based on the angular dependency of the EPR spectra, will also be covered in the lectures. Examination of the profiles of EPR spectra in the solid state will then be covered. 

The lectures will then cover the theory of ENDOR, with particular emphasis on the saturation and relaxation pathways important in this technique. 

The role of angular selection as a means of determining structural information for paramagnetic centres in the solid state will then be given. 

Examples of systems with low g anisotropy (no hyperfine interaction) leading to powder ENDOR patterns, and subsequently axial g anisotropy and axial hyperfine, leading so ‘single crystal-like’ ENDOR patterns will then be investigated. 

The students will then appreciate the experimental approaches taken to obtain EPR and ENDOR spectra of paramagnetic centres in the solid state (primarily in frozen solution) and the general methodologies subsequently involved in the analysis and understanding of the experimental data. 

Numerous examples of how to interpret solid state EPR / ENDOR spectra will be covered during the course. 


CH3411: Catalytic Materials for Green Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH3411
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Professor David Willock
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module will cover the synthesis, characterisation and simulation of the catalytic materials that find applications in the Green Chemistry and energy sectors. 

The current trend in chemistry to reduce our dependence on fossil sources of carbon for chemicals and fuels is giving rise to a whole new set of challenges in catalysis. 

This module will discuss the environmental drivers for this shift. We will introduce the mechanistic pathways used to transform renewable resources into useful chemicals and identify the characteristics of the catalysts required. 

We will also survey the synthesis of catalysts and the applications for these materials. The module will emphasize how careful characterisation and simulation approaches can give a structure/activity level of understanding in heterogeneous catalysis that helps to design and optimise catalytic materials. 

You will develop critical analysis skills through study of literature case studies and quantitative approaches to defining how environmentally friendly a chemical process really is. 

On completion of the module a student should be able to

  • Discuss the environmental impact of chemistry and the use of catalysis to mitigate this impact. 

  • Appreciate the range of methodologies used in synthesising heterogeneous catalytic material including pre- and post-treatments applied to enhance/control catalytic activity.  

  • Describe the control of surface features, material phases and compositions that can be achieved using a variety of synthetic approaches.  

  • Interpret data from the characterisation methods used for heterogeneous catalytic materials and discuss the information which each method provides and reflect on the overall picture obtained by combining data from different approaches.  

  • Critically assess the mechanisms of sample catalytic target reactions in the Green Chemistry and energy sectors.  

  • Work with kinetic rate equations to interpret catalytic data giving conversion and selectivity as a function of time.  

  • Describe in situ measurements that are used to scope out elementary surface reactions during catalysis.  

  • Understand the main computational chemistry approaches used in the simulation of catalytic materials and catalysed reactions.  

  • Appreciate the use of computer simulation in establishing the electronic and geometric features of active sites on catalyst surfaces.  

  • Understand how computer simulation is applied to map out reaction energetics for key steps in heterogeneously catalysed reactions.  

  • Analyse example experimental and computational data from the literature on mechanisms of interest for Green Chemistry.  

  • Relate computational and experimental information on catalytic systems to understand the relationship between structure and performance. 

How the module will be delivered

The module content will be delivered via face-to-face activities lectures and discussion workshops.

Lecture material will be recorded and provided to support your independent learning. The material will also be supported by formative self- assessment tests introduced at regular points in the delivery schedule.  

The module will consist of 24 hours of lecture and 4 hours of discussion workshops and worked example problems.  

The week-by-week delivery schedule and timing of summative and formative tasks will be described in the module map.  

Skills that will be practised and developed

Academic Skills:

  • You will also have opportunities to apply these skills to analyse examples drawn from the scientific literature and be encouraged to collaborate with your peers in reviewing case studies.  

  • The formative and summative assessments will allow for collaborative working when researching literature data enabling discussion of ideas between peers. These discussions will focus on the scientific reasoning required to develop a process but will also be broader taking into account commercial aspects.   

 

Chemistry-Specific Skills: 

 

  • You will have the opportunity to develop your independent critical analysis and problem-solving skills, dealing with data from a variety of methods to come to a rounded understanding of catalyst structure, materials properties, and mode of operation in key catalytic processes.  

  • The module is centred in sustainable chemistry, and you will also acquire the vocabulary and analytical skills to exercise critical judgement regarding the contribution a particular catalytic process can make to improving the environment and reducing the impact of anthropogenic activity. 

 

Employability skills:     

This module is delivered and aligns with the following University Graduate Attributes:   

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Graduate Attributes – Assessment:    

  

 Written Assessment                20% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future 

 

 Exam                                       80%  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future 

 

 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:

Goal 7. Ensure access to affordable, reliable, sustainable, and modern energy for all 

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, and decent work for all 

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

Goal 12. Ensure sustainable consumption and production patterns  

Goal 13. Take urgent action to combat climate change and its impacts 

Goal 14. Conserve and sustainably use the oceans, seas, and marine resources for sustainable development 

Goal 15. Protect, restore, and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss.

How the module will be assessed

Formative assessments will include:  

A formative assignment will be used to give experience of drawing data from literature sources and use ideas from the module to interpret that data in terms of sustainability. Full engagement with the self-assessment exercise will prepare students for the summative assessment components of the module.  

Summative assessment will consist of a single piece of written work combining a number of literature sources. The marking scheme will assess the student’s understanding of the material in the literature sources and their ability to critically assess the way that a proposed process conforms to the concepts of Green Chemistry.   

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.  

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session.  

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Written Assignment N/A
Exam - Autumn Semester 80 Catalytic Materials for Green Chemistry 2

Syllabus content

The module will cover the synthesis of catalytic materials for Green Chemistry and energy sectors. 

The principals of Green Chemistry will be reviewed with current literature examples of industrial processes that have been superseded by more sustainable chemistry. 

The common metrics of atom economy and E-factor will be discussed in detail and students given the opportunity to evaluate these factors for example processes. 

The characterisation methods used to measure properties such as the solid phases present, the effective surface area of catalysts and spectroscopic inspection of working catalysts will be addressed. 

The main approaches to the computer simulation of catalytic materials will also be introduced, with examples that integrate with the theme of Green Chemistry drawn from the literature. 

Reaction schemes will be presented and discussed based on calculated potential energy surfaces and the insights these given into the catalytic processes they represent. 

The overall aim of the module is to demonstrate how materials characterisation and simulation can help to inform a mechanistic understanding of heterogeneous catalysis for key reactions in Green Chemistry.


CH3412: Supramolecular Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH3412
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Louis Luk
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

Supramolecular chemistry, which explores the concept of intermolecular dynamic interactions, plays a pivotal role in advancing organic chemistry, chemical biology, materials science, nanotechnology, and other areas where applied science is crucial. 

This module introduces students to the shift from classical molecular approaches, emphasising the understanding of concepts based on non-covalent bonding interactions among molecules and ions across various states and interfaces. 

This course will cover the fundamental principles of supramolecular chemistry, covering molecular cages, surface self-assembled networks and metal-organic frameworks. We will also explore their applications in chemical sensing and energy storage, highlighting the social and environmental implications of these supramolecular innovations in every life. 

Additionally, we will examine the supramolecular interactions involving nucleic acids and proteins, discussing their applications in drug delivery, biotherapeutic design, and chemical manufacturing. This exploration will further enhance students' understanding of the social and ethical aspects inherent in these scientific advances.

Beyond foundational knowledge, the course emphasises the development of independent thinking, creativity, and effective communication skills through collaborative projects. Students will be tasked with designing novel supramolecular systems of fundamental and/or applied interest, practicing their communication skills through group presentations. 

This approach not only reinforces their understanding but also nurtures creativity, encouraging them to design innovative molecular organizations with both fundamental and applied significance. 

On completion of the module a student should be able to

  • Understanding the critical role of supramolecular chemistry in applied science fields such as organic chemistry, chemical biology, materials science, and nanotechnology; 

  • Learn to describe the analytical methods used to study molecular interactions, a skill essential to a broad range of career paths; 

  • Discuss the application of supramolecular chemistry in industries and medicine, which will boost students' ethical and social awareness; 

  • Utilise fundamental concepts of supramolecular chemistry to develop logical solutions to novel problems, promoting innovative and reflective thinking; 

  • Retrieve, interpret and communicate data, findings and procedures relating to supramolecular chemistry from journals and databases. 

How the module will be delivered

The module will be delivered primarily using lectures (22 hours) where the principles of supramolecular chemistry will be introduced including case studies from the literature. In addition, lectures will include worked problems and informal ad hoc formative activities. 

Workshops (one formative, one summative) will be used to enhance and assess problem-solving and literature-searching skills. 

Skills that will be practised and developed

Chemistry-Specific Skills:

  • Students in this course will develop employable attributes applicable to a broad spectrum of career paths. 

  • They will gain a deep understanding of supramolecular chemistry and be familiarised with crucial data analysis skills essential in diverse job prospects.  

 

Employability skills:     

This module is delivered and aligns with the following University Graduate Attributes:  

   

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

Graduate Attributes – Assessment:    

  

 Oral Presentation                     20% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 Exam                                        80% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:  

 

Goal 3. Ensure healthy lives and promote well-being for all at all ages  

Goal 4. Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all ages 

Goal 6. Ensure availability and sustainable management of water and sanitation for all  

Goal 7. Ensure access to affordable, reliable, sustainable, and modern energy for all  

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, and decent work for all  

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

Goal 12. Ensure sustainable consumption and production patterns  

Goal 13. Take urgent action to combat climate change and its impacts  

Goal 14. Conserve and sustainably use the oceans, seas, and marine resources for sustainable development

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development Goals 

How the module will be assessed

Formative assessment: The first two workshops will be assessed formatively, and feedback provided either orally or in written form. This will give students an opportunity to revise the module content and to apply it to deduce and propose solution for supramolecular chemistry-based questions. 

 

Summative assessment: A summatively assessed workshop in the form of an oral presentation will allow the student to demonstrate their ability to use electronic resources to locate relevant information in the literature to provide a plausible proposal for a contemporary research topic. 

 

A written exam (2 hours) will test the ability to predict intermolecular interactions as well as propose and interpret experiments in supramolecular chemistry. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment are only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.

The reassessment will be by an examination during the resit examination period. 

Assessment Breakdown

Type % Title Duration(hrs)
Presentation 20 Oral Presentation N/A
Exam - Spring Semester 80 Supramolecular Chemistry 2

Syllabus content

  • Basic concepts in self-assembly and self-organization, including a systems chemistry approach, thermodynamics, and kinetics of host-guest processes along with the main characterization techniques;  

  • Complexation of neutral molecules in aqueous solution and their technological applications - sensors and drug delivery; Template effects & molecular self-assembly approach towards nanostructures in solutions (including molecular cages and inorganic nanotubes), on surfaces (2D networks and topology considerations);  

  • Non-covalent interactions involving aromatic rings; hydrogen-, halogen- and chalcogen-bonding interactions;  

  • Dynamic covalent bonds & supramolecular polymers;  

  • Experimental techniques and methods used to understand both nanoscale and ultrafast chemistry critical to many supramolecular processes and materials;  

  • Molecular machines, from catenanes and rotaxanes to more complex multi-station multi-stimuli responsive supramolecular systems;  

  • Basic concepts of molecular recognition in biology, including cell architecture, biomolecular interactions, structure of essential building units, lipids, DNA/RNA, protein, sugar; natural Ion channels, including peptide-based ion change, cation/anion complexation, cross-membrane ion channel;  

  • Supramolecular chemistry in biotechnological applications (e.g. designer enzyme, antibody drug conjugate, DNA-templated synthesis)  


CH3451: Prosiect

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH3451
External Subject Code 100417
Number of Credits 60
Level L7
Language of Delivery Welsh
Module Leader Dr Heulyn Jones
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

Mae’r modiwl hon yn cynnwys prosiect ymchwil wedi’i oruchwylio sydd yn cael ei gwblhau dros ddau semester, ac yn cael eu dewis o bortffolio ymchwil aelodau staff yr adran. Bydd y gwaith yn cwynnwys astudiaethau newydd, adolygiad o’r llenyddiaeth gyfredol ac adroddiad o’r prosiect ymchwil bydd yn cael ei arholi ar lafar. Bydd y goruchwylio, adroddiadau a’r arholi yn cael eu gwneud yn y Gymraeg.

On completion of the module a student should be able to

Gwybod (dyma bethau bydd rhaid i’r myfyrwyr wybod i basio’r modiwl)

  • Esbonio’r cemeg sydd wrth wraidd y prosiect a ddewisiwyd
  • Cwblhau arbrofion dan oruchwyliaeth y goruchwylydd academaidd.

Gwneud (bydd perfformiad yn y maes hyn yn galluogi myfyrwyr i ennill marc uwch na’r angen ar gyfer pasio’r modiwl)

  • Dyfeisio arbrofion, eu cwblhau a’u dadansoddi.
  • Cyflwyno’r canlyniadau mewn adroddiad ysgrifenedig ac ar lafar. 

Arweithio (bydd perfformiad yn y maes yma yn galluogi myfyrwyr i ennill marc uwch na’r angen ar gyfer pasio’r modiwl)

  • Ymchilio i’r llenyddiaeth gwyddonol i ymestyn nodau ymchil ac i ddarlunio protocolau arbrofol.
  • Disgrifio’n fanwl cemeg y pwnc a ddewisiwyd, gan gynnwys gwybodaeth cefndirol o’r llenyddiaeth wyddonol a chanlyniadau o’r newydd.
  • Gweithio’n annibynnol lle bynnag posib.

How the module will be delivered

396 (18 awr yr wythnos dros 22 wythnos) o oriau wedi’u hamserlenni i ymchwiliad annibynnol dan oruchwyliaeth aelod o staff academaidd.

Skills that will be practised and developed

Sgiliau deallusol

Ar gwblhad y modiwl, bydd y myfyriwr yn gallu dangos deallusrwydd manwl a dwys o’r pwnc penodol bydd ar ymyl y ffin lefel ymchwil.

Sgiliau cemegol  

Ar gwblhad y modiwl, bydd y myfyriwr yn gallu:

  1. Cynllunio a chwblhau ymchwiliad gwreiddiol o’r pwnc, boed yn gemeg ymarferol neu ddamcaniaethol;
  2. Chwilio a dewis o’r llenyddiaeth gwyddonol, ei drafod yn gritigol yng nghyswllt y prosiect gan asesu’n critigol y gwaith blaenorol yn y maes;
  3. Nodi’r canlyniadau mewn modd addas, gan gyfeirio tugat at risg a pherygl lle’n briodol;
  4. Cynllunio a chreu adroddiad manwl mewn ffurf addas ar bob agwedd o’r prosiect;
  5. Cyflwyno darlith ar yr ymchwil gan gynnwys ateb cwestiynau a ofynnir;
  6. Amddiffyn yr adroddiad mewn arholiad ar lafar.

Sgiliau trosglwyddadwy 

Ar gwblhad y modiwl, bydd y myfyriwr yn gallu cyflwyno ac amddiffyn yr ymchwil yn dilyn ymchwiliad manwl.

How the module will be assessed

Bydd y modiwl yn cael asesu ar sail berfformiad yn y labordy, yr adroddiad ysgrifenedig a’r cyflwyniad ar lafar (viva voce).

Assessment Breakdown

Type % Title Duration(hrs)
Dissertation 40 Adroddiad ysgrifenedig N/A
Practical-Based Assessment 20 Cyfraniad deallusol ac ymarferol N/A
Presentation 20 Cyflwyniad ar lafar N/A
Oral/Aural Assessment 20 Arholiad ar lafar N/A

Syllabus content

Mae’r modiwl yma’n cynnwys un prosiect ymchwil wedi’i oruchwylio dros ystod ddau semester mewn unrhyw faes addas o fewn cemeg (lle bo’n bosib). Bydd y gwaith yn cynnwys astudiaethau newydd, adolygiad o’r llenyddiaeth wyddonol a chwblhad adroddiad o’r prosiect a fydd yn cael ei asesu ar lafar. 

Bydd pynciau fel arfer yn cynnwys gwaith ymarferol yn y labordy, ond mae prosiectau damcaniaethol yn bosib, mewn meysydd addas.


CH4405: Advanced Techniques in Biophysical Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH4405
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Niklaas Buurma
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

In this module, the application of biophysical and computational techniques to study interactions in biological and medicinal chemistry research will be discussed. 

Students will appreciate what information can be gained from each technique and learn how to plan experiments and interpret the resulting data.

On completion of the module a student should be able to

 

  • Decide which technique, or combination of techniques, is most appropriate to study interactions between biomacromolecules and between biomacromolecules and small molecules. 

  • Decide which technique, or combination of techniques, is most appropriate to obtain structural information for interactions between biomacromolecules and between biomacromolecules and small molecules. 

  • Interpret the results from biophysical and computational techniques. 

  • Critically assess the validity of results from biophysical and computational techniques on the basis of an understanding of the physical basis of these techniques. 

How the module will be delivered

The module is taught using a combination of online recordings, 10 two-hour interactive workshop-style lectures, and 2 one-hour tutorials, as detailed in the weekly module map. 

The online recordings present the required theory and students are required to watch the recordings before the corresponding interactive workshop-style lectures. 

The interactive lectures then apply the theory as presented in the recordings to exam-style problem-solving exercises. The module also includes a summatively assessed open-book exam-style in-class workshop. 

Skills that will be practised and developed

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future 

 

  

Graduate Attributes – Assessment:    

  

 Class Test                        20% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future 

 

 Exam                                80% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future 

 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:  

Goal 3. Ensure healthy lives and promote well-being for all at all ages         

How the module will be assessed

The module will be assessed through an open-book class test and an exam.

The summatively assessed open-book class test assesses the student’s ability to decide which technique, or combination of techniques, is most appropriate to study interactions between biomacromolecules and between biomacromolecules and small molecules; decide which technique, or combination of techniques, is most appropriate to obtain structural information for interactions between biomacromolecules and between biomacromolecules and small molecules; interpret the results from biophysical and computational techniques; critically assess the validity of results from biophysical and computational techniques on the basis of an understanding of the physical basis of these techniques. The open-book class test also serves as a practice exam.

The exam assesses the student’s ability to decide which technique, or combination of techniques, is most appropriate to study interactions between biomacromolecules and between biomacromolecules and small molecules; decide which technique, or combination of techniques, is most appropriate to obtain structural information for interactions between biomacromolecules and between biomacromolecules and small molecules; interpret the results from biophysical and computational techniques; critically assess the validity of results from biophysical and computational techniques on the basis of an understanding of the physical basis of these techniques. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session.

Reassessments take the same format as the original assessments. 

Assessment Breakdown

Type % Title Duration(hrs)
Class Test 20 Open-book Class Test N/A
Exam - Autumn Semester 80 Advanced Techniques in Biophysical Chemistry 2

Syllabus content

All content is mandatory.  

 

Spectroscopic techniques 

Principles of UV-visible, fluorescence, FRET, circular dichroism, vibrational circular dichroism spectroscopies as used in biophysical studies. The use of temperature-dependent spectroscopy to obtain thermodynamic data. Data acquisition and interpretation. 

 

Solution calorimetric techniques 

DSC and ITC. Data acquisition and interpretation. 

 

Other techniques 

Further biophysical techniques, including surface plasmon resonance (SPR); SPR instrumentation; SPR methods for determining equilibrium constants and kinetics; biolayer interferometry; SwitchSENSE; Mass spectrometry for study of biomolecules; electrochemical techniques and other modern techniques in biophysical chemistry. 

 

Data analysis 

Applications of biophysical techniques to the study of biomolecular structure and interactions, including data analysis and estimation of error margins. 

 

Structure-based methods 

Computer-based methods for docking small molecule ligands into protein binding sites; Introduction to developing and validating scoring functions to determine qualitative ligand binding free energies. 

Computing the energies of protein/ligand complexes using empirical force field methods; Molecular dynamics simulations and computer-based conformational sampling methods to obtain quantitative estimates of ligand binding free energies. 

 

Introduction to X-ray crystallography and cryogenic electron microscopy for acquiring atomic details of biomolecular structures and their complexes with small molecule ligands; overview of 1D and multi-dimensional Nuclear Magnetic Resonance (NMR) methods to determine the structure of biomolecules and protein/ligand complexes. 


CH4408: Modern Catalysis

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH4408
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Jennifer Edwards
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module demonstrates fundamental concepts in catalysis and expands on these to demonstrate how modern catalysis addresses major chemical and environmental challenges. These challenges include: 

 

  • Environmental air and water protection (through control of VOC and CO air emissions and chemical/biological remediation of wastewater), 

  • Using catalysis to provide clean energy (through the development of sustainable non-fossil fuel sources, and processes underpinning clean hydrogen generation), 

  • Upgrading low-value and waste products to provide alternative, non-fossil pathways to commodity and fine chemicals, 

  • Alternative sustainable pathways for hydrogen peroxide synthesis, and integration of parallel oxidation processes to generate high oxidation products in a more sustainable way, 

  • Fine and bulk chemical synthesis of chemicals crucial for modern living, 

  • Replacing supply-limited precious metal catalysts by less rare materials, 

 

The basic principles of catalysts synthesis will be covered, and the importance of complementary catalyst characterisation methods (to identify the active site) will be highlighted. 

Information on the physical properties of the catalyst will be used to demonstrate catalysts mechanisms. The content will draw strongly on the complementary fields of nanoscience, solid-state chemistry, surface science, organometallic chemistry, and synthetic organic chemistry.  

On completion of the module a student should be able to

On successful completion of the module, you should be able to: 

 

  • Describe the fundamental principles of structure, function, and activity of heterogeneous and homogeneous catalysts in modern catalytic processes, 

  • Evaluate experimental data from catalysts performance experiments and relate this to physical and chemical information describing catalyst structure and then use this to propose a catalytic mechanism solution. 

  • Apply concepts of homogeneous catalysis to propose hypotheses and detailed reaction mechanisms for homogeneous modern catalytic reactions, 

  • Describe how ligand design enables better chemo-, regio- and stereo-control in homogeneous catalysis 

  • Propose original catalytic solutions to emerging real-world problems and suggest potential catalysts for unseen problems. 

How the module will be delivered

You will receive course content delivered primarily using face to face lectures. The course consists of 10 x 2-hour lectures during the Spring semester, with approximately 3 lectures a week for 3-4 weeks. 

Lectures may include some worked problems and informal formative questions to support principles introduced. These will help you to address the learning outcomes and provide opportunities to apply knowledge and develop understanding. 

The lecture schedule will follow the module map published prior to the start of the module. Lectures will be recorded and will be available following the live sessions. A combination of lecture slides and additional supporting notes will be available for you prior to the face-to-face lectures. 

Lecture material will be supported by two workshops. These are formative and will take the form of face-to-face sessions, and these will focus on supporting problem solving based on material from lectures. 

These formative workshops will provide you with guidance and support for the assessed coursework and examination A single summative coursework assessment will be released after the final lecture. 

Skills that will be practised and developed

Skills developed through formal module learning outcomes and summative assessment include: 

 

Academic Skills: 

 

  • In the workshop you will take part in a group exercise where a solution is developed that applies theories taught in a lecture to a scaled, real-world problem. This exercise will allow you, as a team, to generate original ideas and apply and innovative solution based on the specific needs of the real-world solution. The teamwork aspect allows you to collaborate in a positive way and will develop your verbal communication skills. 

 

  • One option in the summative assessment involves a critical assessment of text generated by AI where the topic is related to one of the lectures. This builds on critical thinking and gives an opportunity to present your own interpretation of the text and communicate this is a succinct and effective manner. 

 

 

Chemistry-Specific Skills: 

 

  • You will develop chemistry specific skills, focussed on applying ideas from fundamental physical and inorganic chemistry to understand how these can be applied to provide solutions in modern catalysis applications. The topics covered relate to global issues such as Net Zero, water scarcity and renewable energy. Knowledge of these areas of chemistry will help develop your ethical, social, and environmental awareness. 

 

  • Developing these skills will allow you to start to select appropriate catalysts for specific target reactions with some awareness of stakeholder needs (individuals, organisation). You will develop skills in translational catalytic application by understanding the wider content that emerging modern chemical challenges present and developing and adapting established catalysis processes to address them. 

 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future 

 

  

Graduate Attributes – Assessment:    

  

Written Assessment               20% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future 

 

Exam                                      80% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future 

 

 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 3. Ensure healthy lives and promote well-being for all at all ages

Goal 6. Ensure availability and sustainable management of water and sanitation for all  

Goal 7. Ensure access to affordable, reliable, sustainable, and modern energy for all  

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation

Goal 11. Make cities and human settlements inclusive, safe, resilient, and sustainable  

Goal 13. Take urgent action to combat climate change and its impacts 

How the module will be assessed

Summative assessment will take the form of a written examination and a written piece of coursework.

A two-hour closed book written exam will test your ability to demonstrate knowledge and understanding of the syllabus content, and your ability to apply the techniques and concepts covered to problems solving that are related to familiar and unseen examples. 

The summative coursework will allow you to demonstrate your ability to review and evaluate research from the literature through the preparation of a short-written report (2 pages). You will be able to choose between 2 questions relating to homogeneous or heterogeneous catalysis and will need to identify how original, peer reviewed research articles can be used to address the specific problem outlined. You will receive feedback on your coursework well before the written exam.

Your learning will also be supported by the formative workshops, and feedback provided either orally or in writing during and after the sessions. There will be a focus on supporting problem solving based on applying knowledge and understanding of modern catalyst approaches for unseen, emerging applications. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Coursework N/A
Exam - Spring Semester 80 Modern Catalysis 2

Syllabus content

The syllabus will cover 3 main themes: 

 

(a) Catalysts for environmental protection - This part of the module concentrates mainly on catalytic treatment of emissions from stationary sources. This will also focus on the removal of biological and chemical contaminants from water (in both industrial and domestic settings). This theme also focusses on clean energy, with green carbon sources discussed, and the hydrogen economy (and the catalytic processes that provide it) emphasised. There is further emphasis on the fundamental underlying aspects of the chemistry, in respect to catalyst preparation, microscopic, macroscopic, and surface structure, and probing the catalytic mechanism. 

 

(b)  Homogeneous catalysis in the 21stcentury - This part of the module considers how established homogeneous catalytic systems can be improved in terms of both cost and environmental impact.  In particular, application of the principles of ‘green catalysis’ will be emphasised with regard to the nature of the catalyst, the chemical process itself and greener alternatives to established materials. 

 

(c)  Grand challenges for catalysis –Fundamental catalyst studies can be translated to technology and process improvements, where lab scale discoveries are exploited on a commercial level, improving process efficiency using less toxic catalyst materials. Examples of novel and more sustainable production routes of fine and commodity chemicals will be explored. The processing of waste streams (with emphasis on non-fossil source) to value added chemicals will be illustrated. Integration of heterogeneous catalysis processes into chemical synthesis routes to provide less energy intensive chemical synthesis will be demonstrated. 

 

Essential Reading and Resource List 

 ‘Handbook of Green Chemistry – Green Catalysis’: Vol. 1 Homogeneous Catalysis; Vol. 2 Heterogeneous Catalysis, eds. P. Anastas and R.H. Crabtree, Wiley VCH, 2009 

“Grand challenges for catalysis in the Science and Technology Roadmap on Catalysis for Europe: moving ahead for a sustainable future” P. Lanzafame, S. Perathoner, G. Centi, S. Gross, E.J.M. Hensen, Catal. Sci. Technol., 2017, 75182-5194. 


CH4409: Applications of Advanced Spectroscopic Methods

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH4409
External Subject Code 101050
Number of Credits 10
Level L7
Language of Delivery English
Module Leader PROFESSOR Philip Davies
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

Spectroscopy is one of the central pillars of chemistry, providing essential information on the reactants, products and critically, intermediates, involved in every chemical reaction studied. In this module, we discuss applications of spectroscopy across a very broad range of fields with a particular emphasis on interfacial and atmospheric processes where Cardiff has particular expertise. 

The module describes some aspects of the cutting edge of research being undertaken in the School and discusses the unique tools being exploited at Cardiff to investigate these areas. 

On completion of the module a student should be able to

  • Describe a range of experimental methods for determining surface structural and spectroscopic information.  

  • Explain the basic concepts underpinning a range of surface sensitive techniques and use that knowledge to understand experimental data generated by the techniques.  

  • Describe the difference between electron microscopy techniques, including scanning electron microscopy and transmission electron microscopy. 

  • Critically evaluate why electron microscopy and aberration-correction is required for atomic-resolution imaging. 

  • Apply understanding of spectroscopic techniques in the electron microscope to determine composition and oxidation state of sample data. 

  • Describe Wood’s system of surface structure notation and demonstrate its application in new situations. 

  • Explain why there are problems inherent in obtaining information from surfaces under ambient conditions, and of the techniques being employed to address these problems. 

  • Interpret data acquired from a range of surface sensitive spectroscopies and microscopies 

How the module will be delivered

The module will be delivered in 10 two-hour lectures, supplemented by 3 one-hour formative class tutorials. 

Skills that will be practised and developed

Chemistry-Specific Skills:

 

  • The skills practiced in this module that relate to the Cardiff graduate attributes, are indicated with “GA” and bold type. 

  • The module aims to create an awareness of the special problems of studying the nanoscale and the interface region and the tools that are available to address those problems. 

 

  • Students will be trained to identify the special circumstances of spectroscopy in these fields, to recognise the information that can be obtained and the best choice of tools to gather that data and finally in the methods that can be used to extract useful information from the data the different microscopies and spectroscopies produce. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future 

 

  

Graduate Attributes – Assessment:    

  

 Coursework                 20% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future 

  •  

 

 Exam                           80%  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future 

 

   

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:  

 

Goal 6. Ensure availability and sustainable management of water and sanitation for all  

Goal 7. Ensure access to affordable, reliable, sustainable, and modern energy for all  

Goal 12. Ensure sustainable consumption and production patterns  

Goal 13. Take urgent action to combat climate change and its impacts

Goal 14. Conserve and sustainably use the oceans, seas, and marine resources for sustainable development 

How the module will be assessed

Summative assessment will consist of two parts: 

  • One two-hour exam consisting of four compulsory questions reflecting the three elements of the course. 

  • One piece of written coursework which will take approximately 2 hours to complete and will consist of a set of questions from across the module syllabus.  

 

Formative Assessment 

  • For each of the three segments of the course, a worksheet of questions will be issued and discussed at a scheduled “tutorial” allowing students the chance to assess their competence. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 20 Workshop N/A
Exam - Spring Semester 80 Applications of Advanced Spectroscopic Methods 2

Syllabus content

Fundamental principles of interface spectroscopy and microscopy

 

  • Fundamental limitations of spectroscopy at interfaces and methods of addressing them 

  • Advanced experimental methods for exploring interface science 

  • Surface structures and conventions for describing them 

  • Experimental methods for exploring surface structure 

  • Use of scanning electron microscopy and transmission electron microscopy for understanding material structure. 

  • EELS and EDXS for determining composition and oxidation state. 

  • Factors influencing resolution of electron microscopy. 

  • The unique advantages and applications of synchrotron light sources for probing interface environments 

  • XPS, XAFS and real-time “operando” measurements applied to metallic and oxide catalytic surfaces in situ 


CH5401: Project

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5401
External Subject Code 100417
Number of Credits 80
Level L7
Language of Delivery English
Module Leader Dr Paul Newman
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module consists of a supervised research project spread over two semesters, selected from a portfolio prepared by members of staff from their own research interests. The work will largely require new studies in which a problem at the leading edge of a current area of Chemistry will be tackled using original research. In addition, the module will require all students to carry out a detailed literature survey, and preparation of a draft and final project report as well as a presentation, which will be examined orally. 

On completion of the module a student should be able to

  • Communicate effectively, using a range of methods, articulating academic ideas and technical arguments in manners appropriate to both specialist and non-specialist audiences. 

 

  • Devise experiments and/or simulations, carry them out and analyse the outcome. 

 

  • Independently evaluate results and disseminate in both report and oral format, defend them under questioning.  

 

  • Demonstrate initiative and independence by taking responsibility for structuring and time-managing a research task. 

 

  • Research and study creatively and independently, applying advanced knowledge and skills to unfamiliar topics or contexts. 

 

 

How the module will be delivered

 

Independent investigation, both in research laboratories and library, supervised by a member of academic staff and/or their nominee from research group. You will be required to regularly produce pieces of written work for formative or summative feedback throughout the duration of the project.  

 

Skills that will be practised and developed

 

Chemistry-Specific Skills: 

 

On completion of the module, you will be able to: 

 

  • Plan and carry out an original investigation in a topic from any part of practical or theoretical chemistry. 

  • Select source literature and place it within the context of the project, with critical assessment of preceding work. 

  • Record working notes in an appropriate manner, with reference to risk and hazard where applicable. 

  • Plan and compose a detailed report in standard format on all aspects of the project; 

  • Present a lecture about the work and answer questions in oral examination. 

 

  

Employability skills:     

   

This module is delivered and aligns with the following University Graduate Attributes:   

 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Demonstrate enthusiasm and the ability to motivate themselves and positively influence others in meeting agreed responsibilities. 

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience. 

  • Listen to and take account of the views of others. 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate and present with impact. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path. 

  • Understanding organisations, their stakeholders and their impact on the economy 

  • Actively reflect on own studies achievements and self-identity 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

Graduate Attributes – Assessment:   

 

Dissertation 40% 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate and present with impact. 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Practical based assessment 20% 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

 

Presentation 20% 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate and present with impact. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Oral/aural Assessment 20% 

  • Listen to and take account of the views of others. 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate and present with impact. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Sustainable Development Goals:      

 

This module does not align with any of the Sustainable Development Goals, but its topics do underpin all.   

How the module will be assessed

The module will be assessed on the basis of performance in the laboratory, a written report, an oral presentation and an oral (viva voce) examination. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Given the weighting of this module, if you fail, you will have to repeat the year.  

Assessment Breakdown

Type % Title Duration(hrs)
Dissertation 40 Written Report N/A
Practical-Based Assessment 20 Intellectual and/or Practical Contribution N/A
Presentation 20 Oral Presentation N/A
Oral/Aural Assessment 20 Oral Examination N/A

Syllabus content

This module consists of one supervised research project spread over two semesters, in any suitable area of chemistry. The work will include new studies, a literature survey, and preparation of a project report and a presentation, which will be examined orally. Topics will normally involve practical laboratory work, but projects with a large theoretical and/or data-based component are also possible, in appropriate areas. 


CH5402: Metals in Medicine and Bioimaging

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5402
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Dr Benjamin Ward
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

 

This module will cover modern aspects of inorganic coordination chemistry, including the design of d- and f-block coordination complexes and metal-based nanoparticles for application in bioimaging techniques and medicine. It will set out the ways in which ligands and complexes can be designed to achieve desired properties and functionality. It will examine a range of bioimaging techniques (including, magnetic resonance imaging, radioimaging and luminescence microscopy), including their underlying principles, and show how different metal complexes can be designed for these applications, including for the visualisation of cellular function and diagnosis of disease. Aspects of synthesis, spectroscopic characterisation and molecular design will be described, as will ways to rationalise the relationship between structure and function. This will lead to the description and case study analysis of responsive probes, bimodal systems, biological targeting, and theranostic agents.  

On completion of the module a student should be able to

Describe synthetic chemistry pathways to target ligands, complexes and nanoparticles. 

Interpret spectroscopic and physical data and appreciate how variations in structure relates to function in different biological contexts.     

Appreciate the design of metal-based species for biological environments, and how this influences the design of supporting ligands and nanoparticles. 

Describe the fundamental concepts and principles, and the advantages and disadvantages, associated with different bioimaging techniques, especially in the context of visualisation of cellular functions and diagnosis of diseases. 

Critically analyse literature-based examples thereby demonstrating a knowledge of the design criteria of metal-based agents for biological applications 

How the module will be delivered

Content will be delivered primarily using lectures.  

Formative workshops will be used to discuss case studies from the literature, enhance and assess problem-solving skills related to the critical analysis of data, and demonstrate application of knowledge. 

Skills that will be practised and developed

 

Academic Skills:  

  • Interpret complex scientific information and relate to properties of different classes of coordination complexes 

  • Understanding what kind of information (including visualisation of cellular processes; disease states) is provided by different bioimaging techniques  

  • Develop effective skills focussed upon reviewing primary literature and extracting relevant    information  

 

Chemistry-Specific Skills: 

  • You will appreciate ligand structure and bonding in metal complexes and be able to apply concepts of targeted molecular design to more complicated scenarios;  

  • You will learn how to analyse datasets and to formulate an explanation for observations of physical properties, thereby developing a level of understanding closer to situations expected in graduate-level employment.   

  • You will refine your problem-solving skills in situations that require them to synthesise a coherent argument or explanation using knowledge/data from a number of different sources.  

 

Employability skills:     

   

This module is delivered and aligns with the following University Graduate Attributes:   

 

  • Contribute to discussions, negotiate and present with impact. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Actively reflect on own studies achievements and self-identity 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future.  

  

   

Graduate Attributes – Assessment:     

   

Exam           70% 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Written assessment             30% 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information, including primary literature. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change 

  • Identify and articulate own skills, knowledge and understanding confidently 

Sustainable Development Goals:       

 

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

  • Goal 3. Ensure healthy lives and promote well-being for all at all ages 

  • Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

How the module will be assessed

  

Summative coursework assessment (30%) workshop is a take-home assessment that requires engagement and analysis of the primary literature – it is a word count limited written report. This will assess your ability to use electronic databases, locate relevant scientific information and critically review the primary literature. This will assess your knowledge of molecular design and a deep understanding of the physical parameters that dictate the biological potential and application of your chosen system.   

  

A written exam (3 hour, 70%) will test your ability to demonstrate your deep knowledge and understanding of the syllabus content, and your ability to apply the techniques/concepts covered to unseen problems.   

  

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

  

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 30 Written Assignment N/A
Exam - Spring Semester 70 Metals in Medicine and Bioimaging 3

Syllabus content

 

Fundamental aspects of coordination chemistry in medicine: solubility products, formation constants,ligand pKa, coordination complexes of d- and f-block metal ions; organometallic and cyclometalated complexes; understanding biocompatibility, targeted design, bioconjugation and responsive systems 

 

Ligand design: chelating, multidentate and macrocyclic variants, siderophores, bioconjugation 

 

Optical imaging using Luminescence   

Background on confocal fluorescence microscopy for cellular imaging  

Background on photophysics – Stokes shift, Jablonski diagrams, time resolved vs steady state measurements, quenching pathways, types of emission, tuning emission through ligand design.  

Types of transition metal-based luminophore. Types of lanthanide(III)-based compounds. Upconverting nanoparticles.  

 

Magnetic Resonance Imaging and Contrast Agents  

Background on magnetic resonance imaging. Background on the fundamental properties and design of T1 and T2 contrast agents. Pulse sequences. Types of complexes used for T1 and T2 contrast. Assessing new contrast agents –solubility, stability and the NMRD. Molecular agents and nanoparticle systems. 

  

Gamma Radio-Imaging via SPECT and PET   

Background to gamma imaging – physical basis of the techniques, data capture and imaging.  
Single Photon Emission Tomography (SPECT). Positron Emission Tomography (PET). 
General properties of PET/SPECT isotopes, half-lives, imaging resolution, biological matching.  

Background to functional imaging vs. structural imaging. Types of molecular agents. 
 

Multimodal Imaging agents 

Understanding design principles and critical analysis of applications 

 


CH5403: Molecules for Health and Life

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5403
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Professor Thomas Wirth
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module will describe modern aspects of organic, biological and medicinal chemistry. Building on the required previous modules CH4302 and CH4303, it will introduce advanced methods for control in the synthesis of target molecules. It will explain in detail how preparation of enantiomerically pure molecules is achieved, for example in pharmaceuticals, and describe development of stereoselective reactions as well as various enabling technologies such as electrochemistry, photochemistry, organo- and enzyme catalysis and flow synthesis including automation. It will set out how molecular synthesis can be targeted towards specific applications, such as medicinal chemistry or sustainability. It will also explain application of biophysical techniques to study interactions in biological and medicinal chemistry research, and methods for simulation of molecules of importance to life and health. Throughout, the ability to extract chemically relevant information from complex systems will be a major focus. 

 

On completion of the module a student should be able to

  • Appreciate the range of synthetic methods, strategies and reagents available to prepare challenging synthetic targets, including enantiomerically pure molecules.  

 

  • Explain the main principles in the use of enabling reaction technologies and related industrial issues together with application to target molecules. 

 

  • Identify the key inter- and intramolecular interactions that determine biomolecular structure and drug-receptor binding. 

 

  • Decide on technique(s) appropriate to study interactions between biomacromolecules and between biomacromolecules and small molecules.  

 

  • Appreciate molecular modelling and simulation methods suitable for studying problems in medicinal and biological chemistry. 

 

  • Interpret and critically assess the results from biophysical and computational techniques.  

How the module will be delivered

Content will be delivered through a combination of approaches, including lectures, pre-recorded content and problem-solving workshops. Contact time, in the form of lectures or problem-solving workshops, is 40 h across two semesters, equating to approximately two sessions per week. Support for learning will include informal ad hoc formative tests.  

  

Workshops and tutorials will be used to enhance and assess problem-solving skills related to the retrieval and analysis of data. 

Skills that will be practised and developed

Chemistry -Specific Skills: 

 

  • Development of detailed understanding of how molecular structures are related to specific usages, and how these structures can be formed through organic synthesis. 

 

  • Approaches to evaluate the success of molecules addressing targets of biological interest will be trained and the accompanying data analysis approaches will be developed. 

 

  • The module will also involve a large element of problem solving using both numerical and algebraic techniques, based around real examples of experimental and theoretical data. 

 

Employability skills:     

   

This module is delivered and aligns with the following University Graduate Attributes:   

 

Contribute to discussions, negotiate and present with impact. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Actively reflect on own studies achievements and self-identity 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future.  

  

   

Graduate Attributes – Assessment:     

   

Exam                    70% 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Written assessment                    30% 

  • Contribute to discussions, negotiate and present with impact. 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Sustainable Development Goals:       

    

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

  • Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture  

  • Goal 3. Ensure healthy lives and promote well-being for all at all ages 

  • Goal 7. Ensure access to affordable, reliable, sustainable and modern energy for all 

  • Goal 8. Promote sustained, inclusive and sustainable economic growth, full and productive employment and decent work for all 

  • Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

How the module will be assessed

A written exam (3 h) will test your ability to demonstrate your knowledge and understanding of the syllabus content, and your ability to apply the techniques/concepts covered to unseen problems. A single piece of coursework will allow you to demonstrate knowledge of key concepts and apply that knowledge to chemical problems. Marks will reflect the extent to which you have met the module learning outcomes shown above. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Presentation 30 Recorded presentation N/A
Exam - Spring Semester 70 Molecules for Health and Life 3

Syllabus content

Organic synthesis and stereoselective chemistry. Applications in total synthesis and the synthesis of bioactive compounds and labelled molecules.  

 

Enabling tools for organic synthesis: microwave reactors, photochemical reactors, electrochemistry and flow chemistry, radionuclide chemistry.  

 

Synthesis automation, machine learning and AI in synthesis and bioorganic chemistry. 

 

Molecular recognition in biology. Biomolecular interactions, structure of essential building units. Supramolecular chemistry in biotechnological applications. 

 

Biophysical techniques: key principles of spectroscopies used in biophysical studies. Calorimetry: DSC and ITC. Surface-based techniques in biophysical chemistry; electrochemical approaches to studying interactions. Data acquisition and interpretation, analysis and estimation of error margins. 

 

Supramolecular chemistry in biology: nucleic acid and protein as well as their applications, spanning form small molecule synthesis, artificial enzyme design and antibody-drug conjugate creation.  

 

Molecular modelling for molecules of life: parameterised methods, potential energy surfaces, forces, local and global optimisation, dynamics 


CH5404: Modern Materials

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5404
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Dr Alison Paul
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

 

  • The module aims to develop an understanding of the synthesis, formulation, characterisation, simulation of advanced materials relevant to the development of materials for modern world applications.  

  • It will set out how modern chemistry goes beyond the single molecule, analysing the driving forces for the association between molecules and/or ions that are induced by non-covalent bonding interactions in solution, solid-state and at interfaces. Relating these qualities to bulk material behaviour through the understanding of important structure – property relationships, the module will link fundamental principles to the informed design of modern materials, including consideration of potential commercial feasibility and reduction of environmental impact. 

  • It will describe materials such as nanoparticles, colloidal systems, crystalline and amorphous solids, and supramolecular architectures in 2- and 3-dimensions. The course will set out methods for determining and modelling their structural, dynamic, and electronic properties, including static, time-resolved and spatially resolved analyses. 

 

On completion of the module a student should be able to

  • Describe how different methods for synthesising and formulating advanced materials can impact on their performance in different applications.   

  • Evaluate and predict key properties of materials based on modelling and characterisation data.  

  • Analyse experimental/characterisation/modelling data for different advanced materials to probe the material properties and establish an understanding between structure, composition, and chemistry.  

  • Explain the importance of time-resolution and spatial-resolution in analytical measurements on modern materials and describe what additional information these methods provide in comparison to static techniques. 

  • Explain key concepts of molecular recognition in biology and apply these to the structure and function of biomaterials.  

  • Critically assess literature relating to advanced materials properties and applications. 

How the module will be delivered

 

  • Content will be delivered primarily via lectures (40 h across two semesters, equating to approximately two lectures per week). Lectures will include discussion activities, worked problems and informal ad hoc formative tests.  

  • Workshops and tutorials will be used to enhance and assess problem-solving skills related to the retrieval and analysis of data. 

 

 

Skills that will be practised and developed

 

Chemistry-Specific Skills:  

 

  • Applying ideas from fundamental chemistry to understand how properties of molecules, solids and surfaces are utilised in the design of modern materials with specific target properties. 

 

  • You will practise data interpretation skills, extending your skills to multi-component systems. 

 

  • You will develop a detailed understanding of how properties of molecules and materials are related to their electronic structure, and how these properties are related to observed behaviour and spectra.  

 

  • The module will also involve a large element of problem solving using both numerical and algebraic techniques, based around real examples in materials chemistry. 

 

Employability skills:     

   

This module is delivered and aligns with the following University Graduate Attributes:   

 

Contribute to discussions, negotiate and present with impact. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Actively reflect on own studies achievements and self-identity 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future.  

  

Graduate Attributes – Assessment:     

   

Exam:     

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Written assessment:   

  • Contribute to discussions, negotiate and present with impact. 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Sustainable Development Goals:       

    

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

  • Goal 8. Promote sustained, inclusive and sustainable economic growth, full and productive employment and decent work for all 

  • Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

  • Goal 11. Make cities and human settlements inclusive, safe, resilient and sustainable 

  • Goal 13. Take urgent action to combat climate change and its impacts 

How the module will be assessed

A written exam (3 h) will test your ability to demonstrate your knowledge and understanding of the syllabus content, and your ability to apply the techniques/concepts covered to unseen problems. A single piece of coursework will allow you to apply knowledge to chemical problems through critically assessment and evaluation of methods for the synthesis, characterisation and application of materials, thereby demonstrating knowledge and understanding of key concepts. Marks will reflect the extent to which you have met the module learning outcomes shown above. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Class Test 30 Coursework - Class Test N/A
Exam - Spring Semester 70 Modern Materials 3

Syllabus content

Self-assembly and self-organization in colloidal formulations of surfactants, polymers and particles. Structure activity relationships and interaction between components in formulations, including supporting case studies. Advanced methods for the characterisation of nanoscale structure and bulk properties. Applications in industry and healthcare. 

 

Thermodynamics and kinetics of host-guest processes of biomacromolecules. Non-covalent interactions in solid-state and solution. Dynamic covalent bonds & supramolecular polymers. Molecular machines.  

 

Experimental techniques and methods for nanoscale and ultrafast chemistry for supramolecular processes. 

 

Fundamental properties of advanced materials in technological applications. Properties and applications of semiconducting materials, and the impact of defects. Properties of interfaces and surfaces on geometric, energetic and electronic properties.  

 

Solid-state NMR spectroscopy. Theoretical background and experimental techniques. Anisotropic NMR interactions in solid materials. Techniques for recording broad-line and high-resolution solid-state NMR spectra. Applications of solid-state NMR to investigate structural and dynamic properties of solids. 

 

Simulation of materials. Atomistic and electronic structure methods. Calculation of static, dynamic and electronic properties of solids. Periodic density functional theory and forcefield approaches.  


CH5405: Catalysis and Interfaces for Sustainable Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5405
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Dr Jennifer Edwards
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module will cover the synthesis, characterisation and simulation of the catalytic materials that find applications in the development of sustainable chemicals production and energy sectors.  

 

The need to reduce our dependence on fossil sources of carbon for chemicals and fuels is giving rise to a whole new set of challenges in catalysis. The module will introduce pathways used to transform renewable resources into useful chemicals and emphasize how characterisation and simulation lead to understanding which helps to design and optimise catalytic materials.  

 

It will also address current issues in environmental chemistry, including use of catalysis to address clean air, water and energy generation. It will explain how fundamental properties of solids, surfaces and nanoparticles can be related to catalytic activity.  

 

You will develop critical analysis skills through study of literature case studies and quantitative approaches to defining how environmentally friendly a chemical process really is. 

On completion of the module a student should be able to

 

  • Appreciate the fundamental principles of structure, function and activity of heterogeneous catalysts in modern catalytic processes, Green Chemistry and energy sectors. 

  • Evaluate experimental data from catalysts performance experiments and relate this to physical and chemical information describing catalyst structure and then use this to propose a catalytic mechanism solution. 

  • Describe common structural features of heterogeneous catalysts and how these relate to activity. 

  • Appreciate the range of techniques that can be used to characterise catalyst and surface structures, and how these can be used to explain and predict activity. 

  • Describe in situ measurements that are used to scope out elementary surface reactions during catalysis. 

  • Explain the main computational chemistry approaches used in the simulation of catalytic materials and catalysed reactions. 

 

 

How the module will be delivered

 

  • Content will be delivered primarily using lectures (40 h across two semesters, equating to approximately two lectures per week). In addition, lectures will include worked problems and informal ad hoc formative tests.  

  • Workshops and tutorials will be used to enhance and assess problem-solving skills related to the retrieval and analysis of data. 

Skills that will be practised and developed

 

Chemistry-Specific Skills: 

 

  • Applying ideas of catalysis to appreciate how catalytic systems can be designed and interrogated using experimental and simulation techniques.  

  • You will develop a detailed understanding of how properties of materials are related to their catalytic activity, and how these properties can be controlled.  

  • The module will also involve a large element of problem solving using both numerical and algebraic techniques, based around real examples of theoretical methods. 

  • The module is centred in sustainable chemistry, and you will also acquire the vocabulary and analytical skills to exercise critical judgement regarding the contribution a particular catalytic process can make to improving the environment and reducing the impact of anthropogenic activity. 

 

Employability skills:     

   

This module is delivered and aligns with the following University Graduate Attributes:   

 

Contribute to discussions, negotiate and present with impact. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Actively reflect on own studies achievements and self-identity 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future.  

  

Graduate Attributes – Assessment:     

   

Exam               70% 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Written assessment                30% 

  • Contribute to discussions, negotiate and present with impact. 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Sustainable Development Goals:       

    

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

  • Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture  

  • Goal 3. Ensure healthy lives and promote well-being for all at all ages 

  • Goal 6. Ensure availability and sustainable management of water and sanitation for all 

  • Goal 7. Ensure access to affordable, reliable, sustainable and modern energy for all 

  • Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

  • Goal 12. Ensure sustainable consumption and production patterns 

 

How the module will be assessed

A written exam (3 h) will test your ability to demonstrate your knowledge and understanding of the syllabus content, and your ability to apply the techniques/concepts covered to unseen problems. A single piece of coursework will allow you to demonstrate knowledge of key concepts and apply that knowledge to chemical problems. Marks will reflect the extent to which you have met the module learning outcomes shown above. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Class Test 30 Coursework - Class Test N/A
Exam - Spring Semester 70 Catalysis and Interfaces for Sustainable Chemistry 3

Syllabus content

 

The module will cover the synthesis of catalytic materials which can underpin sustainable chemicals and energy sectors. The principals of Green Chemistry will be reviewed with current literature examples of industrial processes that have been superseded by more sustainable chemistry. The characterisation methods used to measure properties such as the solid phases present, the effective surface area of catalysts and spectroscopic inspection of working catalysts will be addressed alongside high-resolution microscopy capable of giving atomic level images of catalytic materials. The main approaches to the computer simulation of catalytic materials will also be introduced, with examples that integrate with the theme of Sustainable Chemistry drawn from the literature. Reaction schemes will be presented and discussed based on calculated potential energy surfaces and the insights these given into the catalytic processes they represent. The overall aim of the module is to demonstrate how materials characterisation and simulation can help to inform a mechanistic understanding of heterogeneous catalysis using key reactions as exemplars.    

 


CH5406: Frontiers in Inorganic Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5406
External Subject Code 101043
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Dr Benjamin Ward
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module will focus on the structure, influence, and design of ligands and compounds in the development of functional metal complexes and main-group compounds.  Four areas will be covered, representing a cross section of pertinent problems in this area, these will be a) metal complexes for catalytic polymerisation and depolymerisation; b) the study of N-heterocyclic carbene complexes and their catalytic chemistry; and c) the stoichiometric and catalytic reactions of frustrated Lewis pairs; d) advanced aspects of homogeneous catalysis for sustainable chemical synthesis.  The module will cover the synthesis of ligand precursors, coordination chemistry, including in cases where there is no electronic preference to coordination geometry, and homogeneous catalysis.  Attention will be given to the analysis of structure-activity relationships and the interpretation of catalytic data in terms of reaction mechanisms. The module highlights the use of inorganic chemistry for sustainable chemical processes and aligns with UN STGs 9, 12, 13, 14, and 15.

On completion of the module a student should be able to

  1. Formulate a catalytic reaction mechanism within unfamiliar operating parameters (e.g. catalyst and/or substrate structure).

 

  1. Critically evaluate catalytic reaction data in terms of the likely reaction mechanism, substrate structure, and catalyst design; assess structure-reactivity effects of ligands and formulate reactivity patterns.

 

  1. Design an appropriate synthetic strategy for ligands and complexes within provided constraints.

 

  1. Choose appropriate analytical techniques to characterise chemical species and assess analytical data in terms of chemical structure.

How the module will be delivered

The module will be delivered in 20 2-hour lectures and four 1-hour tutorials.

The module consists of four distinct blocks, each covering a different aspect of advanced inorganic and coordination chemistry. The four blocks will mirror the three sections described above: (a) the production and chemical recycling of polymers, including traditional polyolefins and modern alternatives; (b) metal complexes bearing N-heterocyclic carbene ligands in catalysis for sustainable chemical synthesis; (c) the role of frustrated Lewis pairs in catalysis; and (d) modern aspects of coordination chemistry relating to catalysis. Each block will be followed by a tutorial in which problem-solving and analytical skills are practised.

Skills that will be practised and developed

 

Students will already know how to construct a catalytic mechanism for simple catalysts and substrates (level 6); in this module students will learn how to analyse complex datasets and to formulate an explanation for trends and observations of chemical reactivity patterns, thereby developing a level of understanding closer to situations expected in graduate-level employment. Students will relate ideas relating to functional metal complexes to a modern understanding of sustainable chemistry and will be able to construct a cost-benefit analysis of making chemical processes aligned to the UN Sustainable Development Goals. Students will refine their problem-solving skills in situations that require them to synthesise a coherent argument or explanation using knowledge/data from several different sources.

 

Graduate Attributes

Students will learn how to identify, define and analyse complex issues and ideas, exercising critical judgement in evaluating sources of data, centred around the properties of matter at microscopic and macroscopic scales and underpinned by the constraints and targets of sustainable development.

How the module will be assessed

Formative assessment will be provided in the three tutorial sessions following each of the four theory blocks. These tutorials will be interactive and will develop the problem-solving skills required to apply the core lecture material to unfamiliar situations.

Summative assessment will take the form of coursework (30%) and written examination (70%). Coursework will consist of a single piece of work of three 10-mark questions; each question will be problem-based and will require students to apply concepts of ligand design to synthesise catalytic mechanisms within unfamiliar operating parameters. This will allow students to meet learning objectives 1 and 2.

The examination will consist of four 20-mark questions; students must answer any three. Questions will probe students’ ability to interpret data and to construct mechanistic arguments based on provided data, thus allowing students to meet learning objectives 3-4.

Marking criteria

50-60 Satisfactory appreciation of the key concepts of catalyst design and their structural influence on catalytic reactions. Work in this category will demonstrate the ability to design catalytic cycles to an unfamiliar substrate and/or catalyst that are similar (but not identical) to those given in lecture material. There will also be a demonstrable ability to construct a ligand and/or catalyst synthesis from the molecular types illustrated in the lecture material.

60-70 Good grasp of most concepts relating to catalyst performance in relation to catalyst and substrate structure. Will demonstrate the ability to relate material from across all areas of the course to synthesise a rational explanation for catalyst performance and chemical reactivity. Will be able to propose a more advanced chemical synthesis pathway and an appreciation for how analytical techniques can aid the understanding of catalyst performance.

70-100 Excellent demonstration of catalyst design and structural influence on catalytic reactions. An outstanding ability to make connections between different areas of knowledge to aid a thorough interpretation of unfamiliar data, providing a rigorous spectroscopic/mechanistic/structural analysis. The ability to demonstrate appropriate weighting in different parameters that can affect chemical reactivity as applied to an unfamiliar situation.

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session.

 

The resit examination will adopt the same format as the main examination but will contain questions that allow students to demonstrate learning objectives 1-4.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 30 Written Assignments N/A
Exam - Spring Semester 70 Frontiers in Inorganic Chemistry 3

Syllabus content

The applications of ligand design and coordination chemistry to a range of areas, including catalysis and p-block chemistry, with an emphasis on the ability of controlling the properties and reactivity of metal complexes by ligand design.

The past and future of polymerisation catalysis

A detailed mechanistic understanding of the properties and reactivity of d0 metal alkyl and alkyl cations will be discussed.  These complexes have most widely studied in the context of alkene polymerisation, and this type of reactivity will be used to exemplify the reactivity of d0 complexes.  The level of detail moves on from that covered in level 6, encompassing the catalyst structures required for the production of stereospecific polymers and the influence of agostic interactions to facilitate migratory insertion reactions.  This theme will be expanded to introduce the polymerisation of cyclic esters, commonly used as biodegradable polymers, and then ultimately to the forefront of polymerisation research where ring-opening co-polymerisation of CO2/epoxides and anhydrides/epoxides will be covered in detail. Approaches for depolymerisation catalysis by metal complexes will be covered.

Heterofunctionalisation catalysis

The role of d0metal complexes as catalysts for a range of organic transformations will be discussed, with particular focus on hydroamination, hydrogenation, hydrosilylation, and hydrophosphination.  A particular focus will be given to looking at the mechanisms of these reactions, for which there are less reaction steps possible (e.g. oxidative addition is precluded). This theme will be expanded to cover alkaline earth metals in catalysis, including their environmental benefits, their scope, and their limitations.

Homogeneous catalysis in the 21st century

This part of the module considers how established homogeneous catalytic systems can be improved in terms of both cost and environmental impact.  In particular, application of the principles of ‘green catalysis’ will be emphasised with regard to the nature of the catalyst, the chemical process itself and greener alternatives to established materials. The development of N-heterocyclic carbenes will be discussed, in relation to their synthesis, coordination chemistry, and catalytic applications. Comparisons will be drawn between NHC complexes and those bearing alternative ligands.

p-Block organometallics

Introduction to p-block organometallics, including structure and reactivity trends will be provided. This will lead to a detailed discussion of frustrated Lewis pairs (FLPs), and their role in catalysis.


CH5451: Prosiect

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH5451
External Subject Code 100417
Number of Credits 80
Level L7
Language of Delivery Welsh
Module Leader Dr Paul Newman
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

Mae’r modiwl hwn yn cynnwys prosiect ymchwil dan oruchwyliaeth dros ddau semester, wedi’i ddethol o bortffolio a baratowyd gan aelodau staff o’u diddordebau ymchwil eu hunain. Bydd y gwaith yn gofyn yn bennaf am astudiaethau newydd lle bydd problem sydd ar flaen y gad ym maes Cemeg presennol yn cael ei datrys gan ddefnyddio ymchwil wreiddiol. Yn ogystal, bydd y modiwl yn gofyn i bob myfyriwr wneud arolwg llenyddiaeth manwl, a pharatoi adroddiad prosiect drafft a therfynol yn ogystal â chyflwyniad, a fydd yn cael ei arholi ar lafar. 

On completion of the module a student should be able to

  • Egluro’ cemeg sy'n sail i'r prosiect a ddewiswyd i gynulleidfa arbenigol neu leyg. 

 

  • Cynnal arbrofion a/neu efelychiadau ar lefel ymchwil yn unol â chyfarwyddyd goruchwyliwr academaidd. 

 

  • Dyfeisio arbrofion a/neu efelychiadau, eu cynnal a dadansoddi eu canlyniad naill ai yn y labordy neu ar gyfrifiadur. 

 

  • Gweithio'n ddiogel ac yn effeithlon ar dasgau lefel ymchwil, gan gynnwys nodi a meintioli risgiau a chwblhau'r holl hyfforddiant a gweithdrefnau diogelwch generig a phrosiect-benodol. 

 

  • Lledaenu canlyniadau ar ffurf adroddiad ac ar lafar a'u hamddiffyn wrth gael eu cwestiynu.  

 

  • Ymchwilio i'r llenyddiaeth i hyrwyddo nodau ymchwil a dylunio protocolau arbrofol. 

 

  • Disgrifio'n fanwl ar ffurf ysgrifenedig a llafar gemeg y testun a ddewiswyd, gan gynnwys gwybodaeth gefndir o'r llenyddiaeth a chanlyniadau newydd. 

 

  • Gweithio'n annibynnol pryd bynnag y bo modd.  

 

How the module will be delivered

Ymchwiliad annibynnol, mewn labordai ymchwil ac yn y llyfrgell, wedi'i oruchwylio gan aelod o'r staff academaidd a/neu ei enwebai o'r grŵp ymchwil. Bydd gofyn i fyfyrwyr gynhyrchu darnau o waith ysgrifenedig yn rheolaidd ar gyfer adborth ffurfiannol neu grynodol drwy gydol y prosiect.  

Skills that will be practised and developed

Sgiliau sy’n benodol i gemeg: 

 

Ar ôl cwblhau’r modiwl bydd y myfyriwr yn gallu: 

 

  • Cynllunio a chynnal ymchwiliad gwreiddiol mewn testun o unrhyw ran o gemeg ymarferol neu ddamcaniaethol. 

  • Dewis llenyddiaeth ffynhonnell a'i gosod yng nghyd-destun y prosiect, gydag asesiad beirniadol o'r gwaith blaenorol. 

  • Cofnodi nodiadau gwaith mewn modd priodol, gan gyfeirio at risg a pherygl lle bo'n berthnasol. 

  • Cynllunio a llunio adroddiad manwl mewn fformat safonol ar bob agwedd o'r prosiect; 

  • Cyflwyno darlith am y gwaith ac ateb cwestiynau mewn arholiad llafar. 

 

  

Sgiliau cyflogadwyedd:     

   

Cyflwynir y modiwl hwn ac mae'n cyd-fynd â'r Rhinweddau Graddedigion Prifysgol canlynol:   

 

  • Cyfrannu’n gadarnhaol ac yn effeithiol wrth weithio mewn tîm, ac yn gwneud gwahaniaeth o’r dechrau 

  • Arddangos brwdfrydedd, a’r gallu i ysgogi eu hunain a dylanwadu’n gadarnhaol ar eraill trwy gyfrifoldebau a gytunwyd arnynt mewn cyfarfod. 

  • Dangos parch at swyddogaethau pobl eraill a chydnabod cyfyngiadau eu sgiliau/profiad eu hunain. 

  • Gwrando ar eraill ac ystyried eu safbwyntiau. 

  • Cyfathrebu syniadau cymhleth yn effeithiol i gynulleidfaoedd amrywiol. 

  • Cyfrannu at drafodaethau, trafod a chyflwyno’n effeithiol. 

  • Ystyried eu cyfrifoldebau moesegol, cymdeithasol ac amgylcheddol personol a phroffesiynol 

  • Arddangos gonestrwydd, dibynadwyedd a gallu personol a phroffesiynol. 

  • Cofio am Argyfwng yr Hinsawdd a Nodau Datblygu Cynaliadwy’r Cenhedloedd Unedig 

  • Nodi, diffinio a dadansoddi materion a syniadau cymhleth, gan arfer barn feirniadol wrth werthuso ffynonellau gwybodaeth. 

  • Arddangos chwilfrydedd deallusol a cheisio meithrin gwybodaeth a dealltwriaeth. 

  • Ymchwilio i broblemau a chynnig datrysiadau effeithiol, myfyrio a dysgu o lwyddiannau a methiannau. 

  • Creu syniadau gwreiddiol a chymhwyso ffordd greadigol, llawn dychymyg a dyfeisgar o feddwl wrth ymateb i anghenion a phroblemau a nodwyd. 

  • Cymryd yr awenau wrth weithredu ar eu syniadau eu hunain a syniadau eraill, cydbwyso’r risgiau a’r canlyniadau posib a gwneud i bethau ddigwydd. 

  • Bod yn hyderus wrth fynd ar drywydd entrepreneuriaeth fel llwybr gyrfa amlwg a gwerth chweil. 

  • Deall sefydliadau, eu rhanddeiliaid a'u heffaith ar yr economi 

  • Mynd ati’n bwrpasol i fyfyrio ar eu hastudiaethau, eu cyflawniadau a’u hunaniaeth 

  • Arddangos gwytnwch, hyblygrwydd a chreadigrwydd i ddelio â heriau, a bod yn agored i newid. 

  • Adnabod a chyfleu eu sgiliau, eu gwybodaeth a’u dealltwriaeth eu hunain yn hyderus ac mewn amrywiaeth o gyd-destunau. 

  • Ystyried syniadau, cyfleoedd a thechnolegau newydd, gan ddatblygu gwybodaeth a phrofiad i wneud penderfyniadau gwybodus am eu dyfodol eu hunain. 

  • Gosod nodau uchelgeisiol ar gyfer datblygiad personol a phroffesiynol parhaus, cynllunio’n effeithiol ac ymroi i ddysgu gydol oes. 

Nodweddion Graddedig - Asesiad:   

 

Traethawd estynedig 40% 

  • Cyfathrebu syniadau cymhleth yn effeithiol i gynulleidfaoedd amrywiol. 

  • Cyfrannu at drafodaethau, trafod a chyflwyno’n effeithiol. 

  • Nodi, diffinio a dadansoddi materion a syniadau cymhleth, gan arfer barn feirniadol wrth werthuso ffynonellau gwybodaeth. 

  • Arddangos chwilfrydedd deallusol a cheisio meithrin gwybodaeth a dealltwriaeth. 

  • Ymchwilio i broblemau a chynnig datrysiadau effeithiol, myfyrio a dysgu o lwyddiannau a methiannau. 

  • Creu syniadau gwreiddiol a chymhwyso ffordd greadigol, llawn dychymyg a dyfeisgar o feddwl wrth ymateb i anghenion a phroblemau a nodwyd. 

  • Cymryd yr awenau wrth weithredu ar eu syniadau eu hunain a syniadau eraill, cydbwyso’r risgiau a’r canlyniadau posib a gwneud i bethau ddigwydd. 

  • Arddangos gwytnwch, hyblygrwydd a chreadigrwydd i ddelio â heriau, a bod yn agored i newid. 

  • Adnabod a chyfleu eu sgiliau, eu gwybodaeth a’u dealltwriaeth eu hunain yn hyderus ac mewn amrywiaeth o gyd-destunau. 

 

Asesiad ar sail gwaith ymarferol 15% 

  • Cyfrannu’n gadarnhaol ac yn effeithiol wrth weithio mewn tîm, ac yn gwneud gwahaniaeth o’r dechrau 

  • Ystyried eu cyfrifoldebau moesegol, cymdeithasol ac amgylcheddol personol a phroffesiynol 

  • Arddangos gonestrwydd, dibynadwyedd a gallu personol a phroffesiynol. 

  • Nodi, diffinio a dadansoddi materion a syniadau cymhleth, gan arfer barn feirniadol wrth werthuso ffynonellau gwybodaeth. 

  • Arddangos chwilfrydedd deallusol a cheisio meithrin gwybodaeth a dealltwriaeth. 

  • Ymchwilio i broblemau a chynnig datrysiadau effeithiol, myfyrio a dysgu o lwyddiannau a methiannau. 

  • Creu syniadau gwreiddiol a chymhwyso ffordd greadigol, llawn dychymyg a dyfeisgar o feddwl wrth ymateb i anghenion a phroblemau a nodwyd. 

  • Cymryd yr awenau wrth weithredu ar eu syniadau eu hunain a syniadau eraill, cydbwyso’r risgiau a’r canlyniadau posib a gwneud i bethau ddigwydd. 

  • Arddangos gwytnwch, hyblygrwydd a chreadigrwydd i ddelio â heriau, a bod yn agored i newid. 

 

Cyflwyniad 20% 

  • Cyfathrebu syniadau cymhleth yn effeithiol i gynulleidfaoedd amrywiol. 

  • Cyfrannu at drafodaethau, trafod a chyflwyno’n effeithiol. 

  • Ystyried eu cyfrifoldebau moesegol, cymdeithasol ac amgylcheddol personol a phroffesiynol 

  • Arddangos gonestrwydd, dibynadwyedd a gallu personol a phroffesiynol. 

  • Nodi, diffinio a dadansoddi materion a syniadau cymhleth, gan arfer barn feirniadol wrth werthuso ffynonellau gwybodaeth. 

  • Arddangos chwilfrydedd deallusol a cheisio meithrin gwybodaeth a dealltwriaeth. 

  • Ymchwilio i broblemau a chynnig datrysiadau effeithiol, myfyrio a dysgu o lwyddiannau a methiannau. 

  • Creu syniadau gwreiddiol a chymhwyso ffordd greadigol, llawn dychymyg a dyfeisgar o feddwl wrth ymateb i anghenion a phroblemau a nodwyd. 

  • Cymryd yr awenau wrth weithredu ar eu syniadau eu hunain a syniadau eraill, cydbwyso’r risgiau a’r canlyniadau posib a gwneud i bethau ddigwydd. 

  • Adnabod a chyfleu eu sgiliau, eu gwybodaeth a’u dealltwriaeth eu hunain yn hyderus ac mewn amrywiaeth o gyd-destunau. 

 

Asesiad Llafar/Clywedol 20% 

  • Gwrando ar eraill ac ystyried eu safbwyntiau. 

  • Cyfathrebu syniadau cymhleth yn effeithiol i gynulleidfaoedd amrywiol. 

  • Cyfrannu at drafodaethau, trafod a chyflwyno’n effeithiol. 

  • Ystyried eu cyfrifoldebau moesegol, cymdeithasol ac amgylcheddol personol a phroffesiynol 

  • Arddangos gonestrwydd, dibynadwyedd a gallu personol a phroffesiynol. 

  • Nodi, diffinio a dadansoddi materion a syniadau cymhleth, gan arfer barn feirniadol wrth werthuso ffynonellau gwybodaeth. 

  • Arddangos chwilfrydedd deallusol a cheisio meithrin gwybodaeth a dealltwriaeth. 

  • Ymchwilio i broblemau a chynnig datrysiadau effeithiol, myfyrio a dysgu o lwyddiannau a methiannau. 

  • Creu syniadau gwreiddiol a chymhwyso ffordd greadigol, llawn dychymyg a dyfeisgar o feddwl wrth ymateb i anghenion a phroblemau a nodwyd. 

  • Arddangos gwytnwch, hyblygrwydd a chreadigrwydd i ddelio â heriau, a bod yn agored i newid. 

  • Adnabod a chyfleu eu sgiliau, eu gwybodaeth a’u dealltwriaeth eu hunain yn hyderus ac mewn amrywiaeth o gyd-destunau. 

Traethawd estynedig 5% 

  • Cyfathrebu syniadau cymhleth yn effeithiol i gynulleidfaoedd amrywiol. 

  • Cyfrannu at drafodaethau, trafod a chyflwyno’n effeithiol. 

  • Nodi, diffinio a dadansoddi materion a syniadau cymhleth, gan arfer barn feirniadol wrth werthuso ffynonellau gwybodaeth. 

  • Arddangos chwilfrydedd deallusol a cheisio meithrin gwybodaeth a dealltwriaeth. 

  • Ymchwilio i broblemau a chynnig datrysiadau effeithiol, myfyrio a dysgu o lwyddiannau a methiannau. 

  • Creu syniadau gwreiddiol a chymhwyso ffordd greadigol, llawn dychymyg a dyfeisgar o feddwl wrth ymateb i anghenion a phroblemau a nodwyd. 

  • Cymryd yr awenau wrth weithredu ar eu syniadau eu hunain a syniadau eraill, cydbwyso’r risgiau a’r canlyniadau posib a gwneud i bethau ddigwydd. 

  • Arddangos gwytnwch, hyblygrwydd a chreadigrwydd i ddelio â heriau, a bod yn agored i newid. 

  • Adnabod a chyfleu eu sgiliau, eu gwybodaeth a’u dealltwriaeth eu hunain yn hyderus ac mewn amrywiaeth o gyd-destunau. 

Nodau Datblygu Cynaliadwy:      

 

Nid yw'r modiwl hwn yn cyd-fynd ag unrhyw un o'r Nodau Datblygu Cynaliadwy, ond mae ei bynciau yn sail i bob un.   

How the module will be assessed

Asesir y modiwl ar sail perfformiad yn y labordy, adroddiad ysgrifenedig, cyflwyniad llafar ac arholiad llafar (viva voce). 

Assessment Breakdown

Type % Title Duration(hrs)
Dissertation 40 Adroddiad Ysgrifenedig N/A
Practical-Based Assessment 20 Cyfraniad deallusol a/neu ymarferol N/A
Presentation 20 Cyflwyniad Llafar N/A
Oral/Aural Assessment 20 Arholiad Llafar N/A

Syllabus content

Mae'r modiwl hwn yn cynnwys un prosiect ymchwil dan oruchwyliaeth dros ddau semester, mewn unrhyw faes cemeg addas. Bydd y gwaith yn cynnwys astudiaethau newydd, arolwg llenyddiaeth, a pharatoi adroddiad prosiect a chyflwyniad, a fydd yn cael eu harchwilio ar lafar. Bydd pynciau fel arfer yn cynnwys gwaith labordy ymarferol, ond mae prosiectau gyda chydran ddamcaniaethol fawr a/neu seiliedig ar ddata hefyd yn bosibl, mewn meysydd priodol. 

 


CH7401: One Semester Project for Exchange Students

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH7401
External Subject Code 100417
Number of Credits 60
Level L7
Language of Delivery English
Module Leader Dr Athanasia Dervisi
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module is only available to exchange students.  A student taking this module will gain experience of original research, and have the opportunity to put into safe practice the previous training in techniques and methods of chemistry, and to produce a dissertation to a professional standard including review of appropriate literature.

On completion of the module a student should be able to

  1. describe in detail the chemistry of the chosen topic, including background information from the literature and new results;
  2. explain the chemistry underlying the chosen project.

How the module will be delivered

The student will undertake a project in a research laboratory under the supervision of a member of academic staff.  The results will be presented in a written report.

Skills that will be practised and developed

Intellectual skills

On completion of the module the student will be able to show a detailed and advanced mastery of a specific topic at the research frontier level.

Chemistry–specific skills

On completion of the module the student will be able to:

  1. plan and carry out an original investigation in a topic from any part of practical or theoretical chemistry;
  2. select source literature and place it within the context of the project, with critical assessment of preceding work;
  3. record all working notes in an appropriate manner, with reference to risk and hazard where applicable;
  4. plan and compose a detailed report in standard format on all aspects of the project.

Transferable skills

On completion of the module the student will be able to present and defend a case following detailed study.

How the module will be assessed

Assessment will be based both on performance in the laboratory and the quality of the written report.

Assessment Breakdown

Type % Title Duration(hrs)
Dissertation 100 ONE SEMESTER PROJECT FOR EXCHANGE STUDENTS N/A

Syllabus content

This module consists of one supervised research project spread over a single semester, in any suitable area of chemistry. The work will include new studies, a literature survey, and preparation of a project report.

Topics will normally involve practical laboratory work, but projects with a large theoretical component are also possible, in appropriate areas.


CH7401: One Semester Project for Exchange Students

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH7401
External Subject Code 100417
Number of Credits 60
Level L7
Language of Delivery English
Module Leader Dr Athanasia Dervisi
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module is only available to exchange students.  A student taking this module will gain experience of original research, and have the opportunity to put into safe practice the previous training in techniques and methods of chemistry, and to produce a dissertation to a professional standard including review of appropriate literature.

On completion of the module a student should be able to

  1. describe in detail the chemistry of the chosen topic, including background information from the literature and new results;
  2. explain the chemistry underlying the chosen project.

How the module will be delivered

The student will undertake a project in a research laboratory under the supervision of a member of academic staff.  The results will be presented in a written report.

Skills that will be practised and developed

Intellectual skills

On completion of the module the student will be able to show a detailed and advanced mastery of a specific topic at the research frontier level.

Chemistry–specific skills

On completion of the module the student will be able to:

  1. plan and carry out an original investigation in a topic from any part of practical or theoretical chemistry;
  2. select source literature and place it within the context of the project, with critical assessment of preceding work;
  3. record all working notes in an appropriate manner, with reference to risk and hazard where applicable;
  4. plan and compose a detailed report in standard format on all aspects of the project.

Transferable skills

On completion of the module the student will be able to present and defend a case following detailed study.

How the module will be assessed

Assessment will be based both on performance in the laboratory and the quality of the written report.

Assessment Breakdown

Type % Title Duration(hrs)
Dissertation 100 ONE SEMESTER PROJECT FOR EXCHANGE STUDENTS N/A

Syllabus content

This module consists of one supervised research project spread over a single semester, in any suitable area of chemistry. The work will include new studies, a literature survey, and preparation of a project report.

Topics will normally involve practical laboratory work, but projects with a large theoretical component are also possible, in appropriate areas.


CH8401: Long Project for Exchange Students

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8401
External Subject Code 100417
Number of Credits 120
Level L7
Language of Delivery English
Module Leader Dr Athanasia Dervisi
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module is only available to exchange students.  A student taking this module will gain experience of original research, and have the opportunity to put into safe practice the previous training in techniques and methods of chemistry, and to produce a dissertation to a professional standard including review of appropriate literature.

On completion of the module a student should be able to

a) describe in detail the chemistry of the chosen topic, including background information from the literature and new results;

b) explain the chemistry underlying the chosen project.

How the module will be delivered

The student will undertake a project in a research laboratory under the supervision of a member of academic staff.  The results will be presented in a written report.

Skills that will be practised and developed

Intellectual skills

The student will be able to show a detailed and advanced mastery of a specific topic at the research frontier level.

Chemistry –specific skills

The student will be able to:

a) plan and carry out an original investigation in a topic from any part of practical or theoretical chemistry;

b) select source literature and place it within the context of the project, with critical assessment of preceding work;

c) record all working notes in an appropriate manner, with reference to risk and hazard where applicable;

d) plan and compose a detailed report in standard format on all aspects of the project.

Transferable skills

The student will be able to present and defend a case following detailed study.

How the module will be assessed

Assessment will be based both on performance in the laboratory and the quality of the written report.

Assessment Breakdown

Type % Title Duration(hrs)
Dissertation 100 LONG PROJECT FOR EXCHANGE STUDENTS N/A

Syllabus content

This module consists of one supervised research project spread over a full academic year, in any suitable area of chemistry. The work will include new studies, a literature survey, and preparation of a project report. Topics will normally involve practical laboratory work, but projects with a large theoretical component are also possible, in appropriate areas.


CH8402: Frontiers in Ligand Design and Coordination Chemistry (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8402
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Benjamin Ward
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module will focus on the structure and design of ligands in the development of functional metal complexes.  Three areas will be covered, representing a cross section of pertinent problems in this area, these will be a) the development of catalysts based upon s and f block metals; b) the study of ligand dynamics and their influence on the structure and activity of metal complexes; and c) the stoichiometric and catalytic reactions of p-block elements.  The module will cover the synthesis of targeted ligand precursors, the coordination chemistry of these ligands, and their influence on specific types of reactivity.  Attention will be given to the analysis of structure-activity relationships.

On completion of the module a student should be able to

Knowledge

  • Show an awareness of the electronic properties of the s, p, d, and f block metals.
  • Show an awareness of how ligand structure influences the structure of metal complexes.
  • Appreciate the reactivity of metal complexes, and how this can be influenced by changes in the supporting ligands.
  • Identify structure-activity relationships in coordination complexes, particularly focussing on ligand structure and coordination geometry vs. reactivity.

Understanding

  • Relate the electronic structure of metals to the observed reactivity of metal complexes.
  • Understand the properties of ligands, and how design features can be used to control the properties of metal complexes.
  • Understand the dynamic nature of many metal complexes, and relate this to observed reactivity patterns.

How the module will be delivered

This module will be delivered in 10 two-hour lectures, supplemented by 4 1-hour class tutorials, and consists of three distinct blocks, each covering a different aspect of advanced ligand design and coordination chemistry. Each block will consist of lectures supported by an assessed piece of coursework.  The three blocks will mirror the three sections described above: (a) the development of catalysts based upon s and f block metals; (b) the study of ligand dynamics and their influence on the structure and activity of metal complexes; and (c) the stoichiometric and catalytic reactions of p-block elements .

Skills that will be practised and developed

Ability to analyse and review the details of ligand design and coordination chemistry, and relate these concepts to physical and chemical properties.

How the module will be assessed

The module is summatively assessed via in course assessments.

There is no examination for this module.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Frontiers in Ligand Design and Coordination Chemistry (Study Abroad) N/A

Syllabus content

The applications of ligand design and coordination chemistry to a range of areas, including catalysis and bioinorganic chemistry, with an emphasis on the ability of controlling the properties and reactivity of metal complexes by ligand design.

The properties of d0metals in polymerisation catalysis

A detailed mechanistic understanding of the properties and reactivity of d0metal alkyl and alkyl cations will be discussed.  These complexes have most widely studied in the context of alkene polymerisation, and this type of reactivity will be used to exemplify the reactivity of d0complexes.  The level of detail moves on from that covered in Year 3, encompassing the catalyst structures required for the production of stereospecific polymers.  This area will also cover the use of lanthanides in polymerisation catalysis, as well as the polymerisation of cyclic esters, commonly used as biodegradable polymers.

Heterofunctionalisation catalysis

The role of d0metal complexes as catalysts for a range of organic transformations will be discussed, with particular focus on hydroamination, hydrogenation, hydrosilylation, hydrophosphination, and hydroboration.  A particular focus will be given to looking at the mechanisms of these reactions, for which there are less reaction steps possible (e.g. oxidative addition is precluded).

The applications of alkaline earth metals in catalysis

The advent of the alkaline earth metals, particularly Mg and Ca, for catalytic processes will be discussed, including their role in hydroamination, hydrosilylation, and hydrogenation catalysis.  The scope and limitations, as well as catalytic reaction mechanisms will be covered.

N-heterocyclic carbenes

- Introduction to N-Heterocyclic Carbenes (NHC) as ligands and their complexes with transition metals, providing knowledge of the routes to their synthesis as well as on their structure, reactivity and electronic/steric properties. The scope and advantages of metal NHC compounds and their application in catalysis.

Cyclometalated compounds

- Cyclometalated metal complexes (with C,N, C,N,N, and C,N,C ligands) with emphasis on the synthesis and reactivity, as well as on ligand design to fine tune their chemico-physical properties. Examples of Au(III) cyclometalated complexes synthesis and applications.

p-Block organometallics

Introduction to p-block organometallics, including structure and reactivity

Introduction to frustrated Lewis pairs (FLPs), and their role in catalysis


CH8403: Bio-imaging Applications of Coordination Chemistry (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8403
External Subject Code 100948
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Professor Simon Pope
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

The module consists of three main topics associated with the application of inorganic coordination compounds to biological and biomedical imaging: optical, magnetic resonance and radioimaging will be covered. The module will provide a brief technical background to each of the imaging modalities and then focus upon the use and application of metal coordination compounds in each. Aspects of synthesis, spectroscopic characterisation and molecular design will be described, and the ability to rationalise the relationship between complex structure and function (including the biological context) will be a fundamental focus.

On completion of the module a student should be able to

Knowledge

  • know the fundamental concepts and principles that underpin optical imaging, magnetic resonance imaging and radioimaging via SPECT and PET techniques.
  • understand the concepts that drive the ligand design and choice of metal ion for a given imaging application
  • know the synthetic pathways to the target species, and spectroscopic techniques required for elucidating the key physical properties of the imaging agents.
  • know the key methodologies for ensuring biocompatibility and complex stability in vitro and in vivo.

Understanding

  • understand how spectroscopic techniques can be used to underpin the design of imaging agents.
  • understand the pros and cons of different classes of metal complex species to a given imaging technique
  • appreciate the biological implications and restrictions associated with the different imaging modalities.

How the module will be delivered

This module will be delivered in 10 two-hour lectures, supplemented by 4 1-hour class tutorials, and consists of three distinct blocks, each covering a different imaging modality and the type of metal complex that can be applied to it.  A series of lectures will introduce these topics. Three workshops will be used to introduce students to the state-of-the-art via the primary literature.

Skills that will be practised and developed

Ability to rationalise ligand structure, metal complex physical properties, biocompatibility and subsequent applications to a given imaging technique.

The engagement with the primary literature and an ability to scientifically critique published material will be developed.

How the module will be assessed

The module is summatively assessed via in course assessments.

There is no examination for this module.

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Bio-imaging Applications of Coordination Chemistry (Study Abroad) N/A

Syllabus content

Optical imaging using Luminescence

Background on confocal fluorescence microscopy for cellular imaging

Background on photophysics – Stokes shift, Jablonski diagram, time resolved vs steady state measurements,  quenching pathways, types of emission, tuning emission through ligand design.

Types of TM-based lumophore including descriptions of ligand design, photophysics and applications to imaging and biocompatibility

                  - d6 Ru(II), Os(II), Re(I), Ir(III)

                  - d8 Pt(II)

                  - d10 Au(I)

Types of Ln(III)-based lumophore including descriptions of ligand design, photophysics and applications to imaging and biocompatibility

                  - visible emission using Eu(III) and Tb(III)

                  - near-IR emission using Nd(III) and Yb(III)

Magnetic Resonance Imaging and Contrast Agents

Background on magnetic resonance imaging. The history and the basic principles of the experiment.

Background on the fundamental properties and design of T1 and T2 contrast agents.

Types of complexes used for T1 contrast- lanthanide, transition metal and organic molecules.

Types of complexes used for T2 contrast- lanthanides and transition metal clusters.

Using CEST and PARACEST for imaging.

Assessing new contrast agents –solubility, stability and the NMRD.

Dual mode imaging and the theranostic approach.

Gamma Radio-Imaging via SPECT and PET

Background to gamma imaging – physical basis of the techniques, data capture and imaging
Single Photon Emission Tomography (SPECT)
Positron Emission Tomography (PET) -
general properties of PET/SPECT isotopes, half lives, imaging resolution, biological matching

Background to functional imaging vs. structural imaging –
organ perfusion imaging, inflammation imaging, bone imaging (SPECT)
biologically active PET probes (FDG, F-DOPA, etc.)

Ligand design for SPECT and PET isotopes and metal complexes –
Tc complexes for SPECT
Ga, Cu, Zr, Y complexes in PET


CH8404: Asymmetric Synthesis of Pharmaceuticals and Natural Products (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8404
External Subject Code 100423
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Professor Thomas Wirth
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module consists of a range of examples exposing the students to sophisticated methods in stereoselective synthesis. Building on previous knowledge, advanced methods for stereocontrol in total synthesis, preparation of enantiomerically pure drug molecules, development of stereoselective rearrangement processes as well as the introduction of various enabling technologies will be the main focus of this module. Throughout, the ability to extract stereochemically relevant information from complex syntheses will be a major focus.

On completion of the module a student should be able to

Knowledge

  • Appreciate the range of synthetic methods available to prepare enantiomerically pure molecules.
  • Know the strategies and reagents required to generate and implement new stereochemical elements within target-oriented syntheses.
  • Identify key problems in both small-scale academic synthesis and large scale industrial synthesis of stereochemically pure compounds.
  • Identify different reaction technology equipment and summarise the key criteria to consider before using it.

Understanding

  • Understand the principles and strategies of stereoselective alkene functionalization.
  • Understand main principles in the use of enabling technologies and related industrial issues together with application to target molecules.
  • Recognize where organocatalysis can be applied in synthesis and which strategies in this area are available.
  • Explain when alternative tools and techniques may offer significant benefit to a desired reaction outcome.

How the module will be delivered

This module will be delivered in 10 two-hour lectures, supplemented by 4 1-hour class tutorials, and consists of three blocks, each covering a different aspect of asymmetric synthesis. An initial set of lectures will be used to revise already known principles and reactions and introduce novel methods that can be used to tackle certain problems in asymmetric synthesis together with their theoretical background and any strengths or weaknesses associated with them. These will be followed by three units in which such methods are applied to chemical problems.

Skills that will be practised and developed

Ability to analyse stereochemical problems and provide synthetic solutions.

How the module will be assessed

The module is summatively assessed via in course assessments.

There is no examination for this module.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Asymmetric Synthesis of Pharmaceuticals and Natural Products (Study Abroad) N/A

Syllabus content

Alkene Functionalisations

Introduction to advanced asymmetric synthesis. Stereoselective functionalisations of double bonds: Briefly revising Sharpless AE and ADH, Jacobsen (year 3), then introduction of other electrophilic reagents including selenium- and iodine-based compounds.  Applications in total synthesis and the synthesis of bioactive compounds will be discussed.

Enabling Tools for Organic Synthesis

As synthesis moves in to the modern era so too does the way in which chemists can conduct chemistry. This part of the course introduces the technical considerations needed for using existing and futuristic synthesis tools such as microwave reactors, photochemical reactors, electrochemistry and continuous flow chemistry. Important factors are being considered when conducting reactions using these methods, there will also be a strong focus on the types of synthetic chemistry suited to these modes.

Organocatalysis

Organocatalysis is defined as the use of a sub-stoichiometric amount of an organic molecule to accelerate the rate of a chemical reaction. This part will serve as an introduction to the diverse and exciting field of organocatalysis and will specifically cover: a historical perspective; benefits and limitations; catalyst synthesis; covalent and non-covalent organocatalytic activation modes; selectivity (regio-, diastereo- and enantiocontrol); applications within industry; applications towards the synthesis of biologically active compounds.


CH8405: Advanced Techniques in Biophysical Chemistry (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8405
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Niklaas Buurma
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

In this module, the application of physical techniques and artificially modified biomolecules to problems in structure and mechanism in biological chemistry research will be discussed. Students will appreciate what information can be gained from each technique and learn how to plan experiments and interpret the resulting data for probing structure, dynamics and reactivity.

On completion of the module a student should be able to

  • decide which experimental techniques are most appropriate for solving problems in biological chemistry;
  • understand how chemical, physical and biological techniques can be combined to address complex problems;
  • understand how biophysical techniques are used to study interactions between biomacromolecules, and between small molecules and biomacromolecules;
  • decide which (bio)physical techniques are appropriate for the study of interactions.
  • interpret the results of biophysical interaction studies;
  • discuss previous knowledge of photo-chemistry in a biological context;
  • understand how to use NMR and X-ray crystallography to get structural information for protein-protein interactions and protein-small molecule interactions;
  • have an insight in enzyme catalytic mechanisms based on enzyme structure.  

How the module will be delivered

This module will be delivered in 10 two-hour lectures, supplemented by 3 1-hour class tutorials, covering different aspects of organic and biological chemistry. A series of lectures will introduce the methods that can be used to tackle problems in this area, analytical techniques involved and the theoretical background as well as any strengths or weaknesses associated with them. This will be further broadened and deepened in the class tutorials.

Skills that will be practised and developed

Solution of problems by application of knowledge from different areas of chemistry, physics and biology.

How the module will be assessed

The module is summatively assessed via in course assessments.

There is no examination for this module.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Coursework N/A

Syllabus content

Spectroscopic techniques

Principles of UV/Vis, fluorescence, FRET, circular dichroism, vibrational circular dichroism spectroscopies as used in biophysical studies. The use of temperature-dependent spectroscopy to obtain thermodynamic data. Data acquisition and interpretation.

Solution calorimetric techniques

DSC and ITC. Data acquisition and interpretation.

Other techniques

Further biophysical techniques, including surface plasmon resonance (SPR); SPR instrumentation; SPR methods for determining equilibrium constants and kinetics; biolayer interferometry; SwitchSENSE; Mass spectrometry for study of biomolecules; electrochemical techniques and other modern techniques in biophysical chemistry.

Data analysis

Applications of these techniques to the study of biomolecular structure and interactions, including data analysis and estimation of error margins.

Application of 1D and multi-dimensional Nuclear Magnetic Resonance (NMR) for molecular interactions; Introduction to X-ray crystallography for acquiring atomic details of biomolecular structures; computation based on reliable structure information. Introduction to protein engineering; rationale for engineering proteins and introduction to protein engineering strategies; mutagenesis, protein libraries. 


CH8406: Molecular Modelling (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8406
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader DR Alberto Roldan Martinez
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module exposes students to the range of computational methods that can be applied to diverse chemical problems, from the structure and property of molecules to chemical thermodynamics, kinetics and reactivity. Methods for describing molecules, ranging from quantum chemical and molecular orbital methods for relatively small molecules to atomistic simulation of larger, more complex systems will be discussed. Throughout, the ability to extract chemically relevant properties from molecular modelling experiments will be a major focus.

On completion of the module a student should be able to

Knowledge

  • Appreciate the range of modelling methods available to tackle chemical problems.
  • Know the fundamentals of theories underpinning such methods.
  • Identify the key results obtained from calculations, and interpret these with regard to the physics/chemistry of the problem.

Understanding

  • Realise the strengths and limitations of various modelling methods for tackling chemical problems.
  • Understand the scope of particular methods, appreciate the errors involved and how to estimate and control such errors
  • Appreciate the trade-off between accuracy and computational resources.

How the module will be delivered

This module consists of four distinct blocks, each covering a different aspect of molecular modelling, delivered through five hours of lectures, and supplemented by class tutorials.

Skills that will be practised and developed

Ability to analyse and critically assess various approaches to computational simulation of chemical systems.

How the module will be assessed

The module is summatively assessed via in course assessments.

There is no examination for this module.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Molecular Modelling (Study Abroad) N/A

Syllabus content

A selection of applications across the spectrum of molecular modelling techniques, including the structure and properties of molecules and their potential energy surfaces, chemical energetics and thermodynamics, chemical reactivity and kinetics.

Molecular Electronic Structure

Correlated wavefunction and density-functional methods; electromagnetic properties; excited states; intermolecular interactions

Model Force Fields

Parameterised forms for bonded interactions; functional forms and methods for parameterisation; specifics for non-bonded interactions: charges, multipoles, Leonard-Jones & Buckingham potentials; application to organic and inorganic systems

Electronic Structure for Catalysis Applications

Hartree-Fock and Density-Functional theories for periodic solids; molecular and dissociative adsorption

Molecular Dynamics

Fundamentals of Molecular Dynamics; Born-Oppenheimer, Ehrenfest and Car-Parrinello dynamics; time propagation algorithms; periodic boundary conditions; radial distribution functions; thermodynamics of ensembles; examples of applications


CH8407: Advanced Materials (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8407
External Subject Code 100225
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Jonathan Bartley
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

The module aims to develop an understanding of the synthesis, characterization, simulation and applications of specific advanced materials in the modern chemical environment.

The course will cover modelling nanoparticles; colloid systems in industry and healthcare; heterogeneous catalysis with nanoparticles and bulk catalysts; and the synthesis and characterisation of these advanced materials.

On completion of the module a student should be able to

Knowing(these are things that all students will need to be able to do to pass the module):

  • Demonstrate awareness of different methods for synthesising advanced materials
  • Describe different techniques that can be for advanced materials characterization
  • Explain the influence of the structure on the properties of different advanced materials.
  • Understand the benefits and limitations of molecular modelling in probing material properties.
  • Demonstrate some appreciation for the important factors in formulating a new colloidal product and understand the functional limitations on materials used for drug delivery compared to alternative applications.

Acting(Performance in this area will enable students to achieve more than a basic pass):

  • Identify the key methods for the characterisation of advanced, including their applicability and limitations.
  • Understand and predict key properties of materials based on characterisation data.
  • Predict the effect different external factors will have on the structure and properties of advanced materials.

Being(Performance in this area will enable students to achieve more than a basic pass):

  • Link synthetic methods for advanced materials with their properties and activity for different processes.
  • Link desired observables with appropriate simulation methods.
  • Design characterization plans to determine key performance indicators for advanced materials.

How the module will be delivered

The module will consist of 10 × 2 hour lectures that will introduce the topics laid out in the syllabus that address the “Knowing” Learning Outcomes, while examples presented will show students how they may also demonstrate their achievement of the “Acting” and “Being” Learning Outcomes.

Students will be expected to supplement these lectures with independent research of texts, specialist reviews and peer-reviewed literature.

Tutorials (4 × 1 h) will be used to supplement the lecture material, go through worked examples, enhance problem-solving skills and develop the skills necessary to achieve the “Acting” and “Being” Learning Outcomes.

Skills that will be practised and developed

Chemistry-specific skills will be focused on applying ideas from fundamental physical and inorganic chemistry to understand how these can be applied to advanced materials for different applications. Students will develop a detailed understanding of how properties of materials can be controlled by tuning the synthesis procedure and how advanced characterisation methods can be used to help derive structure activity relationships. The module will also involve a large element of problem solving.

How the module will be assessed

The module is summatively assessed via in course assessments.

There is no examination for this module.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Advanced Materials (Study Abroad) N/A

Syllabus content

Colloidal systems: This part of the module will focus on structure-activity relationships in colloidal systems relevant to important applications in industry and healthcare, plus advanced methods used for their characterisation. Topics will include: advanced characterisation techniques, structure activity relationships in surfactants, polymer solutions, polymer particle interactions, polymer surfactant interactions and a case study – colloids in drug delivery.

Synthesis of heterogeneous catalysts: This part of the module will focus on the synthesis of catalysts and supports. It will include case studies of different catalyst systems. Different synthesis methods will be introduced such as sol-gel, hard and soft templating, antisolvent precipitation to prepare bulk catalysts and supports. Methods of preparing supported catalysts will also be covered including impregnation, deposition-precipitation and the use of pre-formed sols.

Modelling nanoparticles:This part of the module will focus on nanoparticles and how they can be modelled. It will include mono and bimetallic nanoparticles, nanoparticle-support interactions and how these modify the structural and electronic properties and how the environment can change the functionality of nanoparticles.


CH8408: Modern Catalysis (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8408
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Jennifer Edwards
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module consists of lectures and class tutorials that will develop many of the fundamental concepts in catalysis, and show how they can be applied to some of the major challenges in chemistry, including:

·       Environmental protection (through control of NOx, VOC and CO emissions)

·       Using catalysis to generate clean energy

·       Upgrading low-value and waste products

·       Fine and bulk chemical synthesis

·       Replacing supply-limited precious metal catalysts by less rare materials

The content will draw strongly on the complementary fields of nanoscience, solid-state chemistry, surface science, organometallic chemistry, and synthetic organic chemistry. 

On completion of the module a student should be able to

Relate catalyst structure to surface reactivity

·       Explain relevant theory such as electronic metal-support interaction

·       Compose hypotheses and propose detailed reaction mechanisms for homogeneous reactions

·       Demonstrate understanding of bimetallic catalysis systems, and how these affect substrate conversion and product selectivity

Appreciate and understand how ligand design enables better chemo-, regio- and stereo-control in homogeneous catalysis

·       Propose original catalytic solutions to real-world problems

More specifically:

Knowing (these are things that all students will need to be able to do to pass the module):

  • Demonstrate awareness of the application of heterogeneous and homogeneous catalysts for a range of modern processes and reactions.
  • Demonstrate understanding of structure, function and activity of heterogeneous and homogeneous catalysts.
  • Describe the fundamental principles and mechanisms of various catalysts.

Acting (Performance in this area will enable students to achieve more than a basic pass):

  • Evaluate experimental data from catalyst performance and relate this to catalyst characteristics.
  • Propose mechanisms for a range of catalysed transformations covering a wide range of chemistry.
  • Propose key catalyst characteristics to effectively catalyse a wide range of reactions that are important for modern processes.

Being (Performance in this area will enable students to achieve more than a basic pass):

Critically assess data relating to catalyst performance, communicating key concepts and characteristics, and suggest potential catalysts for unseen reactions.

How the module will be delivered

This module consists of 10 lectures (each 2 hours) and 4 interactive sessions (1 hour class tutorials).  The lectures will cover the 4 main themes that are listed under Syllabus Content.  The class tutorials will comprise analysis of research publications.   

Skills that will be practised and developed

The skills acquired will prepare the student for the application of the principles of ‘green catalysis’.

  • Catalyst evaluation: Assessing the advantages and limitations of emergent catalysts and catalytic technologies
  • Catalyst design: Selecting the components of high-performance catalysts that can be regenerated and recycled
  • Process optimisation: Proposing strategies for optimising the performance (rate, selectivity, durability) of catalysts and catalytic reactors

How the module will be assessed

The module is summatively assessed via in course assessments.

There is no examination for this module.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Coursework N/A

Syllabus content

The syllabus will cover 3 main themes:

(i)           Catalysts for environmental protection -  This module concentrates mainly on treatment of emissions from stationary sources, as well as water purification. There is particular emphasis on the fundamental aspects of the chemistry, in respect to catalyst preparation, microscopic, macroscopic and surface structure, and probing the catalytic mechanism.

(ii)        Homogeneous catalysis in the 21stcentury  - This part of the module considers how established homogeneous catalytic systems can be improved in terms of both cost and environmental impact.  In particular, application of the principles of ‘green catalysis’ will be emphasised with regard to the nature of the catalyst, the chemical process itself and greener alternatives to established materials.

(iii)        Grand challenges for catalysis –Fundamental catalyst studies can be translated to technology and process improvements, where lab scale discoveries are exploited on a commercial level, improving process efficiency using less toxic catalyst materials. Examples of novel production routes of fine chemicals, and processing of waste streams to value added chemicals will be illustrated. 


CH8409: Applications of Advanced Spectroscopic Methods (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8409
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader PROFESSOR Philip Davies
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

Spectroscopy is one of the central pillars of chemistry, providing essential information on the reactants, products and critically, intermediates, involved in every chemical reaction studied. In this module, we discuss applications of spectroscopy across a very broad range of fields with a particular emphasis on interfacial and atmospheric processes where Cardiff has particular expertise. The module describes some aspects of the cutting edge of research being undertaken in the School and discusses the unique tools being exploited at Cardiff to investigate these areas.

On completion of the module a student should be able to

  • use properties of electronic potential energy surfaces to explain dynamical outcomes of chemical reactions
  • be able to describe and understand basic scenarios in which the Born-Oppenheimer approximation breaks down, and how that effects reaction outcomes
  • be able to detail several experimental techniques for probing gas phase spectroscopy and reaction dynamics
  • appreciate the fundamental principles of interface spectroscopy & microscopy
  • describe surface structures and discuss methods of determining them
  • interpret data acquired from a range of surface sensitive spectroscopies and microscopies
  • understand how synchrotron radiation is generated and the significance of using tuneable wavelengths of light from the synchrotron.
  • understand various enhanced mechanisms of Raman spectroscopy applied to adsorbates.
  • know the surface selection rules and their uses.

How the module will be delivered

The module will be delivered in 10 two-hour lectures, supplemented by 4 one-hour class tutorials.

Skills that will be practised and developed

Please see Learning Outcomes.

How the module will be assessed

The module is summatively assessed via in course assessments.

There is no examination for this module.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Applications of Advanced Spectroscopic Methods (Study Abroad) N/A

Syllabus content

Gas phase spectroscopy and dynamics

  • Potential energy surfaces governing the outcomes of ground state reaction dynamics
    • To and from the Polanyi rules
  • Potential energy surfaces governing the outcomes of excited state dynamics
    • Beyond the Born-Oppenheimer approximation
  • Spectroscopic probes for gas phase chemical reaction dynamics
    • The advantages offered by the simplicity of gas phase measurements
    • Advanced spectroscopic techniques for state-selective chemical detection
    • Increasing the complexity to reduce the uncertainty
  • Extensions to the solution phase and beyond…
    • Can we extend what we know into more complex environments?

Fundamental principles of interface spectroscopy and microscopy

  • Fundamental limitations of spectroscopy at interfaces and methods of addressing them
  • Advanced experimental methods for exploring interface science
  • Surface structures and conventions for describing them
  • Experimental methods for exploring surface structure
  • The unique advantages and applications of synchrotron light sources for probing interface environments
  • EXAFS, and real-time “operando” measurements applied to metallic and oxide catalytic surfaces in situ

Vibrational spectroscopy at surfaces and interfaces

  • Fundamentals of Raman spectroscopy, including its advantages for probing heterogeneous catalytic processes
  • Enhanced Raman Spectroscopy for overcoming conventional limitations, including resonance-enhanced, surface-enhanced and tip-enhanced Raman spectroscopies
  • Case studies of Raman spectroscopy in heterogeneous catalysis: collection of in situ data; mechanistic studies; restructuring phenomena; probing aqueous phase chemistry

CH8410: Advanced Magnetic Resonance Spectroscopy: Principles and Applications (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8410
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Professor Kenneth Harris
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

Magnetic resonance techniques, including NMR and EPR, are extremely powerful tools for investigating the structure and dynamics of molecules. This module offers the student the opportunity to study the underlying physical principles of NMR and EPR in the solid state, and the surrounding magnetic interactions that determine the appearance of the experimental spectra. Coverage of conventional principles in magnetic resonance, showing how the resonance frequency of a nucleus (or electron) is affected not only by the applied field but also by the electronic environment and surrounding nuclei, will be presented to the students. A more advanced EPR technique called ENDOR, where EPR and NMR transitions are simultaneously monitored, will also be introduced in both liquid phase and solid phase conditions. Particular emphasis will be devoted to the analysis of NMR and EPR spectra in the solid state. The anisotropic interactions responsible for the broad and more complex spectral line shapes experienced in the solid state (compared to the isotropic profiles experienced in the liquid state) will be treated using a series of examples. The advanced methodology of angular selective ENDOR, used to analyse and extract structural information, for paramagnetic species in frozen solution, will also be treated.

On completion of the module a student should be able to

  • Understand the origin of the Zeeman interaction;
  • Understand the importance of spin angular momentum and the spin magnetic moment in magnetic resonance spectroscopy;
  • describe the behaviour of nuclear and electron spins in an applied magnetic field;
  • understand the role of spin angular momentum as the foundation stone in NMR and EPR;
  • describe the importance of magnetic interactions, namely spin-spin coupling, as a vital source of information; 
  • understand the nature of anisotropic interactions in the solid state, and how they dictate the shape of the spectra;
  • understand how various magnetic interactions including electron Zeeman interactions, zero field splitting, hyperfine interactions, nuclear Zeeman interactions, and quadrupole interactions, can also be extracted from the EPR spectrum;
  • know how dynamic, as well as structural, information can be accessed in the solid state, and understand the importance of the time-frame of the NMR techniques in dynamic studies;
  • discuss the approaches taken to record NMR spectra in solid state;
  • describe how the ENDOR technique is performed and the role of saturation and relaxation phenomena in acquiring ENDOR signals with optimal amplitudes;
  • describe how the angular selective ENDOR methodology is applied to study paramagnetic systems in the solid state.

How the module will be delivered

The module will be delivered in 10 two-hour lectures, supplemented by 4 one-hour class tutorials.

Skills that will be practised and developed

On completion of the module a student should be able to:

  • link formal equations to observed NMR/EPR spectra;
  • interpret experimental observations in terms of the molecular and structural properties of the system;
  • select appropriate techniques for determination of structure in solution or solid state for a range of chemical situations;
  • assess the advantages/disadvantages of the different techniques for each particular purpose and chemical problem;
  • appreciate the steps involved in the analysis of modern magnetic resonance experiments;
  • understand how NMR/EPR may be used to study problems of general chemical interest;
  • use qualitative arguments to develop a theoretical description of magnetic resonance phenomena;
  • use quantitative measurements to verify or disprove theoretical models.

How the module will be assessed

The module is summatively assessed via in course assessments.

There is no examination for this module.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Coursework N/A

Syllabus content

Foundations in Solid State NMR: This part of the course will provide an introduction to solid-state NMR spectroscopy, focusing initially on relevant theoretical background and experimental techniques. The discussion of background theory will highlight the significant differences between solid-state NMR and liquid-state NMR, focusing on the main anisotropic NMR interactions that are important in the solid state. The discussion of experimental strategies will then focus on the techniques for recording: (a) broad-line solid-state NMR spectra (in which the anisotropic NMR interactions are studied), and (b) high-resolution solid-state NMR spectra (in which the aim is to record narrow-line spectra that resemble those recorded in liquid-state NMR). The course will then build upon these foundations by discussing the applications of solid-state NMR to investigate structural and dynamic properties of solids, highlighting the scope and limitations of different types of solid-state NMR technique. Several recent examples of the application of solid-state NMR to solve problems in solid-state and materials chemistry will be presented. Students attending the course will emerge with an appreciation of the types of problem that can be tackled successfully by solid-state NMR, and the particular NMR technique (or combination of techniques) is most suitable for investigating each type of problem.

Foundations of liquid and solid state EPR & ENDOR: The basic principles underlying the EPR technique will be covered, including coverage of the form of the spin Hamiltonian for systems in the solid state. This will initially be treated for the liquid phase, before considering the more complex case of the solid state. Anisotropy of the g and A hyperfine tensors, and the role of symmetry as manifested in the g/A frame will then be presented to the students. The theory and applications of angular selective ENDOR, based on the angular dependency of the EPR spectra, will also be covered in the lectures. Examination of the profiles of EPR spectra in the solid state will then be covered. The lectures will then cover the theory of ENDOR, with particular emphasis on the saturation and relaxation pathways important in this technique. The role of angular selection as a means of determining structural information for paramagnetic centres in the solid state will then be given. Examples of systems with low g anisotropy (no hyperfine interaction) leading to powder ENDOR patterns, and subsequently axial g anisotropy and axial hyperfine, leading so ‘single crystal-like’ ENDOR patterns will then be investigated. The students will then appreciate the experimental approaches taken to obtain EPR and ENDOR spectra of paramagnetic centres in the solid state (primarily in frozen solution) and the general methodologies subsequently involved in the analysis and understanding of the experimental data. Numerous examples of how to interpret solid state EPR 7 ENDOR spectra will be covered during the course.


CH8411: Catalytic Materials for Green Chemistry (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8411
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Professor David Willock
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module will cover the synthesis, characterisation and simulation of the catalytic materials that find applications in the Green Chemistry and energy sectors. The current trend in chemistry to reduce our dependence on fossil sources of carbon for chemicals and fuels is giving rise to a whole new set of challenges in catalysis. We will survey the synthesis of catalysts and applications that these materials are put to. We will also show how careful characterisation and simulation approaches can give a structure/activity level of understanding in heterogeneous catalysis that helps to design and optimise catalytic materials.

On completion of the module a student should be able to

  • Understand the range of methodologies used in synthesising heterogeneous catalytic material including pre- and post-treatments applied to enhance/control catalytic activity.
  • Describe the control of surface features, material phases and compositions that can be achieved using a variety of synthetic approaches.
  • Understand the characterisation methods used for heterogeneous catalytic materials and discuss the information which each method provides.
  • Discuss the mechanisms of sample catalytic target reactions in the Green Chemistry and Energy sectors.
  • Describe in situ measurements that are used to scope out elementary surface reactions during catalysis.
  • Appreciate the use of computer simulation in establishing the electronic and geometric features of active sites on catalyst surfaces.
  • Understand how computer simulation is applied to map out reaction energetics for key steps in heterogeneously catalysed reactions.

How the module will be delivered

The module will be delivered through 10 x 2 hr lectures and 4 class tutorials leading into self-learning activities to enhance student understanding and skills in the areas covered by the module. Students will have the opportunity to explore these aspects through independent learning activities alongside the lectures presenting the required material.

Skills that will be practised and developed

Students will have the opportunity to develop their critical analysis and problem solving skills, dealing with data from a variety of methods to come to a rounded understanding of catalyst structure, materials properties and mode of operation in key catalytic processes.

How the module will be assessed

The module is summatively assessed via in course assessments.

There is no examination for this module.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Catalytic Materials for Green Chemistry (Study Abroad) N/A

Syllabus content

The module will cover the synthesis of catalytic materials for Green Chemistry and energy sectors. The characterisation methods used to measure properties such as the solid phases present, the effective surface area of catalysts and spectroscopic inspection of working catalysts will be addressed. The overall aim of the module is to demonstrate how materials characterisation and simulation can help to inform a mechanistic understanding of heterogeneous catalysis for key reactions.


CH8412: Supramolecular Chemistry (Study Abroad)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8412
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Louis Luk
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

The objective of this module is to reach an understanding of the nature and magnitude of the intermolecular dynamic interactions that provide the driving force for the association between molecules and/or ions induced by covalent and non-covalent bonding interactions in solution, solid-state and at interfaces. The current trend in modern chemistry is to go beyond the classical molecular approach to provide a deeper understanding of molecular organization at different scales in both artificial and biological systems. We will survey the most important engineering approaches toward the preparation of complex matter along with the main characterization techniques and exploitation approaches for engineering technological-relevant applications. By surfing through the most important examples, we will also show how careful programming of the simple molecular components one can reach higher level of complexity with such a structure/activity level of understanding to design functional supramolecular architectures featuring applications in organic chemistry, chemical biology, materials science and nanotechnology.

Once the basic principles have been covered, the course will move on to a discussion of principles and examples of solution, surface and solid-state self-assembled molecular species and extended molecular frameworks. Specifically, molecular cages, surface self-assembled networks and metal-organic frameworks will be covered, with examples of their sensing and storage applications, before moving on to increasingly complex molecular logic-gates and molecular machines that begin to mimic biological systems in their function.

Additionally, this course will go through the concepts of how nature exploits supramolecular chemistry to perform crucial biological events, such as nucleic acid- and protein- depending function and ion transport. Important biotechnological applications based on self-assembled peptides/DNA, streptavidin:biotin and antibody will be discussed.

On completion of the module a student should be able to

  • Discuss the role of supramolecular chemistry in organic chemistry, chemical biology, materials science and nanotechnology.
  • Explain non-covalent interactions, molecular recognition and self-assembly.
  • Write short descriptions of some of the applications of supramolecular chemistry, including in dynamic covalent chemistry, materials chemistry (e.g. soft materials), biological systems and the construction of nanoscale entities.
  • Describe in situ measurements that are used to study molecular interactions.
  • Display extended comprehension of key chemical concepts and an in-depth understanding of complex matter.
  • Adapt and apply fundamental methodology to the solution of unfamiliar problems and to technology relevant applications.
  • Demonstrate critical awareness of advances at the forefront of the chemical science discipline interfacing with different disciplines.

How the module will be delivered

The module will be delivered through 10 x 2 hr lectures and 4 hours workshops (two hours including presentation of a research idea, one hour of discussion and one hour for feedback) leading into self-learning activities to enhance student understanding and skills in the areas covered by the module. Students will have the opportunity to explore these aspects through independent learning activities (writing a scientific proposition along) alongside the lectures presenting the required material.

Skills that will be practised and developed

Students will have the opportunity to develop their critical analysis and problem solving skills, dealing with data from a variety of methods to come to a rounded understanding of catalyst structure, materials properties and mode of operation in key catalytic processes. 

How the module will be assessed

The module is summatively assessed via in course assessments.

There is no examination for this module.

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Supramolecular Chemistry (Study Abroad) N/A

Syllabus content

The module will cover the principles of molecular recognition:

Basic concepts in self-assembly and self-organization, thermodynamics and kinetics of host-guest processes along with the main characterization techniques (Lectures 1&2); complexation of neutral molecules in aqueous solution and their technological applications - sensors and drug delivery (Lecture 3); non-covalent interactions involving aromatic rings (Lecture 4); hydrogen-, halogen- and chalcogen-bonding interactions (Lecture 5&6); dynamic covalent bonds (Lecture 7); supramolecular polymers (Lecture 8); Template effects & molecular self-assembly approach towards nanostructures in solutions (including molecular cages and inorganic nanotubes), on surfaces (2D networks and topology considerations) and in the solid-state (Lectures 9&10); basic concepts of crystal engineering; MOFs (and COFs), gas storage, separation and sensing applications (Lecture 11-12); applications of molecular recognition in logic gates, including medical diagnostics, colorimetric and luminescent sensors (Lecture 13); molecular machines, from simple catenanes and rotaxanes to more complex multi-station multi-stimuli responsive supramolecular systems, finishing with conceptual and functional links with biological supramolecular chemistry (Lecture 14); basic concepts of molecular recognition in biology, including cell architecture, biomolecular interactions, structure of essential building units, lipids, DNA/RNA, protein, sugar (Lectures 15&16); natural Ion Channels, including peptide-based ion change, cation/anion complexation, cross-membrane ion channel (Lectures 17&18); biotechnological applications (e.g. artificial enzyme design, live cell imaging, cellular import/drug delivery) based on the concepts of supramolecular chemistry; particular examples include DNA-directed synthesis, streptavidin:biotin, self-assembled peptides and antibodies technology and anti-virus drug development (Lectures 19&20).


CH8481: Project for Exchange Students

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8481
External Subject Code 100417
Number of Credits 80
Level L7
Language of Delivery English
Module Leader Dr Paul Newman
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module consists of a supervised research project spread over two semesters, selected from a portfolio prepared by members of staff from their own research interests. The work will largely require new studies in which a problem at the leading edge of a current area of Chemistry will be tackled using original research. In addition, the module will require all students to carry out a detailed literature survey, and preparation of a draft and final project report as well as a presentation, which will be examined orally. 

On completion of the module a student should be able to

  • Communicate effectively, using a range of methods, articulating academic ideas and technical arguments in manners appropriate to both specialist and non-specialist audiences. 

 

  • Devise experiments and/or simulations, carry them out and analyse the outcome. 

 

  • Independently evaluate results and disseminate in both report and oral format, defend them under questioning.  

 

  • Demonstrate initiative and independence by taking responsibility for structuring and time-managing a research task. 

 

  • Research and study creatively and independently, applying advanced knowledge and skills to unfamiliar topics or contexts. 

How the module will be delivered

Independent investigation, both in research laboratories and library, supervised by a member of academic staff and/or their nominee from research group. You will be required to regularly produce pieces of written work for formative or summative feedback throughout the duration of the project.  

Skills that will be practised and developed

 

Chemistry-Specific Skills: 

 

On completion of the module, you will be able to: 

 

  • Plan and carry out an original investigation in a topic from any part of practical or theoretical chemistry. 

  • Select source literature and place it within the context of the project, with critical assessment of preceding work. 

  • Record working notes in an appropriate manner, with reference to risk and hazard where applicable. 

  • Plan and compose a detailed report in standard format on all aspects of the project; 

  • Present a lecture about the work and answer questions in oral examination. 

 

  

Employability skills:     

   

This module is delivered and aligns with the following University Graduate Attributes:   

 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Demonstrate enthusiasm and the ability to motivate themselves and positively influence others in meeting agreed responsibilities. 

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience. 

  • Listen to and take account of the views of others. 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate and present with impact. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path. 

  • Understanding organisations, their stakeholders and their impact on the economy 

  • Actively reflect on own studies achievements and self-identity 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

Graduate Attributes – Assessment:   

 

Dissertation 40% 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate and present with impact. 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Practical based assessment 20% 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

 

Presentation 20% 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate and present with impact. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Oral/aural Assessment 20% 

  • Listen to and take account of the views of others. 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate and present with impact. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Sustainable Development Goals:      

 

This module does not align with any of the Sustainable Development Goals, but its topics do underpin all.   

How the module will be assessed

The module will be assessed on the basis of performance in the laboratory, a written report, an oral presentation and an oral (viva voce) examination. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Given the weighting of this module, if you fail, you will have to repeat the year.  

 

Assessment Breakdown

Type % Title Duration(hrs)
Dissertation 40 Written Report N/A
Practical-Based Assessment 20 Intellectual and/or Practical Contribution N/A
Presentation 20 Oral Presentation N/A
Oral/Aural Assessment 20 Oral Examination N/A

Syllabus content

This module consists of one supervised research project spread over two semesters, in any suitable area of chemistry. The work will include new studies, a literature survey, and preparation of a project report and a presentation, which will be examined orally. Topics will normally involve practical laboratory work, but projects with a large theoretical and/or data-based component are also possible, in appropriate areas. 


CH8482: Metals in Medicine and Bioimaging (for Exchange students)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8482
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Professor Simon Pope
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

 

This module will cover modern aspects of inorganic coordination chemistry, including the design of d- and f-block coordination complexes and metal-based nanoparticles for application in bioimaging techniques and medicine. It will set out the ways in which ligands and complexes can be designed to achieve desired properties and functionality. It will examine a range of bioimaging techniques (including, magnetic resonance imaging, radioimaging and luminescence microscopy), including their underlying principles, and show how different metal complexes can be designed for these applications, including for the visualisation of cellular function and diagnosis of disease. Aspects of synthesis, spectroscopic characterisation and molecular design will be described, as will ways to rationalise the relationship between structure and function. This will lead to the description and case study analysis of responsive probes, bimodal systems, biological targeting, and theranostic agents.  

On completion of the module a student should be able to

 

Describe synthetic chemistry pathways to target ligands, complexes and nanoparticles. 

Interpret spectroscopic and physical data and appreciate how variations in structure relates to function in different biological contexts.     

Appreciate the design of metal-based species for biological environments, and how this influences the design of supporting ligands and nanoparticles. 

Describe the fundamental concepts and principles, and the advantages and disadvantages, associated with different bioimaging techniques, especially in the context of visualisation of cellular functions and diagnosis of diseases. 

Critically analyse literature-based examples thereby demonstrating a knowledge of the design criteria of metal-based agents for biological applications 

 

How the module will be delivered

Content will be delivered primarily using lectures.  

Formative workshops will be used to discuss case studies from the literature, enhance and assess problem-solving skills related to the critical analysis of data, and demonstrate application of knowledge. 

 

Skills that will be practised and developed

 

Academic Skills:  

  • Interpret complex scientific information and relate to properties of different classes of coordination complexes 

  • Understanding what kind of information (including visualisation of cellular processes; disease states) is provided by different bioimaging techniques  

  • Develop effective skills focussed upon reviewing primary literature and extracting relevant    information  

 

Chemistry-Specific Skills: 

  • You will appreciate ligand structure and bonding in metal complexes and be able to apply concepts of targeted molecular design to more complicated scenarios;  

  • You will learn how to analyse datasets and to formulate an explanation for observations of physical properties, thereby developing a level of understanding closer to situations expected in graduate-level employment.   

  • You will refine your problem-solving skills in situations that require them to synthesise a coherent argument or explanation using knowledge/data from a number of different sources.  

 

Employability skills:     

   

This module is delivered and aligns with the following University Graduate Attributes:   

 

  • Contribute to discussions, negotiate and present with impact. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Actively reflect on own studies achievements and self-identity 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future.  

  

   

Graduate Attributes – Assessment:     

   

Written assessment             100% 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information, including primary literature. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change 

  • Identify and articulate own skills, knowledge and understanding confidently 

Sustainable Development Goals:       

 

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

  • Goal 3. Ensure healthy lives and promote well-being for all at all ages 

  • Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

How the module will be assessed

  

Summative coursework assessment (100%) workshop is a take-home assessment that requires engagement and analysis of the lecture material and associated primary literature. This will assess your ability to use electronic databases, locate relevant scientific information and critically review  literature. This will assess your knowledge of molecular design and a deep understanding of the physical parameters that dictate the biological potential and application of your chosen system.   

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

  

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Written Assignments N/A

Syllabus content

Fundamental aspects of coordination chemistry in medicine: solubility products, formation constants,ligand pKa, coordination complexes of d- and f-block metal ions; organometallic and cyclometalated complexes; understanding biocompatibility, targeted design, bioconjugation and responsive systems 

 

Ligand design: chelating, multidentate and macrocyclic variants, siderophores, bioconjugation 

 

Optical imaging using Luminescence   

Background on confocal fluorescence microscopy for cellular imaging  

Background on photophysics – Stokes shift, Jablonski diagrams, time resolved vs steady state measurements, quenching pathways, types of emission, tuning emission through ligand design.  

Types of transition metal-based luminophore. Types of lanthanide(III)-based compounds. Upconverting nanoparticles.  

 

Magnetic Resonance Imaging and Contrast Agents  

Background on magnetic resonance imaging. Background on the fundamental properties and design of T1 and T2 contrast agents. Pulse sequences. Types of complexes used for T1 and T2 contrast. Assessing new contrast agents –solubility, stability and the NMRD. Molecular agents and nanoparticle systems. 

  

Gamma Radio-Imaging via SPECT and PET   

Background to gamma imaging – physical basis of the techniques, data capture and imaging.  
Single Photon Emission Tomography (SPECT). Positron Emission Tomography (PET). 
General properties of PET/SPECT isotopes, half-lives, imaging resolution, biological matching.  

Background to functional imaging vs. structural imaging. Types of molecular agents. 
 

Multimodal Imaging agents 

Understanding design principles and critical analysis of applications 


CH8482: Metals in Medicine and Bioimaging (for Exchange students)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8482
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Professor Simon Pope
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

 

This module will cover modern aspects of inorganic coordination chemistry, including the design of d- and f-block coordination complexes and metal-based nanoparticles for application in bioimaging techniques and medicine. It will set out the ways in which ligands and complexes can be designed to achieve desired properties and functionality. It will examine a range of bioimaging techniques (including, magnetic resonance imaging, radioimaging and luminescence microscopy), including their underlying principles, and show how different metal complexes can be designed for these applications, including for the visualisation of cellular function and diagnosis of disease. Aspects of synthesis, spectroscopic characterisation and molecular design will be described, as will ways to rationalise the relationship between structure and function. This will lead to the description and case study analysis of responsive probes, bimodal systems, biological targeting, and theranostic agents.  

On completion of the module a student should be able to

 

Describe synthetic chemistry pathways to target ligands, complexes and nanoparticles. 

Interpret spectroscopic and physical data and appreciate how variations in structure relates to function in different biological contexts.     

Appreciate the design of metal-based species for biological environments, and how this influences the design of supporting ligands and nanoparticles. 

Describe the fundamental concepts and principles, and the advantages and disadvantages, associated with different bioimaging techniques, especially in the context of visualisation of cellular functions and diagnosis of diseases. 

Critically analyse literature-based examples thereby demonstrating a knowledge of the design criteria of metal-based agents for biological applications 

 

How the module will be delivered

 

Content will be delivered primarily using lectures.  

Formative workshops will be used to discuss case studies from the literature, enhance and assess problem-solving skills related to the critical analysis of data, and demonstrate application of knowledge. 

 

 

 

 

 

Skills that will be practised and developed

 

Academic Skills:  

  • Interpret complex scientific information and relate to properties of different classes of coordination complexes 

  • Understanding what kind of information (including visualisation of cellular processes; disease states) is provided by different bioimaging techniques  

  • Develop effective skills focussed upon reviewing primary literature and extracting relevant    information  

 

Chemistry-Specific Skills: 

  • You will appreciate ligand structure and bonding in metal complexes and be able to apply concepts of targeted molecular design to more complicated scenarios;  

  • You will learn how to analyse datasets and to formulate an explanation for observations of physical properties, thereby developing a level of understanding closer to situations expected in graduate-level employment.   

  • You will refine your problem-solving skills in situations that require them to synthesise a coherent argument or explanation using knowledge/data from a number of different sources.  

 

Employability skills:     

   

This module is delivered and aligns with the following University Graduate Attributes:   

 

  • Contribute to discussions, negotiate and present with impact. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Actively reflect on own studies achievements and self-identity 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future.  

  

   

Graduate Attributes – Assessment:     

   

Written assessment             100% 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information, including primary literature. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change 

  • Identify and articulate own skills, knowledge and understanding confidently 

Sustainable Development Goals:       

 

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

  • Goal 3. Ensure healthy lives and promote well-being for all at all ages 

  • Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

How the module will be assessed

  

Summative coursework assessment (100%) workshop is a take-home assessment that requires engagement and analysis of the lecture material and associated primary literature. This will assess your ability to use electronic databases, locate relevant scientific information and critically review  literature. This will assess your knowledge of molecular design and a deep understanding of the physical parameters that dictate the biological potential and application of your chosen system.   

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

  

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Written Assignments N/A

Syllabus content

Fundamental aspects of coordination chemistry in medicine: solubility products, formation constants,ligand pKa, coordination complexes of d- and f-block metal ions; organometallic and cyclometalated complexes; understanding biocompatibility, targeted design, bioconjugation and responsive systems 

 

Ligand design: chelating, multidentate and macrocyclic variants, siderophores, bioconjugation 

 

Optical imaging using Luminescence   

Background on confocal fluorescence microscopy for cellular imaging  

Background on photophysics – Stokes shift, Jablonski diagrams, time resolved vs steady state measurements, quenching pathways, types of emission, tuning emission through ligand design.  

Types of transition metal-based luminophore. Types of lanthanide(III)-based compounds. Upconverting nanoparticles.  

 

Magnetic Resonance Imaging and Contrast Agents  

Background on magnetic resonance imaging. Background on the fundamental properties and design of T1 and T2 contrast agents. Pulse sequences. Types of complexes used for T1 and T2 contrast. Assessing new contrast agents –solubility, stability and the NMRD. Molecular agents and nanoparticle systems. 

  

Gamma Radio-Imaging via SPECT and PET   

Background to gamma imaging – physical basis of the techniques, data capture and imaging.  
Single Photon Emission Tomography (SPECT). Positron Emission Tomography (PET). 
General properties of PET/SPECT isotopes, half-lives, imaging resolution, biological matching.  

Background to functional imaging vs. structural imaging. Types of molecular agents. 
 

Multimodal Imaging agents 

Understanding design principles and critical analysis of applications 


CH8483: Molecules for Health and Life (for Exchange students)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8483
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Professor Thomas Wirth
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module will describe modern aspects of organic, biological and medicinal chemistry. Building on the required previous modules CH4302 and CH4303, it will introduce advanced methods for control in the synthesis of target molecules. It will explain in detail how preparation of enantiomerically pure molecules is achieved, for example in pharmaceuticals, and describe development of stereoselective reactions as well as various enabling technologies such as electrochemistry, photochemistry, organo- and enzyme catalysis and flow synthesis including automation. It will set out how molecular synthesis can be targeted towards specific applications, such as medicinal chemistry or sustainability. It will also explain application of biophysical techniques to study interactions in biological and medicinal chemistry research, and methods for simulation of molecules of importance to life and health. Throughout, the ability to extract chemically relevant information from complex systems will be a major focus. 

On completion of the module a student should be able to

 

  • Appreciate the range of synthetic methods, strategies and reagents available to prepare challenging synthetic targets, including enantiomerically pure molecules.  

 

  • Explain the main principles in the use of enabling reaction technologies and related industrial issues together with application to target molecules. 

 

  • Identify the key inter- and intramolecular interactions that determine biomolecular structure and drug-receptor binding. 

 

  • Decide on technique(s) appropriate to study interactions between biomacromolecules and between biomacromolecules and small molecules.  

 

  • Appreciate molecular modelling and simulation methods suitable for studying problems in medicinal and biological chemistry. 

 

  • Interpret and critically assess the results from biophysical and computational techniques.  

 

How the module will be delivered

Content will be delivered through a combination of approaches, including lectures, pre-recorded content and problem-solving workshops. Contact time, in the form of lectures or problem-solving workshops, is 40 h across two semesters, equating to approximately two sessions per week. Support for learning will include informal ad hoc formative tests.  

  

Workshops and tutorials will be used to enhance and assess problem-solving skills related to the retrieval and analysis of data. 

 

Skills that will be practised and developed

 

Chemistry -Specific Skills: 

 

  • Development of detailed understanding of how molecular structures are related to specific usages, and how these structures can be formed through organic synthesis. 

 

  • Approaches to evaluate the success of molecules addressing targets of biological interest will be trained and the accompanying data analysis approaches will be developed. 

 

  • The module will also involve a large element of problem solving using both numerical and algebraic techniques, based around real examples of experimental and theoretical data. 

 

Employability skills:     

   

This module is delivered and aligns with the following University Graduate Attributes:   

 

Contribute to discussions, negotiate and present with impact. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Actively reflect on own studies achievements and self-identity 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future.  

  

   

Graduate Attributes – Assessment:     

   

  

Presentation                    100% 

  • Contribute to discussions, negotiate and present with impact. 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Sustainable Development Goals:       

    

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

  • Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture  

  • Goal 3. Ensure healthy lives and promote well-being for all at all ages 

  • Goal 7. Ensure access to affordable, reliable, sustainable and modern energy for all 

  • Goal 8. Promote sustained, inclusive and sustainable economic growth, full and productive employment and decent work for all 

  • Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

How the module will be assessed

 A single piece of coursework will allow you to demonstrate knowledge of key concepts and apply that knowledge to chemical problems. Marks will reflect the extent to which you have met the module learning outcomes shown above. 

 

 

Assessment Breakdown

Type % Title Duration(hrs)
Presentation 100 Presentation N/A

Syllabus content

Organic synthesis and stereoselective chemistry. Applications in total synthesis and the synthesis of bioactive compounds and labelled molecules.  

 

Enabling tools for organic synthesis: microwave reactors, photochemical reactors, electrochemistry and flow chemistry, radionuclide chemistry.  

 

Synthesis automation, machine learning and AI in synthesis and bioorganic chemistry. 

 

Molecular recognition in biology. Biomolecular interactions, structure of essential building units. Supramolecular chemistry in biotechnological applications. 

 

Biophysical techniques: key principles of spectroscopies used in biophysical studies. Calorimetry: DSC and ITC. Surface-based techniques in biophysical chemistry; electrochemical approaches to studying interactions. Data acquisition and interpretation, analysis and estimation of error margins. 

 

Supramolecular chemistry in biology: nucleic acid and protein as well as their applications, spanning form small molecule synthesis, artificial enzyme design and antibody-drug conjugate creation.  

 

Molecular modelling for molecules of life: parameterised methods, potential energy surfaces, forces, local and global optimisation, dynamics 


CH8484: Modern Materials (for Exchange Students)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8484
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Dr Alison Paul
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

  • The module aims to develop an understanding of the synthesis, formulation, characterisation, simulation of advanced materials relevant to the development of materials for modern world applications.  

  • It will set out how modern chemistry goes beyond the single molecule, analysing the driving forces for the association between molecules and/or ions that are induced by non-covalent bonding interactions in solution, solid-state and at interfaces. Relating these qualities to bulk material behaviour through the understanding of important structure – property relationships, the module will link fundamental principles to the informed design of modern materials, including consideration of potential commercial feasibility and reduction of environmental impact. 

  • It will describe materials such as nanoparticles, colloidal systems, crystalline and amorphous solids, and supramolecular architectures in 2- and 3-dimensions. The course will set out methods for determining and modelling their structural, dynamic, and electronic properties, including static, time-resolved and spatially resolved analyses. 

On completion of the module a student should be able to

 

  • Describe how different methods for synthesising and formulating advanced materials can impact on their performance in different applications.   

  • Evaluate and predict key properties of materials based on modelling and characterisation data.  

  • Analyse experimental/characterisation/modelling data for different advanced materials to probe the material properties and establish an understanding between structure, composition, and chemistry.  

  • Explain the importance of time-resolution and spatial-resolution in analytical measurements on modern materials and describe what additional information these methods provide in comparison to static techniques. 

  • Explain key concepts of molecular recognition in biology and apply these to the structure and function of biomaterials.  

  • Critically assess literature relating to advanced materials properties and applications. 

 

How the module will be delivered

  • Content will be delivered primarily via lectures (40 h across two semesters, equating to approximately two lectures per week). Lectures will include discussion activities, worked problems and informal ad hoc formative tests.  

  

  • Workshops and tutorials will be used to enhance and assess problem-solving skills related to the retrieval and analysis of data. 

Skills that will be practised and developed

 

Chemistry-Specific Skills:  

 

  • Applying ideas from fundamental chemistry to understand how properties of molecules, solids and surfaces are utilised in the design of modern materials with specific target properties. 

 

  • You will practise data interpretation skills, extending your skills to multi-component systems. 

 

  • You will develop a detailed understanding of how properties of molecules and materials are related to their electronic structure, and how these properties are related to observed behaviour and spectra.  

 

  • The module will also involve a large element of problem solving using both numerical and algebraic techniques, based around real examples in materials chemistry. 

 

Employability skills:     

   

This module is delivered and aligns with the following University Graduate Attributes:   

 

Contribute to discussions, negotiate and present with impact. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Actively reflect on own studies achievements and self-identity 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future.  

  

Graduate Attributes – Assessment:     

   

Written assessment:   

    

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Contribute to discussions, negotiate and present with impact. 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Sustainable Development Goals:       

    

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

  • Goal 8. Promote sustained, inclusive and sustainable economic growth, full and productive employment and decent work for all 

  • Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

  • Goal 11. Make cities and human settlements inclusive, safe, resilient and sustainable 

  • Goal 13. Take urgent action to combat climate change and its impacts 

How the module will be assessed

 

A written assessment will test your ability to demonstrate your knowledge and understanding of the syllabus content, and your ability to apply the techniques/concepts covered to unseen problems. A single piece of coursework will allow you to apply knowledge to chemical problems through critically assessment and evaluation of methods for the synthesis, characterisation and application of materials, thereby demonstrating knowledge and understanding of key concepts. Marks will reflect the extent to which you have met the module learning outcomes shown above. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Coursework N/A

Syllabus content

Self-assembly and self-organization in colloidal formulations of surfactants, polymers and particles. Structure activity relationships and interaction between components in formulations, including supporting case studies. Advanced methods for the characterisation of nanoscale structure and bulk properties. Applications in industry and healthcare. 

 

Thermodynamics and kinetics of host-guest processes of biomacromolecules. Non-covalent interactions in solid-state and solution. Dynamic covalent bonds & supramolecular polymers. Molecular machines.  

 

Experimental techniques and methods for nanoscale and ultrafast chemistry for supramolecular processes. 

 

Fundamental properties of advanced materials in technological applications. Properties and applications of semiconducting materials, and the impact of defects. Properties of interfaces and surfaces on geometric, energetic and electronic properties.  

 

Solid-state NMR spectroscopy. Theoretical background and experimental techniques. Anisotropic NMR interactions in solid materials. Techniques for recording broad-line and high-resolution solid-state NMR spectra. Applications of solid-state NMR to investigate structural and dynamic properties of solids. 

 

Simulation of materials. Atomistic and electronic structure methods. Calculation of static, dynamic and electronic properties of solids. Periodic density functional theory and forcefield approaches.  


CH8485: Catalysis and Interfaces for Sustainable Chemistry (for Exchange students)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8485
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Dr Jennifer Edwards
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module will cover the synthesis, characterisation and simulation of the catalytic materials that find applications in the development of sustainable chemicals production and energy sectors.  

 

The need to reduce our dependence on fossil sources of carbon for chemicals and fuels is giving rise to a whole new set of challenges in catalysis. The module will introduce pathways used to transform renewable resources into useful chemicals and emphasize how characterisation and simulation lead to understanding which helps to design and optimise catalytic materials.  

 

It will also address current issues in environmental chemistry, including use of catalysis to address clean air, water and energy generation. It will explain how fundamental properties of solids, surfaces and nanoparticles can be related to catalytic activity.  

 

You will develop critical analysis skills through study of literature case studies and quantitative approaches to defining how environmentally friendly a chemical process really is. 

On completion of the module a student should be able to

 

  • Appreciate the fundamental principles of structure, function and activity of heterogeneous catalysts in modern catalytic processes, Green Chemistry and energy sectors. 

  • Evaluate experimental data from catalysts performance experiments and relate this to physical and chemical information describing catalyst structure and then use this to propose a catalytic mechanism solution. 

  • Describe common structural features of heterogeneous catalysts and how these relate to activity. 

  • Appreciate the range of techniques that can be used to characterise catalyst and surface structures, and how these can be used to explain and predict activity. 

  • Describe in situ measurements that are used to scope out elementary surface reactions during catalysis. 

  • Explain the main computational chemistry approaches used in the simulation of catalytic materials and catalysed reactions. 

 

How the module will be delivered

  • Content will be delivered primarily using lectures (40 h across two semesters, equating to approximately two lectures per week). In addition, lectures will include worked problems and informal ad hoc formative tests.  

  • Workshops and tutorials will be used to enhance and assess problem-solving skills related to the retrieval and analysis of data. 

Skills that will be practised and developed

Chemistry-Specific Skills: 

 

  • Applying ideas of catalysis to appreciate how catalytic systems can be designed and interrogated using experimental and simulation techniques.  

  • You will develop a detailed understanding of how properties of materials are related to their catalytic activity, and how these properties can be controlled.  

  • The module will also involve a large element of problem solving using both numerical and algebraic techniques, based around real examples of theoretical methods. 

  • The module is centred in sustainable chemistry, and you will also acquire the vocabulary and analytical skills to exercise critical judgement regarding the contribution a particular catalytic process can make to improving the environment and reducing the impact of anthropogenic activity. 

 

Employability skills:     

   

This module is delivered and aligns with the following University Graduate Attributes:   

 

Contribute to discussions, negotiate and present with impact. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Actively reflect on own studies achievements and self-identity 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future.  

  

Graduate Attributes – Assessment:     

 

Written assessment                100% 

  • Contribute to discussions, negotiate and present with impact. 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Sustainable Development Goals:       

    

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

  • Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture  

  • Goal 3. Ensure healthy lives and promote well-being for all at all ages 

  • Goal 6. Ensure availability and sustainable management of water and sanitation for all 

  • Goal 7. Ensure access to affordable, reliable, sustainable and modern energy for all 

  • Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

  • Goal 12. Ensure sustainable consumption and production patterns 

How the module will be assessed

A single piece of coursework will allow you to demonstrate knowledge of key concepts and apply that knowledge to chemical problems. Marks will reflect the extent to which you have met the module learning outcomes shown above. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Written Assignments N/A

Syllabus content

 

The module will cover the synthesis of catalytic materials which can underpin sustainable chemicals and energy sectors. The principals of Green Chemistry will be reviewed with current literature examples of industrial processes that have been superseded by more sustainable chemistry. The characterisation methods used to measure properties such as the solid phases present, the effective surface area of catalysts and spectroscopic inspection of working catalysts will be addressed alongside high-resolution microscopy capable of giving atomic level images of catalytic materials. The main approaches to the computer simulation of catalytic materials will also be introduced, with examples that integrate with the theme of Sustainable Chemistry drawn from the literature. Reaction schemes will be presented and discussed based on calculated potential energy surfaces and the insights these given into the catalytic processes they represent. The overall aim of the module is to demonstrate how materials characterisation and simulation can help to inform a mechanistic understanding of heterogeneous catalysis using key reactions as exemplars.    

 


CH8486: Frontiers in inorganic chemistry (for Exchange students)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH8486
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Dr Benjamin Ward
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module will focus on the structure, influence, and design of ligands and compounds in the development of functional metal complexes and main-group compounds.  Four areas will be covered, representing a cross section of pertinent problems in this area, these will be a) metal complexes for catalytic polymerisation and depolymerisation; b) the study of N-heterocyclic carbene complexes and their catalytic chemistry; and c) the stoichiometric and catalytic reactions of frustrated Lewis pairs; d) advanced aspects of homogeneous catalysis for sustainable chemical synthesis.  The module will cover the synthesis of ligand precursors, coordination chemistry, including in cases where there is no electronic preference to coordination geometry, and homogeneous catalysis.  Attention will be given to the analysis of structure-activity relationships and the interpretation of catalytic data in terms of reaction mechanisms. The module highlights the use of inorganic chemistry for sustainable chemical processes and aligns with UN STGs 9, 11, 12, 13, 14, and 15. 

On completion of the module a student should be able to

 

  1. Formulate a catalytic reaction mechanism within unfamiliar operating parameters (e.g. catalyst and/or substrate structure). 

 

  1. Critically evaluate catalytic reaction data in terms of the likely reaction mechanism, substrate structure, and catalyst design; assess structure-reactivity effects of ligands and formulate reactivity patterns. 

 

  1. Design an appropriate synthetic strategy for ligands and complexes within provided constraints. 

 

  1. Choose appropriate analytical techniques to characterise chemical species and assess analytical data in terms of chemical structure. 

 

How the module will be delivered

The module will be delivered in 20 2-hour lectures and four 1-hour tutorials. 

The module consists of four distinct blocks, each covering a different aspect of advanced inorganic and coordination chemistry. The four blocks will mirror the three sections described above: (a) the production and chemical recycling of polymers, including traditional polyolefins and modern alternatives; (b) metal complexes bearing N-heterocyclic carbene ligands in catalysis for sustainable chemical synthesis; (c) the role of frustrated Lewis pairs in catalysis; and (d) modern aspects of coordination chemistry relating to catalysis. Each block will be followed by a tutorial in which problem-solving and analytical skills are practised. 

Skills that will be practised and developed

 

Chemistry-specific skills: 

 

  • Learn how to analyse complex datasets and to formulate an explanation for trends and observations of chemical reactivity patterns.  

  • Develop the ability to relate the fundamental properties of functional metal complexes to a modern understanding of sustainable chemistry. 

  • Learn how to construct a cost-benefit analysis of making chemical processes aligned to the UN Sustainable Development Goals.  

  • Develop problem-solving skills in situations that require them to synthesise a coherent argument or explanation using knowledge/data from several different sources, particularly relating to chemical processes involving metal complexes. 

 

Employability skills: 

 

This module is delivered and aligns with the following University Graduate Attributes:  

 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Actively reflect on own studies achievements and self-identity 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future.  

 

Graduate attributes – assessment: 

 

Written assessment (100%) 

 

  • Contribute to discussions, negotiate and present with impact. 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Sustainable development goals: 

 

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialisation and foster innovation. 

Goal 11. Make cities and human settlements inclusive, safe, resilient and sustainable. 

Goal 12. Ensure sustainable consumption and production patterns. 

Goal 13. Take urgent action to combat climate change and its impacts. 

Goal 14. Conserve and sustainably use the oceans, seas, and marine resources for sustainable development. 

Goal 15. Protect, restore and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse biodiversity loss. 

 

 

 

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Written Assignments N/A

Syllabus content

The applications of ligand design and coordination chemistry to a range of areas, including catalysis and p-block chemistry, with an emphasis on the ability of controlling the properties and reactivity of metal complexes by ligand design. 

The past and future of polymerisation catalysis 

A detailed mechanistic understanding of the properties and reactivity of d0 metal alkyl and alkyl cations will be discussed.  These complexes have most widely studied in the context of alkene polymerisation, and this type of reactivity will be used to exemplify the reactivity of d0 complexes.  The level of detail moves on from that covered in level 6, encompassing the catalyst structures required for the production of stereospecific polymers and the influence of agostic interactions to facilitate migratory insertion reactions.  This theme will be expanded to introduce the polymerisation of cyclic esters, commonly used as biodegradable polymers, and then ultimately to the forefront of polymerisation research where ring-opening co-polymerisation of CO2/epoxides and anhydrides/epoxides will be covered in detail. Approaches for depolymerisation catalysis by metal complexes will be covered. 

Heterofunctionalisation catalysis 

The role of d0metal complexes as catalysts for a range of organic transformations will be discussed, with particular focus on hydroamination, hydrogenation, hydrosilylation, and hydrophosphination.  A particular focus will be given to looking at the mechanisms of these reactions, for which there are less reaction steps possible (e.g. oxidative addition is precluded). This theme will be expanded to cover alkaline earth metals in catalysis, including their environmental benefits, their scope, and their limitations. 

Homogeneous catalysis in the 21st century 

This part of the module considers how established homogeneous catalytic systems can be improved in terms of both cost and environmental impact.  In particular, application of the principles of ‘green catalysis’ will be emphasised with regard to the nature of the catalyst, the chemical process itself and greener alternatives to established materials. The development of N-heterocyclic carbenes will be discussed, in relation to their synthesis, coordination chemistry, and catalytic applications. Comparisons will be drawn between NHC complexes and those bearing alternative ligands. 

p-Block organometallics 

Introduction to p-block organometallics, including structure and reactivity trends will be provided. This will lead to a detailed discussion of frustrated Lewis pairs (FLPs), and their role in catalysis. 


CH9401: Short Project for Exchange Students

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH9401
External Subject Code 100417
Number of Credits 30
Level L7
Language of Delivery English
Module Leader Dr Athanasia Dervisi
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module is only available to exchange students.  A student taking this module will gain experience of original research, and have the opportunity to put into safe practice the previous training in techniques and methods of chemistry, and to produce a dissertation to a professional standard including review of appropriate literature.

On completion of the module a student should be able to

a) describe in detail the chemistry of the chosen topic, including background information from the literature and new results;

b) explain the chemistry underlying the chosen project.

How the module will be delivered

The student will undertake a project in a research laboratory under the supervision of a member of academic staff.  The results will be presented in a written report.

Skills that will be practised and developed

Intellectual skills

The student will be able to show a detailed and advanced mastery of a specific topic at the research frontier level.

Chemistry –specific skills

The student will be able to:

a) plan and carry out an original investigation in a topic from any part of practical or theoretical chemistry;

b) select source literature and place it within the context of the project, with critical assessment of preceding work;

c) record all working notes in an appropriate manner, with reference to risk and hazard where applicable;

d) plan and compose a detailed report in standard format on all aspects of the project.

Transferable skills

The student will be able to present and defend a case following detailed study.

How the module will be assessed

Assessment will be based both on performance in the laboratory and the quality of the written report.

Assessment Breakdown

Type % Title Duration(hrs)
Dissertation 100 SHORT PROJECT FOR EXCHANGE STUDENTS N/A

Syllabus content

This module consists of one supervised research project spread over a single semester, in any suitable area of chemistry. The work will include new studies, a literature survey, and preparation of a project report. Topics will normally involve practical laboratory work, but projects with a large theoretical component are also possible, in appropriate areas.


CH9401: Short Project for Exchange Students

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CH9401
External Subject Code 100417
Number of Credits 30
Level L7
Language of Delivery English
Module Leader Dr Athanasia Dervisi
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module is only available to exchange students.  A student taking this module will gain experience of original research, and have the opportunity to put into safe practice the previous training in techniques and methods of chemistry, and to produce a dissertation to a professional standard including review of appropriate literature.

On completion of the module a student should be able to

a) describe in detail the chemistry of the chosen topic, including background information from the literature and new results;

b) explain the chemistry underlying the chosen project.

How the module will be delivered

The student will undertake a project in a research laboratory under the supervision of a member of academic staff.  The results will be presented in a written report.

Skills that will be practised and developed

Intellectual skills

The student will be able to show a detailed and advanced mastery of a specific topic at the research frontier level.

Chemistry –specific skills

The student will be able to:

a) plan and carry out an original investigation in a topic from any part of practical or theoretical chemistry;

b) select source literature and place it within the context of the project, with critical assessment of preceding work;

c) record all working notes in an appropriate manner, with reference to risk and hazard where applicable;

d) plan and compose a detailed report in standard format on all aspects of the project.

Transferable skills

The student will be able to present and defend a case following detailed study.

How the module will be assessed

Assessment will be based both on performance in the laboratory and the quality of the written report.

Assessment Breakdown

Type % Title Duration(hrs)
Dissertation 100 SHORT PROJECT FOR EXCHANGE STUDENTS N/A

Syllabus content

This module consists of one supervised research project spread over a single semester, in any suitable area of chemistry. The work will include new studies, a literature survey, and preparation of a project report. Topics will normally involve practical laboratory work, but projects with a large theoretical component are also possible, in appropriate areas.


CHT008: Research Project

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT008
External Subject Code 100417
Number of Credits 60
Level L7
Language of Delivery English
Module Leader Dr David Miller
Semester Dissertation Semester
Academic Year 2025/6

Outline Description of Module

This module consists of a supervised research project taking place during the summer semester or in the autumn semester for you taking a delayed project due to summer resits.  

 

The topic is selected from a portfolio prepared by members of staff from their own research interests. 

 

The work will require new studies in which a problem at the leading edge of a current area of chemistry will be tackled using original research. For assessment the module will require you to carry out a detailed literature survey, and preparation of a project report and a research presentation, both of which will be examined orally.  

On completion of the module a student should be able to

Module Learning outcomes: 

  1. Develop independent skills in designing and executing experimental procedures and techniques, to solve novel chemistry problems, within a team, as supported by an academic supervisor and their senior research team members.  

  1. Comprehensively explain and critique the chemistry underlying the chosen project to a specialist or lay audience.  

  1. Critically and independently evaluate hazardous chemicals and procedure for handling them so that laboratory work can be performed safely and efficiently in research level tasks.  

  1. Critically evaluate current and recent literature/advanced scholarship in the area and employ this to innovate and devise new experiments and/or simulations as the project evolves.  

  1. Disseminate results in both report and oral format and defend their work and decision making to peers who have critically evaluated the work. 

How the module will be delivered

 

Independent investigation, in research laboratories, in silico and in university library resources, supervised by a member of academic staff or their nominee from the relevant research team.  

 

Cohort level support will be provided in the form of seminars and workshops in essential skills, including Health and Safety (including COSHH), widely used spectroscopic techniques (e.g. NMR spectroscopy), academic writing and presentation.  

 

You will be invited to and expected to attend the School’s weekly research seminars. 

 

Skills that will be practised and developed

 

Chemistry-Specific Skills: 

 

On completion of the module the student will be able to: 

 

  • Plan and carry out an original investigation in a topic from any part of practical or theoretical chemistry; 

  • Select source literature and place it within the context of the project, with critical assessment of preceding work; 

  • Record working notes in an appropriate manner, with reference to risk and hazard where applicable; 

  • Plan and compose a detailed report in standard format on all aspects of the project; 

  • Present a lecture about the work and answer questions in oral examination. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

  

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 4. Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all 

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, and decent work for all 

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

Goal 12. Ensure sustainable consumption and production patterns  

Goal 13. Take urgent action to combat climate change and its impacts  

Goal 14. Conserve and sustainably use the oceans, seas, and marine resources for sustainable development 

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development 

How the module will be assessed

The module will be assessed on the basis of: 

Intellectual and Practical contribution – this is scored by the project supervisor and is 20% of the total module mark.  (Module Learning Outcomes 1,3 and 4) 

Assessed Dissertation (report).  Examiners will read the report and mark according to the assessment criteria. 40% of the module mark.  (Module Learning Outcomes, 2,4 and 5) 

Oral Presentation (20%) and viva voce examination (20%).  The final examination will be a 20 minute oral presentation delivered by the student which will be followed by a 30-40 minute oral examination. (All module learning outcomes will be assessed here). 

 

Formative assessment will be delivered on an ongoing basis by supervisors and their senior research team.  Oral presentation practice sessions will be organised within the groups and 

  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.  

 

Resit assessments will be held in the Resit Examination period, prior to the start of the following academic session or in the following academic session should further practical work be required.  

Reassessment will consist of a second attempt at report, oral presentation and/or oral examination, depending on which parameters were failed in the first attempt.  In extreme cases it may be necessary to repeat the laboratory work in the following academic year.  

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 40 Written Report N/A
Practical-Based Assessment 20 Intellectual and/or Practical Contribution N/A
Presentation 20 Oral Presentation N/A
Oral/Aural Assessment 20 Oral Examination N/A

Syllabus content

This module consists of one supervised research project spread over two semesters, in any suitable area of chemistry. 

The work will include new studies, a literature survey, and preparation of a project report which will be examined orally. 

Topics will normally involve practical laboratory work, but projects with a large theoretical component are also possible, in appropriate areas. 

 


CHT008: Research Project

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT008
External Subject Code 100417
Number of Credits 60
Level L7
Language of Delivery English
Module Leader Dr David Miller
Semester Dissertation Semester
Academic Year 2025/6

Outline Description of Module

This module consists of a supervised research project taking place during the summer semester or in the autumn semester for students taking a delayed project due to summer resits. 

The topic is selected from a portfolio prepared by members of staff from their own research interests.

The work will require new studies in which a problem at the leading edge of a current area of chemistry will be tackled using original research. For assessment the module will require all students to carry out a detailed literature survey, and preparation of a project report and a research presentation, both of which will be examined orally. 

On completion of the module a student should be able to

Module Learning outcomes: 

  1. Have developed independent skills in designing and executing experimental procedures and techniques, to solve novel chemistry problems, within a team, as supported by an academic supervisor and their senior research team members.  

  1. Comprehensively explain and critique the chemistry underlying the chosen project to a specialist or lay audience.  

  1. When appropriate, critically and independently evaluate hazardous chemicals and procedure for handling them so that laboratory work can be performed safely and efficiently in research level tasks.  

  1. Critically evaluate current and recent literature/advanced scholarship in the area and employ this to innovate and devise new experiments and/or simulations as the project evolves.  

  1. Disseminate results in both report and oral format and defend their work and decision making to peers who have critically evaluated the work. 

How the module will be delivered

Independent investigation, in research laboratories, in silico and in university library resources, supervised by a member of academic staff or their nominee from the relevant research team. 

Cohort level support will be provided in the form of seminars and workshops in essential skills, including Health and Safety (including COSHH), widely used spectroscopic techniques (e.g. NMR spectroscopy), academic writing and presentation. 

Students will be invited to and expected to attend the School’s weekly research seminars. 

Skills that will be practised and developed

 

Chemistry-Specific Skills: 

 

On completion of the module the student will be able to: 

 

  • Plan and carry out an original investigation in a topic from any part of practical or theoretical chemistry; 

  • Select source literature and place it within the context of the project, with critical assessment of preceding work; 

  • Record working notes in an appropriate manner, with reference to risk and hazard where applicable; 

  • Plan and compose a detailed report in standard format on all aspects of the project; 

  • Present a lecture about the work and answer questions in oral examination. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

  

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Graduate Attributes – Assessment:    

 

Presentation                                20% 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals   

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding.  

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Oral Assessment                         20%  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals   

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding.  

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Practical Assessment                  20% 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals   

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding.  

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Dissertation                                 40% 

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals   

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding.  

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 4. Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all 

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, and decent work for all 

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

Goal 12. Ensure sustainable consumption and production patterns  

Goal 13. Take urgent action to combat climate change and its impacts  

Goal 14. Conserve and sustainably use the oceans, seas, and marine resources for sustainable development 

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development 

How the module will be assessed

The module will be assessed on the basis of: 

Intellectual and Practical contribution – this is scored by the project supervisor and is 20% of the total module mark.  (Module Learning Outcomes 1,3 and 4) 

Assessed Dissertation (report).  Examiners will read the report and mark according to the assessment criteria. 40% of the module mark.  (Module Learning Outcomes, 2,4 and 5) 

Oral Presentation (20%) and viva voce examination (20%).  The final examination will be a 20 minute oral presentation delivered by the student which will be followed by a 30-40 minute oral examination. (All module learning outcomes will be assessed here).

Formative assessment will be delivered on an ongoing basis by supervisors and their senior research team.  Oral presentation practice sessions will be organised within the groups.

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

Resit assessments will be held in the Resit Examination period, prior to the start of the following academic session or in the following academic session should further practical work be required.  

Reassessment will consist of a second attempt at report, oral presentation and/or oral examination, depending on which parameters were failed in the first attempt.  In extreme cases it may be necessary to repeat the laboratory work in the following academic year. 

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 40 Written Report N/A
Practical-Based Assessment 20 Intellectual and/or Practical Contribution N/A
Presentation 20 Oral Presentation N/A
Oral/Aural Assessment 20 Oral Examination N/A

Syllabus content

This module consists of one supervised research project spread over two semesters, in any suitable area of chemistry. 

The work will include new studies, a literature survey, and preparation of a project report which will be examined orally. 

Topics will normally involve practical laboratory work, but projects with a large theoretical component are also possible, in appropriate areas. 

 


CHT203: Heterogeneous Catalysis

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT203
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Professor Stuart Taylor
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module will provide insight into the importance of heterogeneous catalysis in the modern world, and it will allow you to learn how it is applied for societal benefit. It will demonstrate the diverse applications of heterogeneous catalysis and its importance to both the modern chemical industry and protecting the environment. 

It will outline the essential fundamental concepts and methodologies available for studying these processes, as well as showing you molecular level mechanisms and principals involved in catalysis.  

Processes covered include oxidation reactions, car exhaust treatment, reducing NOx emissions from stationary sources, and acid-catalysed reactions. The importance of heterogeneous catalysts and their applications in environmental applications and sustainability will be outlined and addressed. For particular applications, examples of several types of catalysts, including supported metals, metal oxides, and zeolites, will all be presented and discussed.  

We will cover key details and catalyst characteristics, as well as the typical attributes and preparation of a heterogeneous catalyst. We will assess a catalyst's performance, provide quantitative descriptors, and discuss catalyst deactivation processes.  

We will examine heterogeneous catalyst mechanisms and contrast the various models. The Langmuir-Hinshelwood, Eley-Rideal, and Mars van Krevelen mechanisms will be addressed, and experimental methods used to identify mechanism will be covered.  

We will approach the specifics of how heterogeneous catalysts are utilised in various reactor types, covering both laboratory and industrial scales. The various physical forms of the catalysts will also be taken into account in the context of various reactors and performance optimization.  

On completion of the module a student should be able to

On successful completion of the module, you should be able to: 

  • Describe the fundamental principles and mechanisms of heterogeneous catalysts and outline how they are applied to a range of reactions used in modern industrial processes, new sustainable processes, and environmental protection.   

  • Evaluate experimental data from performance of heterogeneous catalysts and relate this to key catalyst characteristics to establish an understanding between structure, composition, and chemistry.   

  • Propose mechanisms for heterogeneously catalysed transformations covering a wide range of chemistry and recommend appropriate experimental methodology to establish the mechanism.   

  • Apply concepts of heterogeneous catalysis to propose catalysts and key functionality that are required to catalyse a specific reaction, which may be related to presented examples or an unseen transformation.   

  • Examine critically a catalytic process that is currently operated at scale, based on analysis of information from the literature prioritise the key findings to summarise factors that make the process successful.  

How the module will be delivered

You will receive course content delivered primarily using face to face lectures. 

The course consists of 22 lectures across the Spring semester, with approximately 2 lectures each week.  

Lectures may include some worked problems and informal formative questions to support principles introduced. 

These will help you to address the learning outcomes and provide opportunities to apply knowledge and develop understanding.   

The lecture schedule will follow the module map published prior to the start of the module. 

Lectures will be recorded and will be available following the live sessions. A combination of lecture slides and additional supporting notes will be available for you prior to the face-to-face lectures. 

Lecture material will be supported by three workshops. 

Two workshops will be formative and will take the form of face-to-face sessions, and these will focus on supporting problem solving based on material from lectures. 

A single summative workshop will focus on research into a self-selected industrial catalytic process, and you will attempt this over a timescale of several weeks using independent study. 

You will be required to submit a one-page critical narrative summary for assessment.  

Skills that will be practised and developed

Skills developed through formal module learning outcomes and summative assessment are:  

 

Academic Skills: 

 

  • The module develops a number of your transferable skills, such as problem solving, numeracy, information searching and critical analysis of information, all of which are important for enhancing employability.   

 

  • Through the summative assessment exercise, you will be able to demonstrate ability to research a new area of catalysis to you, and critically assess and prioritise information so it can be communicated precisely and effectively.  

 

  • The formative assessments will allow for collaborative working when discussing concepts and their application to problem solving.  

 

 

Chemistry-Specific Skills: 

 

  • You will develop chemistry specific skills, some aspects will focus on applying ideas introduced in earlier modules, these will include kinetics, thermodynamics, solid state chemistry and surface chemistry, along with some new ones.  

 

  • You will apply these fundamental concepts to understand heterogeneous catalysts and how they operate. Application of these fundamental principles will reinforce your skills in application to critical problem solving and understanding. 

 

  • Developing these skills in the principles of heterogeneous catalysis will allow you to start to select appropriate catalysts for specific target reactions and appreciate how catalysts could be applied to solve pressing issues around sustainability, reaching net zero carbon targets and tackling environmental challenges.   

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

Written Report            30% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Exam                          70% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Sustainable Development Goals:   

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:  

  

  • Goal 6. Ensure availability and sustainable management of water and sanitation for all 

  • Goal 7. Ensure access to affordable, reliable, sustainable and modern energy for all 

  • Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

  • Goal 12. Ensure sustainable consumption and production patterns 

  • Goal 13. Take urgent action to combat climate change and its impacts 

  • Goal 14. Conserve and sustainably use the oceans, seas and marine resources for sustainable development 

How the module will be assessed

Summative assessment will take the form of a written examination and a workshop piece of coursework.  

A two-hour closed book written exam will test your ability to demonstrate knowledge and understanding of the syllabus content, and your ability to apply the techniques and concepts covered to problems solving that are related to familiar and unseen examples.   

The summative workshop coursework will consist of 1 workshop. This will allow you to demonstrate your ability to use widely available scientific resources to locate relevant information and to critically review literature knowledge through the preparation of a short-written report. Marks will reflect the extent to which you have met the module learning outcomes, and you will be provided with detailed marking criteria. You will receive feedback on your work well before the written exam.  

Your learning will also be supported by two formative workshops, and feedback provided either orally or in written form after the face-to-face session. There will be a focus on supporting problem solving based on applying knowledge and understanding of heterogeneous catalysis.   

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:   

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.  

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session.   

 

Assessment Breakdown

Type % Title Duration(hrs)
Report 30 Written Report N/A
Exam - Spring Semester 70 Heterogeneous Catalysis 2

Syllabus content

The module will begin by covering the basic fundamental aspects and applications of heterogeneous catalysis, including the effects of catalysts on reaction rates and product distribution, requirements for practical catalysts, and the design of catalysts with attention to active phases, supports and promoters. 

   

Approaches to catalyst preparation will be covered, and several techniques used to characterise heterogeneous catalysts will be introduced.  

 

These will include temperature-programmed methods to monitor adsorption, oxidation, reduction, and desorption processes.  

 

Surface area and porosimetry by nitrogen physisorption and active metal surface area determination by chemisorption. The application of transmission and scanning electron microscopy to understand the structure of catalysts at the microscopic scale will be included.   

 

Principles and application of heterogeneous catalysts will be augmented by many examples. These will include catalysts for: 

 

(a) water gas shift;  

(b) refining processes;  

(c) production and use of syngas, and catalytic routes to ammonia and methanol;  

(d) atmospheric pollution control, with particular reference to the 3-way vehicle exhaust catalyst and selective catalytic reduction for stationary NOx emission control.   

 

The types of reactors used to apply heterogeneous catalysts will be introduced and the important features will be discussed.  

 

Two classes will be covered: 

 

(a) gas/solid reactors 

(b) gas/liquid/solid reactors, the physical forms of the catalysts employed in the different reactors will be explained.  

 

The role of the catalytic reactor in an overall chemical process will be presented.   

 

Quantitative aspects of catalyst performance will be explained, covering gas hourly space velocity, conversion, product selectivity, rates of reaction and some kinetic parameters.   

 

Some examples of different catalysts will be covered by in-depth case studies for environmental protection applications. These will be the three-way catalytic converter for control of petrol vehicle emissions and controlling NOX emissions from stationary sources.  

 

Other different types of heterogeneous catalysts, like those that are applied to bio renewable and sustainable processes, will also be presented.  

 

Examples are zeolites, supported metals and metal oxides, these examples will present a number of different catalytic mechanisms, and will include Langmuir-Hinshelwood, Eley-Rideal and Mars-van Krevelen types, experimental methodologies to distinguish between these mechanisms will be investigated.  

 

The relationships between experimental catalyst activity data and catalyst structure will be discussed in the context of catalyst mechanism.   

 

Mechanisms of catalyst deactivation will be explored and illustrated with various examples.   

Essential Reading and Resource List: 

 

  • M. Bowker, The Basis and Applications of Heterogeneous Catalysis, Oxford Chemistry Primers, 1998, ISBN 0198559585   

  • Background Reading and Resource List    

  • J. M. Thomas, W. J. Thomas, Principles and Practice of Heterogeneous Catalysis, ISBN: 978-3-527-29239-4  


CHT206: Structure and Mechanism in Organic Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT206
External Subject Code 100422
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Niklaas Buurma
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

 

This module outlines, the techniques and approaches of physical organic chemistry that are be used to study mechanisms of organic, bioorganic, and catalytic reactions and MO theory as applied to the analysis of organic reactions, including in pericyclic reactions. 

On completion of the module a student should be able to

 

  • Propose a reasonable and falsifiable reaction mechanism for a reaction based on interpretation of physical and/or structural data. 

  • Propose experiments and predict outcomes of experiments designed to falsify proposed reaction mechanisms. 

  • Critically evaluate publications reporting studies of reaction mechanisms and orally report on the findings. 

  • Predict or rationalise the outcome of pericyclic processes, including periselectivity, regioselectivity and stereoselectivity based on analysis of molecular orbital interactions. 

How the module will be delivered

 

The module is taught using a combination of online recordings, interactive workshop-style lectures, a workshop, and a presentation session as detailed in the weekly module map.  

 

The online recordings present the required theory and you are required to watch the recordings before the corresponding interactive workshop-style lectures.  

 

The interactive lectures then apply the theory as presented in the recordings to exam-style problem-solving exercises.  

 

The workshop is used to explain what is required from the coursework and to allow you to form groups for their presentations.  

 

During the presentation session, you will deliver their summatively assessed group presentation. 

     

Skills that will be practised and developed

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 

Graduate Attributes – Assessment:    

 

Group Presentation              30%  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Exam                                   70% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

  

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture 

Goal 12. Ensure sustainable consumption and production patterns  

 

How the module will be assessed

 

The module will be assessed through a group presentation and an exam. 

 

The summatively assessed group presentation assesses the student’s ability to critically evaluate publications reporting studies of reaction mechanisms and orally report on the findings, to work as a group to develop a presentation and to deliver an oral presentation on a mechanistic study.  

 

The marking criteria are the group’s ability in linking data to mechanism a clear demonstration of how mechanism is supported by results from experiments is expected), in critical analysis (comments on quality of data and suggestions for future work are expected) and in quality of presentation (quality of slides, sequence of material & structure of presentation, coherence of presentation are assessed).  

 

The group is awarded a group mark from which individual marks are decided through peer marking, so that the average of the individual marks corresponds to the group mark.  

 

The exam assesses the student’s ability to propose a reasonable and falsifiable reaction mechanism for a reaction based on interpretation of physical and/or structural data; propose experiments and predict outcomes of experiments designed to falsify proposed reaction mechanisms; predict or rationalise the outcome of pericyclic processes, including periselectivity, regioselectivity and stereoselectivity based on analysis of molecular orbital interactions. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

A resit exam and a resit presentation will be offered if required. The resit presentation is an individual presentation instead of a group presentation.  

 

Assessment Breakdown

Type % Title Duration(hrs)
Presentation 30 Group Presentation N/A
Exam - Spring Semester 70 Structure and Mechanism in Organic Chemistry 2

Syllabus content

 

Kinetics techniques in mechanistic studies: experimental methods for the acquisition of kinetic data; data analysis, curve fitting, statistics, and error analysis; simple rate laws; analysis of kinetic data in terms of reaction mechanisms; complex rate laws; numerical integration techniques 

            

Determination and interpretation of activation parameters in mechanistic studies: Gibbs energies and standard states; Δ‡Hø, Δ‡Sø and Δ‡V and their interpretation 

  

General & specific acid and base catalysis in mechanistic studies: pH rate profiles; equations and data analysis; mechanisms leading to general/specific acid/base catalysis 

  

Linear free energy relationships in mechanistic studies: Brønsted plots; Hammett plots 

 

Use of isotopes in mechanistic studies: isotopic labelling; cross-over experiments; primary kinetic isotope effects; solvent isotope effects 

 

Proposing reasonable reaction mechanisms: application of the techniques above to proposing reasonable reaction mechanisms 

 

MO theory as applied to non-pericyclic organic reactions: The application of MO theory to various organic reactions; stereoelectronic effects. 

  

MO theory as applied to pericyclic reactions: cycloadditions (including Diels-Alder and dipolar cycloadditions); symmetry-allowed and symmetry-forbidden reactions, regioselectivity, stereoselectivity; sigmatropic rearrangements; 1, n hydride shifts, Cope and Claisen rearrangements; electrocyclic reactions; photochemical processes; synthetic strategies involving pericyclic processes 


CHT214: Biocatalysis I: Modern Approaches to Biocatalysts

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT214
External Subject Code 100948
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr David Miller
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

Biocatalysis is an interdisciplinary subject that sits at the cutting edges of chemistry, biology, and the sustainable production of industrially important chemicals. There will be a focus in this module on biocatalysts that are naturally occurring or engineered enzymes, which can catalyse transformations with high levels of regioselectivity and stereoselectivity. 

This module will first remind students of the structure of fundamental building blocks of life (primarily proteins and nucleic acids), as a prelude to understanding how the enzymes needed for biocatalysis are produced in large amounts. In addition, some basic principles of enzyme kinetics and catalytic mechanism will be revised. We will then bring the students up to speed on the state-of-the-art in nucleic acid synthesis, amplification, and sequencing. 

Students will be introduced to current methods of biotechnology for the production and manipulation of proteins that have applications spanning research, green manufacturing, and biopharmaceuticals. Problems with existing methods will be discussed and strategies for their solution will be presented. 

Finally, students will be shown the molecular basis for biocatalytic applications of a series of enzymes, such as proteinases, with an emphasis on methods for evaluating and controlling the stereochemical outcome of these transformations.  

On completion of the module a student should be able to

  • Have a critical awareness of the place biocatalysis has within the biotechnology and chemistry toolkit; having a comprehensive understanding of its advantages and disadvantages relative to other catalytic techniques.  

  • Have a systematic knowledge of methods for preparation of enzymes for biocatalysis and hence have the critical awareness necessary to propose appropriate production strategies for wild type and engineered biocatalysts.  

  • Have a comprehensive and systematic understanding of biocatalytic process including catalytic enzyme mechanism and cofactor regeneration associated with using enzymes outside of cells.  

  • Evaluate and propose novel methods for the asymmetric generation of organic molecules using the toolkit of biocatalysis presented herein, when challenged with unseen problems.  

How the module will be delivered

A blend of online learning activities with face-to-face learning support and feedback. 

The module will be delivered by 12 x 1-hour lectures and 2 x 1-hour tutorials supported by 2 x formative workshops. Some aspects may be delivered by pre-prepared video for supplementary support. 

The two module tutors will deliver half the material each with the final exam featuring two questions from each tutor. Hence the formative workshop from each tutor will be aimed at supporting learning for their examination questions. 

Skills that will be practised and developed

Academic Skills: 

 

  • Students will gain experience in project planning and problem-solving in the field of biocatalysis using both whole cells and isolated and purified enzymes. 

 

Chemistry-Specific Skills: 

 

  • You will gain experience in the evaluation of biocatalysis performance and limitations with regard to a range of asymmetric synthetic transformations and kinetic resolutions. 

  • You will develop the skills required to create solutions to unseen problems in biocatalysis for the synthesis of organic chemicals and propose strategies of the preparation and purification of biocatalysts. 

  • You will develop the knowledge and understanding necessary to explain the catalytic mechanism of a variety of biocatalysts and how their structures form and contribute to their activity. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

Coursework                  30% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Exam                            70% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Resit Exam                   100% 

  •   

  • Consider own personal and professional ethical, social, and environmental responsibilities. 

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 3. Ensure healthy lives and promote well-being for all at all ages

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation

Goal 12. Ensure sustainable consumption and production patterns

Goal 14. Conserve and sustainably use the oceans, seas, and marine resources for sustainable development  

How the module will be assessed

A written exam (70%) will test the student’s knowledge and understanding as elaborated under the learning outcomes. An assessed workshop (30%) through a submitted coursework assignment will allow the student to demonstrate their ability to solve problems, and to judge and critically review relevant information from the primary scientific literature and provide practice for the examination.  

A prior formative coursework problem sheet will give students practice in this assessment after each half of the delivered lecture material.  

Any academic or competence standards which may limit the availability of adjustments or alternative assessments for disabled students should be clearly stated in line with guidance provided in the Reasonable Adjustment Policy and Procedure  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 30 Workshop problem sheet N/A
Exam - Autumn Semester 70 Biocatalysis 1: Modern approaches to biocatalysts. 2

Syllabus content

All content is mandatory. 

 

Protein and RNA chemistry  

Protein and nucleic acid structure and function. 

Enzyme catalysis  

Thermodynamics of protein folding and substrate binding. Active site structure and the molecular basis of catalysis, including the use of co-factors. The Michaelis-Menten model of enzyme kinetics  

Recombinant DNA technology  

Tools for the manipulation of DNA (endonucleases, ligases, DNA polymerases). Methods of DNA synthesis, amplification, and sequencing  

Obtaining enzymes in bacterial expression systems  

Isolation and purification of recombinant proteins. Modification of proteins by site-directed mutagenesis.  

Advanced topics in biocatalysis, use of enzymes to catalysis asymmetric organic transformations:  

Lipases, esterases and proteinases. Epoxide hydrolases. Dehydrogenases. Use of enzymes in organic solvents. Cofactor chemistry and recycling strategies. Kinetic resolution and dynamic kinetic resolution.  


CHT216: Colloquium

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT216
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Niklaas Buurma
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module trains students in searching, retrieving, managing and subsequent analysis and critical discussion of current scientific literature in a specialised area of research.  

The module will develop written communication skills through the preparation of a written literature review report in one of the standard formats (e.g. RSC and ACS). The module will also develop oral communication skills.  

Each student works on their own specialised chemical topics and these topics are typically aligned with the topic of the student’s Part II project. 

On completion of the module a student should be able to

  • Collect, manage, and critically review a body of scientific literature in a specialised area of knowledge. 

  • Critically evaluate the published interpretations of data and generate alternative interpretations where appropriate. 

  • Develop and support a professional opinion in a specialised area of knowledge using scientific literature. 

  • Report (in writing and orally) chemical information at a professional standard. 

How the module will be delivered

The module is delivered through two 2-hour workshops on handling scientific literature. Further support on reviewing scientific literature and delivering presentations is provided through a wide range of material for self-study as required in learning modules on Learning Central. 

Supervision during the preparation of a written report and a presentation will be provided by the member of staff proposing the topic of the literature study. A minimum of three meetings between the student and the project supervisor is anticipated (one to discuss the topic of the review, one to discuss an early draft of the literature review and one to discuss a late draft of the literature review). 

These meetings will enable and support student learning of complex and specialised knowledge and skills, but the student is expected to develop the autonomous learning processes associated with the preparation of critical literature reviews. 

Skills that will be practised and developed

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

  

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Understand organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Graduate Attributes – Assessment:    

  

 Presentation                   50% 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Understand organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

 

 Dissertation                     50% 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Understand organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development 

How the module will be assessed

The presentation and the report will allow the student to:  

 

(a) demonstrate his/her ability to judge and critically review a significant body of existing literature in a specialised area of research; 

(b) present results from a study of the scientific literature in both written and oral form. The assessment criteria are provided to students on Learning Central in the form of the marking forms used by the markers. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

The format of the reassessment is the same as the format of the original assessments. 

Assessment Breakdown

Type % Title Duration(hrs)
Dissertation 50 Written report N/A
Presentation 50 Oral Presentation N/A

Syllabus content

  • Application of information technology in chemistry 

  • Writing of reports in one of the standard formats in chemistry 

  • Plagiarism and its potential consequences 

  • Oral presentation and scientific discussion 

  • The module consists of a literature review of a specialised area of knowledge, resulting in a written report and an oral presentation. Students are allocated a supervisor and agree a topic which can be in any area of the student’s MSc programme but must be focussed on chemical aspects of the selected topic. 


CHT217: Catalyst Design Study

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT217
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Dr Jonathan Bartley
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module provides students with the opportunity to work in small teams to design a new catalyst system for a given problem. Students must use their knowledge and the literature to understand the current state of the art and why an alternative catalyst may be needed. The study will be assessed by the production of a detailed report and an oral/poster presentation.

On completion of the module a student should be able to

  • Identify catalysis concepts underpinning solutions to a complex open-ended problem.
  • Identify and critically evaluate information from multiple sources.
  • Make appropriate assumptions and estimate relevant quantities.
  • Propose a project solution that shows due consideration of the physical, social, political, economic, environmental, technological and regulatory contexts.
  • Demonstrate an ability to work in groups under time pressure.
  • Report orally and in writing to different stakeholders.

How the module will be delivered

This module provides students with the opportunity to work in small teams to design a new catalyst system for a given problem. Students must use their knowledge and the literature to understand the current state of the art and why an alternative catalyst may be needed. The study will be assessed by the production of a detailed report and an oral/poster presentation.

The module CHT216 (Colloquium) will provide essential background work on how to use the literature for the purposes of this study and so is an essential co-requisite module.

Skills that will be practised and developed

This is a research, design and problem-solving module in which students are expected to integrate initiative and creativity with a detailed subject knowledge of catalysis.

Specifically, students are expected to:

 

  • Identify existing knowledge and learning needs to address the challenge
  • Demonstrate independent learning ability
  • Plan and manage their time and a variety of tasks in order to meet deadlines
  • Communicate clearly through report writing and briefing documents
  • Work effectively as part of a group and in consultation with specialists
  • Clearly communicate intentions, processes and solutions the problem through visual, oral and written presentation to professional and academic audiences.

How the module will be assessed

The module will be assessed through an individual report taking the form of a written project proposal (around 15 typed A4 pages, including figures and references) and a group oral/poster presentation (45 minutes). Reports and presentations will be assessed by staff for originality of ideas, soundness of methods, feasibility of project plan, structure and clarity, quality of presentation. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:

 

The module will be reassessed through additional written coursework and/or presentations over the summer. Reassessment coursework will consist of resubmission of a project proposal. Resitting students will not normally be allocated a new problem, and other members of a student’s group would not be expected to contribute unless they were also being reassessed.

Assessment Breakdown

Type % Title Duration(hrs)

Syllabus content

The scientific and technical subject matter will be based on concepts developed during the MSc/MRes programme. Students will be expected to supplement this with their own independent literature research.

The content of the reports will be flexible depending on the problem and solution put forward. However, projects should involve consideration of several of the following:

 

  • Understanding existing literature related to the project
  • Selection or design of catalysts that exhibit desired properties
  • Developing synthetic routes to catalysts
  • Analytical and measurement techniques for identification and characterisation of materials
  • Sourcing and costs of raw materials, equipment, services and human resources
  • Health, safety and the environment
  • Intellectual property

CHT219: Preparation and Evaluation of Heterogeneous Catalysts

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT219
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Jonathan Bartley
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module describes the preparation, characterisation and testing of heterogeneous catalysts. The aim of the module is to give students a fundamental understanding of the different techniques and an appreciation of how the information obtained can be used to gain insight into structure activity relationships for different heterogeneous catalysts.

On completion of the module a student should be able to

Knowing (these are things that all students will need to be able to do to pass the module):

  • Students should demonstrate awareness of the different methods for synthesising heterogeneous catalysts and the impact these have on the properties.
  • Students should demonstrate a fundamental understanding of how different characterisation methods work and the information that can be obtained for heterogeneous catalysts from each.

Acting (Performance in this area will enable students to achieve more than a basic pass):

  • Evaluate experimental data from the testing of heterogeneous catalysts to critically assess their performance.
  • Understand and interpret characterisation data to extract chemically relevant properties.

Being (Performance in this area will enable students to achieve more than a basic pass):

  • Critically assess characterisation data to identify unknown materials.

How the module will be delivered

The module will consist of 11 × 2 hour lectures that will introduce the synthetic and characterization techniques that address the “Knowing” Learning Outcomes. The lectures will include problem solving examples as to how the data generated by the different techniques can be used to provide information about heterogeneous catalysts to develop the skills necessary to achieve the “Acting” and “Being” Learning Outcomes.

Skills that will be practised and developed

Students will develop a detailed understanding of how properties of heterogeneous catalysts can be elucidated using different characterisation techniques and testing procedures and how these are related to their structure and performance.

 

The module will involve a large element of problem solving across a range of spectroscopic and characterisation techniques to gain fundamental information about catalysts. Students will be able to apply this new understanding to solve previously unseen problems and to identify unknown materials from characterisation data.

How the module will be assessed

Summative assessment: The module will be assessed by a 2h written examination that will test the student’s knowledge gained from the lecture course (“Knowing” Learning Outcomes) and the ability to solve problems by integrating this knowledge with previously unseen information (“Acting” and “Being” Learning Outcomes).

The coursework will be a problem solving-based exercise. Marks will reflect the extent to which students have met the module learning outcomes shown above.

Formative assessment: The lectures will include problem solving examples as to how the data generated by the different techniques can be used to provide information about heterogeneous catalysts to develop the skills necessary to achieve the “Acting” and “Being” Learning Outcomes.

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:

Students who are permitted by the Examining Board to be reassessed in this module during the same academic session will sit an examination (2 h) during the Resit Examination Period.

Assessment Breakdown

Type % Title Duration(hrs)

Syllabus content

Different methods of catalyst preparation will be introduced and their influence on the properties of the resultant materials will be explained. For supported catalysts, calculations of important concepts such as dispersion will be demonstrated as well as calculating the quantities of precursors and supports required for a particular catalyst formulation.

A number of characterisation techniques/research methods will be described, with a brief introduction to the technique, the fundamentals of how the technique works and the information that can be gained, a general discussion of their scope and limitations, applicability and relevance to catalysis research.

Data interpretation and the application of it to the understanding of catalyst properties and structure-activity relationships will be introduced for the different techniques.

Examples of techniques included in the course are:

Impregnation, sol immobilisation, X-ray diffraction, Raman spectroscopy, thermogravimetric analysis, X-ray photoelectron spectroscopy, EPR/ENDOR spectroscopy, surface area measurement, electron microscopy, temperature programmed reduction/oxidation/desorption and catalyst testing.


CHT221: Mechanism and Ligand Design in Homogeneous Catalysis

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT221
External Subject Code 101389
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Benjamin Ward
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module will focus on the structure, influence, and design of ligands in the development of functional metal complexes and main-group compounds. 

Three areas will be covered, representing a cross section of pertinent problems in this area, these will be: 

(a) the chemistry and catalytic applications of d0 metal complexes;  

(b) the study of N-heterocyclic carbene complexes and their catalytic chemistry; 

(c) the stoichiometric and catalytic reactions of frustrated Lewis pairs.   

The module will cover the synthesis of ligand precursors, coordination chemistry, including in cases where there is no electronic preference to coordination geometry, and homogeneous catalysis.   

Attention will be given to the analysis of structure-activity relationships and the interpretation of catalytic data in terms of reaction mechanisms. 

On completion of the module a student should be able to

  • Formulate a catalytic reaction mechanism within unfamiliar operating parameters (e.g. catalyst and/or substrate structure). 

  • Critically evaluate catalytic reaction data in terms of the likely reaction mechanism, substrate structure, and catalyst design; assess structure-reactivity effects of ligands and formulate reactivity patterns. 

  • Design an appropriate synthetic strategy for ligands and complexes within provided constraints. 

  • Choose appropriate analytical techniques to characterise chemical species and assess analytical data in terms of chemical structure. 

 

How the module will be delivered

The module will be delivered in 10 2-hour lectures and three 1-hour tutorials. 

The module consists of three distinct blocks, each covering a different aspect of advanced ligand design and coordination chemistry.  

 

The three blocks will mirror the three sections described above:  

(a) catalysts based on d0 metal complexes;  

(b) N-heterocyclic carbene complexes in catalysis;  

(c) the catalytic chemistry of frustrated Lewis pairs.  

 

Each block will be followed by a tutorial in which problem-solving and analytical skills are practised. 

Skills that will be practised and developed

Chemistry-Specific Skills: 

 

  • Students will already know how to construct a catalytic mechanism for simple catalysts and substrates (level 6); in this module students will learn how to analyse complex datasets and to formulate an explanation for trends and observations of chemical reactivity patterns 

  • Develop a level of understanding closer to situations expected in graduate-level employment.  

  • Students will refine their problem-solving skills in situations that require them to synthesise a coherent argument or explanation using knowledge/data from a number of different sources. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:  

   

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

 Coursework                      30% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 Exam                                70%  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

  •  

 

 Resit Exam                      100%  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:  

 

Goal 6. Ensure availability and sustainable management of water and sanitation for all. 

Goal 12. Ensure sustainable consumption and production patterns. 

Goal 13. Take urgent action to combat climate change and its impacts.  

How the module will be assessed

Formative assessment will be provided in the three tutorial sessions following each of the three theory blocks. These tutorials will be interactive and will develop the problem-solving skills required to apply the core lecture material to unfamiliar situations.

Summative assessment will take the form of coursework (20%) and written examination (80%). Coursework will consist of a single piece of work of three 10-mark questions; each question will be problem-based and will require students to apply concepts of ligand design to synthesise catalytic mechanisms within unfamiliar operating parameters. This will allow students to meet learning objectives 1 and 2.

The examination will consist of four 20-mark questions; students must answer any three. Questions will probe students’ ability to interpret data and to construct mechanistic arguments based on provided data, thus allowing students to meet learning objectives 3-4. 

 

Marking criteria 

50-60 Satisfactory appreciation of the key concepts of catalyst design and their structural influence on catalytic reactions. Work in this category will demonstrate the ability to design catalytic cycles to an unfamiliar substrate and/or catalyst that are similar (but not identical) to those given in lecture material. There will also be a demonstrable ability to construct a ligand and/or catalyst synthesis from the molecular types illustrated in the lecture material.

60-70 Good grasp of most concepts relating to catalyst performance in relation to catalyst and substrate structure. Will demonstrate the ability to relate material from across all areas of the course to synthesise a rational explanation for catalyst performance and chemical reactivity. Will be able to propose a more advanced chemical synthesis pathway and an appreciation for how analytical techniques can aid the understanding of catalyst performance.

70-100 Excellent demonstration of catalyst design and structural influence on catalytic reactions. An outstanding ability to make connections between different areas of knowledge to aid a thorough interpretation of unfamiliar data, providing a rigorous spectroscopic/mechanistic/structural analysis. The ability to demonstrate appropriate weighting in different parameters that can affect chemical reactivity as applied to an unfamiliar situation. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

The resit examination will adopt the same format as the main examination but will contain questions that allow students to demonstrate learning objectives 1-4. 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 30 Coursework N/A
Exam - Autumn Semester 70 Mechanism and Ligand Design in Homogeneous Catalysis 2

Syllabus content

The applications of ligand design and coordination chemistry to a range of areas, including catalysis and p-block chemistry, with an emphasis on the ability of controlling the properties and reactivity of metal complexes by ligand design. 

 

The properties of d0metals in polymerisation catalysis 

A detailed mechanistic understanding of the properties and reactivity of d0 metal alkyl and alkyl cations will be discussed.  These complexes have most widely studied in the context of alkene polymerisation, and this type of reactivity will be used to exemplify the reactivity of d0 complexes.  The level of detail moves on from that covered in level 6, encompassing the catalyst structures required for the production of stereospecific polymers and the influence of agostic interactions to facilitate migratory insertion reactions.  This theme will be expanded to introduce the polymerisation of cyclic esters, commonly used as biodegradable polymers. 

 

Heterofunctionalisation catalysis 

The role of d0metal complexes as catalysts for a range of organic transformations will be discussed, with particular focus on hydroamination, hydrogenation, hydrosilylation, and hydrophosphination.  A particular focus will be given to looking at the mechanisms of these reactions, for which there are less reaction steps possible (e.g. oxidative addition is precluded). This theme will be expanded to cover alkaline earth metals in catalysis, including their environmental benefits, their scope, and their limitations. 

 

N-heterocyclic carbenes 

- Introduction to N-Heterocyclic Carbenes (NHC) as ligands and their complexes with transition metals, providing knowledge of the routes to their synthesis as well as on their structure, reactivity, and electronic/steric properties. The scope and advantages of metal NHC compounds and their application in catalysis. 

 

p-Block organometallics 

Introduction to p-block organometallics, including structure and reactivity trends will be provided. This will lead to a detailed discussion of frustrated Lewis pairs (FLPs), and their role in catalysis. 


CHT223: Biocatalysis II: Industrial Applications of Biocatalysis

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT223
External Subject Code 100948
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr David Miller
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

Biocatalysis is an interdisciplinary subject that sits at the cutting edges of chemistry, biology, and the sustainable production of industrially important chemicals. Further applications of isolated enzymes in biocatalysis will be discussed and build on examples presented in CHT214. 

In addition, the use of naturally occurring or engineered microorganisms (whole cell biocatalysts) to obtain a variety of useful compounds will be outlined. 

The first part of the course will then discuss the use of metabolically transformed microorganisms for the production of small molecules (e.g. citric acid and other amino acids) and antibiotics (e.g. penicillin and erythromycin). 

The principles of re-engineering the metabolic pathways present in microorganisms will be presented together with their use in optimizing the yields of target compounds. 

Students will be shown how microorganisms can be used in environmental bioremediation and the conversion of biomass into high fructose corn syrup and biofuels. Problems with existing methods will be discussed and strategies for their solution will be presented.

Finally, this module will advance on the material taught in CHT214 (Biocatalysis I), providing students with more examples of the molecular basis for biocatalytic applications of enzymes, with an emphasis on methods for evaluating and controlling the stereochemical outcome of these transformations.

There will also be a limited discussion of how product inhibition, co-factor chemistries and the biophysical properties of enzymes influence reactor design and the feasibility of a reaction on an industrial scale. 

On completion of the module a student should be able to

  • Have a comprehensive knowledge of the principal types of organic transformations that can be catalysed by enzymes and/or whole-cell systems on the industrial scale.  

  • Propose appropriate asymmetric routes to novel/unseen small molecule targets employing biocatalysis and critique and propose alternatives to existing routes.  

  • Employ a comprehensive understanding of basic enzyme kinetics to the design of industrial processes faced with problems such as product inhibition.  

  • Evaluate methodologies and provide solutions for unseen problems in biocatalysis where novel, modern engineering of enzymes may be required.  

How the module will be delivered

A blend of online learning activities with face-to-face learning support and feedback.

The module will be delivered by 12 x 1-hour lectures and 2 x 1-hour tutorials supported by 2 x formative workshops. Some aspects may be delivered by pre-prepared video for supplementary support.

The two module tutors will deliver half the material each with the final exam featuring two questions from each tutor. Hence the formative workshop from each tutor will be aimed at supporting learning for their examination questions. 

Skills that will be practised and developed

Academic Skills: 

 

  • Students will gain experience in project planning and problem-solving in the field of biocatalysis using both whole cells and isolated and purified enzymes. 

 

Chemistry-Specific Skills: 

 

  • You will gain experience in the evaluation of biocatalysis performance and limitations with regard to a range of asymmetric synthetic transformations and kinetic resolutions, introducing further biocatalytic methodologies, building on the material delivered in CHT214. 

  • You will develop the skills required to create solutions to unseen problems in biocatalysis for the synthesis of organic chemicals and propose strategies of the preparation and purification of biocatalysts. 

  • You will develop the knowledge and understanding necessary to explain the catalytic mechanism of a variety of biocatalysts and how their structures form and contribute to their activity. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

 Coursework                     30% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 Exam                               70% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 Resit Exam                      100% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture

Goal 3. Ensure healthy lives and promote well-being for all at all ages

Goal 7. Ensure access to affordable, reliable, sustainable, and modern energy for all

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation

Goal 12. Ensure sustainable consumption and production patterns

Goal 14. Conserve and sustainably use the oceans, seas, and marine resources for sustainable development 

How the module will be assessed

A written exam (70%) will test the student’s knowledge and understanding as elaborated under the learning outcomes. An assessed workshop (30%) through a submitted coursework assignment will allow the student to demonstrate their ability to solve problems, and to judge and critically review relevant information from the primary scientific literature and provide practice for the examination. A prior formative coursework problem sheet will give students practice in this assessment after each half of the delivered lecture material. 

Any academic or competence standards which may limit the availability of adjustments or alternative assessments for disabled students should be clearly stated in line with guidance provided in the Reasonable Adjustment Policy and Procedure  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session. 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 30 Workshop problem sheet N/A
Exam - Spring Semester 70 Biocatalysis II: Industrial Applications of Biocatalysis. 2

Syllabus content

All content is mandatory: 

 

a) Biocatalysis versus chemical catalysis  

Understanding when to use a biocatalyst for a chemical problem.  Advantages/disadvantages of biocatalysts compared to traditional chemical reactions and heterogeneous/homogeneous catalysis.  Mild reaction conditions, excellent stereo-, chemo- and regio- selectivity versus substrate specificity, product inhibition, lack of catalyst robustness, cofactor recycling.  

 

(b) Isolated enzyme systems and whole cell systems.  Free and immobilized enzymes for biocatalysis.  Water versus organic solvent.  

 

(c) Enzyme structure – primary, secondary, tertiary, and quaternary structure. The amino acids, important side chains for reactivity.  Active site, lock and key and induced fit models. 

  

(d) Enzyme kinetics.  The Michaelis-Menten equation.  Product inhibition, cofactor requirements and how they relate to reactor design.  

 

(e) Cofactors – especially NADH in oxidoreductase enzymes.  Recycling of NADH.  

 

(f) Kinetic resolution and dynamic kinetic resolution.  

 

(g) Directed evolution for the development of bespoke biocatalysis.  

 

(h) Enzyme applications.  

 

  • Hydrolase enzymes – lipases, esterases, proteases etc. with specific examples and mechanism.  

  • Lyases – e.g. Aspartase, tyrosine-phenol lyase  

  • Isomerases – e.g. glucose isomerase  

  • Transferases – e.g. aminotransferases, PLP as cofactor  

  • Ligases  

  • Oxidoreductases – dehydrogenases, oxidases, oxygenases, peroxidases  


CHT225: Practical Catalytic Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT225
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Jonathan Bartley
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module trains students to use a variety of research methods and techniques applicable to catalysis, thus equipping them with a range of skills, which they can apply to modern laboratory and industrial scale research.

The module will comprise practical work in each of the three delineated areas of catalysis – namely heterogeneous catalysis, homogeneous catalysis and biocatalysis

On completion of the module a student should be able to

Knowing(these are things that all students will need to be able to do to pass the module):

  • use equipment appropriate to the experiments in a safe and correct way;
  • obtain and act upon safety and hazard information for chemicals;
  • use and apply some of the techniques necessary for the preparation of heterogeneous catalysts;
  • use and apply simple techniques for the isolation of an enzyme from a natural source and assess its concentration;
  • prepare selected organometallic complexes and employ them as homogeneous catalysts;

Acting(Performance in this area will enable students to achieve more than a basic pass):

  • assess the activity of different types of catalyst isolated from various sources;
  • interpret experimental data and make deductions in the light of an existing model for a system;
  • put new experimental data into the context of what was already known;

Being(Performance in this area will enable students to achieve more than a basic pass):

  • appreciate the context of the experiments and research undertaken;
  • prepare a concise account of previous work on a topic from a survey of the literature.

How the module will be delivered

This module will be practical based and so will be delivered as a series of experiments taking place either in the School’s teaching laboratories or in some of the research laboratories.

Skills that will be practised and developed

Discipline Specific (including practical) Skills:

  1. The student will acquire new skills in the area of practical synthesis within a modern laboratory environment.
  2. There will be enhancement of previous spectroscopic knowledge through further study and experiment application.

Transferable Skills:

  1. Experience of team working;
  2. Experience of presenting and assessing data in front of a critical audience;
  3. Writing an account of research in a format suitable for publication in a peer reviewed journal.

How the module will be assessed

The module will be assessed by a combination of written reports and oral presentations.

Assessment Breakdown

Type % Title Duration(hrs)

Syllabus content

Preparation and analysis of heterogeneous catalysts – this will include a literature investigation with students giving an oral presentation of their findings.

Extraction and analysis of biocatalysts from natural and commercial sources.

Preparation and analysis of homogeneous catalysts.


CHT226: Bioinorganic Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT226
External Subject Code 101043
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Professor Ian Fallis
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

 

Many key processes in biology are enabled by metal ions such as calcium, iron, copper, and zinc. In this module the biological functions of a wide range of elements are examined with a particular focus upon the functions of metal ions and their catalytic roles in biology.  

 

The module will correlate the fundamental coordination chemistry of metal ions to the wide range of redox, Lewis acidic and structural roles they play in biological structures.  

 

The roles of metal ions in selected important drugs will also be explored.  

 

On completion of the module a student should be able to

  • Describe the range of functions of metal ions in biological systems.  

  • Classify metalloenzymes by reaction type and illustrate with relevant examples.  

  • Classify the types of metalloproteins and co-factors that incorporate transition metal and main group ions.  

  • Explain from an evolutionary perspective the need for transition metal ions in biological systems.  

  • Identify the mechanisms of metalloenzyme promoted chemical transformations.  

  • Explain and illustrate the mode of action of metal containing drugs.  

How the module will be delivered

 

A blend of on-line learning activities with face-to-face small group learning support and feedback.  

 

Content will be delivered primarily using lectures (22 h across one semester, equating to two lectures per week). In addition, lectures will include worked problems and informal ad hoc formative tests.  

 

This will address the learning outcomes, while examples presented will show you how they may also demonstrate their achievement.  

 

 Workshops (3 x 1 hour, one formative, two summative) will be used to enhance and assess the basic knowledge from the lecture material.  

 

Tutorials (2 x 1 hour, formative) will allow tutors to monitor and guide your progress in meeting all learning outcomes. 

 

Skills that will be practised and developed

Chemistry-Specific Skills: 

 

  • Classification of complex bioinorganic systems.  

  • Analysis and understanding of the mechanisms in bioinorganic chemical systems;  

  • Correlation of fundamental chemical properties of the elements with their roles in biological systems.  

 

Employability skills: 

 

This module is delivered and aligns with the following University Graduate Attributes: 

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Graduate Attributes – Assessment:    

  

 Written Assessment                             30% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 Exam                                                 70% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 3. Ensure healthy lives and promote well-being for all at all ages  

Goal 15. Protect, restore, and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss  

How the module will be assessed

 

Formative and Summative Assessment: The three workshops take the form of multiple-choice tests to be taken in the class. Two will be assessed summatively, and feedback provided during the workshop. Tutorials will be used as reading periods to allow you to absorb course material and raise questions.  

Summative assessment: A written exam (2 h) will test the student’s ability to demonstrate their knowledge and understanding of the syllabus content, and their ability to apply the techniques/concepts covered to unseen problems. The coursework will allow you to demonstrate ability to use electronic and printed resources to locate and understand relevant information. Marks will reflect the extent to which you have met the module learning outcomes shown above.  

  

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.  

 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session.  

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 30 Workshop N/A
Exam - Spring Semester 70 Bioinorganic Chemistry 2

Syllabus content

The placement experience will be undertaken in the industrial or university host approved by the placement scheme coordinator. The main feature will be a substantial project on a chemical sciences topic determined by the host. This will be carried out on a time scale appropriate for the particular placement but is expected to take about 800 hours of student time, including all literature work, project work, preparation of presentation and written report. 

 

For academic placements, it is expected that all of the nominal 800 hours will be spent on the project at the host. For the industrial placements, the aim is for a similar arrangement, but it is recognised that the nature of the host’s work may require this to be modified and directed work related to the host’s business may take up some of the time, though a substantial independent and original project must be included.  

 

The main report will be supplemented by a short placement review, describing the particular environment of the placement - aspects of cultural differences in teaching and learning methods in host university, skills development during the placement, business aspects of the company for industrial placements.  

 

Regular contact will be maintained throughout, primarily through the personal tutor, with involvement by the placement coordinator, as necessary.  


CHT228: Asymmetric Synthesis of Pharmaceuticals and Natural Products

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT228
External Subject Code 100422
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Professor Thomas Wirth
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module consists of a range of examples exposing the students to sophisticated methods in stereoselective synthesis. 

Building on required previous modules such as CH4303, advanced methods for stereo control in total synthesis, preparation of enantiomerically pure drug molecules, development of stereoselective reactions as well as the introduction of various enabling technologies will be the main focus of this module. 

Throughout, the ability to extract stereo chemically relevant information from complex syntheses will be a major focus.  

On completion of the module a student should be able to

  • Appreciate the range of synthetic methods available to prepare enantiomerically pure molecules.   

  • Know the strategies and reagents required to generate and implement new stereochemical elements within target-oriented syntheses.   

  • Identify key problems in both small-scale academic synthesis and large-scale industrial synthesis of stereo chemically pure compounds.   

  • Identify different reaction technology equipment and summarise the key criteria to consider before using it.   

  • Understand the principles and strategies of stereoselective alkene functionalization.   

  • Understand main principles in the use of enabling technologies and related industrial issues together with application to target molecules.   

  • Recognize where organocatalysis can be applied in synthesis and which strategies in this area are available.   

  • Explain when alternative tools and techniques may offer significant benefit to a desired reaction outcome.  

How the module will be delivered

10 two-hour lectures, supplemented by 2 1-hour class tutorials. 

Skills that will be practised and developed

 

Chemistry-Specific Skills: 

 

  • Ability to analyse stereochemical problems and provide synthetic meaningful solutions.   

  • Assess and solve problems in asymmetric synthesis together with their theoretical background and any strengths or weaknesses associated with them.   

  • Identification of chemical problems which can be solved by involving enabling technologies.  

 

Employability skills:     

   

This module is delivered and aligns with the following University Graduate Attributes:     

   

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

   

Graduate Attributes – Assessment:    

  

Workshop                        30% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Exam                               70% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 Sustainable Development Goals:      

   

This module is delivered and aligns in working towards the following Sustainable Development Goals:    

  

Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture 

Goal 3. Ensure healthy lives and promote well-being for all at all ages 

Goal 12. Ensure sustainable consumption and production patterns 

How the module will be assessed

Written exam and Workshop. 

The workshop and the written exam will focus on different topics due to the timing of these events. They will enable the students to demonstrate that they have achieved the learning outcomes.  

Marking criteria will involve the validity of the provided answers and the ability of the student to handle unknown material.  

Further details (dates) are found in the assessment map.  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session.  

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 30 Written Workshop N/A
Exam - Autumn Semester 70 Asymmetric Synthesis of Pharmaceuticals and Natural Products 2

Syllabus content

Alkene Functionalisations   

Introduction to advanced asymmetric synthesis. Stereoselective functionalisations of double bonds: Briefly revising Sharpless AE and ADH, Jacobsen (year 3), then introduction of other electrophilic reagents including selenium- and iodine-based compounds.  Applications in total synthesis and the synthesis of bioactive compounds will be discussed.   

 

Enabling Tools for Organic Synthesis   

As synthesis moves into the modern era so too does the way in which chemists can conduct chemistry. This part of the course introduces the technical considerations needed for using existing and futuristic synthesis tools such as microwave reactors, photochemical reactors, electrochemistry, and continuous flow chemistry. Important factors are being considered when conducting reactions using these methods, there will also be a strong focus on the types of synthetic chemistry suited to these modes.   

 

Organocatalysis   

Organocatalysis is defined as the use of a sub-stoichiometric amount of an organic molecule to accelerate the rate of a chemical reaction. This part will serve as an introduction to the diverse and exciting field of organocatalysis and will specifically cover: a historical perspective; benefits and limitations; catalyst synthesis; covalent and non-covalent organocatalytic activation modes; selectivity (regio-, diastereo- and enantiocontrol); applications within industry; applications towards the synthesis of biologically active compounds.  


CHT229: Advanced Techniques in Organic and Biological Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT229
External Subject Code 100422
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Niklaas Buurma
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

In this module, the application of biophysical and computational techniques to study interactions in biological and medicinal chemistry research will be discussed. 

Students will appreciate what information can be gained from each technique and learn how to plan experiments and interpret the resulting data. 

On completion of the module a student should be able to

  • Decide which technique, or combination of techniques, is most appropriate to study interactions between biomacromolecules and between biomacromolecules and small molecules. 

  • Decide which technique, or combination of techniques, is most appropriate to obtain structural information for interactions between biomacromolecules and between biomacromolecules and small molecules. 

  • Interpret the results from biophysical and computational techniques. 

  • Critically assess the validity of results from biophysical and computational techniques on the basis of an understanding of the physical basis of these techniques. 

How the module will be delivered

The module is taught using a combination of online recordings, 10 2-hour interactive workshop-style lectures, and a 2 one-hour tutorials, as detailed in the weekly module map. 

The online recordings present the required theory and students are required to watch the recordings before the corresponding interactive workshop-style lectures. 

The interactive lectures then apply the theory as presented in the recordings to exam-style problem-solving exercises. 

The module also includes a summatively assessed open-book exam-style in-class workshop. 

Skills that will be practised and developed

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Graduate Attributes – Assessment:    

  

 Class Test                             30% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 Exam                                    70% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 3. Ensure healthy lives and promote well-being for all at all ages 

How the module will be assessed

The module will be assessed through an open-book class test and an exam.

The summatively assessed open-book class test assesses the student’s ability to decide which technique, or combination of techniques, is most appropriate to study interactions between biomacromolecules and between biomacromolecules and small molecules; decide which technique, or combination of techniques, is most appropriate to obtain structural information for interactions between biomacromolecules and between biomacromolecules and small molecules; interpret the results from biophysical and computational techniques; critically assess the validity of results from biophysical and computational techniques on the basis of an understanding of the physical basis of these techniques. The open-book class test also serves as a practice exam.

The exam assesses the student’s ability to decide which technique, or combination of techniques, is most appropriate to study interactions between biomacromolecules and between biomacromolecules and small molecules; decide which technique, or combination of techniques, is most appropriate to obtain structural information for interactions between biomacromolecules and between biomacromolecules and small molecules; interpret the results from biophysical and computational techniques; critically assess the validity of results from biophysical and computational techniques on the basis of an understanding of the physical basis of these techniques. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)

Syllabus content

All content is mandatory.  

 

Spectroscopic techniques 

Principles of UV-visible, fluorescence, FRET, circular dichroism, vibrational circular dichroism spectroscopies as used in biophysical studies. The use of temperature-dependent spectroscopy to obtain thermodynamic data. Data acquisition and interpretation. 

 

Solution calorimetric techniques 

DSC and ITC. Data acquisition and interpretation. 

 

Other techniques 

Further biophysical techniques, including surface plasmon resonance (SPR); SPR instrumentation; SPR methods for determining equilibrium constants and kinetics; biolayer interferometry; SwitchSENSE; Mass spectrometry for study of biomolecules; electrochemical techniques and other modern techniques in biophysical chemistry. 

 

Data analysis 

Applications of biophysical techniques to the study of biomolecular structure and interactions, including data analysis and estimation of error margins 

Structure-based methods 

Computer-based methods for docking small molecule ligands into protein binding sites; Introduction to developing and validating scoring functions to determine qualitative ligand binding free energies. 

 

Computing the energies of protein/ligand complexes using empirical force field methods; Molecular dynamics simulations and computer-based conformational sampling methods to obtain quantitative estimates of ligand binding free energies. 

 

Introduction to X-ray crystallography and cryogenic electron microscopy for acquiring atomic details of biomolecular structures and their complexes with small molecule ligands; overview of 1D and multi-dimensional Nuclear Magnetic Resonance (NMR) methods to determine the structure of biomolecules and protein/ligand complexes. 

 


CHT231: Advanced Magnetic Resonance Spectroscopy: Principles and Applications

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT231
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Professor Damien Murphy
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

Magnetic resonance techniques, including NMR and EPR, are extremely powerful tools for investigating the structure and dynamics of molecules. 

This module offers the student the opportunity to study the underlying physical principles of NMR and EPR, primarily in the solid state, and the surrounding magnetic interactions that determine the appearance of the experimental spectra. 

Coverage of conventional principles in magnetic resonance, showing how the resonance frequency of a nucleus (or electron) is affected not only by the applied field but also by the electronic environment and surrounding nuclei, will be presented to the students. 

A more advanced EPR technique called ENDOR, where EPR and NMR transitions are simultaneously pumped and then monitored, will also be introduced in both liquid phase and solid phase conditions. 

Particular emphasis will be devoted to the analysis of NMR and EPR spectra in the solid state.  

The anisotropic interactions responsible for the broad and more complex spectral line shapes experienced in the solid state (compared to the isotropic profiles experienced in the liquid state) will be treated using a series of examples. 

The advanced methodology of angular selective ENDOR, used to analyse and extract structural information for paramagnetic species in frozen solution, will also be covered. 

On completion of the module a student should be able to

  • Explain the origin of the Zeeman interaction; 

  • Demonstrate the importance of spin angular momentum and the spin magnetic moment in magnetic resonance spectroscopy; 

  • Describe the behaviour of nuclear and electron spins in an applied magnetic field; 

  • Identify the role of spin angular momentum as the foundation in NMR and EPR; 

  • Describe the importance of various magnetic interactions, such as spin-spin coupling, as a vital source of information;  

  • Explain the nature of anisotropic interactions in the solid state, and how they dictate the shape of the spectra; 

  • Demonstrate how various magnetic interactions including electron Zeeman interactions, zero field splitting, hyperfine interactions, nuclear Zeeman interactions, and quadrupole interactions, can be extracted from the EPR spectrum; 

  • Know how dynamic, as well as structural information can be accessed in the solid state, and identify the importance of the timeframe of the NMR techniques in dynamic studies; 

  • Discuss the approaches taken to record NMR spectra in solid state; 

  • Describe how the ENDOR technique is performed and the role of saturation and relaxation phenomena in acquiring ENDOR signals with optimal amplitudes; 

  • Describe how the angular selective ENDOR methodology is applied to study paramagnetic systems in the solid state. 

How the module will be delivered

A blend of on-line learning activities with face-to-face small group learning support and feedback. 

The module will be delivered in 10 two-hour lectures, supplemented by 4 one-hour class tutorial 

Skills that will be practised and developed

Chemistry-Specific Skills: 

 

  • Link formal equations to observed NMR/EPR spectra; 

  • Interpret experimental observations in terms of the molecular and structural properties of the system; 

  • Select appropriate techniques for determination of structure in solution or solid state for a range of chemical situations; 

  • Assess the advantages/disadvantages of the different techniques for each particular purpose and chemical problem; 

  • Appreciate the steps involved in the analysis of modern magnetic resonance experiments; 

  • Explain how NMR/EPR may be used to study problems of general chemical interest; 

  • Use qualitative arguments to develop a theoretical description of magnetic resonance phenomena; 

  • Use quantitative measurements to verify or disprove theoretical models. 

 

Employability skills:    

This module is delivered and aligns with the following University Graduate Attributes: 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

Graduate Attributes – Assessment:    

 

Written Assessment                 30% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 Exam                                        70% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

Sustainable Development Goals:     

  

This module does not align with any of the Sustainable Development Goals, but its applications will contribute towards all in part.   

How the module will be assessed

The module will be assessed by a combination of coursework (30%) and written examination (70%). 

The single assessed piece of open-book coursework, containing questions based on both the NMR and EPR components of the module, will be delivered during the course. 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 30 Written Assignment N/A
Exam - Spring Semester 70 Advanced Magnetic Resonance Spectroscopy: Principles and Applications 2

Syllabus content

Foundations in Solid State NMR: This part of the course will provide an introduction to solid-state NMR spectroscopy, focusing initially on relevant theoretical background and experimental techniques.   

The discussion of background theory will highlight the significant differences between solid-state NMR and liquid-state NMR, focusing on the main anisotropic NMR interactions that are important in the solid state.   

  

The discussion of experimental strategies will then focus on the techniques for recording:   

  

(a) broad-line solid-state NMR spectra (in which the anisotropic NMR interactions are studied)  

(b) high-resolution solid-state NMR spectra (in which the aim is to record narrow-line spectra that resemble those recorded in liquid-state NMR).   

  

The course will then build upon these foundations by discussing the applications of solid-state NMR to investigate structural and dynamic properties of solids, highlighting the scope and limitations of different types of solid-state NMR technique.   

  

Several recent examples of the application of solid-state NMR to solve problems in solid-state and materials chemistry will be presented.   

  

Students attending the course will emerge with an appreciation of the types of problem that can be tackled successfully by solid-state NMR, and the particular NMR technique (or combination of techniques) is most suitable for investigating each type of problem.  

  

Foundations of liquid and solid state EPR & ENDOR: The basic principles underlying the EPR technique will be covered, including coverage of the form of the spin Hamiltonian for systems in the solid state. This will initially be treated for the liquid phase, before considering the more complex case of the solid-state Anisotropy  

  

Anisotropy of the g and A hyperfine tensors, and the role of symmetry as manifested in the g/A frame will then be presented to the students.   

  

The theory and applications of angular selective ENDOR, based on the angular dependency of the EPR spectra, will also be covered in the lectures. Examination of the profiles of EPR spectra in the solid state will then be covered.   

  

The lectures will then cover the theory of ENDOR, with particular emphasis on the saturation and relaxation pathways important in this technique.   

  

The role of angular selection as a means of determining structural information for paramagnetic centres in the solid state will then be given.   

  

Examples of systems with low g anisotropy (no hyperfine interaction) leading to powder ENDOR patterns, and subsequently axial g anisotropy and axial hyperfine, leading so ‘single crystal-like’ ENDOR patterns will then be investigated.   

  

The students will then appreciate the experimental approaches taken to obtain EPR and ENDOR spectra of paramagnetic centres in the solid state (primarily in frozen solution) and the general methodologies subsequently involved in the analysis and understanding of the experimental data.   

  

Numerous examples of how to interpret solid state EPR / ENDOR spectra will be covered during the course.  


CHT232: Key Skills for Postgraduate Chemists

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT232
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Professor David Willock
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module will provide you with the opportunity to review chemistry topics that underpin the MSc programme that you are studying.  

 

Topics offered will include organic chemistry, inorganic chemistry, physical chemistry, theoretical concepts, and analytical techniques.  

 

The topics assessed will be tailored to your personal needs and reflect the material required to help give you the basis to undertake your MSc programme.  

On completion of the module a student should be able to

 

  • Strengthen understanding of chemical concepts required at the MSc level of study. 

  • Use the ideas covered in the topics selected to analyse data from the relevant areas of chemistry. 

  • Seek out background information from a variety of resources including textbooks, on-line information, and primary literature in relevant areas. 

  • Use information from a variety of sources to critically analyse chemical data across a number of topics. 

  • Link the background topic information provided in this module with the advanced discussion used in other modules of your MSc. 

 

How the module will be delivered

 

The module content will be delivered via face-to-face lectures that introduce key concepts in Chemistry and provides resources for further study.  

 

Each topic will provide summative assessment to help guide you in your independent study. 

 

You will attend 7 hours of lectures including 2 hours of general direction on the structure of the module and 5 hours of topic specific material. You will work through independent study to solve assessments set for each topic.  

 

The topics you take will depend on the MSc programme on which you are enrolled with some topic choice available for some MSc programmes. You will study the 5 topics which best link to your MSc programme. 

 

The week-by-week delivery schedule and timing of assessment tasks will be described in the module map.  

 

Skills that will be practised and developed

Skills covered in this module are directly in line with the Graduate Attributes used across the University. 

 

Academic Skills: 

 

  • This module will encourage you to take control of your academic study, strengthen your critical thinking and independent learning skills. Including obtaining information from the scientific literature.  

  • You will be encouraged to undertake your studies in collaboration with your classmates and so develop communication and collaborative working skills. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

  

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Understand organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Graduate Attributes – Assessment:    

  

 Coursework                         100% 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Understand organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

 Reassessment                     100% 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Understand organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 6. Ensure availability and sustainable management of water and sanitation for all  

Goal 7. Ensure access to affordable, reliable, sustainable, and modern energy for all  

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, and decent work for all

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development 

How the module will be assessed

The module will begin with a series of on-line tests allowing you to review your current understanding of areas of chemistry considered background knowledge for our MSc programmes. On the basis of the results and the recommendation of the MSc Programme you will decide which topics to take in order to support their learning. 

 

The summative assessment for the module will be through topic-based coursework assignments in the topics. Each topic will contribute equally so that the 5 topics each student selects will contribute 20% of the module mark. The marking scheme will assess the student’s understanding of the material introduced by each topic.  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

For students not gaining a pass mark overall new assessments will be set in topics with coursework marks under 50%. 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 100 Coursework N/A

Syllabus content

The module provides topics to study that give background level understanding of key ideas required at the MSc level in Chemistry. These topics cover the areas required to underpin each of the MSc programmes in Chemistry. 

 

You will take the equivalent of 5 of these topics delivered according to the module map for the module. 

 

 


CHT235: Analytical and Structural Techniques in Chemical Biology

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT235
External Subject Code 100948
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Louis Luk
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

 

Chemical biology plays a crucial role in advancing our understanding of biology and its applications in bioindustries and medicine.  

 

This module provides a comprehensive overview of structural and analytical techniques central to chemical biology research, enhancing your understanding of technologies for preparing and characterizsing proteins, nucleic acids, and low molecular weight metabolites.  

 

A variety of chemical biology methods will be discussed, from extracting chemically relevant information from biomacromolecular structures to the genetic modifications of organisms, underlying the development of critical bio-analytical skills and ethical reasoning. 

 

You will explore fundamental techniques such as recombinant gene expression and chemical protein synthesis. Key applications in antibody-based immunohistochemistry, drug development in medicinal chemistry, and genetic engineering using CRISPR-Cas9 will be discussed.  

 

The module will guide you in analysing and interpreting experimental data, emphasising their practical relevance in medical development, and raising awareness of related ethical and social issues. 

 

A key aim of the course is to enhance your reflective learning through problem-solving exercises. Creativity will be encouraged by discussing cutting-edge research, and resilience will be developed through presenting novel techniques recently reported in scientific literature.  

 

This course both provides a solid foundation in chemical biology techniques and equips you with critical thinking and communication skills. 

 

On completion of the module a student should be able to

  • Devise experimental strategies to solve problems in chemical biology, focusing on polypeptide and nucleic acid chemistry, promoting innovation and adaptability, skills valuable in various professional roles;   

  • Select strategies for characterising proteins, nucleic acids, and low-molecular weight molecules, and to critically analyse experimental data, nurturing analytical thinking; 

  • Choose strategies for genome modification and its applications, whilst taking ethics and responsible research into considerations;  

  • Use structural and analytical techniques to answer key questions in chemical biology and medicinal chemistry, further promoting critical thinking and problem-solving skills, skills essential to diverse career paths; 

  • Identify potential the applications of chemical biology in medicine development, enhancing their real-world implications; 

  • Present new techniques extracted from scientific literature, enhancing independent learning, and keeping abreast of the latest developments in the field 

How the module will be delivered

 

The module will be delivered primarily using lectures (12-hours) where the principles of chemical biology techniques will be introduced including case studies from the literature.  

 

In addition, lectures will include worked problems and informal ad hoc formative activities. Workshops (one formative, one summative) will be used to enhance and assess problem-solving and literature-searching skills. 

 

Skills that will be practised and developed

Chemistry-Specific Skills: 

 

  • Actively engage in applying key concepts ranging from recombinant protein preparation and chemical protein synthesis to nucleic acid engineering. 

  • Develop the crucial skill of proposing appropriate techniques to address various chemical biology questions, fostering their critical thinking and problem-solving abilities. 

  • Proposal of polypeptide synthesis schemes, the analytical characterization of proteins and nucleic acids, and the use of analytical techniques for the detection, quantification, and activity assessment of proteins and nucleic acids.  

  • Assess protein expression levels using advanced analytical technologies and employ enzymes for genome sequence modification, along with mastering the techniques for their characterization. 

  • Enhance their research skills by searching for relevant experimental techniques in scientific literature. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

 Oral Presentation                      30% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 Exam                                         70% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 Resit Exam                               100% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 2: End hunger, achieve food security and improved nutrition and promote sustainable agriculture. 

 

Goal 3: Ensure healthy lives and promote well-being for all ages. 

 

Goal 5: Achieve gender equality and empower all women and girls. 

 

Goal 9: Build resilient infrastructure, promote inclusive and sustainable industrialisation and foster innovation. 

 

Goal 17: Strengthen the means of implementation and revitalise the Global Partnership for Sustainable Development. 

 

How the module will be assessed

Formative assessment: The first workshop will be assessed formatively, and feedback provided either orally or in written form. This will give you an opportunity to revise the module content and to apply it to deduce and propose solution for chemical biology-based questions. 

 

Summative assessment: A summatively assessed workshop in the form of an oral presentation will allow the student to demonstrate their ability to use electronic resources to locate relevant information in the literature to provide a new chemical biology technique for a contemporary research topic. 

 

A written exam (2-hours) will test the ability to outline experimental approaches for the preparation and characterisations modified polypeptides and genome and/or propose and interpret chemical biology experiments. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment are only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

Please provide information to the student about the opportunity for reassessment, should they fail the Module. You should explain the format that reassessment.  

 

If the reassessment is in a different format to the original assessme

Assessment Breakdown

Type % Title Duration(hrs)
Presentation 30 Oral Presentation N/A
Exam - Spring Semester 70 Analytical and Structural Techniques in Chemical Biology 2

Syllabus content

 

  • Sustainable production of labelled polypeptides with necessity for precision, efficiency, and adaptability in biomedical research (biotherapeutics such as antibody-drug conjugates); 

  • Recombinant Approaches for hydrophobic/isotopically labelled polypeptides and their applications in antibacterial reagents; 

  • Characterization techniques including SDS-PAGE, HPLC, mass spectrometry; 

  • Solid phase peptide synthesis, chemical ligation, orthogonal protecting group chemistry for the production of ubiquitinylated histone with its implications in cancer biology research; 

  • Small Molecule Metabolites Characterization through utilisation of technologies including reporter systems, Western Blot, PCR; 

  • Understanding metabolic pathways and interactions; 

  • Efficient Enzymatic Systems for Genome Modification including technologies, such as zinc finger nucleases, TALENs, CRISPR-Cas9. 

 


CHT237: Bio-imaging Applications of Coordination Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT237
External Subject Code 100948
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Professor Simon Pope
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

The module consists of three main topics associated with the application of inorganic coordination compounds to biological and biomedical imaging: luminescence, magnetic resonance and radio imaging will be covered. 

The module will provide a technical background to each of the imaging modalities and then focus upon the use and application of metal coordination compounds in each discipline, including modern commercial/clinical settings. 

Aspects of synthesis and molecular design will be described, and the ability to rationalise the relationship between complex structure and function (including the biological context) will be a fundamental focus. 

 

On completion of the module a student should be able to

  • Describe the fundamental concepts and principles that underpin fluorescence imaging, magnetic resonance imaging and radio imaging techniques. 

  • Discuss the physical concepts that drive the ligand design and choice of metal ion for a given imaging application. 

  • Understand the synthetic chemistry pathways to selected ligands and complexes. 

  • Demonstrate a critical awareness of the strategies for metal complex biocompatibility and stability in vitro and in vivo. 

How the module will be delivered

This module will be delivered in ten two-hour lectures, supplemented by three 1-hour class tutorials. Three staff will teach, each delivering the three subtopics. 

A summative workshop (30%) will require a detailed critical analysis of a literature work based on a particular class of imaging agent.  

Skills that will be practised and developed

Academic skills: 

 

Understanding what kind of information is provided by different imaging techniques 

Interpret complex scientific information and relate to properties of different classes of imaging agent 

Develop effective skills focussed upon reviewing primary literature and extracting relevant information 

 

Chemistry-specific skills: 

 

  • Understand the underpinning fundamental principles of optical, MRI and radio imaging 

  • Be able to interpret relate to molecular design of imaging agents to target applications 

  • Be able to analyse physical data and apply in problem solving  

 

Employability skills: 

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

  •  

 

Graduate Attributes – Assessment:    

  

 Written Assessment                        30% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 Exam                                             70% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 

 Resit Exam                                  100% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:  

Goal 3. Ensure healthy lives and promote well-being for all at all ages   

  

How the module will be assessed

Summative assessment: workshop is a take-home assessment that requires engagement and analysis of the primary literature on a responsive bimodal imaging agent – it is a word count limited written report. This will assess a student’s ability to use electronic data bases and locate relevant information and critically review the primary literature. This will assess a student’s knowledge of molecular design and a deep understanding of the physical parameters that describe physical properties and dictate the biological application.  

 

A written exam (2 hour, 70%) will test the student’s ability to demonstrate their deep knowledge and understanding of the syllabus content, and their ability to apply the techniques/concepts covered to unseen problems.  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Students who are permitted by the Examining Board to be reassessed in this module during the same academic session will sit an examination (2-hour) during the Resit Examination Period. 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 30 Written Assignment N/A
Exam - Autumn Semester 70 Bio-imaging applications of coordination chemistry 2

Syllabus content

Optical imaging using Luminescence  

 

Background on confocal fluorescence microscopy for cellular imaging 

Background on photo physics – Stokes shift, Jablonski diagrams, time resolved vs steady state measurements, quenching pathways, types of emission, tuning emission through ligand design. 

 

Types of TM-based luminophore including descriptions of ligand design, synthesis, photo physics and applications to imaging and biocompatibility 

 

                  - d6 Ru(II), Re(I), Ir(III) complexes 

 

Discussion of variants for organelle targeting and structure/function relationships. 

 

Types of lanthanide(III)-based luminophore including descriptions of ligand design, synthesis, photo physics and applications to imaging and biocompatibility 

 

                  - visible emission using Eu(III) and Tb(III) 

                  - near-IR emission using Nd(III) and Yb(III) 

 

Magnetic Resonance Imaging and Contrast Agents 

 

Background on magnetic resonance imaging. The history and the basic principles of the experiment. 

Background on the fundamental properties and design of T1 and T2 contrast agents. 

Types of complexes used for T1 contrast- lanthanide, transition metal and organic molecules. 

Types of complexes used for T2 contrast- lanthanides and transition metal clusters. 

Using CEST and PARACEST for imaging. 

Assessing new contrast agents –solubility, stability and the NMRD. 

Dual mode imaging and the theranostic approach. 

 

Gamma Radio-Imaging via SPECT and PET  

 

Background to gamma imaging – physical basis of the techniques, data capture and imaging 
Single Photon Emission Tomography (SPECT) 
Positron Emission Tomography (PET) - 
general properties of PET/SPECT isotopes, half-lives, imaging resolution, biological matching 

Background to functional imaging vs. structural imaging – 
organ perfusion imaging, inflammation imaging, bone imaging (SPECT) 
biologically active PET probes (FDG, F-DOPA, etc.) 

Ligand design for SPECT and PET isotopes and metal complexes – 
Tc complexes for SPECT 
Ga, Cu, Zr, Y complexes in PET 

 

Essential Reading and Resource List 

 

References to the primary literature will be given throughout and students will be expected to utilise WoK to access supporting information to the lecture notes. 


CHT238: Industrial Catalysis

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT238
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Jonathan Bartley
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module aims to give students a perspective on the current state of industrial heterogeneous catalysis processes.

The role of catalysts and their uses in energy and environmental applications and sustainable manufacturing applications will be described and discussed.

This module will include lectures from industrialists as well as academics to give the students an understanding of the importance of industrial catalytic processes and how these fit with commercial and societal needs.

On completion of the module a student should be able to

  • Students should be able to demonstrate the principles underpinning the use of catalysis for industrial processes
  • Explain the requirements and processes involved in commercialising an industrial process
  • Locate, synthesise and evaluate information from multiple sources
  • Retrieve, critically evaluate and communicate orally and in writing information from a variety of sources (literature, electronic databases).
  • Draw conclusions and propose hypotheses based on evaluation of the information obtained information.

How the module will be delivered

The module will consist of 6 × 2 hour lectures from different speakers involved in various aspects of catalysis in industry and academia. Students will have the opportunity to meet with the speakers to discuss the topic in more detail. Students will be expected to supplement these lectures with self-directed research of texts, web resources, specialist reviews and peer-reviewed literature. Students will be provided with guidance by a module tutor at two scheduled individual meetings.

Skills that will be practised and developed

Students will need to research and evaluate facts, ideas and opinions from multiple sources including lectures, personal discussions, specialist periodicals and books. Students will develop their ability to summarise and critically review potentially contradictory or incomplete information and opinions. Students will practice presenting complex ideas and arguments orally and through a written report to a professional standard with the use of appropriate IT.

How the module will be assessed

 

Students will be required to give a short oral presentation on a chosen topic related to critical reviews/themes of industrial heterogeneous catalysis and will be assessed on their choice of content, clarity, logical structure, performance and ability to answer questions. The exact topics of the presentation will be chosen by students with the guidance of the course or module tutor and will be related to the topics covered in the lectures.

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:

 

The module will be reassessed through additional written coursework and/or presentations over the summer. 

Assessment Breakdown

Type % Title Duration(hrs)

Syllabus content

Mandatory content

The course will cover a range of industrial chemical processes such as petrochemical processes, biorenewable processes, oxidation, hydrogenation and catalysis for environmental control.

 

Optional content

Students will be required to develop greater knowledge and understanding of selected areas for their chosen topic. The following is a representative, but non-exhaustive list of possible topics.

  1. Gold catalysts for the production of vinyl chloride monomer
  2. Catalysis for automotive applications
  3. Biofuels from biomass
  4. Steam reforming
  5. Methanol synthesis
  6. Assymetric hydrogenation

CHT239: Advanced Materials

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT239
External Subject Code 100225
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Jonathan Bartley
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

The module aims to develop an understanding of the synthesis, characterization, simulation, and applications of specific advanced materials in the modern chemical environment.  

The course will cover semiconductor materials; material surfaces and nanoparticles; colloidal systems in industry and healthcare; heterogeneous catalysis with nanoparticles and bulk catalysts; and the modelling, synthesis, and characterisation of these advanced materials. 

On completion of the module a student should be able to

  • Systematically explain how different methods for synthesising and formulating advanced materials can impact on their performance in different applications.   

  • Evaluate and predict key properties of materials based on modelling and characterisation data.  

  • Analyse experimental/characterisation/modelling data for different advanced materials to probe the material properties and establish an understanding between structure, composition, and chemistry.  

  • Critically assess literature relating to advanced materials properties and applications.  

  • Relate computational and experimental information on catalytic systems to identify the relationship between structure and performance.  

How the module will be delivered

You will receive course content delivered primarily using face to face lectures. The course consists of 10 x 2-hour lectures during the Spring semester, with approximately 3 lectures a week for 3-4 weeks.

Lectures may include some worked problems and informal formative questions to support principles introduced. These will help you to address the learning outcomes and provide opportunities to apply knowledge and develop understanding. 

The lecture schedule will follow the module map published prior to the start of the module. Lectures will be recorded and will be available following the live sessions. A combination of lecture slides and additional supporting notes will be available for you prior to the face-to-face lectures. 

Lecture material will be supported by four formative workshops that will focus on problem solving based on material from lectures and discussions around the course content. These formative workshops will provide you with guidance and support for the assessed coursework and examination.  

Skills that will be practised and developed

Skills developed through formal module learning outcomes and summative assessment include:  

  

Academic Skills:  

 

  • Assessments require independent critical thinking to analyse problems and the ability to communicate complex information. 

 

  • In the summative workshop exercise you will analyse a research article, drawing out the key information and exercise critical judgement in evaluating sources of information. 

 

 

Chemistry-Specific Skills: 

 

  • You will develop chemistry specific skills, focussed on applying ideas from fundamental physical and inorganic chemistry and apply innovative thinking to understand how these can be applied to the use of advanced materials for different applications.  

 

  • You will develop intellectual curiosity and develop new understanding of how properties of materials can be controlled by tuning the synthesis procedure and how advanced characterisation methods can be used to help derive structure activity relationships.  

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:   

  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 

Graduate Attributes – Assessment:    

  

Coursework                       30% 

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Exam                                 70% 

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:  

 

Goal 6. Ensure availability and sustainable management of water and sanitation for all

Goal 7. Ensure access to affordable, reliable, sustainable, and modern energy for all

Goal 12. Ensure sustainable consumption and production patterns  

Goal 13. Take urgent action to combat climate change and its impacts        

Goal 14. Conserve and sustainably use the oceans, seas, and marine resources for sustainable development 

How the module will be assessed

Summative assessment will take the form of a written examination and a written piece of coursework.  

A two-hour closed book written exam will test your ability to demonstrate knowledge and understanding of the syllabus content, and your ability to apply the techniques and concepts covered to problems solving that are related to familiar and unseen examples.  

The summative coursework will allow you to demonstrate your ability to review and evaluate research from the literature through the preparation of a short-written report (2 pages). You will be able to choose between papers relating to colloids, nanoparticles and catalysis for the coursework and will need to identify how different characterization techniques can be used to gain understanding of materials. You will receive feedback on your work before the written exam. 

Your learning will also be supported by the formative workshops, and feedback provided either orally or in writing during and after the sessions. There will be a focus on supporting problem solving based on applying knowledge and understanding of materials properties for different applications.  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Reassessment will follow the same format as the original component of the assessment. 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 30 Coursework Assignment N/A
Exam - Autumn Semester 70 Advanced Materials 2

Syllabus content

Colloidal systems: This part of the module will focus on structure-activity relationships in colloidal systems relevant to important applications in industry and healthcare, plus advanced methods used for their characterisation. Topics will include advanced characterisation techniques, structure activity relationships in surfactants, polymer solutions, polymer particle interactions, polymer surfactant interactions and supporting case studies.  

 

Synthesis of heterogeneous catalysts: This part of the module will focus on the synthesis of catalysts and supports. It will include case studies of different catalyst systems. Different synthesis methods will be introduced such as sol-gel, hard and soft templating, antisolvent precipitation to prepare bulk catalysts and supports. Methods of preparing supported catalysts will also be covered including impregnation, deposition-precipitation, and the use of pre-formed sols.  

 

Design advanced materials: This part of the module will focus on the fundamental properties of advanced materials. It will include review of the properties of semiconductors, and the impact of defects on applications, including light-emitting diodes, transistors, and ionic transport; the properties of extended surfaces on geometric, energetic and electronic properties; the properties of mono- and bimetallic nanoparticles; and explaining nanoparticle-support interactions and how these, as well as environment, can modify the structural and electronic properties and change the functionality of an advanced material.  


CHT247: Modern Catalysis

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT247
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Jennifer Edwards
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module demonstrates fundamental concepts in catalysis and expands on these to demonstrate how modern catalysis addresses major chemical and environmental challenges. These challenges include: 

 

  • Environmental air and water protection (through control of VOC and CO air emissions and chemical/biological remediation of wastewater), 

  • Using catalysis to provide clean energy (through the development of sustainable non-fossil fuel sources, and processes underpinning clean hydrogen generation), 

  • Upgrading low-value and waste products to provide alternative, non-fossil pathways to commodity and fine chemicals, 

  • Alternative sustainable pathways for hydrogen peroxide synthesis, and integration of parallel oxidation processes to generate high oxidation products in a more sustainable way, 

  • Fine and bulk chemical synthesis of chemicals crucial for modern living, 

  • Replacing supply-limited precious metal catalysts by less rare materials, 

 

The basic principles of catalysts synthesis will be covered, and the importance of complementary catalyst characterisation methods (to identify the active site) will be highlighted. Information on the physical properties of the catalyst will be used to demonstrate catalysts mechanisms. The content will draw strongly on the complementary fields of nanoscience, solid-state chemistry, surface science, organometallic chemistry, and synthetic organic chemistry.  

On completion of the module a student should be able to

On successful completion of the module, you should be able to: 

 

  • Describe the fundamental principles of structure, function, and activity of heterogeneous and homogeneous catalysts in modern catalytic processes, 

  • Evaluate experimental data from catalysts performance experiments and relate this to physical and chemical information describing catalyst structure and then use this to propose a catalytic mechanism solution. 

  • Apply concepts of homogeneous catalysis to propose hypotheses and detailed reaction mechanisms for homogeneous modern catalytic reactions, 

  • Describe how ligand design enables better chemo-, regio- and stereo-control in homogeneous catalysis 

  • Propose original catalytic solutions to emerging real-world problems and suggest potential catalysts for unseen problems. 

How the module will be delivered

You will receive course content delivered primarily using face to face lectures. The course consists of 10 x 2-hour lectures during the Spring semester, with approximately 3 lectures a week for 3-4 weeks. Lectures may include some worked problems and informal formative questions to support principles introduced. These will help you to address the learning outcomes and provide opportunities to apply knowledge and develop understanding. 

The lecture schedule will follow the module map published prior to the start of the module. Lectures will be recorded and will be available following the live sessions. A combination of lecture slides and additional supporting notes will be available for you prior to the face-to-face lectures. 

Lecture material will be supported by two workshops. These are formative and will take the form of face-to-face sessions, and these will focus on supporting problem solving based on material from lectures. These formative workshops will provide you with guidance and support for the assessed coursework and examination A single summative coursework assessment will be released after the final lecture.

Skills that will be practised and developed

Skills developed through formal module learning outcomes and summative assessment include: 

 

Academic Skills: 

 

  • In the workshop you will take part in a group exercise where a solution is developed that applies theories taught in a lecture to a scaled, real-world problem. This exercise will allow you, as a team, to generate original ideas and apply and innovative solution based on the specific needs of the real-world solution. The teamwork aspect allows you to collaborate in a positive way and will develop your verbal communication skills. 

  • One option in the summative assessment involves a critical assessment of text generated by AI where the topic is related to one of the lectures. This builds on critical thinking and gives an opportunity to present your own interpretation of the text and communicate this is a succinct and effective manner. 

 

Chemistry-Specific Skills: 

 

  • You will develop chemistry specific skills, focussed on applying ideas from fundamental physical and inorganic chemistry to understand how these can be applied to provide solutions in modern catalysis applications. The topics covered relate to global issues such as Net Zero, water scarcity and renewable energy. Knowledge of these areas of chemistry will help develop your ethical, social, and environmental awareness. 

  • Developing these skills will allow you to start to select appropriate catalysts for specific target reactions with some awareness of stakeholder needs (individuals, organisation). You will develop skills in translational catalytic application by understanding the wider content that emerging modern chemical challenges present and developing and adapting established catalysis processes to address them. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Graduate Attributes – Assessment:    

  

Written Assessment                  30% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Exam                                         70% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 3. Ensure healthy lives and promote well-being for all at all ages

Goal 6. Ensure availability and sustainable management of water and sanitation for all  

Goal 7. Ensure access to affordable, reliable, sustainable, and modern energy for all  

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation

Goal 11. Make cities and human settlements inclusive, safe, resilient, and sustainable  

Goal 13. Take urgent action to combat climate change and its impacts 

 

How the module will be assessed

Summative assessment will take the form of a written examination and a written piece of coursework.

A two-hour closed book written exam will test your ability to demonstrate knowledge and understanding of the syllabus content, and your ability to apply the techniques and concepts covered to problems solving that are related to familiar and unseen examples. 

The summative coursework will allow you to demonstrate your ability to review and evaluate research from the literature through the preparation of a short-written report (2 pages). You will be able to choose between 2 questions relating to homogeneous or heterogeneous catalysis and will need to identify how original, peer reviewed research articles can be used to address the specific problem outlined. You will receive feedback on your coursework well before the written exam.

Your learning will also be supported by the formative workshops, and feedback provided either orally or in writing during and after the sessions. There will be a focus on supporting problem solving based on applying knowledge and understanding of modern catalyst approaches for unseen, emerging applications. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 30 Coursework N/A
Exam - Spring Semester 70 Modern Catalysis 2

Syllabus content

The syllabus will cover 3 main themes: 

 

(i)           Catalysts for environmental protection - This part of the module concentrates mainly on catalytic treatment of emissions from stationary sources. This will also focus on the removal of biological and chemical contaminants from water (in both industrial and domestic settings). This theme also focusses on clean energy, with green carbon sources discussed, and the hydrogen economy (and the catalytic processes that provide it) emphasised. There is further emphasis on the fundamental underlying aspects of the chemistry, in respect to catalyst preparation, microscopic, macroscopic, and surface structure, and probing the catalytic mechanism. 

 

(ii)        Homogeneous catalysis in the 21stcentury - This part of the module considers how established homogeneous catalytic systems can be improved in terms of both cost and environmental impact.  In particular, application of the principles of ‘green catalysis’ will be emphasised with regard to the nature of the catalyst, the chemical process itself and greener alternatives to established materials. 

 

(iii)        Grand challenges for catalysis –Fundamental catalyst studies can be translated to technology and process improvements, where lab scale discoveries are exploited on a commercial level, improving process efficiency using less toxic catalyst materials. Examples of novel and more sustainable production routes of fine and commodity chemicals will be explored. The processing of waste streams (with emphasis on non-fossil source) to value added chemicals will be illustrated. Integration of heterogeneous catalysis processes into chemical synthesis routes to provide less energy intensive chemical synthesis will be demonstrated. 

 

Essential Reading and Resource List 

 ‘Handbook of Green Chemistry – Green Catalysis’: Vol. 1 Homogeneous Catalysis; Vol. 2 Heterogeneous Catalysis, eds. P. Anastas and R.H. Crabtree, Wiley VCH, 2009 

“Grand challenges for catalysis in the Science and Technology Roadmap on Catalysis for Europe: moving ahead for a sustainable future” P. Lanzafame, S. Perathoner, G. Centi, S. Gross, E.J.M. Hensen, Catal. Sci. Technol., 2017, 75182-5194. 


CHT313: Molecular Modelling

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT313
External Subject Code 101050
Number of Credits 10
Level L7
Language of Delivery English
Module Leader DR Alberto Roldan Martinez
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module exposes students to the range of computational methods that can be applied to diverse chemical problems, from the structure and property of molecules to chemical thermodynamics, kinetics and reactivity. 

Methods for describing molecules, ranging from quantum chemical and molecular orbital methods for relatively small molecules to atomistic simulation of larger, more complex systems will be discussed.

Throughout, the ability to extract chemically relevant properties from molecular modelling experiments will be a major focus.  

On completion of the module a student should be able to

  • Explain the fundamentals of theories underpinning the range of modelling methods available to tackle chemical problems.    

  • Design appropriate feasible methodology for the modelling of a given chemical problem, drawing on knowledge of particular methods, errors and computational costs.   

  • Identify the key results obtained from calculations and interpret these with regard to the physics/chemistry of the problem.    

  • Critically evaluate computation schemes presented in primary chemical literature.   

  • Analyse and evaluate the errors in modelling schemes.   

 

How the module will be delivered

A blend of on-line learning activities with face-to-face learning support and feedback.   

20 x 1-hour lectures, 4 x 1 h tutorials. Lectures will deliver the core course content, addressing all learning outcomes. 

Formative tutorials will selectively address learning outcomes, with emphasis on problem solving and forging links between topics.  

The module does not contain a practical component, or instruction in the use of particular software elements, but instead develops understanding of the underlying theoretical concepts through discussion of examples of application to chemical problems.   

Skills that will be practised and developed

Academic Skills: 

 

You will analyse a published research paper, extracting the key scientific outcomes, research rationale, and techniques, helping you develop both critical thinking and written communication skills.  

 

Chemistry-Specific Skills:  

 

You will develop the necessary skills to identify the appropriate theoretical and computational methods to predict and interpret the properties of molecules, liquids, and surface processes, developing independent and critical thinking skills.  

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

In-Course Assignment              30% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

  •  

 

Exam                                         70% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

 

Resit Exam                               100% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

    

Sustainable Development Goals:      

   

This module does not align with any of the Sustainable Development Goals, but its topics do underpin all.    

How the module will be assessed

The module is assessed through two components: a 2-hour exam in the January exam period (70%), and a take-home assignment during the teaching period (30%).  

The take-home assignment gives opportunity for students to demonstrate understanding of concepts and methods presented, and their ability to analyse the rationale and outcomes of a piece of primary literature. Feedback is provided.  

The examination consists of a variety of questions which test a candidate’s knowledge and understanding of concepts, and their ability to deploy those concepts on unseen problems.  The portfolio of question parts is constructed so that some parts can be answered with a basic level of knowledge and understanding, and other parts support the demonstration of deeper understanding and capability.  The overall balance of these aspects is designed such that candidates can demonstrate satisfaction of the learning outcomes at a basic level and receive the pass mark.  

A number of elements of formative course work are provided in addition, in order to give the opportunity to deepen understanding through application, with feedback through a combination of interactive tutorials and written comments.   

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:   

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.  

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session. 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 30 In-course assignment N/A
Exam - Autumn Semester 70 Molecular Modelling 2

Syllabus content

Schrödinger equation, Born-Oppenheimer approximation, potential energy surface. Topography of potential energy surfaces. Parameterised forms for bonded interactions and non-bonded interactions. Application to varied chemical systems.  

Correlated wavefunction and density-functional methods; electromagnetic properties; excited states; intermolecular interactions.   

Fundamentals of Molecular Dynamics; time propagation algorithms; periodic boundary conditions; radial distribution functions; thermodynamics of ensembles; examples of applications.  

Hartree-Fock and Density-Functional theories for periodic solids; molecular and dissociative adsorption; reactivity and principles of microkinetic modelling.  

 


CHT317: Molecular Modelling for Postgraduate Chemists

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT317
External Subject Code 101050
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Stefano Leoni
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

The aim of this module is to present advanced concepts of physical and theoretical chemistry and to demonstrate how molecular modelling and simulation techniques are used in modern chemical and materials research. 

The focus will be on applications across the chemical sciences. Potential areas of application include systems with complex electronic structure, structure, and function of biopolymers such as proteins and nucleic acids, solid-state/surface/nanoparticle chemistry, heterogeneous catalysis and (bio)catalytic reaction mechanisms, and modern applications of machine learning and AI.  

 

On completion of the module a student should be able to

By the end of this module, you will be able to: 

 

  • Systematically understand key aspects, strengths, and weakness of different molecular simulation methods for different classes of chemical problem and act autonomously in planning and implementing simulations tasks in specific scenarios; 

  • Demonstrate self-direction and originality in planning simulations of chemical, bio-molecular and/or solid-state systems and comprehensively identify appropriate choices of methodology, parameter sets and data analysis approaches for chemical problems of interest; 

  • Creatively plan strategies for new simulations based on literature case studies by putting together strategies based on functional elements of hitherto disjoint approaches. 

  • Critically assess data results and give examples of findings and procedures from a variety of sources (literature, electronic databases and/or calculations) in a manner suitable for molecular modellers and non-specialists, by outlining core findings and relevant methodological choices and by criticising scope and impact of the main findings based on current field’s standards. 

  • Demonstrate critical awareness of current problems and scope of machine learning (ML) approaches into molecular modelling, by performing specific tasks of training and prediction based on neural networks ad by contrasting outcomes with non-ML-supported approaches. 

How the module will be delivered

A blend of learning activities with face-to-face small group learning support and feedback.

Key concepts will be explained by use of structured lectures focussing on specific topics, supplemented by textbook, web-based and/or primary literature reference material as appropriate. 

Students will be expected to study from this material in advance of timetabled classes. Face-to-face classes will build on material from lectures, and will be based around worked problems, live and/or literature simulations and informal ad hoc formative tests.

9 x 1-hour lectures, 3 x 1-hour tutorials and 3 x 2-hour workshops.  

 

Skills that will be practised and developed

 

Intellectual skills: 

 

  • Ability to translate formal theory into effective molecular modelling strategies, for molecules and solids. 

 

Chemistry-Specific Skills: 

 

  • Ability to apply ideas from physical chemistry and molecular modelling to understand how theoretical descriptions of molecules and solids can be used in conjunction with modern software packages; 

  • Ability to modify existing numerical approaches to solve new problems or adapt to new data; 

  • Use of numerical methods to simulate the behaviour of molecular structure, properties, and reactivity;  

  • Obtaining information of chemical reactivity in molecules and solids by understanding and applying methods of free energy calculations; 

  • Learn molecular properties by setting up suitable molecular descriptors, train, and test machine learning algorithms; 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

 

 Coursework                           30% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 

 Class Test                             70% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 

Sustainable Development Goals:      

   

This module does not align with any of the Sustainable Development Goals, but its topics do underpin all. 

 

How the module will be assessed

Several ad hoc formative assessments will be used to exemplify concepts introduced in lectures, with feedback orally during or shortly after the timetabled session. A typical formative assessment will contain a revision of key coursework concepts, as well as at least one unseen problem, whose creative solution will instigate self-direction and originality in approaching molecular simulations problems. At least one longer formative assessment will be set, based around analysis of literature or student-generated data. 

A written class test will assess the student’s ability to demonstrate knowledge and understanding of the syllabus content, and their ability to apply the techniques/concepts covered to unseen problems. Coursework will allow students to demonstrate ability to generate and/or analyse data obtained from simulations, and to critically review literature knowledge through the preparation of a written report. 

Marks will reflect the extent to which students have met the module learning outcomes shown above. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Class Test 70 Class Test N/A
Written Assessment 30 Coursework N/A

Syllabus content

The module will consist of several self-contained blocks that represent contemporary directions of research in computational chemistry. These topics will remain subject to variation as the field develops and will be expanded or realigned to current trends as appropriate. 

 

  • Bio-molecular modelling: prediction of peptide and protein structure; homology modelling; Ramachandran maps; protein folding models. Forcefields for bio molecules; all-atom, united-atom and coarse-grained models. Modelling enzyme function: QM/MM methods; sampling techniques. Modelling of nucleic acids: challenges for DNA and RNA; quantum mechanical and forcefield methods for nucleic acids. 

  • Solid-state modelling: Periodic quantum chemistry introduced using concepts from tight binding theory.  Use of plane wave basis sets and pseudopotentials in periodic systems. The structure of metal surfaces: the nature of surface states and their effect on the density-of-states and Fermi level; activation of molecules at surfaces; quantum-mechanical simulation of surface-catalysed reactions. 

  • Machine-learned interatomic potentials. Theoretical background and applications of ML techniques in molecular dynamics simulations. Data-driven approach to structure-property relationships. 


CHT327: Engineering Biosynthesis

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT327
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr James Redman
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

 

This module concerns the engineering of biosynthetic pathways for synthesis of organic chemicals for use as pharmaceuticals, agrochemicals, flavours/fragrances, and fuels.  

 

Biosynthesis enables sustainable manufacture of complex molecules in multistep routes using fermentation from renewable feedstocks under benign conditions.  

 

The combination of synthetic chemistry with biosynthesis provides an efficient avenue to novel compounds for screening as drugs.  

 

The strategies and challenges for production of organic chemicals through biosynthetic pathways will be described and illustrated with examples drawn from the biosynthesis of different classes of secondary metabolite. 

 

 

On completion of the module a student should be able to

 

  • Propose intermediates and reaction pathways for the biosynthesis of a given metabolite.  

  • Design and critically evaluate strategies to engineer enzymes and metabolic pathways to produce a compound of a given structure. 

  • Retrieve, interpret and communicate data, findings and procedures relating to biosynthesis from journals and databases. 

  

How the module will be delivered

 

The module will be delivered primarily using lectures (22 hours across one semester) where the principles of biosynthesis of different classes of secondary metabolite will be introduced including case studies of engineering from the literature.  

 

In addition, lectures will include worked problems and informal ad hoc formative activities.  

 

Workshops (two formative, one summative) will be used to enhance and assess problem-solving and literature searching skills. 

 

Skills that will be practised and developed

Chemistry-Specific Skills: 

 

  • Assignment of metabolites to a particular pathway, and proposal of biosynthetic intermediates and transformations;   

  • Apply strategies for modifying a biosynthetic pathway to increase yields or produce novel products;  

  • Predicting the outcome of biosynthetic processing of an unnatural substrate;   

  • Choosing appropriate synthetic substrates for biosynthetic pathways to generate novel compounds.  

  • You will practice applying the concepts of synthetic organic chemistry to enzyme catalysed biosynthetic pathways.  

  • You will develop skills in proposing appropriate starting materials and enzymes to synthesise a given target structure. 

  

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes: 

  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

 Coursework                                  100% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 3. Ensure healthy lives and promote well-being for all at all ages 

 

Goal 12. Ensure sustainable consumption and production patterns 

 

Goal 13. Take urgent action to combat climate change and its impacts 

 

Goal 15. Protect, restore, and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss 

 

How the module will be assessed

Formative assessment: The first two workshops will be assessed formatively, and feedback provided either orally or in written form. This will give you an opportunity to revise the factual module content and to practice applying it to deduce and propose biosynthetic pathways. 

 

Summative assessment: A summative assessed workshop in the form of a written report will allow the student to demonstrate his/her ability to use electronic resources to locate relevant information in the literature to provide the context for solution of a problem in biosynthetic engineering. You should evaluate the merits of alternative solutions and suggest contingency plans. 

 

A written exam (2 hour) will test the ability to explain biosynthetic pathways, propose pathways for production of previously unseen compounds, propose and interpret experiments in biosynthesis. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

The reassessment will be by an examination during the resit examination period. 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 30 Coursework N/A
Exam - Spring Semester 70 Engineering Biosynthesis 2

Syllabus content

 

Rationale for engineering pathways in primary and secondary metabolism for sustainable production of complex organic chemicals. 

 

Biosynthetic pathways for common classes of secondary metabolite, with examples drawn from polyketides, terpenoids, alkaloids and non-ribosomal peptides. 

 

Strategies for modifying enzyme selectivity and activity – rational design, screening, directed evolution approaches.  

 

Case studies of engineering metabolite biosynthesis. 

 

Reconstituting metabolic pathways in new hosts (choice of host - considerations such as precursor availability, toxicity of intermediates, compartmentalisation, PTMs of pathway enzymes, accessory proteins).  

   

Efficiently creating molecular diversity by combining synthetic chemistry with biosynthesis (mutasynthesis) and combinatorial biosynthesis. 

 


CHT330: Applications of Advanced Spectroscopic Methods

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT330
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader PROFESSOR Philip Davies
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

Spectroscopy is one of the central pillars of chemistry, providing essential information on the reactants, products and critically, intermediates, involved in every chemical reaction studied. 

In this module, we discuss applications of spectroscopy across a very broad range of fields with a particular emphasis on interfacial and atmospheric processes where Cardiff has particular expertise. 

The module describes some aspects of the cutting edge of research being undertaken in the School and discusses the unique tools being exploited at Cardiff to investigate these areas. 

 

On completion of the module a student should be able to

  • Describe a range of experimental methods for determining surface structural and spectroscopic information.  

  • Explain the basic concepts underpinning a range of surface sensitive techniques and use that knowledge to explain experimental data generated by the techniques.  

  • Describe the difference between electron microscopy techniques, including scanning electron microscopy and transmission electron microscopy. 

  • Critically evaluate why electron microscopy and aberration-correction is required for atomic-resolution imaging. 

  • Apply understanding of spectroscopic techniques in the electron microscope to determine composition and oxidation state of sample data. 

  • Describe Wood’s system of surface structure notation and demonstrate its application in new situations. 

  • Explain why there are problems inherent in obtaining information from surfaces under ambient conditions, and of the techniques being employed to address these problems. 

  • Interpret data acquired from a range of surface sensitive spectroscopies and microscopies 

How the module will be delivered

The module will be delivered in 10 two-hour lectures, supplemented by 3 one-hour formative class tutorials. 

Skills that will be practised and developed

 

Chemistry-Specific Skills: 

 

  • The skills practiced in this module that relate to the Cardiff graduate attributes, are indicated with “GA” and bold type. 

  • The module aims to create an awareness of the special problems of studying the nanoscale and the interface region and the tools that are available to address those problems. 

  • Students will be trained to identify the special circumstances of spectroscopy in these fields, to recognise the information that can be obtained and the best choice of tools to gather that data and finally in the methods that can be used to extract useful information from the data the different microscopies and spectroscopies produce. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Graduate Attributes – Assessment:    

  

Coursework                     30% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

 

Exam                               70%  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Resit Exam                     100% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:  

 

Goal 7. Ensure access to affordable, reliable, sustainable, and modern energy for all  

Goal 12. Ensure sustainable consumption and production patterns  

Goal 13. Take urgent action to combat climate change and its impacts

Goal 14. Conserve and sustainably use the oceans, seas, and marine resources for sustainable development  

How the module will be assessed

Summative assessment will consist of two parts: 

 

  • One two-hour exam consisting of four compulsory questions reflecting the three elements of the course. 

  • One piece of written coursework which will take approximately 2 hours to complete and will consist of a set of questions from across the module syllabus.  

 

Formative Assessment 

 

  • For each of the three segments of the course, a worksheet of questions will be issued and discussed at a scheduled “tutorial” allowing students the chance to assess their competence. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 30 Workshop N/A
Exam - Spring Semester 70 Applications of Advanced Spectroscopic Methods  2

Syllabus content

Fundamental principles of interface spectroscopy and microscopy 

  • Fundamental limitations of spectroscopy at interfaces and methods of addressing them 

  • Advanced experimental methods for exploring interface science 

  • Surface structures and conventions for describing them 

  • Experimental methods for exploring surface structure 

  • Use of scanning electron microscopy and transmission electron microscopy for understanding material structure. 

  • EELS and EDXS for determining composition and oxidation state. 

  • Factors influencing resolution of electron microscopy. 

  • The unique advantages and applications of synchrotron light sources for probing interface environments 

  • XPS, XAFS and real-time “operando” measurements applied to metallic and oxide catalytic surfaces in situ 


CHT333: Supramolecular Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT333
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Louis Luk
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

Supramolecular chemistry, which explores the concept of intermolecular dynamic interactions, plays a pivotal role in advancing organic chemistry, chemical biology, materials science, nanotechnology, and other areas where applied science is crucial. This module introduces students to the shift from classical molecular approaches, emphasising the understanding of concepts based on non-covalent bonding interactions among molecules and ions across various states and interfaces. 

This course will cover the fundamental principles of supramolecular chemistry, covering molecular cages, surface self-assembled networks and metal-organic frameworks. We will also explore their applications in chemical sensing and energy storage, highlighting the social and environmental implications of these supramolecular innovations in every life. Additionally, we will examine the supramolecular interactions involving nucleic acids and proteins, discussing their applications in drug delivery, biotherapeutic design, and chemical manufacturing. This exploration will further enhance students' understanding of the social and ethical aspects inherent in these scientific advances.

Beyond foundational knowledge, the course emphasises the development of independent thinking, creativity, and effective communication skills through collaborative projects. Students will be tasked with designing novel supramolecular systems of fundamental and/or applied interest, practicing their communication skills through group presentations. This approach not only reinforces their understanding but also nurtures creativity, encouraging them to design innovative molecular organizations with both fundamental and applied significance. 

On completion of the module a student should be able to

  • Identifying the critical role of supramolecular chemistry in applied science fields such as organic chemistry, chemical biology, materials science, and nanotechnology. 

  • Learn to describe the analytical methods used to study molecular interactions, a skill essential to a broad range of career paths. 

  • Discuss the application of supramolecular chemistry in industries and medicine, which will boost students' ethical and social awareness. 

  • Utilise fundamental concepts of supramolecular chemistry to develop logical solutions to novel problems, promoting innovative and reflective thinking. 

  • Retrieve, interpret and communicate data, findings and procedures relating to supramolecular chemistry from journals and databases. 

How the module will be delivered

The module will be delivered primarily using lectures (22 hours) where the principles of supramolecular chemistry will be introduced including case studies from the literature. In addition, lectures will include worked problems and informal ad hoc formative activities. 

Workshops (one formative, one summative) will be used to enhance and assess problem-solving and literature-searching skills. 

Skills that will be practised and developed

Chemistry-Specific Skills: 

 

  • Students in this course will develop employable attributes applicable to a broad spectrum of career paths. 

  • They will gain a deep understanding of supramolecular chemistry and be familiarised with crucial data analysis skills essential in diverse job prospects.  

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:  

   

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

Oral Presentation                    30% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 

Exam                                       70% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Resit Exam                            100% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:  

 

Goal 6. Ensure availability and sustainable management of water and sanitation for all  

Goal 7. Ensure access to affordable, reliable, sustainable and modern energy for all  

Goal 14. Conserve and sustainably use the oceans, seas and marine resources for sustainable development

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development 

How the module will be assessed

Formative assessment: The first two workshops will be assessed formatively, and feedback provided either orally or in written form. This will give students an opportunity to revise the module content and to apply it to deduce and propose solution for supramolecular chemistry-based questions.

Summative assessment: A summatively assessed workshop in the form of an oral presentation will allow the student to demonstrate their ability to use electronic resources to locate relevant information in the literature to provide a plausible proposal for a contemporary research topic.

A written exam (2 hours) will test the ability to predict intermolecular interactions as well as propose and interpret experiments in supramolecular chemistry. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment are only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.

The reassessment will be by an examination during the resit examination period. 

Assessment Breakdown

Type % Title Duration(hrs)
Presentation 30 Oral Presentation N/A
Exam - Spring Semester 70 Supramolecular Chemistry 2

Syllabus content

  • Basic concepts in self-assembly and self-organization, including a systems chemistry approach, thermodynamics, and kinetics of host-guest processes along with the main characterization techniques.  

  • Complexation of neutral molecules in aqueous solution and their technological applications - sensors and drug delivery; Template effects & molecular self-assembly approach towards nanostructures in solutions (including molecular cages and inorganic nanotubes), on surfaces (2D networks and topology considerations);  

  • Non-covalent interactions involving aromatic rings; hydrogen-, halogen- and chalcogen-bonding interactions.  

  • Dynamic covalent bonds & supramolecular polymers.  

  • Experimental techniques and methods used to understand both nanoscale and ultrafast chemistry critical to many supramolecular processes and materials;  

  • Molecular machines, from catenanes and rotaxanes to more complex multi-station multi-stimuli responsive supramolecular systems.  

  • Basic concepts of molecular recognition in biology, including cell architecture, biomolecular interactions, structure of essential building units, lipids, DNA/RNA, protein, sugar; natural Ion channels, including peptide-based ion change, cation/anion complexation, cross-membrane ion channel.  

  • Supramolecular chemistry in biotechnological applications (e.g. designer enzyme, antibody drug conjugate, DNA-templated synthesis)  


CHT342: Catalytic Materials for Green Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT342
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Professor David Willock
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module will cover the synthesis, characterisation and simulation of the catalytic materials that find applications in the Green Chemistry and energy sectors. 

The current trend in chemistry to reduce our dependence on fossil sources of carbon for chemicals and fuels is giving rise to a whole new set of challenges in catalysis. This module will discuss the environmental drivers for this shift. 

We will introduce the mechanistic pathways used to transform renewable resources into useful chemicals and identify the characteristics of the catalysts required. We will also survey the synthesis of catalysts and the applications for these materials. 

The module will emphasize how careful characterisation and simulation approaches can give a structure/activity level of understanding in heterogeneous catalysis that helps to design and optimise catalytic materials. 

You will develop critical analysis skills through study of literature case studies and quantitative approaches to defining how environmentally friendly a chemical process really is. 

On completion of the module a student should be able to

  • Discuss the environmental impact of chemistry and the use of catalysis to mitigate this impact. 

  • Appreciate the range of methodologies used in synthesising heterogeneous catalytic material including pre- and post-treatments applied to enhance/control catalytic activity.  

  • Describe the control of surface features, material phases and compositions that can be achieved using a variety of synthetic approaches.  

  • Interpret data from the characterisation methods used for heterogeneous catalytic materials and discuss the information which each method provides and reflect on the overall picture obtained by combining data from different approaches.  

  • Critically assess the mechanisms of sample catalytic target reactions in the Green Chemistry and energy sectors.  

  • Work with kinetic rate equations to interpret catalytic data giving conversion and selectivity as a function of time.  

  • Describe in situ measurements that are used to scope out elementary surface reactions during catalysis.  

  • Identify the main computational chemistry approaches used in the simulation of catalytic materials and catalysed reactions.  

  • Appreciate the use of computer simulation in establishing the electronic and geometric features of active sites on catalyst surfaces.  

  • Demonstrate how computer simulation is applied to map out reaction energetics for key steps in heterogeneously catalysed reactions. 

  • Analyse example experimental and computational data from the literature on mechanisms of interest for Green Chemistry.  

  • Relate computational and experimental information on catalytic systems to explain the relationship between structure and performance.  

How the module will be delivered

The module content will be delivered via face-to-face activities lectures and discussion workshops. Lecture material will be recorded and provided to support your independent learning. The material will also be supported by formative self- assessment tests introduced at regular points in the delivery schedule. 

The module will consist of 24 hours of lecture and 4 hours of discussion workshops and worked example problems. 

The week-by-week delivery schedule and timing of summative and formative tasks will be described in the module map.  

Skills that will be practised and developed

Academic Skills: 

 

  • You will also have opportunities to apply these skills to analyse examples drawn from the scientific literature and be encouraged to collaborate with your peers in reviewing case studies.  

  • The formative and summative assessments will allow for collaborative working when researching literature data enabling discussion of ideas between peers.  

  • These discussions will focus on the scientific reasoning required to develop a process but will also be broader taking into account commercial aspects.   

 

Chemistry-Specific Skills: 

 

  • You will have the opportunity to develop your independent critical analysis and problem-solving skills, dealing with data from a variety of methods to come to a rounded understanding of catalyst structure, materials properties, and mode of operation in key catalytic processes.  

  • The module is centred in sustainable chemistry, and you will also acquire the vocabulary and analytical skills to exercise critical judgement regarding the contribution a particular catalytic process can make to improving the environment and reducing the impact of anthropogenic activity. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

 Written Assessment                     30% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Exam                                             70%  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Resit Exam                                   100% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

Goal 7. Ensure access to affordable, reliable, sustainable, and modern energy for all  

Goal 12. Ensure sustainable consumption and production patterns  

Goal 13. Take urgent action to combat climate change and its impacts  

Goal 14. Conserve and sustainably use the oceans, seas, and marine resources for sustainable development  

Goal 15. Protect, restore, and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss 

How the module will be assessed

Formative assessments: A formative assignment will be used to give experience of drawing data from literature sources and use ideas from the module to interpret that data in terms of sustainability. Full engagement with the self-assessment exercise will prepare students for the summative assessment components of the module.  

 

Summative assessment will consist of a single piece of written work combining a number of literature sources. The marking scheme will assess the student’s understanding of the material in the literature sources and their ability to critically assess the way that a proposed process conforms to the concepts of Green Chemistry. There will also be an examination at the end of the semester in which the module is delivered.

The assignment style work will be set with at least a 2-week deadline to ensure that you can follow up the required literature study at your own pace. The examination time will include allowance for those with special provisions.  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period.

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 30 Essay on catalytic materials for Green Chemistry N/A
Exam - Autumn Semester 70 Catalytic Materials for Green Chemistry 2

Syllabus content

The module will cover the synthesis of catalytic materials for Green Chemistry and energy sectors. The principals of Green Chemistry will be reviewed with current literature examples of industrial processes that have been superseded by more sustainable chemistry.  

 

The common metrics of atom economy and E-factor will be discussed in detail and students given the opportunity to evaluate these factors for example processes. The characterisation methods used to measure properties such as the solid phases present, the effective surface area of catalysts and spectroscopic inspection of working catalysts will be addressed. 

The main approaches to the computer simulation of catalytic materials will also be introduced, with examples that integrate with the theme of Green Chemistry drawn from the literature. Reaction schemes will be presented and discussed based on calculated potential energy surfaces and the insights these given into the catalytic processes they represent. 

The overall aim of the module is to demonstrate how materials characterisation and simulation can help to inform a mechanistic understanding of heterogeneous catalysis for key reactions in Green Chemistry.   


CHT351: Drug Discovery Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT351
External Subject Code 100420
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Professor Thomas Wirth
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module aims to give students an overview of the methods used by medicinal chemists for synthesis of molecules in drug discovery programmes. 

Common reactions used in drug discovery for preparation of molecules for structure activity relationship (SAR) studies will be presented. 

Technologies used to support high-throughput and parallel organic synthesis and purification will be described. Design of experiments, hit/lead identification and reaction screening will be introduced.

Students will have the opportunity to propose strategies for efficient synthesis of novel molecules with a desired biological activity. 

 

On completion of the module a student should be able to

  • Describe catalysts and reaction mechanisms for commonly used transformations in medicinal organic chemistry.   

  • Devise strategies for efficient preparation of series of related compounds for structure-activity relationship studies.   

  • Devise laboratory scale synthetic routes to novel biologically active organic molecules.   

  • Critically comment upon the challenges encountered medicinal chemistry to generate hit and lead compounds for further development.   

  • Apply reactions of carbon atom functionalisation (Pd-catalysis, oxidation, reduction) in drug discovery.   

  • Apply reactions of nitrogen atom functionalisation (amide formation, multicomponent reaction, heterocycle formation) in drug discovery.  

 

How the module will be delivered

The module will consist of 12 1-hour lectures that will introduce the topics laid out in the syllabus.

Students will be expected to supplement these lectures with independent research of texts, specialist reviews and peer-reviewed literature and to discuss their findings in 2 × 1-hour formative tutorials. 

There will be workshops where students will be introduced to synthetic chemistry problems in a drug discovery context, followed by written submission of coursework. 

Skills that will be practised and developed

Academic skills:  

 

  • Ability to search and consult the literature and databases and provide synthetic meaningful solutions.  

  • Assess and solve problems in drug discovery together with their theoretical background and any strengths or weaknesses associated with them.   

  • Identification of chemical problems related to drug discovery. Several of the reactions used in drug synthesis are taking environmental and sustainability issues into consideration, the student can therefore demonstrate their skills in and awareness of these matters.  

 

Chemistry-Specific Skills: 

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

  

Graduate Attributes – Assessment:    

  

 Written Assessment              30% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 Exam                                     70% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 3. Ensure healthy lives and promote well-being for all at all ages 

Goal 12. Ensure sustainable consumption and production patterns  

How the module will be assessed

Written Exam, Workshop  

The workshop and the written exam will focus on different topics due to the timing of these events. They will enable the students to demonstrate that they have achieved the learning outcomes.  

Marking criteria will involve the validity of the provided answers to set questions and the ability of the student to handle unknown material connected to the course content allowing the student to demonstrate their ability to independently investigate problems and offer effective solutions. 

Further details (dates) are found in the assessment map.  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:   

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session.  

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 30 Workshop N/A
Exam - Autumn Semester 70 Drug Discovery Chemistry 2

Syllabus content

  • Sources of compounds for drug discovery: natural products, compound collections, existing drugs.  

  • Reactions for drug discovery chemistry: palladium catalysed cross couplings, acylation, allylations, sulphonamide formation, SNAr, reductive amination and multicomponent reactions; hydrogenation, amide formation; heterocyclic compounds synthesis, reactivity, and properties.   

  • Introduction to structure activity relationships.   

  • Drug discovery process.  


CHT352: Techniques in Drug Discovery

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT352
External Subject Code 100420
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr David Miller
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

In drug discovery it is essential we have ways of screening and refining compounds from initial lead or ‘hit’ compounds identified as promising compounds that may become drugs to treat a disease condition towards refining that compound into the final marketable drug molecule. 

 

This module concerns the techniques used for discovering ‘hit’ compounds, taking this forward to leads, and compound optimisation. You will encounter both experimental and in silico (computational) techniques. Methods of quantifying physico-chemical properties of compounds will be explored and related to compounds’ activity.  

 

Receptor binding assays and modelling of drug-receptor interactions will be presented. The module will introduce the student to a variety of key concepts in medicinal chemistry for predicting, measuring, and optimising the biological activities of novel compounds. 

 

On completion of the module a student should be able to

  • Demonstrate a comprehensive understanding of the physical basis of drug-receptor interactions and apply this knowledge to explain how drugs exhibit agonistic and antagonistic effects.  

  • To propose, evaluate and critique experimental assays for determination of drug mode of action including quantitative and qualitative information that may be obtained.  

  • Display a systematic understanding of the parameters used to describe the physico-chemical properties of compounds.  

  • Use structure activity relationships in concert with physico-chemical properties to predict activities of novel/unseen compounds and apply this to propose new drug molecule designs.  

  • Critically evaluate compound structures for drug-like and lead-like properties using industry standard rules.  

  • Display a comprehensive understanding and critical evaluation of the fundamental techniques for computational drug discovery.  

 

How the module will be delivered

 

The module will be delivered in the Autumn Semester and will comprise a blend of on-line learning activities with face-to-face small group learning support and feedback.  

 

The module will consist of a 12 × 1-hour lectures that will introduce the topics laid out in the syllabus. 

 

You will be expected to supplement these lectures with independent research of texts, specialist reviews and peer-reviewed literature and to discuss their findings in 2 × 1-hour formative tutorials.  

 

Computational chemistry material will be delivered in a 3-hour workshop including a working demonstration of a computational problem. There will be 2x formative workshops where you will be introduced to unseen problems in small molecule drug discovery, followed by an assessed workshop which will be a group oral presentation activity. 

 

Skills that will be practised and developed

 

Academic Skills: 

 

  • You will gain experience in project planning and problem-solving in the field of drug discovery. 

  • In a group activity you will collaborate on a challenging problem, critically evaluate material from the scientific literature and present your conclusions to you peers and lecturers in an oral presentation, developing both critical thinking and visual and verbal communication skills. 

  • Search and consult the literature and databases, to extract relevant information, to synthesise and critically evaluate their findings, and to apply this new understanding to solve previously unseen problems under time pressure 

  • Develop communication skills in written and oral form, and to make use of information technology for retrieving, manipulating, and presenting numerical and chemical information.  

 

Chemistry-Specific Skills: 

 

  • You will develop the necessary skills to identify the appropriate experimental techniques to measure the affinity and mode of action of drug molecules with their macromolecular targets, developing independent and critical thinking skills

  • You will be trained in using software packages in the field of medicinal chemistry molecular modelling, developing your analytical skills and ability to exercise critical judgement in evaluating sources of information. 

  • You will develop the necessary skills to assess experimentally derived data to evaluate pharmacological parameters of chemical compounds and exercise critical judgement in evaluating their likely efficacy as drugs. 

 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

 Group Presentation                  30% 

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future 

 Exam                                        70% 

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future 

 

 Resit Exam                               70% 

 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 3. Ensure healthy lives and promote well-being for all at all ages  

 

How the module will be assessed

The module will be assessed by a written examination that will tests the student’s knowledge gained from the lecture course and the ability to solve problems by integrating this knowledge with previously unseen information. Workshop coursework will assess the ability to integrate the material discussed in lectures with information retrieved from the literature to propose solutions to open ended problems. You will be expected to demonstrate their competence in the learning outcomes through submission of written coursework and transferrable skills such as teamwork and oral presentations in the assessed workshop.  

 

Formative workshops will be presented, and you will be expected to complete these 1 week after submission. Feedback will be returned and allow you to assess their progress against the learning outcomes and assessment criteria.  

The examination will sample all the module learning outcomes. 

 

A summative assessed workshop in the form of an oral presentation will allow the student to demonstrate their ability to disseminate a current drug discovery technique for solution of a problem in medicine in language that can be understood by an educated lay person.  

Any academic or competence standards which may limit the availability of adjustments or alternative assessments for disabled students should be clearly stated in line with guidance provided in the Reasonable Adjustment Policy and Procedure  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

The resit will consist of a 2-hour examination that will be weighted to 100% of the module mark and sample all of the module learning outcomes. 

Or.  

If the student has failed, the assessed workshop component the student will be given the opportunity to resit that portion of the module (100% of module mark) 

 

Assessment Breakdown

Type % Title Duration(hrs)
Presentation 30 Group Presentation N/A
Exam - Autumn Semester 70 Techniques in Drug Discovery 2

Syllabus content

 

All content is mandatory 

 

  • Concepts of receptors, agonists antagonists, partial and inverse agonists. Classification of agonists/antagonists and enzyme inhibitors;  

  • Pharmacodynamics. Quantitative models for receptor binding and antagonism;  

  • Functional and receptor binding assays (e.g. scintillation proximity assay, SPR, reporter assays);  

  • Ion channel assays (fluorescence, electrophysiology);  

  • Descriptors of physico-chemical properties of compounds, pKa, logP, logD, polar surface area etc.  

  • Structure activity relationships and QSAR;  

  • Pharmacophores and (bio)isosteres;  

  • Lipinski rules, rule of 3, ligand efficiency;  

  • Molecular modelling in drug discovery - homology modelling, virtual screening, docking;  

  • Fragment based drug discovery.  


CHT353: Drug Targets

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT353
External Subject Code 100423
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Fabrizio Pertusati
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

  • Drug discovery is an interdisciplinary subject that brings together chemistry, biochemistry, biophysics, cell biology, microbiology, and virology. This module presents an overview of protein and nucleic acid targets that have been exploited in developing existing drugs to treat a wide variety of diseases, such as bacterial and viral infections, cancers, and other disorders, including depression, chronic pain, and obesity.  

 

  • In order to compensate for the wide variety of student backgrounds, the course begins with online materials that review basic concepts needed to understand the role of cellular targets in disease and methods for determining the molecular mechanisms of drug action. Topics include, but are not limited to, protein and nucleic acid structure and function, enzyme kinetics and catalytic mechanisms, prokaryotic and eukaryotic cell structure, and protein/ligand interactions. 

 

  • The remaining modules will be taught using a blend of in-person and online methods.  

 

  • First, you will be shown the cell structure of bacteria together with key metabolic pathways that are targets for antibiotic discovery. Molecular details will be emphasised, and, when possible, the structural basis for drug/target interactions.  

 

  • In the second topic, you will be introduced to the life cycles of the viruses that cause human diseases, and the strategies used to kill the virus and minimise side effects. Next, the cell cycle will be discussed, together with the mechanisms that regulate cell division, as a prelude to understanding how different kinds of anti-cancer drugs exert their effects.  

 

  • Finally, you will be given a brief overview of G protein-coupled receptor-initiated signalling together with the strengths and weaknesses of using these receptors as drug targets for the treatment of pain and other diseases, such as depression. 

 

  • You will also have an assessed opportunity for independent study by writing, and presenting, a short report on commonly used drugs and/or emerging drug targets. 

On completion of the module a student should be able to

 

  

  • Define the functional roles of key organelles in eukaryotic cells; 

  • Identify the structural elements of proteins; 

  • Explain the molecular interactions involved in ligand binding and specificity; 

  • Be able to identify drug targets with therapeutic value; 

  • Explain how commonly used antibiotics/drugs kill bacteria, viruses or cancer cell 

  • Be able to solve quantitative problems related to drug binding and communicate findings using written reports and oral presentations 

 

How the module will be delivered

 

The module will be delivered in 6 x 2-hour face to face lectures, together with 2 x 1-hour tutorials that will discuss assigned reading from the primary literature.  

 

You will be able to obtain learning support and feedback by appointment with staff teaching the module, and from on-line materials such as lecture slides and videos, answer keys, practice tests, and optional reading.  

 

Review material will be delivered by pre-prepared videos, problem sheets, and reading assignments. As members of a project team, you will carry out independent study on a commonly used drug and its biological target, prepare an independently written report, and participate in a lecture presentation. Written feedback will be provided for all course activities. 

 

Two module tutors will each deliver half of the material and assignments, with the final examination featuring two questions prepared by each tutor.  

 

A formative workshop that provides learning support for examination-based assessment will be prepared by one tutor while the other oversees the summative exercise to develop independent study and communication skills. 

 

Skills that will be practised and developed

Academic Skills: 

 

  • You will learn to apply creative, imaginative, and innovative thinking to solve problems in basic and applied science; 

  • You will investigate problems and offer effective solutions, reflecting on and learning from successes and failures; 

  • You will learn to Identify, define, and analyse complex issues and ideas, and exercise critical judgement in evaluating sources of information; 

  • You will develop your intellectual curiosity and learn the principles of generating new knowledge 

 

Chemistry-Specific Skills: 

 

  • You will gain a molecular understanding of how drug/target interactions lead to clinical treatments for a wide variety of human diseases 

  • You will identify the economic and commercial reasons for the selection of drug targets; 

  • You will develop skills required to identify targets for the development of drugs against new diseases. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

 Presentation                   5% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 Written Report                25% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 Exam                              70% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

 

 Resit Exam                     70% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 3. Ensure healthy lives and promote well-being for all at all ages 

How the module will be assessed

 

A written exam (70%) will test knowledge and understanding of the course material, as elaborated under the learning outcomes. A formative, problem-based assessment will provide practice for the written examination and allow you to develop their abilities in solving quantitative and conceptual problems. An assessed project on the target and mechanism of action of a widely used drug will provide practice in obtaining and critically reviewing information from the scientific literature. Communication skills will be assessed by a written project report (25%) and a short oral presentation (5%) on this topic.  

Any academic or competence standards which may limit the availability of adjustments or alternative assessments for disabled students should be clearly stated in line with guidance provided in the Reasonable Adjustment Policy and Procedure  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Re-assessment is only permitted provided you have not failed more credits than allowed by the resit rules adopted by CHEMY. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by CHEMY. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

Reassessment will be based entirely on performance in the written examination. The reassessment will be in an identical format to the original assessment, enabling you to demonstrate your understanding of all learning outcomes. 

 

Assessment Breakdown

Type % Title Duration(hrs)
Report 25 Written Report N/A
Presentation 5 Short Presentation N/A
Exam - Autumn Semester 70 Drug Targets 2

Syllabus content

All content is mandatory 

 

Cells: prokaryotic and eukaryotic cell structure; 

Enzymes: protein structure; simple kinetic analysis; molecular basis of catalysis; inhibition; 

Ligand/receptor interactions: intermolecular interactions; role of water in ligand binding and specificity; quantitative description of ligand binding; 

Drug targets: nature of known drug targets; methods to validate proteins and nucleic acids as drug targets; emerging targets; 

Cell Wall Biosynthesis: enzymology of cell wall assembly; penicillins; vancomycin; 

Protein Synthesis: structure of ribosomes; chemistry of gene translation; macrolides; 

Nucleic Acid Metabolism: sulphonamides; fluoroquinolones; 

Drug Resistance: beta-lactamase; membrane transporters;  

DNA viruses: herpes simplex; inhibiting DNA replication; prodrugs; 

RNA viruses: influenza virus; haemagglutinin; neuraminidase; 

Retroviruses: human immunodeficiency virus; reverse transcriptase; HIV protease; 

Cell Cycle: regulation of cell division; signalling pathways; cytoskeleton; 

Nucleic Acid Metabolism: DNA replication terminators; cross-linking and intercalating agents; 

Cytoskeleton: tubulin polymerisation inhibitors; 

Receptor signalling: receptor tyrosine kinases; protein kinases; Ras and related GTPases; G protein-coupled receptors; agonists and antagonists 


CHT354: Drug Development from Laboratory to Clinic

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT354
External Subject Code 100423
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr James Redman
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module concerns the process by which drug leads are progressed through to clinical trials, regulatory approval, and marketing.  

 

The module will introduce students to the mechanisms by which drugs are delivered to their site of action and their fates in the human body. The process of testing of drug candidates in vitro and in vivo in animals and humans will be described.  

 

The issues surrounding production of larger quantities of drug in sufficient quality for clinical work will be introduced. Students will also gain an appreciation of the environmental, commercial, and regulatory aspects of drug development. 

On completion of the module a student should be able to

  • Propose and interpret assays for drug lead optimisation, candidate selection and progression. 

  • Identify biological, commercial, environmental, and regulatory issues in the development and manufacture of a drug and propose solutions. 

  • Retrieve, critically evaluate, synthesise, and communicate information from the drug development and manufacturing literature. 

How the module will be delivered

The module will consist of 6 × 2-hour lectures that will introduce the topics laid out in the syllabus. Students will be expected to supplement these lectures with independent research of texts, specialist reviews and peer-reviewed literature.  

 

There will be a workshop where students will consult the drug development literature and perform a problem-solving activity. 

Skills that will be practised and developed

Chemistry-Specific Skills: 

 

  • Develop skills in relating the molecular structure of drug candidates to biological and physical properties.  

  • Develop an understanding of the basis of the common assays, and their results, that are used in the pharmaceutical industry to select drug candidates for progression and subsequent formulation.  

  • Develop skills in critiquing and adapting small scale synthetic routes to larger scale drug production while considering safety, environmental and regulatory implications. Students will learn to extract relevant information from the literature, interpret data and make proposals to overcome challenges in drug development and manufacture.  

  • Generate, interpret, and present quantitative data and to solve previously unseen problems under time pressure. Students will have the opportunity to develop their communication skills in written form while making use of information technology for retrieving, manipulating, and presenting numerical and chemical information. 

 

Employability skills:     

This module is delivered and aligns with the following University Graduate Attributes:     

Consider own personal and professional ethical, social, and environmental responsibilities.   

Be mindful of the Climate Emergency and the UN's Sustainable Development Goals   

Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.   

Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.   

Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.   

 

Sustainable Development Goals:      

This module is delivered and aligns in working towards the following Sustainable Development Goals:    

Goal 3. Ensure healthy lives and promote well-being for all at all ages  

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation   

Goal 10. Reduce inequality within and among countries  

Goal 12. Ensure sustainable consumption and production patterns   

How the module will be assessed

Summative assessment: A single summative assessed workshop will involve selecting, consulting, and critiquing of the literature, identifying problems in drug development, proposing solutions and reporting in written form. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

Resit assessments will be in the same format as the original assessment. 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 30 Problem-based Workshop N/A
Exam - Spring Semester 70 Drug Development from Laboratory to Clinic 2

Syllabus content

  • Stakeholders in drug development;  

  • Introduction to pharmacokinetics, ADMET;  

  • Drug delivery and dosing;  

  • Metabolism, phase I and phase II, prodrugs;  

  • Toxicity, adverse drug reactions - mechanism based, idiosyncratic and reactive metabolites;  

  • Assays (for example - profiling, solubility, logD, permeability, HERG, P450 induction/inhibition, genotoxicity, stability);  

  • Introduction to process chemistry - route design, reaction scale up, purification.  

  • Quality assurance, environment, sustainability, and safety in drug manufacture.  

  • Introduction to clinical trials and regulation. 

 


CHT355: Trends in Drug Discovery

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT355
External Subject Code 100420
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Michaela Serpi
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module aims to give you a perspective on the current state of drug discovery and how this fit within the bigger picture of healthcare and economics.  

 

Trends in disease areas, targets, clinical trials, and new technologies for developing small molecule and biologics will be reviewed.  

 

You will be introduced to the challenges facing the pharmaceutical industry in terms of productivity, intellectual property protection, profits, and regulation.  

 

Business models for novel drug development novel may be scrutinised.  

 

The module will also consider the relationships between different stakeholders including patients, governments, charities, and industry.  

 

The module will also include exercises designed to develop critical analysis, oral and written communication, and to enhance your employability.  

 

The student will develop attributes as: effective communicator by listening to and taking in account the view of others and contribute to discussions; independent and critical thinkers by identifying, defining, and analysing complex issues and ideas and exercising critical judgment in evaluating source of information. 

 

 

On completion of the module a student should be able to

 

 

  • Describe how new technologies are being employed to increase productivity in drug discovery. 

  • Describe and explain trends in drug approvals and drugs currently in the pipeline. 

  • Discuss the activities performed during pre-clinical and clinical phases in drug development. 

  • Explain how drug discovery is influenced by financial and regulatory pressures. 

  • Discuss the roles of stakeholders in drug discovery, and the relationships between them. 

  • Describe and critically evaluate strategies to bring drugs to market faster and at lower cost. 

How the module will be delivered

 

The module will consist of 6 × 1/2-hour lectures from different speakers involved in various aspects of drug discovery in industry and academia.  

 

You will have the opportunity to meet with the speakers to discuss your presentation and line of work. 

 

You will be expected to supplement these lectures with self-directed research of texts, web resources, specialist reviews and peer-reviewed literature.  

 

You will be provided with guidance by a module tutor at one scheduled meeting (1 x 1 hour). 

 

Skills that will be practised and developed

 

Intellectual skills: 

 

  • You will need to gather, evaluate, and synthesise facts and opinions from multiple sources including lectures, in-person discussions, specialist periodicals and books.  

  • You will be able to draw conclusions about reaction mechanisms by combining experimental and spectroscopic data, developing analytical and critical thinking skills 

  • You will develop your ability to summarise and critically review potentially contradictory or incomplete information and opinions 

  • You will practice presenting complex ideas and arguments in written and oral form to a professional standard with the use of appropriate IT. 

 

Chemistry-Specific Skills: 

 

Student will - 

 

  • Learn about the design and development of a drug for different therapeutic indications. 

  • Identify the intellectual property process behind the development of drugs; 

  • The importance of patient advocacy role in rare disease; 

  • Learn about the design of clinical trials; 

  • Learn about the use of computer drug design in drug discovery; 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

  

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

 

  

Graduate Attributes – Assessment:    

  

Oral Presentation             100% 

  • Contribute to discussions, negotiate, and present with impact.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future. 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 12. Ensure sustainable consumption and production patterns  

How the module will be assessed

You will be assessed for a written assay on a chosen topic related to critical reviews/themes of current drug discovery and will be assessed for your quality and clarity of writing, coverage of the material in the literature, critical discussion, use of references and for the structure and presentation of the essay. You will be also required to give a short oral presentation on the same topic, and you will be assessed for your choice of content, clarity, logical structure, performance, and ability to answer questions.  

 

The exact topics of the essay and presentation will be chosen by you with the guidance of the course coordinator or of a module tutor but you will be expected to address different aspects of drug discovery, including technology and commerce. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Presentation 100 Oral Presentation N/A

Syllabus content

 

Mandatory content: 

 

  • Current trends and challenges in drug discovery; 

  • Emerging themes and technologies; 

  • Intellectual property, profit, and regulation 

 

Optional content: 

  • You will be required to develop greater knowledge and understanding of selected areas. The following is a representative, but non-exhaustive list of possible topics.  

  • Technologies/discoveries/emerging areas 

  • Fragment screening methods; 

  • Biological and macromolecular drugs – stem cell therapies, proteins (monoclonal antibodies), nucleic acids and nucleic acid analogues; 

  • High throughput sequencing, its use in uncovering genetic basis of disease and the prospect of personalised medicine; 

  • Alternatives to animal experiments; 

  • Epigenetics; 

  • Drugging protein-protein interactions; 

 

Disease areas 

  • Diseases of aging, particular neurodegenerative disorders (Alzheimer’s); 

  • The challenge of drug resistance – antibiotics and antivirals; 

  • Vector-borne disease (malaria); 

  • Diabetes and obesity; 

  • Respiratory disorders 

  • Breast cancer 

 

Commerce and regulation 

  • Models for funding drug discovery e.g. rare diseases, antibiotics; 

  • Outsourcing, contract research, virtual pharma; 

  • Initiatives for sharing of data and compounds; 

  • Repurposing existing drugs; 

  • Effect of intellectual property law on activity in the pharmaceutical industry. 

 


CHT356: Practical Medicinal Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT356
External Subject Code 100420
Number of Credits 10
Level L7
Language of Delivery English
Module Leader Dr Michaela Serpi
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module will involve the synthesis, purification and characterization of chemical compounds that have the potential to be inhibitors of medicinally important enzyme targets.  

 

You will work independently to plan and execute the synthesis of your target compounds learning how to use modern synthetic methods.  

 

Modern analytical techniques including NMR spectroscopy will be used to characterise the products. Groups will need to manage their time and resources in the laboratory and coordinate to produce a final report.  

 

The module will also include exercises designed to develop critical analysis, problem-solving, oral, and written communication, and to enhance your employability. 

On completion of the module a student should be able to

 

  • Plan a divergent synthetic strategy to efficiently obtain multiple compounds. 

  • Obtain and act upon safety and hazard information for chemicals. 

  • Perform a range of practical techniques in organic synthesis. 

  • Work as a team to efficiently execute multi-step synthesis of several compounds. 

  • Measure and interpret analytical data for small organic molecules. 

  • Use conventional synthesis and microwave-assisted reactions. 

How the module will be delivered

The module will consist of 5 x 7 hours laboratory sessions. The module will be delivered in the School’s teaching laboratories.  

 

Groups of you will be provided with guidance prior entrance in the laboratory by the module tutor at a scheduled meeting (1 x 2 hours). Demonstrators will provide guidance during laboratory sessions. 

Skills that will be practised and developed

Intellectual Skills: 

 

  • You will be able to draw conclusions about reaction mechanisms by combining experimental and spectroscopic data, developing analytical and critical thinking skills;  

  • You will be developing the ability to relate the experimental data to the underlying theory enhancing your critical thinking skills;  

  • You will analyse problems and identify the critical decisions needed in designing approaches to solutions, developing problem solving skills;  

 

Chemistry-Specific Skills: 

 

  • Practical skills in synthetic organic chemistry, in preparing, isolating, and purifying organic compounds using standard procedures; 

  • To have hands on experience of cutting-edge techniques such as automated, robotic microwave reactors and automated column chromatography systems; 

  • Interpreting NMR spectra of organic compounds and hence critically assess the outcome of a reaction; 

  • Using experimental data to calculate an unknown value; 

  • Assessing the risks associated with the use of chemicals and apparatus for themselves, the others, and the environment, which will help developing awareness of health and safety along with ethical, social, and environmental responsibilities; 

  • Recording experimental data in an organised manner and presenting a written report and oral discussion clearly and concisely, developing the ability to effectively communicate results; 

  • Determining the most appropriate format for presentation of experimental data acquiring impactful presentation skills; 

  • Showing scientific judgement and ability to select appropriate experiments to tackle a problem developing problem solving, analytical and independent critical thinking skills. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

  

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.   

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Graduate Attributes – Assessment:    

  

Practical Assessment                100% 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.   

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

  

Goal 3. Ensure healthy lives and promote well-being for all at all ages 

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development  

How the module will be assessed

You will be assessed for readiness to enter the laboratory by completing pre-lab assignments (which are assessed) to ensure compliance with safety and an understanding of what the experiment will involve. The learning outcomes will be assessed continuously based on written report, samples of compounds prepared, spectroscopic and analytical data, performance in the laboratory. Consistent attendance of practical sessions is essential. You will need to collate your lab records, observations NMR spectra, TLC analysis and submit in the post-lab write-up booklet which will also contain 1 or 2 questions on reaction mechanism and specifics about equipment. The individual report will be a detailed description of the experimental work performed by an individual student. Reports will be assessed by a module tutor. Students should present their experimental description and data in line with that which would be expected in a journal (for example, ACS Journal of Medicinal Chemistry; J. Med. Chem.). 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

Practical work cannot be repeated after the scheduled time for the module is over. Reassessment involves completing the written assessments based on the student’s own data. Students who need to repeat or do the laboratory work will be required to resit as an internal student in the next academic session. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Practical-Based Assessment 100 Practical Medicinal Chemistry N/A

Syllabus content

The topics will cover practical synthetic organic chemistry (preparation of a range of compounds on small and medium scale), with the use of cutting-edge synthesis tools/techniques. Compounds characterisation and analysis will include NMR, and other techniques as appropriate.  

 

 


CHT358: Biocatalysis for a Sustainable Future

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT358
External Subject Code 100344
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Dr David Miller
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

 

Biocatalysis is an interdisciplinary subject that sits at the cutting edges of chemistry, biology, and the sustainable production of industrially important chemicals. As we move to a net-zero economy ever more atom efficient and sustainable methods for fine chemical production are required. The material in this module will introduce and educate you on biocatalysts that are naturally occurring or engineered enzymes, which can catalyse transformations with high levels of regioselectivity, and stereoselectivity in particular but also on whole cell systems which point to future for recycling/reuse of human-generated waste and generate energy and fuels using renewable feedstocks. 

This module will first remind you of the structure of fundamental building blocks of life (primarily proteins and nucleic acids), as a prelude to understanding how the enzymes needed for biocatalysis are produced in large amounts. In addition, some basic principles of enzyme kinetics and catalytic mechanism will be revised. We will then bring you up to speed on the state-of-the-art in nucleic acid synthesis, amplification, and sequencing.  

You will be introduced to current methods of biotechnology for the production and manipulation of proteins that have applications spanning research, green manufacturing, and biopharmaceuticals. Problems with existing methods will be discussed and strategies for their solution will be presented.  

You will be shown the molecular basis for biocatalytic applications of a series of enzymes, such as proteinases, with an emphasis on methods for evaluating and controlling the stereochemical outcome of these transformations. 

Metabolically transformed microorganisms for the production of small molecules (e.g. citric acid and other amino acids) and antibiotics (e.g. penicillin and erythromycin) will be introduced. The principles of re-engineering the metabolic pathways present in microorganisms will be presented together with their use in optimizing the yields of target compounds.  

Finally, you will be shown how microorganisms can be used in environmental bioremediation and the conversion of biomass into high fructose corn syrup and biofuels. Problems with existing methods will be discussed and strategies for their solution will be presented. 

On completion of the module a student should be able to

 

  • Demonstrate a critical awareness of the place biocatalysis has within the biotechnology and chemistry toolkit, showing a comprehensive understanding of its advantages and disadvantages relative to other catalytic techniques.  

  • Evaluate and propose novel methods for the asymmetric generation of organic molecules using the toolkit of biocatalysis presented herein, when challenged with unseen problems.  

  • Propose solutions to unseen problems in biocatalysis through employment of a comprehensive knowledge of the principal types of organic transformations that can be catalysed by enzymes and/or whole-cell systems on the industrial scale.  

  • Demonstrate a systematic knowledge of methods for preparation of enzymes for biocatalysis and hence use creativity to propose appropriate production strategies for wild type and engineered biocatalysts.  

  • Demonstrate a comprehensive and systematic understanding of biocatalytic process including catalytic enzyme mechanism and cofactor regeneration associated with using enzymes outside of cells and apply this to novel challenges in biocatalysis.  

 

How the module will be delivered

A blend of online learning activities with face-to-face learning support and feedback. 

 

The module will be delivered over the autumn and spring semesters by 12 x 1-hour lectures and 2 x 1-hour tutorials supported by 2 x formative workshops in each semester. Some aspects may be delivered by pre-prepared video for supplementary support. 

 

The module tutors will each deliver material with the final exam featuring four questions sampling material from each tutor. Hence the formative workshop from each tutor will be aimed at supporting learning for their examination questions. 

 

The autumn semester exam period will feature an assessment worth 30% of the module mark to gauge student progress at this point. 

Skills that will be practised and developed

 

Academic Skills 

 

  • You will gain experience in project planning and problem-solving in the field of biocatalysis using both whole cells and isolated and purified enzymes. 

 

Chemistry Specific Skills 

 

  • You will gain experience in the evaluation of biocatalysis performance and limitations regarding a range of asymmetric synthetic transformations and kinetic resolutions. 

  • You will develop the skills required to create solutions to unseen problems in biocatalysis for the sustainable synthesis of organic chemicals from renewable feedstocks and propose strategies of the preparation and purification of biocatalysts. 

  • You will develop the knowledge and understanding necessary to explain the catalytic mechanism of a variety of biocatalysts and how their structures form and contribute to their activity. 

 

Employability skills: 

 

This module is delivered and aligns with the following University Graduate Attributes:  

  • Communicate complex ideas effectively to diverse audiences. 

  • Deliver, accept, and act on constructive feedback.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems. 

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen. 

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future. 

 

 

All module learning outcomes will be tested in the class tests and examinations. Formative assessments will be given by each tutor during module delivery in the form of tutorials and workshops to provide feedback and develop good practice. 

 

 

 

Sustainable Development Goals:  

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

  • Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture.  

  • Goal 3. Ensure healthy lives and promote well-being for all at all ages. 

  • Goal 12. Ensure sustainable consumption and production patterns. 

  • Goal 15. Protect, restore, and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss. 

    

 

How the module will be assessed

A written exam (70%) undertaken in the Spring assessment period will test the student’s knowledge and understanding as elaborated under the learning outcomes. A class test (30%) undertaken as an invigilated open-book examination-style assessment will allow the student to demonstrate their ability to solve problems, and to judge and critically review relevant information from the primary scientific literature and provide practice for the examination. Formative coursework problem sheet will give you practice in this assessment after each half of the delivered lecture material in each semester.  

Any academic or competence standards which may limit the availability of adjustments or alternative assessments for disabled students should be clearly stated in line with guidance provided in the Reasonable Adjustment Policy and Procedure  

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Class Test 30 Workshop problem sheet N/A
Exam - Spring Semester 70 Biocatalysis for a Sustainable Future 3

Syllabus content

All content is mandatory. 

Protein and RNA chemistry  

Protein and nucleic acid structure and function. 

Enzyme catalysis  

Active site structure and the molecular basis of catalysis, including the use of co-factors. The Michaelis-Menten model of enzyme kinetics  

Recombinant DNA technology  

Tools for the manipulation of DNA (endonucleases, ligases, DNA polymerases). Methods of DNA synthesis, amplification, and sequencing  

Obtaining enzymes in bacterial expression systems  

Isolation and purification of recombinant proteins. Modification of proteins by site-directed mutagenesis.  

Advanced topics in biocatalysis, use of enzymes to catalysis asymmetric organic transformations:  

Metabolic engineering, use of biomass as feedstocks and fermentation production of fine chemicals and biofuels. 

Use of enzymes in organic solvents. Cofactor chemistry and recycling strategies. Kinetic resolution and dynamic kinetic resolution.  

Directed evolution for the development of bespoke biocatalysis. 

Enzyme applications: 

  • Hydrolase enzymes – lipases, esterases, proteases etc. with specific examples and mechanism.  

  • Lyases – e.g. Aspartase, tyrosine-phenol lyase  

  • Isomerases – e.g. glucose isomerase  

  • Transferases – e.g. aminotransferases, PLP as cofactor  

  • Ligases  

  • Oxidoreductases – dehydrogenases, oxidases, oxygenases, peroxidases  

 


CHT359: Drug Discovery Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT359
External Subject Code 100420
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Professor Thomas Wirth
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

 

This module aims to give you an overview of the methods used by medicinal chemists for synthesis of molecules in drug discovery programmes. Common reactions used in drug discovery for preparation of molecules for structure activity relationship (SAR) studies will be presented. Technologies used to support high-throughput and parallel organic synthesis and purification will be described. Design of experiments, hit/lead identification and reaction screening will be introduced. You will have the opportunity to propose strategies for efficient synthesis of novel molecules with a desired biological activity.  

 

On completion of the module a student should be able to

 

  • Describe catalysts and reaction mechanisms for commonly used transformations in medicinal organic chemistry;  

  • Devise strategies for efficient preparation of series of related compounds for structure-activity relationship studies;  

  • Devise laboratory scale synthetic routes to novel biologically active organic molecules;  

  • Critically comment upon the challenges encountered medicinal chemistry to generate hit and lead compounds for further development;  

  • Apply reactions of carbon atom functionalisation (Pd-catalysis, oxidation, reduction) and nitrogen atom functionalisation (amide formation, multicomponent reaction, heterocycle formation) in drug discovery;  

  • Creatively devise new synthetic strategies for small molecule synthesis aimed at specific disease targets. I.e. antivirals, anticancer, antibiotics and neuroprotective drugs. 

How the module will be delivered

The module will consist of 24 x 1-hour lectures across both semesters (12 hours in in each), that will introduce the topics laid out in the syllabus. You will be expected to supplement these lectures with independent research of texts, specialist reviews and peer-reviewed literature and to discuss their findings in 4 × 1 hour formative tutorials. There will be workshops where you will be introduced to synthetic chemistry problems in a drug discovery context, followed by written submission of coursework.  

Skills that will be practised and developed

 

Academic skills:  

Ability to search and consult the literature and databases and provide synthetic meaningful solutions.  

Assess and solve problems in drug discovery together with their theoretical background and any strengths or weaknesses associated with them.   

Identification of chemical problems related to drug discovery. Several of the reactions used in drug synthesis are taking environmental and sustainability issues into consideration, the student can therefore demonstrate their skills in and awareness of these matters.  

Subject specific skills:  

Ability to analyse and discuss carbon and nitrogen atom functionalisations on a mechanistic level including some stereochemical aspects.  

Apply this understanding to solve previously unseen problems, therefore enabling the student to demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding.  

Develop the expertise to develop written communication skills and discuss key features of reactions related to drug synthesis.  

Employability skills:  

Discussions in tutorials will help to strengthen collaboration and effective communications skills.  

In discussing industrial processes related to drug synthesis and drug discovery in this module, the student also can develop their commercial awareness skills. 

 

 

Employability skills:     

This module is delivered and aligns with the following University Graduate Attributes:   

 

  1. Be respectful of the roles of others and acknowledge the limits of their own skills/experience. 

  1. Listen to and take account of the views of others. 

  1. Communicate complex ideas effectively to diverse audiences. 

  1. Contribute to discussions, negotiate and present with impact. 

  1. Consider own personal and professional ethical, social and environmental responsibilities. 

  1. Demonstrate personal and professional integrity, reliability and competence. 

  1. Understand organisations, their stakeholders and their impact on the community. 

  1. Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  1. Understanding organisations, their stakeholders and their impact on the economy 

  1. Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Sustainable Development Goals:       

    

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

  • Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture  

  • Goal 3. Ensure healthy lives and promote well-being for all at all ages 

 

How the module will be assessed

Written Exam, Workshop   

 

The workshop and the written exam will focus on different topics due to the timing of these events. They will enable you to demonstrate that you have achieved the learning outcomes.   

 

There will be formative workshops from each module tutor covering practice material that will prepare you for the assessed material. 

 

Marking criteria will involve the validity of the provided answers to set questions and the ability of the student to handle unknown material connected to the course content allowing the student to demonstrate their ability to independently investigate problems and offer effective solutions.  

 

Further details (dates) are found in the assessment map.   

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:   

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session.  

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 30 Workshop N/A
Exam - Spring Semester 70 Drug Discovery Chemistry 3

Syllabus content

  1. Sources of compounds for drug discovery: natural products, compound collections, existing drugs.  

  1. Reactions for drug discovery chemistry: palladium catalysed cross couplings, acylation, alkylations, sulfonamide formation, SNAr, reductive amination and multicomponent reactions; hydrogenation, amide formation; heterocyclic compounds synthesis, reactivity and properties.   

  1. Introduction to structure activity relationships.   

  1. Drug discovery process.  

  1. Antibacterial agents 

  1. Antiviral agents 

  1. Anticancer agents 

  1. Drugs acting on the nervous system. 


CHT542: Metals in Medicine and Bioimaging.

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT542
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Dr Benjamin Ward
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module will cover modern aspects of inorganic coordination chemistry, including the design of d- and f-block coordination complexes and metal-based nanoparticles for application in bioimaging techniques and medicine. It will set out the ways in which ligands and complexes can be designed to achieve desired properties and functionality. It will examine a range of bioimaging techniques (including, magnetic resonance imaging, radioimaging and luminescence microscopy), including their underlying principles, and show how different metal complexes can be designed for these applications. Aspects of synthesis, spectroscopic characterisation and molecular design will be described, as will ways to rationalise the relationship between structure and function. This will lead to the description and case study analysis of responsive probes, bimodal systems, biological targeting, and theranostic agents. 

On completion of the module a student should be able to

Describe synthetic chemistry pathways to target ligands, complexes and nanoparticles. 

Interpret spectroscopic and physical data and appreciate how variations in structure relates to function in different biological contexts.     

Appreciate the design of metal-based species for biological environments, and how this influences the design of supporting ligands and nanoparticles. 

Describe the fundamental concepts and principles, and the advantages and disadvantages, associated with different bioimaging techniques 

Critically analyse literature-based examples thereby demonstrating a knowledge of the design criteria of metal-based agents for biological applications 

How the module will be delivered

Content will be delivered primarily using lectures.  

Formative workshops will be used to discuss case studies from the literature, enhance and assess problem-solving skills related to the critical analysis of data, and demonstrate application of knowledge. 

Skills that will be practised and developed

Academic Skills:  

  • Interpret complex scientific information and relate to properties of different classes of coordination complexes 
  • Understanding what kind of information is provided by different bioimaging techniques  
  • Develop effective skills focussed upon reviewing primary literature and extracting relevant    information  

Chemistry-Specific Skills: 

  • You will appreciate ligand structure and bonding in metal complexes and be able to apply concepts of targeted molecular design to more complicated scenarios;  
  • You will learn how to analyse datasets and to formulate an explanation for observations of physical properties, thereby developing a level of understanding closer to situations expected in graduate-level employment.   
  • You will refine your problem-solving skills in situations that require them to synthesise a coherent argument or explanation using knowledge/data from a number of different sources.  

Employability skills:     

   This module is delivered and aligns with the following University Graduate Attributes:   

  • Contribute to discussions, negotiate and present with impact. 
  • Consider own personal and professional ethical, social and environmental responsibilities. 
  • Demonstrate personal and professional integrity, reliability and competence. 
  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 
  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 
  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 
  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 
  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 
  • Actively reflect on own studies achievements and self-identity 
  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 
  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 
  • Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future.  

Graduate Attributes – Assessment:     

Exam           70% 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 
  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 
  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 
  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 
  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Written assessment             30% 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information, including primary literature. 
  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 
  • Investigate problems and offer effective solutions 
  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change 
  • Identify and articulate own skills, knowledge and understanding confidently 

Sustainable Development Goals:       

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

  • Goal 3. Ensure healthy lives and promote well-being for all at all ages 
  • Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

How the module will be assessed

Summative coursework assessment (30%) workshop is a take-home assessment that requires engagement and analysis of the primary literature – it is a word count limited written report. This will assess your ability to use electronic databases, locate relevant scientific information and critically review the primary literature. This will assess your knowledge of molecular design and a deep understanding of the physical parameters that dictate the biological potential and application of your chosen system.   

A written exam (3 hour, 70%) will test your ability to demonstrate your deep knowledge and understanding of the syllabus content, and your ability to apply the techniques/concepts covered to unseen problems.   

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 30 Written Assessment N/A
Exam - Spring Semester 70 Metals in Medicine and Bioimaging. 3

Syllabus content

Fundamental aspects of coordination chemistry in medicine: solubility products, formation constants,  ligand pKa, coordination complexes of d- and f-block metal ions; organometallic and cyclometalated complexes; understanding biocompatibility, targeted design, bioconjugation and responsive systems 

Ligand design: chelating, multidentate and macrocyclic variants, siderophores, bioconjugation 

Optical imaging using Luminescence   

Background on confocal fluorescence microscopy for cellular imaging  

Background on photophysics – Stokes shift, Jablonski diagrams, time resolved vs steady state measurements, quenching pathways, types of emission, tuning emission through ligand design.  

Types of transition metal-based luminophore. Types of lanthanide(III)-based compounds. Upconverting nanoparticles.  

Magnetic Resonance Imaging and Contrast Agents  

Background on magnetic resonance imaging. Background on the fundamental properties and design of T1 and T2 contrast agents. Pulse sequences. Types of complexes used for T1 and T2 contrast. Assessing new contrast agents –solubility, stability and the NMRD. Molecular agents and nanoparticle systems. 

Gamma Radio-Imaging via SPECT and PET   

Background to gamma imaging – physical basis of the techniques, data capture and imaging.  
Single Photon Emission Tomography (SPECT). Positron Emission Tomography (PET). 
General properties of PET/SPECT isotopes, half-lives, imaging resolution, biological matching. 

Background to functional imaging vs. structural imaging. Types of molecular agents. 

Multimodal Imaging agents 

Understanding design principles and critical analysis of applications 


CHT543: Molecules for Health and Life

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT543
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Professor Thomas Wirth
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module will describe modern aspects of organic, biological and medicinal chemistry. It will introduce advanced methods for control in the synthesis of target molecules. It will explain in detail how preparation of enantiomerically pure molecules is achieved, for example in pharmaceuticals, and describe development of stereoselective reactions as well as various enabling technologies. It will set out how molecular synthesis can be targeted towards specific applications, such as medicinal chemistry or sustainability. It will also explain application of biophysical techniques to study interactions in biological and medicinal chemistry research, and methods for simulation of molecules of importance to life and health 

On completion of the module a student should be able to

 

  • Apply the range of synthetic methods, strategies and reagents encountered to solve unseen problems using creativity to challenging synthetic targets, including enantiomerically pure molecules.  

 

  • Identify, using critical analysis, the main principles in the use of enabling reaction technologies and related industrial issues together with application to target molecules. 

 

  • Use critical awareness of the key inter- and intra-molecular interactions that determine biomolecular structure and drug-receptor binding to propose sustainable solutions to unseen problems in organic synthesis. 

 

  • Demonstrate creativity and critical awareness in the application of technique(s) appropriate to study interactions between biomacromolecules and between biomacromolecules and small molecules.  

 

  • Demonstrate a comprehensive knowledge molecular modelling methods suitable for study of problems in medicinal and biological chemistry to solve unseen problems and critique peer-reviewed published material. 

 

  • Interpret and critically assess the results from biophysical and computational techniques.  

 

How the module will be delivered

Content will be delivered through a combination of approaches, including lectures, pre-recorded content and problem-solving workshops. Contact time, in the form of lectures or problem-solving workshops, is 40 h across two semesters, equating to approximately two sessions per week. Support for learning will include informal ad hoc formative tests.  

  

Workshops and tutorials will be used to enhance and assess problem-solving skills related to the retrieval and analysis of data. 

 

Skills that will be practised and developed

 

 

Chemistry -Specific Skills: 

 

  • You will develop a detailed understanding of how molecular structures are related to their specific usages, and how these structures can be formed through organic synthesis   

 

  • Approaches to evaluate the success of molecules addressing targets of biological interest will be discussed and the accompanying data analysis approaches will be developed. 

 

  • The module will also involve a large element of problem solving using both numerical and algebraic techniques, based around real examples of experimental and theoretical data. 

 

Employability skills:     

   

This module is delivered and aligns with the following University Graduate Attributes:   

 

  • Contribute to discussions, negotiate and present with impact. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Actively reflect on own studies achievements and self-identity 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future.  

  

All learning outcomes will be assessed within the class test and examination.  The class test will assess and be appropriate to the material delivered in the Autumn semester.  Formative assessments in the form of tutorials and workshops will provide feedback and supplement feedback in good practice provided from the class test results. 

 

 

   

 

Sustainability Development Goals:       

    

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

  • Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture  

  • Goal 3. Ensure healthy lives and promote well-being for all at all ages 

  • Goal 6. Ensure availability and sustainable management of water and sanitation for all 

  • Goal 7. Ensure access to affordable, reliable, sustainable and modern energy for all 

  • Goal 8. Promote sustained, inclusive and sustainable economic growth, full and productive employment and decent work for all 

  • Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

How the module will be assessed

A written exam (2 h) will test your ability to demonstrate your knowledge and understanding of the syllabus content, and your ability to apply the techniques/concepts covered to unseen problems. A single piece of coursework will allow you to demonstrate knowledge of key concepts and apply that knowledge to chemical problems. Marks will reflect the extent to which you have met the module learning outcomes shown above. Formative assessments will take the form of workshop and tutorial assignments and be delivered by each module tutor and will provide feedback (alongside the coursework feedback) to inform you of your progress and in good practice. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

Assessment Breakdown

Type % Title Duration(hrs)
Class Test 30 Coursework - Class Test N/A
Exam - Spring Semester 70 Molecules for Health and Life 3

Syllabus content

Organic synthesis, stereoselective functionalisation of double bonds, electrophilic reagents.  Applications in total synthesis and the synthesis of bioactive compounds.  

 

Enabling Tools for Organic Synthesis: microwave reactors, photochemical reactors, electrochemistry and flow chemistry.  

 

Molecular recognition in biology. Biomolecular interactions, structure of essential building units. Supramolecular chemistry in biotechnological applications. 

 

Biophysical techniques: key principles of spectroscopies used in biophysical studies. Calorimetry: DSC and ITC. Surface-based techniques in biophysical chemistry; electrochemical approaches to studying interactions. Data acquisition and interpretation, analysis and estimation of error margins. 

 

Supramolecular chemistry: molecular cages, surface self-assembled networks and metal-organic frameworks, and their applications in sensing and storage.  

 

Supramolecular chemistry in biology: nucleic acid and protein as well as their applications, spanning form small molecule synthesis, artificial enzyme design and antibody-drug conjugate creation.  

 

Molecular modelling for molecules of life: parameterised methods, potential energy surfaces, forces, local and global optimisation, dynamics 

 


CHT544: Modern Materials

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT544
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Dr Alison Paul
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

  • The module aims to develop an understanding of the synthesis, formulation, characterisation, simulation of advanced materials relevant to the development of materials for modern world applications.  

  • It will set out how modern chemistry goes beyond the single molecule, analysing the driving forces for the association between molecules and/or ions that are induced by non-covalent bonding interactions in solution, solid-state and at interfaces. Relating these qualities to bulk material behaviour through the understanding of important structure – property relationships, the module will link fundamental principles to the informed design of modern materials, including consideration of potential commercial feasibility and reduction of environmental impact. 

  • It will describe materials such as nanoparticles, colloidal systems, crystalline and amorphous solids, and supramolecular architectures in 2- and 3-dimensions. The course will set out methods for determining and modelling their structural, dynamic, and electronic properties, including static, time-resolved and spatially resolved analyses. 

 

On completion of the module a student should be able to

 

  • Describe how different methods for synthesising and formulating advanced materials can impact on their performance in different applications.   

  • Evaluate and predict key properties of materials based on modelling and characterisation data.  

  • Analyse experimental/characterisation/modelling data for different advanced materials to probe the material properties and establish an understanding between structure, composition, and chemistry.  

  • Explain the importance of time-resolution and spatial-resolution in analytical measurements on modern materials and describe what additional information these methods provide in comparison to static techniques. 

  • Explain key concepts of molecular recognition in biology and apply these to the structure and function of biomaterials.  

  • Critically assess literature relating to advanced materials properties and applications. 

 

How the module will be delivered

  • Content will be delivered primarily via lectures (40 h across two semesters, equating to approximately two lectures per week). Lectures will include discussion activities, worked problems and informal ad hoc formative tests.  

  • Workshops and tutorials will be used to enhance and assess problem-solving skills related to the retrieval and analysis of data. 

Skills that will be practised and developed

Chemistry-Specific Skills:  

 

  • Applying ideas from fundamental chemistry to identify how properties of molecules, solids and surfaces are utilised in the design of modern materials with specific target properties. 

 

  • You will practise data interpretation skills, extending your skills to multi-component systems. 

 

  • You will develop a detailed understanding of how properties of molecules and materials are related to their electronic structure, and how these properties are related to observed behaviour and spectra.   

 

  • The module will also involve a large element of problem solving using both numerical and algebraic techniques, based around real examples in materials chemistry. 

 

Employability skills:     

   

This module is delivered and aligns with the following University Graduate Attributes:   

 

Contribute to discussions, negotiate and present with impact. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Actively reflect on own studies achievements and self-identity 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future.  

  

Graduate Attributes – Assessment:     

   

Exam:              70% 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Written assessment:  30% 

  • Contribute to discussions, negotiate and present with impact. 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Sustainable Development Goals:       

    

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

  • Goal 8. Promote sustained, inclusive and sustainable economic growth, full and productive employment and decent work for all 

  • Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

  • Goal 11. Make cities and human settlements inclusive, safe, resilient and sustainable 

  • Goal 13. Take urgent action to combat climate change and its impacts 

How the module will be assessed

A written exam (3 h) will test the student’s ability to demonstrate their knowledge and understanding of the syllabus content, and their ability to apply the techniques/concepts covered to unseen problems. A single piece of coursework will allow you to apply knowledge to chemical problems through critically assessment and evaluation of methods for the synthesis, characterisation and application of materials, thereby demonstrating knowledge and understanding of key concepts. Marks will reflect the extent to which you have met the module learning outcomes shown above. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

Assessment Breakdown

Type % Title Duration(hrs)
Class Test 30 Coursework - Class Test N/A
Exam - Spring Semester 70 Modern Materials 3

Syllabus content

 

Self-assembly and self-organization in colloidal formulations of surfactants, polymers and particles. Structure activity relationships and interaction between components in formulations, including supporting case studies. Advanced methods for the characterisation of nanoscale structure and bulk properties. Applications in industry and healthcare. 

 

Thermodynamics and kinetics of host-guest processes of biomacromolecules. Non-covalent interactions in solid-state and solution. Dynamic covalent bonds & supramolecular polymers. Molecular machines.  

 

Experimental techniques and methods for nanoscale and ultrafast chemistry for supramolecular processes. 

 

Fundamental properties of advanced materials in technological applications. Properties and applications of semiconducting materials, and the impact of defects. Properties of interfaces and surfaces on geometric, energetic and electronic properties.  

 

Simulation of materials. Atomistic and electronic structure methods. Calculation of static, dynamic and electronic properties of solids. Periodic density functional theory and forcefield approaches.  

 


CHT545: Catalysis and Interfaces for Sustainable Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT545
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Dr Jennifer Edwards
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module will cover the synthesis, characterisation and simulation of the catalytic materials that find applications in the development of sustainable chemicals production and energy sectors.  

 

The need to reduce our dependence on fossil sources of carbon for chemicals and fuels is giving rise to a whole new set of challenges in catalysis. The module will introduce pathways used to transform renewable resources into useful chemicals and emphasize how characterisation and simulation lead to understanding which helps to design and optimise catalytic materials.  

 

It will also address current issues in environmental chemistry, including use of catalysis to address clean air, water and energy generation. It will explain how fundamental properties of solids, surfaces and nanoparticles can be related to catalytic activity.  

 

You will develop critical analysis skills through study of literature case studies and quantitative approaches to defining how environmentally friendly a chemical process really is. 

On completion of the module a student should be able to

  • Appreciate the fundamental principles of structure, function and activity of heterogeneous catalysts in modern catalytic processes, Green Chemistry and energy sectors. 

  • Evaluate experimental data from catalysts performance experiments and relate this to physical and chemical information describing catalyst structure and then use this to propose a catalytic mechanism solution. 

  • Describe common structural features of heterogeneous catalysts and how these relate to activity. 

  • Appreciate the range of techniques that can be used to characterise catalyst and surface structures, and how these can be used to explain and predict activity. 

  • Work with kinetic rate equations to interpret catalytic data giving conversion and selectivity as a function of time.  

  • Describe in situ measurements that are used to scope out elementary surface reactions during catalysis. 

  • Identify the main computational chemistry approaches used in the simulation of catalytic materials and catalysed reactions. 

  • Explain how computer simulation is applied to map out reaction energetics for key steps in heterogeneously catalysed reactions. 

 

How the module will be delivered

 

  • Content will be delivered primarily using lectures (40 h across two semesters, equating to approximately two lectures per week). In addition, lectures will include worked problems and informal ad hoc formative tests.  

  • Workshops and tutorials will be used to enhance and assess problem-solving skills related to the retrieval and analysis of data. 

Skills that will be practised and developed

 

Chemistry-Specific Skills: 

 

  • Applying ideas of catalysis to appreciate how catalytic systems can be designed and interrogated using experimental and simulation techniques.  

  • You will develop a detailed understanding of how properties of materials are related to their catalytic activity, and how these properties can be controlled.  

  • The module will also involve a large element of problem solving using both numerical and algebraic techniques, based around real examples of theoretical methods. 

  • The module is centred in sustainable chemistry, and you will also acquire the vocabulary and analytical skills to exercise critical judgement regarding the contribution a particular catalytic process can make to improving the environment and reducing the impact of anthropogenic activity. 

 

Employability skills:     

   

This module is delivered and aligns with the following University Graduate Attributes:   

 

Contribute to discussions, negotiate and present with impact. 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Actively reflect on own studies achievements and self-identity 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future.  

  

Graduate Attributes – Assessment:     

   

Exam               70% 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Written assessment                30% 

  • Contribute to discussions, negotiate and present with impact. 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

Sustainable Development Goals:       

    

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

  • Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture  

  • Goal 3. Ensure healthy lives and promote well-being for all at all ages 

  • Goal 6. Ensure availability and sustainable management of water and sanitation for all 

  • Goal 7. Ensure access to affordable, reliable, sustainable and modern energy for all 

  • Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation 

  • Goal 12. Ensure sustainable consumption and production patterns 

 

How the module will be assessed

A written exam (3 h) will test your ability to demonstrate your knowledge and understanding of the syllabus content, and your ability to apply the techniques/concepts covered to unseen problems. A single piece of coursework will allow you to demonstrate knowledge of key concepts and apply that knowledge to chemical problems. Marks will reflect the extent to which you have met the module learning outcomes shown above. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

Assessment Breakdown

Type % Title Duration(hrs)
Class Test 30 Coursework - Class Test N/A
Exam - Spring Semester 70 Catalysis and Interfaces for Sustainable Chemistry 3

Syllabus content

 

The module will cover the synthesis of catalytic materials which can underpin sustainable chemicals and energy sectors. The principals of Green Chemistry will be reviewed with current literature examples of industrial processes that have been superseded by more sustainable chemistry. The characterisation methods used to measure properties such as the solid phases present, the effective surface area of catalysts and spectroscopic inspection of working catalysts will be addressed alongside high-resolution microscopy capable of giving atomic level images of catalytic materials. The main approaches to the computer simulation of catalytic materials will also be introduced, with examples that integrate with the theme of Sustainable Chemistry drawn from the literature. Reaction schemes will be presented and discussed based on calculated potential energy surfaces and the insights these given into the catalytic processes they represent. The overall aim of the module is to demonstrate how materials characterisation and simulation can help to inform a mechanistic understanding of heterogeneous catalysis using key reactions as exemplars.    

 


CHT546: Frontiers in Inorganic Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT546
External Subject Code 101043
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Dr Benjamin Ward
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module will focus on the structure, influence, and design of ligands and compounds in the development of functional metal complexes and main-group compounds.  Four areas will be covered, representing a cross section of pertinent problems in this area, these will be a) metal complexes for catalytic polymerisation and depolymerisation; b) the study of N-heterocyclic carbene complexes and their catalytic chemistry; and c) the stoichiometric and catalytic reactions of frustrated Lewis pairs; d) advanced aspects of homogeneous catalysis for sustainable chemical synthesis.  The module will cover the synthesis of ligand precursors, coordination chemistry, including in cases where there is no electronic preference to coordination geometry, and homogeneous catalysis.  Attention will be given to the analysis of structure-activity relationships and the interpretation of catalytic data in terms of reaction mechanisms. The module highlights the use of inorganic chemistry for sustainable chemical processes and aligns with UN STGs 9, 12, 13, 14, and 15. 

On completion of the module a student should be able to

  1. Formulate a catalytic reaction mechanism within unfamiliar operating parameters (e.g. catalyst and/or substrate structure). 

 

  1. Critically evaluate catalytic reaction data in terms of the likely reaction mechanism, substrate structure, and catalyst design; assess structure-reactivity effects of ligands and formulate reactivity patterns. 

 

  1. Design an appropriate synthetic strategy for ligands and complexes within provided constraints. 

 

  1. Choose appropriate analytical techniques to characterise chemical species and assess analytical data in terms of chemical structure. 

How the module will be delivered

 

The module will be delivered in 20 2-hour lectures and four 1-hour tutorials. 

The module consists of four distinct blocks, each covering a different aspect of advanced inorganic and coordination chemistry. The four blocks will mirror the three sections described above: (a) the production and chemical recycling of polymers, including traditional polyolefins and modern alternatives; (b) metal complexes bearing N-heterocyclic carbene ligands in catalysis for sustainable chemical synthesis; (c) the role of frustrated Lewis pairs in catalysis; and (d) modern aspects of coordination chemistry relating to catalysis. Each block will be followed by a tutorial in which problem-solving and analytical skills are practised. 

 

Skills that will be practised and developed

Chemistry-specific skills: 

 

  • Learn how to analyse complex datasets and to formulate an explanation for trends and observations of chemical reactivity patterns.  

  • Develop the ability to relate the fundamental properties of functional metal complexes to a modern understanding of sustainable chemistry. 

  • Learn how to construct a cost-benefit analysis of making chemical processes aligned to the UN Sustainable Development Goals.  

  • Develop problem-solving skills in situations that require them to synthesise a coherent argument or explanation using knowledge/data from several different sources, particularly relating to chemical processes involving metal complexes. 

 

Employability skills: 

 

This module is delivered and aligns with the following University Graduate Attributes:  

 

  • Consider own personal and professional ethical, social and environmental responsibilities. 

  • Demonstrate personal and professional integrity, reliability and competence. 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Actively reflect on own studies achievements and self-identity 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

  • Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future.  

 

Graduate attributes – assessment: 

 

Exam (70%) 

 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Written assessment (30%) 

 

  • Contribute to discussions, negotiate and present with impact. 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information. 

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Demonstrate resilience, adaptability and creativity in dealing with challenges, and be open to change. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

Sustainable development goals: 

 

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialisation and foster innovation. 

Goal 11. Make cities and human settlements inclusive, safe, resilient and sustainable. 

Goal 12. Ensure sustainable consumption and production patterns. 

Goal 13. Take urgent action to combat climate change and its impacts. 

Goal 14. Conserve and sustainably use the oceans, seas, and marine resources for sustainable development. 

Goal 15. Protect, restore and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse biodiversity loss. 

 

 

How the module will be assessed

 

Formative assessment will be provided in the three tutorial sessions following each of the four theory blocks. These tutorials will be interactive and will develop the problem-solving skills required to apply the core lecture material to unfamiliar situations. 

Summative assessment will take the form of coursework (30%) and written examination (70%). Coursework will consist of a single piece of work of three 10-mark questions; each question will be problem-based and will require students to apply concepts of ligand design to synthesise catalytic mechanisms within unfamiliar operating parameters. This will allow students to meet learning objectives 1 and 2. 

The examination will consist of four 20-mark questions; students must answer any three. Questions will probe students’ ability to interpret data and to construct mechanistic arguments based on provided data, thus allowing students to meet learning objectives 3-4. 

Marking criteria 

50-60 Satisfactory appreciation of the key concepts of catalyst design and their structural influence on catalytic reactions. Work in this category will demonstrate the ability to design catalytic cycles to an unfamiliar substrate and/or catalyst that are similar (but not identical) to those given in lecture material. There will also be a demonstrable ability to construct a ligand and/or catalyst synthesis from the molecular types illustrated in the lecture material. 

60-70 Good grasp of most concepts relating to catalyst performance in relation to catalyst and substrate structure. Will demonstrate the ability to relate material from across all areas of the course to synthesise a rational explanation for catalyst performance and chemical reactivity. Will be able to propose a more advanced chemical synthesis pathway and an appreciation for how analytical techniques can aid the understanding of catalyst performance. 

70-100 Excellent demonstration of catalyst design and structural influence on catalytic reactions. An outstanding ability to make connections between different areas of knowledge to aid a thorough interpretation of unfamiliar data, providing a rigorous spectroscopic/mechanistic/structural analysis. The ability to demonstrate appropriate weighting in different parameters that can affect chemical reactivity as applied to an unfamiliar situation. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

The resit examination will adopt the same format as the main examination but will contain questions that allow students to demonstrate learning objectives 1-4. 

 

Assessment Breakdown

Type % Title Duration(hrs)
Written Assessment 30 Written Assignment N/A
Exam - Spring Semester 70 Frontiers in Inorganic Chemistry 3

Syllabus content

 

The applications of ligand design and coordination chemistry to a range of areas, including catalysis and p-block chemistry, with an emphasis on the ability of controlling the properties and reactivity of metal complexes by ligand design. 

The past and future of polymerisation catalysis 

A detailed mechanistic understanding of the properties and reactivity of d0 metal alkyl and alkyl cations will be discussed.  These complexes have most widely studied in the context of alkene polymerisation, and this type of reactivity will be used to exemplify the reactivity of d0 complexes.  The level of detail moves on from that covered in level 6, encompassing the catalyst structures required for the production of stereospecific polymers and the influence of agostic interactions to facilitate migratory insertion reactions.  This theme will be expanded to introduce the polymerisation of cyclic esters, commonly used as biodegradable polymers, and then ultimately to the forefront of polymerisation research where ring-opening co-polymerisation of CO2/epoxides and anhydrides/epoxides will be covered in detail. Approaches for depolymerisation catalysis by metal complexes will be covered. 

Heterofunctionalisation catalysis 

The role of d0metal complexes as catalysts for a range of organic transformations will be discussed, with particular focus on hydroamination, hydrogenation, hydrosilylation, and hydrophosphination.  A particular focus will be given to looking at the mechanisms of these reactions, for which there are less reaction steps possible (e.g. oxidative addition is precluded). This theme will be expanded to cover alkaline earth metals in catalysis, including their environmental benefits, their scope, and their limitations. 

Homogeneous catalysis in the 21st century 

This part of the module considers how established homogeneous catalytic systems can be improved in terms of both cost and environmental impact.  In particular, application of the principles of ‘green catalysis’ will be emphasised with regard to the nature of the catalyst, the chemical process itself and greener alternatives to established materials. The development of N-heterocyclic carbenes will be discussed, in relation to their synthesis, coordination chemistry, and catalytic applications. Comparisons will be drawn between NHC complexes and those bearing alternative ligands. 

p-Block organometallics 

Introduction to p-block organometallics, including structure and reactivity trends will be provided. This will lead to a detailed discussion of frustrated Lewis pairs (FLPs), and their role in catalysis. 


CHT548: Sustainable Energy

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT548
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Dr Stefano Leoni
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

 

The aim of this module is to present a blend of fundamental principle of energy conversion around sustainable energy, which encompasses various forms of energy production and consumption that are in place to minimize negative environmental impacts while meeting present and future energy needs. Overall, this module will emphasise how the current understanding of sustainable energy entails a holistic approach that integrates technological innovation, policy support, and societal engagement to achieve a more sustainable and resilient energy system for reduced environmental impact and scalability of energy production. The module will cover topics around: Renewable Energy Sources, Energy Efficiency, Decarbonization, Energy Storage, Smart Grids, Policy Support, Circular Economy, Community Engagement.  

 

 

On completion of the module a student should be able to

 

Explain key concepts of energy conversion and demonstrate a comprehensive understanding of how this is bound by fundamental laws. 

 

Show comprehensive understanding of chemical and physical processes governing energy transfer and conversion processes through application to the solution of unseen problems. 

 

Understand how to creatively apply thermodynamic and kinetic concepts to identify key problems in current energy production/conversion approaches. 

 

Demonstrate thorough knowledge on current bottlenecks in decarbonisation and the need to develop efficient processes of energy conversion, including catalytic processes and selection of precursors and raw materials. 

 

Critically evaluate the difference between linear and circular economy, including the ability to assess a process for its energy degrading impact. 

 

Demonstrate comprehensive knowledge of key processes of renewable energy production, including photovoltaic, photocatalytic and conversion of mechanical energy. 

 

Critically evaluate how an energy policy shift is linked to concepts of circular economy, and how basic science and research can affect societal decision making. 

 

Critically assess a process as zero-emission or carbon neutral or sustainable.  

  

How the module will be delivered

40 x 1 h lectures, 4 x 1 h tutorials and 4 x 1 h workshops. Lectures will deliver the core course content, addressing all learning outcomes. Formative workshops and tutorials will selectively address learning outcomes, with emphasis on problem solving and forging links between topics.  

Workshops will be designed around key concepts or technologies, including case studies and will provide formative feedback to inform you of your progress and develop good practice.  

Skills that will be practised and developed

Skills developed through formal module learning outcomes and summative assessment include: 

 

Academic skills 

  • You will gain skills in the interpretation of complex scientific information to interrelate energy conversion theory and processes to larger systems. 

  • You will gain the critical awareness to assess energy generation systems on micro and macroscale for their sustainability potential. 

  • Develop effective skills focussed upon reviewing primary literature and extracting relevant    information  

 

 

Chemistry Specific Skills 

  • You will gain a comprehensive understanding of thermodynamics and kinetic details processes and materials used to generate or convert energy. 

  • You will learn how to critically assess an energy generation or conversion process for its circularity and have a critical awareness of the ultimate sources of energy. 

  • You will be able to relate sustainable chemical energy generation processes to the societal policies and economic challenges that sustainable energy processes require and evaluate steps necessary to achieve change. 

 

   

 

All learning outcomes will be assessed within the class test and examination.  The class test will assess and be appropriate to the material delivered in the Autumn semester.  Formative assessments in the form of tutorials and workshops will provide feedback and supplement feedback towards good practice provided from the class test results. 

 

Employability Skills 

You will have the opportunity to develop the following Cardiff University Graduate Attributes which will help you become: 

 

Effective communicators 

  • Deliver, accept and act on constructive feedback 

 

Ethically, Socially and Environmentally Aware 

  • Consider own personal and professional ethical, social and environmental responsibilities 

  • Demonstrate personal and professional integrity, reliability and competence 

  • Understand organisations, their stakeholders and their impact on the community 

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals 

 

Independent and Critical Thinking 

  • Identify, define and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures 

 

Innovative Enterprising and Commercially Aware 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems  

  • Understanding organisations, their stakeholders and their impact on the economy 

 

Reflective and resilient 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts 

  • Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future 

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning.  

 

 

Sustainable Development Goals: 

 

This module is delivered and aligns in working towards the following Sustainable Development Goals: 

 

  • Goal 7 – Affordable and Clean Energy - Ensure access to affordable, reliable, sustainable and modern energy 

  • Goal 9: Build resilient infrastructure, promote sustainable industrialization and foster innovation 

  • Goal 11: Make cities inclusive, safe, resilient and sustainable 

  • Goal 12: Ensure sustainable consumption and production patterns 

  • Goal 13: Take urgent action to combat climate change and its impacts 

 

 

 

How the module will be assessed

Small-group tutorials will provide formative feedback, allowing students the chance to assess their competence. Formative workshops will be used to enhance this process. A January class test (1.5 hr) will provide 30% of the credit, and will allow students the chance to assess their progress and calibrate their performance.  A final exam (2 hr) at the end provides the bulk (70%) of the summative assessment. 

  

Tutorials and formative workshops will allow students to develop problem solving associated with the syllabus, and incorporate material being taught at the time. 

  

The January class test will assess material taught in the Autumn semester, with the end of module exam addressing all the learning outcomes. 

 

Both elements of summative assessment – the examination and the class test – consist of a variety of questions which test a candidate’s knowledge and understanding of concepts, and their ability to deploy those concepts on unseen problems.  The portfolio of questions are constructed so that some parts can be answered with a basic level of knowledge and understanding, and other parts support the demonstration of deeper understanding and capability. 

 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

Please provide information to the student about the opportunity for reassessment, should they fail the Module. You should explain the format that reassessment.  

 

If the reassessment is in a different format to the original assessment, you will need to show how it continues to meet the module level learning outcomes. 

 

Assessment Breakdown

Type % Title Duration(hrs)
Class Test 30 Class Test N/A
Exam - Spring Semester 70 Sustainable Energy 3

Syllabus content

 

The module will articulate the topic of renewable/sustainable energy over eight key topics, including: 

 

  1. Renewable Energy Sources: Sources like solar, wind, hydroelectric, geothermal, and biomass. The focus is on converting these sources to generate electricity and heat. 

  1. Energy Efficiency: Improving energy efficiency in all sectors, including buildings, transportation, industry, and agriculture, is crucial for reducing overall energy demand and minimizing/repurpose waste. 

  1. Decarbonization: Transitioning away from fossil fuels, which are major contributors to greenhouse gas emissions, towards low-carbon and carbon-neutral alternatives. This involves promoting electric vehicles, green building practices, and sustainable agriculture. 

  1. Energy Storage: Developing efficient and scalable energy storage technologies to overcome the intermittent nature of renewable energy sources like solar and wind. Batteries, hydro storage, and emerging technologies like hydrogen storage play important roles in this regard. 

  1. Smart Grids: Implementing smart grid technologies to improve the flexibility, reliability, and efficiency of energy distribution and consumption. This involves integrating advanced communication and control systems with the existing electrical grid infrastructure. 

  1. Policy Support: Supportive policies and regulations at local, national, and international levels to incentivize investments in sustainable energy technologies, promote research and development, and facilitate market adoption. 

  1. Circular Economy: Principles of a circular economy to minimize waste and maximize resource efficiency across the entire lifecycle of energy systems, from production and distribution to consumption and disposal. 

  1. Community Engagement: Community participation and empowerment in sustainable energy initiatives, including decentralized energy generation, energy cooperatives, and citizen-led advocacy for renewable energy projects on small scales. 

 


CHT550: Application of Research Methods

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT550
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader PROFESSOR Philip Davies
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This practical work module develops and applies principles and techniques learnt at the Undergraduate level. New experimental techniques appropriate to synthetic and instrumental projects will be explored and the relationship between theory and experiment will be illustrated in practical based problem-solving exercises. The module also involves a group project where you work in teams, addressing aspects of a particular chemical problem. The teams write technical reports on their work and present the data to the whole class in a group discussion. Finally, you write an individual paper in the RSC Chemical Communications format presenting the findings from the class experiment. 

 

A further individual task is to create a video presentation explaining to a general audience a chemical-based issue, along with a short literature review of the subject area. 

On completion of the module a student should be able to

  • Critically assess practical methodologies and have the ability to employ appropriate equipment for an experiment. 

  • Have a critical awareness of COSHH data and equipment safety protocols to enable comprehensive evaluation of safety and hazard information for chemical procedures. 

  • Analyse and develop an appropriate experimental strategy to investigate a problem. 

  • Work with a team to create a group report and presentation. 

  • Write a scientific paper based on a number of different data sets using sound judgement and evaluation. 

  • Produce video sources that are informative and engaging and demonstrate self-direction and autonomous planning.   

How the module will be delivered

This practical module consists of short mini-research tasks covering the areas of both synthetic and instrumental chemistry. In the synthetic laboratory, you will typically undertake five or six practical tasks and for selected, representative tasks, submit a report on their own experimental results. 

For the instrumental section, the you will work in small teams to investigate a specific problem set for the class, using cutting edge equipment based in research laboratories. Each team reports their findings to the class in the form of a report and presentation. You then, individually, write up the class findings as a scientific paper. 

 

A final part of the module involves the preparation of an individual video explaining some aspect of chemistry along with an accompanying short report providing written information on the background to the talk material. Help is provided by the School for preparing the videos. 

Skills that will be practised and developed

 

Intellectual skills  

  • In-depth interpretation and analysis of experimental data and deduction of properties and potentials in the light of an existing model for a system.  

  • Critically assess new experimental data into the context of what was known/available information.  

  • Assess and demonstrate a comprehensive understanding the current state of knowledge of a system from a literature survey.  

Chemistry-specific skills  

  • Evaluate and show comprehensive awareness of the risks associated with the use of chemicals and apparatus;  

  • Record experimental data in an organised manner and present a written report and oral discussion clearly and concisely;  

  • Competently carry out appropriate experiments to tackle a problem and show a critical ability to interpret results to develop new hypotheses from the data obtained.  

 

Employability skills:      

    

This module is delivered and aligns with the following University Graduate Attributes:      

    

  • Contribute positively and effectively when working in a team, having an impact from the outset.    

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.    

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.    

  • Listen to and take account of the views of others.    

  • Communicate complex ideas effectively to diverse audiences.    

  • Contribute to discussions, negotiate, and present with impact.    

  • Deliver, accept, and act on constructive feedback.     

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.    

  • Consider own personal and professional ethical, social and environmental responsibilities.    

  • Demonstrate personal and professional integrity, reliability and competence.    

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals    

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.    

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding.   

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.    

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.    

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.    

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.    

  • Understanding organisations, their stakeholders, and their impact on the economy    

  • Actively reflect on own studies achievements and self-identity    

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.    

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.    

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.    

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning.   

 

Graduate Attributes – Assessment:   

 

Practical-Based Assessment                    75%  

  • Contribute positively and effectively when working in a team, having an impact from the outset.    

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.    

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.    

  • Listen to and take account of the views of others.    

  • Communicate complex ideas effectively to diverse audiences.    

  • Contribute to discussions, negotiate, and present with impact.    

  • Deliver, accept, and act on constructive feedback.     

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.    

  • Consider own personal and professional ethical, social and environmental responsibilities.    

  • Demonstrate personal and professional integrity, reliability and competence.    

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals    

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.    

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding.   

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.    

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.    

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.    

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.    

  • Understanding organisations, their stakeholders, and their impact on the economy    

  • Actively reflect on own studies achievements and self-identity    

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.    

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.    

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.    

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning.   

  

  

Presentation                                    25%  

  • Contribute positively and effectively when working in a team, having an impact from the outset.    

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.    

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.    

  • Listen to and take account of the views of others.    

  • Communicate complex ideas effectively to diverse audiences.    

  • Contribute to discussions, negotiate, and present with impact.    

  • Deliver, accept, and act on constructive feedback.     

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.    

  • Consider own personal and professional ethical, social and environmental responsibilities.    

  • Demonstrate personal and professional integrity, reliability and competence.    

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals    

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.    

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding.   

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.    

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.    

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.    

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.    

  • Understanding organisations, their stakeholders, and their impact on the economy    

  • Actively reflect on own studies achievements and self-identity    

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.    

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.    

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.    

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning.   

  

Sustainable Development Goals:       

    

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

   

Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture   

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, and decent work for all    

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation.   

Goal 12. Ensure sustainable consumption and production patterns.    

Goal 13. Take urgent action to combat climate change and its impacts.   

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development  

 

How the module will be assessed

 

This module will be assessed continuously on written reports, samples of compounds prepared, spectroscopic and analytical data, and performance in the laboratory. The group presentation, group report and individual papers also contribute to the overall mark. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

 Practical work cannot be repeated after the scheduled time for the module is over. Reassessment for the module will therefore involve completing the written assessments based, either on the student’s own data or on data supplied for the experiments. 

Assessment Breakdown

Type % Title Duration(hrs)
Practical-Based Assessment 75 Lab Work and Written Reports N/A
Presentation 25 Video Presentation and Literature Overview N/A

Syllabus content

This practical module introduces some advanced skills in synthetic chemistry. It also involves applying knowledge from previous modules to interpret data from a number of advanced spectroscopic and microscopic methods.


CHT555: Application of Research Methods (10)

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT555
External Subject Code 100417
Number of Credits 10
Level L7
Language of Delivery English
Module Leader PROFESSOR Philip Davies
Semester Spring Semester
Academic Year 2025/6

Outline Description of Module

This module of practical work develops and applies principles and techniques learnt in an Undergraduate programme. New experimental techniques appropriate to synthetic and instrumental projects will be explored and the relationship between theory and experiment will be illustrated in practical based problem-solving exercises. Students write an individual paper in the RSC Template format presenting the findings from their experiment.

A further individual task is to create a video presentation explaining to a general audience a chemical-based issue, along with a short literature review of the subject area. 

On completion of the module a student should be able to

  • Critically assess practical methodologies and have the ability to employ appropriate equipment for an experiment. 

  • Have a critical awareness of COSHH data and equipment safety protocols to enable comprehensive evaluation of safety and hazard information for chemical procedures. 

  • Analyse and develop an appropriate experimental strategy to investigate a problem. 

  • Write a scientific paper based on a number of different data sets using appropriate evaluations and analysis. 

  • Produce video sources that are informative and engaging and demonstrate self-direction and autonomous planning.   

How the module will be delivered

This practical module consists of short mini-research tasks covering the areas of synthetic and/or instrumental chemistry. In the synthetic laboratory, students will typically undertake two or three practical tasks and submit a report on their own experimental results. For the instrumental section, the students will work in small teams to investigate a specific problem set for the class, using cutting edge equipment based in research laboratories. Each team reports their findings to the class in the form of a report and presentation. Students then, individually, write up the class findings as a scientific paper. A final part of the module involves the preparation of individual video explaining some aspect of chemistry. Help is provided by the School for preparing the videos. 

Skills that will be practised and developed

Intellectual skills 

 

  • In-depth interpretation and analysis of experimental data and deduction of properties and potentials in the light of an existing model for a system. 

  • Critically assess new experimental data into the context of what was known/available information. 

  • Assess and demonstrate a comprehensive understanding the current state of knowledge of a system from a literature survey. 

 

Chemistry-specific skills 

 

  • Evaluate and show comprehensive awareness of the risks associated with the use of chemicals and apparatus; 

  • Record experimental data in an organised manner and present a written report and oral discussion clearly and concisely; 

  • Competently carry out appropriate experiments to tackle a problem and show a critical ability to interpret results to develop new hypotheses from the data obtained. 

 

Employability skills:     

   

This module is delivered and aligns with the following University Graduate Attributes:     

   

  • Contribute positively and effectively when working in a team, having an impact from the outset.   

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.   

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.   

  • Listen to and take account of the views of others.   

  • Communicate complex ideas effectively to diverse audiences.   

  • Contribute to discussions, negotiate, and present with impact.   

  • Deliver, accept, and act on constructive feedback.    

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.   

  • Consider own personal and professional ethical, social and environmental responsibilities.   

  • Demonstrate personal and professional integrity, reliability and competence.   

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals   

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.   

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding.  

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.   

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.   

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.   

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.   

  • Understanding organisations, their stakeholders, and their impact on the economy   

  • Actively reflect on own studies achievements and self-identity   

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.   

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.   

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.   

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning.  

 

Graduate Attributes – Assessment:  

 

Practical-Based Assessment                    50% 

  • Contribute positively and effectively when working in a team, having an impact from the outset.   

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.   

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.   

  • Listen to and take account of the views of others.   

  • Communicate complex ideas effectively to diverse audiences.   

  • Contribute to discussions, negotiate, and present with impact.   

  • Deliver, accept, and act on constructive feedback.    

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.   

  • Consider own personal and professional ethical, social and environmental responsibilities.   

  • Demonstrate personal and professional integrity, reliability and competence.   

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals   

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.   

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding.  

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.   

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.   

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.   

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.   

  • Understanding organisations, their stakeholders, and their impact on the economy   

  • Actively reflect on own studies achievements and self-identity   

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.   

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.   

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.   

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning.  

 

Video Presentation                                    50% 

  • Contribute positively and effectively when working in a team, having an impact from the outset.   

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.   

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.   

  • Listen to and take account of the views of others.   

  • Communicate complex ideas effectively to diverse audiences.   

  • Contribute to discussions, negotiate, and present with impact.   

  • Deliver, accept, and act on constructive feedback.    

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.   

  • Consider own personal and professional ethical, social and environmental responsibilities.   

  • Demonstrate personal and professional integrity, reliability and competence.   

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals   

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.   

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding.  

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.   

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.   

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.   

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.   

  • Understanding organisations, their stakeholders, and their impact on the economy   

  • Actively reflect on own studies achievements and self-identity   

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.   

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.   

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.   

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning.  

 

Sustainable Development Goals:      

   

This module is delivered and aligns in working towards the following Sustainable Development Goals:  

  

Goal 2. End hunger, achieve food security and improved nutrition and promote sustainable agriculture  

Goal 8. Promote sustained, inclusive, and sustainable economic growth, full and productive employment, and decent work for all   

Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation.  

Goal 12. Ensure sustainable consumption and production patterns.   

Goal 13. Take urgent action to combat climate change and its impacts.  

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development 

How the module will be assessed

This module will be assessed continuously on the basis of written reports, samples of compounds prepared, spectroscopic and analytical data, and performance in the laboratory. When applicable, the group presentation, group report and individual papers also contribute to the overall mark. 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE:  

Practical work cannot be repeated after the scheduled time for the module is over. Reassessment for the module will therefore involve completing the written assessments based, either on the student’s own data or on data supplied for the experiments. 

Assessment Breakdown

Type % Title Duration(hrs)
Practical-Based Assessment 50 Lab Work and Written Reports N/A
Presentation 50 Video Presentation N/A

Syllabus content

This practical module introduces some advanced skills in synthetic chemistry. It also involves applying knowledge from undergraduate modules to interpret data from a number of advanced spectroscopic and/or microscopic methods. 


CHT580: Practical Chemistry for Sustainability

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT580
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader DR Nicholas Francois Dummer
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module will provide you with some of the key practical skills required for developing as a professional scientist to investigate challenges in sustainability, and to prepare you for your research project. The module will enable you to actively learn analysis and characterisation techniques typically used in different areas of sustainable chemistry through both teamwork and independent study. You will independently make decisions based on your critical evaluation of existing scientific literature, and conceive, plan, execute and communicate outcomes for your practical experiments. As a team, you will need to manage your time and resources in the laboratory and coordinate to produce a final report.  

 

On completion of the module a student should be able to

Obtain and act upon safety and hazard information for chemicals.  

 

Plan a synthetic strategy to efficiently obtain target compounds sustainably, including atom efficiency, energy efficiency and waste reduction.  

 

Identify appropriate analytical methods to gain data on reactions being carried out. 

 

Measure and interpret analytical data using critical judgement to assess quality and significance of data.  

 

Critically evaluate experimental results in the relevant literature to evaluate the significance of findings. 

 

Address chemical challenges in sustainability and communicate these complex ideas effectively.  

How the module will be delivered

 

The module will run across both semesters with foundational laboratory skills being introduced in the autumn semester and more advanced practical experiments being conducted in the Spring Semester with 8 x 6 hours laboratory sessions typical in the Spring.  

 

This module will be practical based and will be delivered as a series of experiments taking place in the School’s teaching laboratories with some activities introducing our research laboratories. Experiments cover preparation of heterogenous catalysts, homogenous catalysis, organic coupling reactions and computational chemistry under the umbrella of sustainable chemistry as achieved by lowering the energy of a process (physical chemistry), exploring alternative earth abundant metals for catalytic processes (inorganic chemistry), atom efficiency and polymer recycling (organic chemistry). Some activities will be group activities, involving both individual experimentation followed by group work to look at individually acquired findings as a large data set.  The quality of good laboratory practice and teamworking will be assessed by a mix of peer assessment and demonstrator evaluation. 

 

Guidance in basic laboratory safety procedures and experiment preparation will be delivered by module tutors at scheduled meetings ahead of lab sessions and through preliminary exercises on learning central. 

Demonstrators will provide guidance during laboratory sessions and feedback on record keeping ahead of submission. 

 

Skills that will be practised and developed

 

Skills developed through formal module learning outcomes and summative assessment include:  

  

Academic Skills: 

  • You will analyse experimental data, exercising critical judgement in evaluating significance of results.  

  • You will develop the ability to communicate complex scientific concepts in a clear and accessible manner developing effective communication skills. 

 

  • Discipline Specific Skills: 

  • You will develop critical thinking and appropriate laboratory practice for assessment and handling of potentially harmful chemical materials. 

  • You will develop analytical thinking to identify the appropriate experimental techniques in synthesis and characterisation within a modern laboratory environment. 

  • You will communicate hypotheses and justify conclusions in reporting experimental results. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

  

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.   

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability and competence.  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

 

Assessment 

The presentation and in-lab assessments (25% each) will assess the following learning outcomes in particular. 

  • Obtain and act upon safety and hazard information for chemicals.  

  • Contribute when working in a team, addressing chemical challenges in sustainability and communicate these complex ideas effectively.  

 

The written reports will assess the following learning outcomes. 

  • Obtain and act upon safety and hazard information for chemicals.  

  • Plan a synthetic strategy to efficiently obtain target compounds sustainably, including atom efficiency, energy efficiency and waste reduction.  

  • Identify appropriate analytical methods to gain data on reactions being carried out. 

  • Measure and interpret analytical data using critical judgement to assess quality and significance of data.  

  • Critically evaluate experimental results in the relevant literature to evaluate the significance of findings. 

 

 

 

Sustainable Development Goals:       

 

This module is delivered and aligns in working towards the following Sustainable Development Goals in particular: 

 

  • Goal 4. Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all.  

  • Goal 9. Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation. 

  • Goal 12. Ensure sustainable consumption and production patterns. 

  • Goal 13. Take urgent action to combat climate change and its impacts 

 

 

How the module will be assessed

The assessment methods for the Module should be detailed here (both formative and summative), including any distinctive features (e.g., major project work).  

 

You should explain how each assessment will enable all students to demonstrate achievement of the Module learning outcomes, indicating which learning outcomes are addressed in each assessment task.   

 

In addition, you must append a specific marking criteria to this Module description for each assessment e.g., coursework, group work, presentation etc.  It is the marking criteria which distinguishes the level of achievement and differentiates between satisfactory, good, and excellent student performance in the module assessment.   

 

Students must have the opportunity to understand how their assessment will be marked and how the feedback corresponds directly to the marking criteria. 

 

Assessment for this module will involve student submissions from combined data sets from group experiments and individual data sets from independent study. Assessments will be in the form of group presentations, written reports and in lab safety and skills assessments. An individual written report will be used to assess the student’s ability to summarise current literature, present and critically evaluate primary data with respect to the literature in the form of a scientific journal article. Reports will be assessed by a module tutor. Formative assessment and feedback will be given continuously throughout the module, by laboratory demonstrators and supervisors, on practical skills and data interpretation.  From group work there will be a 20% weighting in peer assessment for the in-lab skills element to assess each student’s contribution and ability to work in a team.  Group members will be given individual marks. Staff will contribute 80% of the mark and students will also be able to self-assess confidentially and so highlight any areas for staff to be aware where there may be team-conflict or extenuating circumstance (which should be evidenced through the extenuating circumstances procedure provided by the University).   

 

 

 

 

Any academic or competence standards which may limit the availability of adjustments or alternative assessments for disabled students should be clearly stated in line with guidance provided in the Reasonable Adjustment Policy and Procedure 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

Practical work cannot be repeated after the scheduled time for the module is over. Reassessment involves completing the written assessments based on the student’s own data. Students who need to repeat the laboratory work or fail to pass the pre-lab safety and skills assessment will be required to resit as an internal student in the next academic session. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

Please provide information to the student about the opportunity for reassessment, should they fail the Module. You should explain the format that reassessment.  

 

If the reassessment is in a different format to the original assessment, you will need to show how it continues to meet the module level learning outcomes. 

Assessment Breakdown

Type % Title Duration(hrs)
Presentation 25 Presentation N/A
Report 25 Written Report N/A
Report 25 Written Report N/A
Laboratory Work 25 In Lab Safety and Skills Assessment N/A

Syllabus content

This section should provide a descriptive outline and summary of the topics to be covered during the Module. This should distinguish clearly between mandatory content and areas where students may choose between options or develop their own topics.  It should not provide a precise week by week timetable as it may be subject to change.  The use of Module Maps will provide students with weekly details.  

 

The practical module will contain a series of experiments based around different aspects of sustainable chemistry including catalysis, materials synthesis and energy efficient synthesis. 

 

Several different synthetic and analytical techniques will be used to understand the chemistry and evaluate the sustainability of the processes investigated. 

 

 


CHT600: Core Chemistry for Sustainability

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT600
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Professor Marc Pera Titus
Semester Autumn Semester
Academic Year 2025/6

Outline Description of Module

This module provides students with the principles and metrics of sustainability in chemical reactions and processes within the context of the UN Sustainable Development Goals. This module will enable you to learn and critically apply a full range of advanced concepts in chemistry to the design of sustainable and circular reactions. The module is divided into several subject areas that will be assessed separately and begin with introductory lectures by distinguished experts in the fields of recyclable catalytic systems, novel sustainable inorganic materials, computational modelling, and biotechnological production of raw materials, including polymers and fine chemicals with key themes in Sustainable Energy, Sustainable Materials, Sustainable Health and Sustainable Food. 

 

On completion of the module a student should be able to

Having successfully completed this module you will be able to: 

  • Evaluate methodologies for assessing (quantifying) the sustainability of chemical and energy-related processes and impact of catalysis  

  • Critically assess the opportunities for novel computing methodologies to drive chemistry for sustainability. 

  • Conceive novel energy sources and processes for large-scale chemical reactions and novel materials capable of selective capture of greenhouse gases. 

  • Gain systematic understanding on how energy and chemical feedstocks can be sustainably sourced from renewable feedstocks and waste to achieve circularity. 

  • Creatively apply concepts from underpinning chemistry for the move towards a completely sustainable production of fertilisers for soils and health and other rhizosphere related resources. 

  • Critically evaluate the chemistry underpinning biotechnological medicine discovery and production, and to benefit existing sustainable approaches and early diagnosis.  

  • Critically analyse critical data to evaluate processes for claims of sustainability, decarbonization and circularity and identify greenwashing. 

How the module will be delivered

 

This module will be delivered through a blended approach featuring face to face delivery, group work and online activities.  Each key theme (energy, materials, health and food) will be introduced by a keynote lecture from one of our most distinguished scientists followed by a mix of interactive lectures, academic-led seminars and group work. 

Some background material and visiting lecturers (industrialists for example) may deliver material online. 

This module will feature a group project on chemistry for sustainability –  for example, take one chemical or process or sustainability challenge and deliver a plan on how to improve sustainability in its production/lifecycle - with metrics. Assessment will be through individual reports and a presentation. 

 

Skills that will be practised and developed

Chemistry-Specific Skills 

  • You will gain advanced skills in quantifying the sustainability of a reaction/process. 

  • Implementation of digital methods for sustainability will be developed. 

  • You will learn to critically identify and apply sustainable feedstocks to access chemicals, fuels and generate energy. 

  • Catalyst/Enzyme discovery for sustainable manufacture (products and processes) will be introduced and developed. 

  • You will gain an advanced understanding of mechanism in chemical reactions and gain skills in applying it to unseen problems. 

 

Employability Skills 

You will develop collaborative skills by contributing positively and effectively when working in a team to design posters and when conducting team experiments. 

You will become an effective communicator by communicating scientific ideas to diverse audiences. 

You will gain independence and critical thinking skills through analysis of complex experimental data, drawing conclusions from this and proposing new ideas and experiments.  

Time management skills will be developed through constraints in time available to perform experiments and collaborative work. 

 

 

The module is delivered and aligns with the following University Graduate Attributes 

 

Collaborative 

  • Contribute positively and effectively when working in a team, having an impact from the outset. 

  • Demonstrate enthusiasm and the ability to motivate themselves and positively influence others in meeting agreed responsibilities. 

 

Effective Communicator 

  • Listen to and take account of the view of others. 

  • Communicate complex ideas effectively to diverse audiences. 

  • Contribute to discussions, negotiate and present with impact. 

  • Deliver, accept and act on constructive feedback. 

 

Ethically, Socially and Environmentally Aware 

  • Consider own personal and professional ethical, social and environmental responsibility. 

  • Be mindful of the climate emergency and the UN’s Sustainability Development Goals. 

 

Independent and Critical Thinkers 

  • Identify, define and analyse complex issues and ideas, exercising critical judgement in evaluating sources of information. 

  • Demonstrate Intellectual Curiosity and engage in in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures. 

 

Innovative, Enterprising and Commercially Aware. 

  • Generate original ideas and apply creative, imaginative and innovative thinking in response to identified needs and problems. 

  • Understand organisations, their stakeholders and their impact on the community. 

 

Reflective and Resilient 

  • Engage with new ideas, opportunities and technologies, building knowledge and experience to make informed decisions about own future. 

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts. 

 

 

 

Sustainability Development Goals 

This module is delivered and will include material working towards all seventeen of the UN’s Sustainable Development Goals.  The following ones will get the greatest focus. 

 

Goal 2. Zero Hunger. End hunger, achieve food security and improved nutrition and promote sustainable agriculture. 

Goal 3. Good Health and Wellbeing. Ensure healthy livers and promote well-being for all at all ages. 

Goal 6. Clean Water and Sanitation. Ensure availability and sustainable management of water and sanitation for all. 

Goal 7. Affordable and Clean energy. Ensure access to affordable, reliable, sustainable and modern energy for all. 

Goal 8. Decent work and economic growth. Promote sustained, inclusive and sustainable economic growth full and productive employment and decent work for all. 

Goal 9. Industry, innovation and infrastructure. Build resilient infrastructure, promote inclusive and sustainable industrialisation and foster innovation. 

Goal 12. Responsible consumption and production. Ensure sustainable consumption and production patterns. 

Goal 13.  Climate Action. Take urgent action to combat climate change and its impacts. 

Goal 17.  Strengthen the means of implementation and revitalise the global partnership for sustainable development (Science and Technology). 

 

How the module will be assessed

Summative assessment 

  • Oral group presentation 40% overall weighting.  25% Peer marking with 75% weighting on academic staff marking – the talks will take place in a scheduled session with several members of staff in attendance who will mark all presentations. The group presentation will feature first to lay the basis and foundation of the later report. This will build and assess your collaborative working skills (teamworking), debating skills and critical thinking skills. Staff will provide formative feedback on draft slides in the week prior to the presentation. 

 

  • Written report. 60% - approximately 5 pages. This will be on a chemical aspect of a broad-picture sustainability challenge or goal.  This will be based on the initial group work but be focused on an individual aspect of the broader challenge.  This will assess your capabilities for individual research of the published literature and written communication skills.  The module tutors will provide feedback on an initial draft at least two weeks prior to submission. 

 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme.  If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme.  You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

You must resit any component of this module that has been failed in the August resit period.  In the case of presentations, an individual presentation or video will be arranged where it is not appropriate for the entire group to present. 

 

In the event of a resit being necessary for the group oral presentation – you will be required to be reassessed on the basis of an individual presentation for that assessment component. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

Please provide information to the student about the opportunity for reassessment, should they fail the Module. You should explain the format that reassessment.  

 

If the reassessment is in a different format to the original assessment, you will need to show how it continues to meet the module level learning outcomes. 

 

Assessment Breakdown

Type % Title Duration(hrs)
Presentation 40 Oral Presentation N/A
Report 60 Written Report N/A

Syllabus content

General introduction to UN’s sustainability development goals and the 12 principles of Green Chemistry. 

  • Waste minimisation and atom-economy 

  • Energy efficiency 

  • Life cycle analysis 

  • Zero carbon approaches to chemistry 

  • Minimisation of pollution and renewable resources 

  • Critically analyse greenwashing claims through analysis of reliable data 

 

 

Methodologies for assessing (quantifying) the sustainability of chemical and energy-related processes and impact of catalysis. 

  • E-factor, atom efficiency,  

  • techno-economic & life-cycle assessment. 

 

Computing methodologies 

  • General introduction to computational chemistry and it useuse it to understand and plan chemical processes to minimise waste in experimentation. 

  • AI and targeted use of common architectures, on driving sustainability in chemistry. 

 

Novel energy sources and processes for large-scale chemical reactions 

e.g.  

  • for reduction of atmospheric nitrogen to ammonia 

  • novel materials capable of selective capture of greenhouse gases. 

 

Energy and chemical feedstocks 

  • Renewable feedstocks (e.g., biomass) and waste (e.g., end-of-life plastics, conversion of thermosets) to achieve circularity. 

 

Sustainability in human health 

  • Current unsustainable trends in pharmaceutical manufacture and health practice and analysis of possible solutions. 

  • Chemistry underpinning biotechnological medicine discovery and production, and to benefit existing sustainable approaches and early diagnosis.  

 

 

Food security and sustainable agriculture 

  • Chemistry that can lead us towards sustainable production of fertilisers for soils and health and other rhizosphere related resources. 

  • Reduction of greenhouse gas emission from animal husbandry 

  • Solutions for greenhouse gas emissions in arable farming. 

  • Chemical ecology – environmentally benign crop protection from disease and predation. 

 

 


CHT716: Colloquium

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT716
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Dr Andrea Folli
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

Outline Description of Module 

 

This module trains you in searching, retrieving relevant information. Subsequently, analysis and critical discussion of current scientific literature in various areas of research.  

 

The module will develop written communication skills through the preparation of a written literature review report in one of the standard formats (e.g. RSC and ACS). The module will also develop oral communication skills involving the presentation of current research papers, with critical discussion of merit of research or its limitations. As the course progresses, the focus of subject will be on areas of chemistry related to specialised topic of the proposed Part II project. 

 

You will work on your own specialised report, typically aligned with the topic of your Part II project. 

 

On completion of the module a student should be able to

 

  • Search, rapidly assess, and critically review specific areas of scientific literature. 

  • Critically evaluate the published interpretations of data and persuasively inform others, of varying expertise, of the validity of the work. 

  • Develop and support a professional opinion in a specialised area of knowledge using scientific literature. 

  • Report (in writing and orally) chemical information at a professional standard. 

How the module will be delivered

The module is delivered through two 2-hour workshops on handling scientific literature. Further support on reviewing scientific literature and delivering presentations is provided through a wide range of material for self-study as required in learning modules on Learning Central.  

During the autumn semester there will be a weekly seminar session which will be a journal club, each student presenting an academic research paper regarding chemistry for sustainability and an academic member of staff will lead a critical discussion of the work presented.  There will be support sessions in communication and outreach in addition. 

Supervision during the preparation of a written report and a presentation will be provided by the member of staff proposing the topic of the literature study. A minimum of three meetings between the student and the project supervisor is anticipated (one to discuss the topic of the review, one to discuss an early draft of the literature review and one to discuss a late draft of the literature review). 

These meetings will enable and support student learning of complex and specialised knowledge and skills, but the student is expected to develop the autonomous learning processes associated with the preparation of critical literature reviews. 

Skills that will be practised and developed

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

  

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Identify organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Graduate Attributes – Assessment:    

  

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Identify organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Identify organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development 

How the module will be assessed

The presentation and the report will allow the student to:  

 

(a) demonstrate his/her ability to judge and critically review a significant body of existing literature in a specialised area of research;  

 

(b) present results from a study of the scientific literature in both written and oral form. The assessment criteria are provided to you on Learning Central in the form of the marking forms used by the markers. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

The format of the reassessment is the same as the format of the original assessments. 

Assessment Breakdown

Type % Title Duration(hrs)
Dissertation 20 Written Review N/A
Presentation 30 Oral Presentation N/A
Dissertation 50 Written Review N/A

Syllabus content

 

  • Application of information technology in chemistry 

  • Writing of reports in one of the standard formats in chemistry 

  • Plagiarism and its potential consequences 

  • Oral presentation and scientific discussion 

  • The module consists of a literature review of a specialised area of knowledge, resulting in a written report and an oral presentation. You are allocated a supervisor and agree a topic which can be in any area of your MSc programme but must be focussed on chemical aspects of the selected topic.  


CHT720: Colloquium for Sustainability

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT720
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Dr Andrea Folli
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

This module trains students in searching, retrieving, managing and subsequent analysis and critical discussion of current scientific literature in a specialised area of research aimed at driving forward chemistry relating to improving global sustainability.  

 

The module will develop written communication skills through the preparation of a written literature review report in one of the standard formats (e.g. RSC and ACS). The module will also develop oral communication skills.  

 

In semester 1 this module will comprise a weekly group journal club where a significant academic article on a topic of sustainability will be analysed and critiqued in a group discussion led by the students with academic supervision.  Early group sessions will provide guidance through which discussion that follow may be framed. It will also feature group seminars with prominent academics and industrialists (both internal to Cardiff and external) contributing as guest speakers on a current topic in chemistry for sustainability. 

 

In Semester 2 each student will work on their own specialised chemical topic and these topics are typically aligned with the topic of the student’s assigned Part II project. 

On completion of the module a student should be able to

 

  • Collect, manage, and critically review a body of scientific literature in a specialised area of knowledge. 

  • Critically evaluate the published interpretations of data and generate alternative interpretations where appropriate. 

  • Develop and support a professional opinion in a specialised area of knowledge using scientific literature. 

  • Report (in writing and orally) chemical information at a professional standard. 

   

How the module will be delivered

The module is delivered through two 2-hour workshops on handling scientific literature. Further support on reviewing scientific literature and delivering presentations is provided through a wide range of material for self-study as required in learning modules on Learning Central.  

 

During the autumn semester there will be a weekly seminar session which will be a journal club, each student presenting an academic research paper regarding chemistry for sustainability and an academic member of staff will support a student led critical discussion of the work presented.  There will be support sessions in communication and outreach in addition. 

 

At the end of the autumn semester there will be an assessed poster session where each student will present a poster introducing themselves and their ambition for a sustainable future alongside a chosen current topic in chemistry for sustainability presenting a challenge and a possible solution (or solutions). 

Supervision during the preparation of a written report and a presentation will be provided by the member of staff proposing the topic of the literature study. A minimum of three meetings between the student and the project supervisor is anticipated (one to discuss the topic of the review, one to discuss an early draft of the literature review and one to discuss a late draft of the literature review). 

 

These timetabled meetings will enable and support student learning of complex and specialised knowledge and skills, but the student is expected to develop the autonomous learning processes associated with the preparation of critical literature reviews. 

Skills that will be practised and developed

 

Academic skills 

  • Interpret complex scientific information and critically relate to broad challenges towards global sustainability challenges that can be addressed through application of chemical processes. 

  • Research and interrelate information in the chemical literature, government policy documents, business reports and other broad information databases to find and evaluate data that is relevant and accurate. 

  • Communication, through a variety of dissemination formats, complex data, critical evaluation and propose solutions to sustainability challenges to a variety of audiences with different levels of scientific literacy. 

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

  

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Identify organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  Sustainable Development Goals:     

  

This module is delivered and aligns in working towards all seventeen of the UN’s sustainability goals 

 

How the module will be assessed

The poster will provide early practice in demonstrating an ability to practice critical review of the literature and presentation of potential innovations for the future in chemistry for sustainability. Feedback on a draft version of the poster will be provided by an academic member of staff prior to submission. 

The presentation and the report will allow the student to:  

(a) demonstrate their ability to judge and critically review a significant body of existing literature in a specialised area of research;  

(b) present results from a study of the scientific literature in both written and oral form. The assessment criteria are provided to students on Learning Central in the form of the marking forms used by the markers. 

There will be regular timetabled supervision sessions (minimum once every two weeks) with your appointed supervisor in the second semester and you will be expected to provide regular written updates on progress and hence receive regular feedback on progress ahead of the final submissions. 

   

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

The format of the reassessment is the same as the format of the original assessments. 

Assessment Breakdown

Type % Title Duration(hrs)
Presentation 20 Poster Presentation N/A
Presentation 30 Oral Presentation N/A
Dissertation 50 Written Review N/A

Syllabus content

 

  • Application of information technology in chemistry for sustainability 

  • Writing of reports in one of the standard formats in chemistry 

  • Plagiarism and its potential consequences 

  • Oral presentation and scientific discussion 

  • The module consists of a literature review of a specialised area of knowledge, resulting in a written report and an oral presentation. Students are allocated a supervisor and agree a topic which can be in any area of the student’s MSc programme but must be focussed on chemical aspects of the selected topic. 


CHT725: Colloquium for Medicinal Chemistry

School Cardiff School of Chemistry
Department Code CHEMY
Module Code CHT725
External Subject Code 100417
Number of Credits 20
Level L7
Language of Delivery English
Module Leader Dr Andrea Folli
Semester Double Semester
Academic Year 2025/6

Outline Description of Module

 

This module trains you in searching, retrieving, managing and subsequent analysis and critical discussion of current scientific literature in a specialised area of research.  

 

The module will develop written communication skills through the preparation of a written literature review report in one of the standard formats (e.g. RSC and ACS). The module will also develop oral communication skills.  

 

Each student works on their own specialised chemical topics and these topics are typically aligned with the topic of the student’s Part II project. 

 

On completion of the module a student should be able to

 

  • Collect, manage, and critically review a body of scientific literature in a specialised area of knowledge. 

  • Critically evaluate the published interpretations of data and generate alternative interpretations where appropriate. 

  • Develop and support a professional opinion in a specialised area of knowledge using scientific literature. 

  • Report (in writing and orally) chemical information at a professional standard. 

How the module will be delivered

 

The module is delivered through two 2-hour workshops on handling scientific literature. Further support on reviewing scientific literature and delivering presentations is provided through a wide range of material for self-study as required in learning modules on Learning Central.  

 

Supervision during the preparation of a written report and a presentation will be provided by the member of staff proposing the topic of the literature study. A minimum of three meetings between the student and the project supervisor is anticipated (one to discuss the topic of the review, one to discuss an early draft of the literature review and one to discuss a late draft of the literature review).  

 

These meetings will enable and support student learning of complex and specialised knowledge and skills, but the student is expected to develop the autonomous learning processes associated with the preparation of critical literature reviews. 

Skills that will be practised and developed

 

Employability skills:    

  

This module is delivered and aligns with the following University Graduate Attributes:    

  

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Identify organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Graduate Attributes – Assessment:    

 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Identify organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

 

  • Contribute positively and effectively when working in a team, having an impact from the outset.  

  • Demonstrate enthusiasm and the ability to motivate themselves, and positively influence others in meeting agreed responsibilities.  

  • Be respectful of the roles of others and acknowledge the limits of their own skills/experience.  

  • Listen to and take account of the views of others.  

  • Communicate complex ideas effectively to diverse audiences.  

  • Contribute to discussions, negotiate, and present with impact.  

  • Deliver, accept, and act on constructive feedback.  

  • Take a professional approach to communication, including their own online/social media profiles, and be alert to how words and actions may be interpreted.  

  • Consider own personal and professional ethical, social, and environmental responsibilities.  

  • Demonstrate personal and professional integrity, reliability, and competence.  

  • Identify organisations, their stakeholders, and their impact on the community.  

  • Actively take responsibility for promoting human rights, celebrating diversity, and widening inclusion  

  • Be mindful of the Climate Emergency and the UN's Sustainable Development Goals  

  • Act as global citizens, engaging with and valuing cultural difference through practical experience of other countries.  

  • Identify, define, and analyse complex issues and ideas, exercising critical judgment in evaluating sources of information.  

  • Demonstrate intellectual curiosity and engage in the pursuit of new knowledge and understanding. 

  • Investigate problems and offer effective solutions, reflecting on and learning from successes and failures.  

  • Generate original ideas and apply creative, imaginative, and innovative thinking in response to identified needs and problems.  

  • Take the initiative to act on own ideas and the ideas of others, balancing risk and returns and making things happen.  

  • Be confident in pursuing entrepreneurship as a visible and rewarding career path.  

  • Understanding organisations, their stakeholders, and their impact on the economy  

  • Actively reflect on own studies achievements and self-identity  

  • Demonstrate resilience, adaptability, and creativity in dealing with challenges, and be open to change.  

  • Identify and articulate own skills, knowledge and understanding confidently and in a variety of contexts.  

  • Engage with new ideas, opportunities, and technologies, building knowledge and experience to make informed decisions about own future.  

  • Set aspirational goals for continuing personal and professional development, planning effectively with a commitment to lifelong learning. 

 

  

Sustainable Development Goals:     

  

This module is delivered and aligns in working towards the following Sustainable Development Goals:   

 

Goal 17. Strengthen the means of implementation and revitalize the Global Partnership for Sustainable Development 

How the module will be assessed

The presentation and the report will allow the student to:  

 

(a) demonstrate his/her ability to judge and critically review a significant body of existing literature in a specialised area of research;  

 

(b) present results from a study of the scientific literature in both written and oral form. The assessment criteria are provided to you on Learning Central in the form of the marking forms used by the markers. 

 

THE OPPORTUNITY FOR REASSESSMENT IN THIS MODULE: 

 

Opportunities for re-assessment is only permitted provided you have not failed more credit than in the resit rule adopted by your programme. If the amount of credit you have failed is more than permitted by the relevant resit rule, you may be permitted to repeat study if you are within the threshold set for the Repeat rule adopted by your programme. You will be notified of your eligibility to resit/repeat any modules after the Examining Board in the Summer period. 

 

All resit assessments will be held in the Resit Examination period, prior to the start of the following academic session

 

The format of the reassessment is the same as the format of the original assessments. 

Assessment Breakdown

Type % Title Duration(hrs)
Presentation 20 Poster Presentation N/A
Dissertation 50 Written Review N/A
Presentation 30 Oral Presentation N/A

Syllabus content

  • Application of information technology in chemistry 

  • Writing of reports in one of the standard formats in chemistry 

  • Plagiarism and its potential consequences 

  • Oral presentation and scientific discussion 

  • The module consists of a literature review of a specialised area of knowledge, resulting in a written report and an oral presentation. You are allocated a supervisor and agree a topic which can be in any area of the student’s MSc programme but must be focussed on chemical aspects of the selected topic. 



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